Q. Taking Avodart triggered the onset of both erectile dysfunction and reduced ejaculate for me. I took it for two years; my prostate did not shrink, but my penis did.
These sexual side effects linger. Five years later, I still have ED and low ejaculate. The symptom of frequent nightly urination, however, has ceased to be a problem. Will the sexual side effects ever go away?
A. Medications that shrink the prostate include dutasteride (Avodart) and finasteride (Proscar). These drugs are prescribed to treat symptoms of benign prostate enlargement. Lower dose finasteride (Propecia) is also prescribed for male pattern baldness.
A study published in the Journal of Sexual Medicine (Nov. 2012) reported persistent sexual side effects in men who took finasteride. These included reduced sexual arousal, lower ejaculate volume, erection difficulties and inability to reach orgasm. The study subjects also complained of smaller penis size and reduced sensation. It is not clear how long these complications may last. Dutasteride is likely to have similar side effects (Urology, March 2014).