Resveratrol, which is found in grapes and red wine, has long been considered a superstar in the health food store. Studies have suggested that resveratrol can protect against cancer, cognitive decline and cardiovascular complications.
A new study conducted in Tuscany suggests that people who get more resveratrol by drinking red wine may not get as much protection as previously predicted. The researchers followed nearly 800 older Italians for nine years. Urine specimens were collected at the beginning of the study along with dietary surveys.
During the decade of the study about one third of the participants died. Variations in urinary resveratrol levels were not associated with differences in mortality, heart disease or cancer rates. One significant difference, however, was in cognitive function. People with the highest levels of resveratrol were less likely to be impaired.
This was a relatively small epidemiological study and did not randomize people to receive resveratrol supplements compared to placebo. Instead, the participants dosed themselves by drinking the wine that is abundantly produced in the region. Those who drank more wine had higher levels of resveratrol in their urine.
Critics have pointed out that a single measure of resveratrol might not be representative of intake over the entire decade. Until large, randomized, controlled trials are conducted, we won’t have the definitive answer about the health benefits or risks of resveratrol.
[JAMA Internal Medicine, online May 12, 2014]
To get other ideas about heart healthy supplements and dietary regimens, check out our Guide to Cholesterol Control and Heart Health.
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