Cymbalta was originally approved by the FDA in 2004 for the treatment of major depression. It is officially an SNRI-type antidepressant. In doctorspeak that means it is a serotonin-norepinehprine reuptake inhibitor and is somewhat similar to other antidepressants such as Effexor (venlafaxine) and Pristiq (desvenlafaxine).

The FDA also approved Cymbalta to treat nerve pain associated with diabetes in 2004. In 2007 the drug got a green light for anxiety and in 2008 the FDA agreed that it could ease the discomfort associated with fibromyalgia. It was also approved to treat musculoskeletal pain associated with arthritis and lower back pain in 2010. In other words, here was a drug that could relieve your blues and your aches and pains. And the drug company that makes Cymbalta (Lilly) has been aggressively marketing it as a good way to deal with chronic low back pain and osteoarthritis. Perhaps you have seen the commercials on TV promoting the pain relieving power of the drug with the slogan “Cymbalta can help.” It sounds almost too good to be true.

Ah…and there is the rub. Although there is a long list of serious side effects mentioned during the commercial, the video images seem quite reassuring and trump the scary message the FDA requires for this medication. So, let’s set the record straight. Here, without visual interference, are a list of potential complications associated with this medication.


• Nausea, stomach pain, constipation, diarrhea, decreased appetite, vomiting
• Dry mouth
• Insomnia, anxiety, tremor
• Dizziness, fatigue, sleepiness
• Sweating, hot flashes
• Blurred vision
• Headache
• Sexual dysfunction, lowered libido, erection difficulties, lack of orgasm
• Liver damage
• Serious skin reactions, rash, hives (requires immediate MD assistance!)
• Glaucoma
• Irregular heart rhythms
• Bleeding problems
• Blood pressure problems
• Interaction with other drugs (leading to serotonin syndrome among other reactions)
• Pneumonia
• Seizures
• Depressed mood, suicidal thoughts and behavior, suicide

Such a long list of side effects makes your eyes glaze over after the top 3 or 4. That is why we have included stories from real people so you can better understand what these complications feel like.

Even though such side effects are scary, there is another problem with Cymbalta. When people try to stop taking this drug they frequently report unpleasant withdrawal symptoms. An organization (QuarterWatch) that monitors the FDA’s database of serious adverse drug events has noted that:

“We observed a signal for serious drug withdrawal symptoms associated with duloxetine (CYMBALTA), a widely used antidepressant that is also approved to treat arthritis and back pain, anxiety, and fibromyalgia. In the first quarter of 2012 the FDA received 48 case reports of drug withdrawal identifying duloxetine as the suspect drug. They described a wide spectrum of withdrawal effects that began when the patients stopped the drug, including blackouts, suicidal thoughts, tremor, and nausea. Several cases involved hospitalization. Probing deeper into the scientific record for duloxetine we found that withdrawal symptoms were reported in 44-50% of patients abruptly discontinuing duloxetine at the end of clinical studies for depression, and more than half of this total did not resolve within a week or two. In addition, we identified a serious breakdown at both the FDA and the manufacturer, Eli Lilly and Company, in providing adequate warnings and instructions about how to manage this common adverse effect.”

Doctors have taken to calling this “discontinuation syndrome.” These clinical words do not do justice to what it is like to stop antidepressants like Cymbalta, Effexor (venlafaxine), Paxil (paroxetine), Pristiq (desvenlafaxine) or Zoloft (sertraline) suddenly.


• Brain “Zaps” (electric shock-like senstations in the brain)
• Dizziness, light-headedness, vertigo, feeling faint
• Headaches
• Anxiety, irritability, hostility
• Nausea, diarrhea, digestive upset
• Tremor, hands shaking, nerve tingles, strange sensations
• Fatigue, tiredness, lack of energy
• Visual disturbances

Again, a list of symptoms does not do this problem justice. Below you will read some stories from people who have posted their comments to this website. We would love to hear your story, positive or negative. Share your experience with Cymbalta or any other antidepressant below.

Should you wish to learn more about dealing with depression through some other strategies, we offer our Guide to Dealing with Depression. You will also find a whole chapter on prescribing mistakes doctors make when treating depression and fibromyalgia in our book, Top Screwups Doctors Make and How to Avoid Them.

“My lovely, young daughter-in law, who was about to celebrate her 29th birthday, was prescribed Cymbalta, Klonopin, and Ambien and has committed suicide.

“She told her physician and her therapist that she’d had thoughts of suicide but no one took her seriously. She suffered from depression, as well as an eating disorder, and had very low body weight. She also used alcohol.

“Please remind your readers of the potentially disastrous effects these chemicals can cause when taken carelessly or in combination with alcohol.”


“I have been on Prozac over the last 20 years off and on and it finally stopped working. The last time I took it about 2 years ago I was taking the generic from Barr – the blue and white capsule. I was feeling as if I were in the deepest dark hole there ever was.

“My doctor put me on Cymbalta from which I had a lot of side effects such as palpitations, feeling constant dread, panic attacks, sweats, lightheadedness and general feeling of not being well.

“She added Abilify which put me over the edge. I was in the worst depression I have ever been in. Finally after living like this for several months, I asked to be put back on Prozac. I was taking the generic from Sandoz. When the prescription ran out I ended up on the big blue and white capsules from Barr.

“Over the last couple of weeks it has been constant crying spells, arguing with everyone and feeling pretty low. I talked to my doctor and she wrote the prescription for Sandoz only generic. The blue and white capsules are like taking a placebo. My doctor said she had had other patients who complained of the same thing and she had to write prescriptions for a certain generic or name brand.”


“I took Cymbalta for 3 days and thought I’d go nuts. I’m off it now and refuse to try any other drug like this. My main complaint was extreme hot flashes that estrogen wouldn’t help. I thought I’d be given Prozac, but was given Cymbalta instead. It was a rough 3 days and I stopped it last night. I am extremely tired yet cannot sleep at night. I think I was sweating even worse and my legs started feeling like I had Lyme disease again. And to be honest, within those 3 days of taking it, I didn’t contemplate suicide, but I had this crappy attitude of “who would care?”


“It took me 18 months to get off Cymbalta, with no doctor’s help. I can hardly believe that doctors have no exit strategy for this dangerous drug. I had to find this out on my own from reading and as soon as I weaned off that – about a month, the tinnitus that had occurred decreased almost completely. No doctor told me this.”


“My daughter experienced severe side effects when trying to come off Cymbalta – she had nausea, vomiting, lost peripheral vision for 24-48 hours, had shaking, etc. This was while she was doing a clinical in a hospital for college. Had she known she would have stayed on it until after clinical. I called the manufacturer and they acted like there were no such side effects from withdrawal.

“She too took apart the capsules and it took awhile, but finally she is free from that drug. I think it is a crime that the manufacturers don’t publish more detailed information concerning withdrawal. They could even make money selling a one month or two month step down prescription so individuals aren’t taking the capsules apart themselves.”


“I just turned 52 today. I went on a very low dose of Zoloft about 8 years ago to treat generalized anxiety disorder. It really did help for a long time. I recently have been pretty depressed (however I can cover it up really well) and my psychiatrist switched me to Effexor which was terrible for me. Now I’m trying Cymbalta which has not done anything either except make me feel more anxious and headachy and weird.”

“I am a registered nurse and I do not understand what the long term effects of these meds are and I am concerned. I really want to get off and see what I can do naturally for myself.”


“Getting off Cymbalta is challenging but not impossible. I, too, experienced the light-headedness, dizziness, and “brain zaps.” I described it as being able to “hear my eyes move.” It sounded like the light sabers on Star Wars. Very strange and disconcerting.

“The key is to do it very very slowly. Take the capsules apart and begin by removing 5 or 10 of the tiny balls inside. Do this for a week or so, then slowly increase the amount you remove each week or two as you can tolerate it.

“Your doctor will probably be no help at all. Mine wasn’t. He instructed me to wean off over a two to three week period and I almost lost my mind. I did it myself over about a YEAR or more. Be patient. I am completely off now and feeling GOOD.”


“I took Cymbalta for fibromyalgia and have just stopped taking it because of acute liver and GI pain- yes, pain! My liver poured bile into my gut and protested loudly! Cymbalta worked great on the fibromyalgia, but I had to stop.

“I agree that doctors don’t always realize how prescription drugs can alter your life so we must continue to advocate for ourselves.”

“I was prescribed Cymbalta ‘off-label’ to manage fibromyalgia pain When I stopped taking it because it wasn’t delivering on the promised effect of reducing my pain, I became so horribly depressed that I required hospitalization as I had become SUICIDAL!

“I will NEVER take another anti-depressant for an off-label purpose….such as Elavil/amitriptyline as a “sleep aid” which is very commonly prescribed.

“I believe it should be criminal to prescribe ANY drug for a purpose other than the one it was approved to treat.”


“I’m a 76 year old man, my libido was very low. Taking Cymbalta for peripheral neuropathy added ED as a side affect of the drug. I had a testosterone blood test; it was 1/3 what the minimum should be. So I’m taking Androgel to raise testosterone levels and it is magic. I have great libido now and am working on minimizing the Cymbalta pills. In the meantime I have been prescribed Cialis for the ED. Each pill solves the sex problem for a couple of days.”


“I have the exact symptoms as everyone else and it’s been a week. I only took Cymbalta for 2 months, but the side effects from stopping it are horrible. My doctor didn’t, nor did anyone else tell me, about any side effects and I did read the insert. Most of the time the listed side effects of meds don’t bother me, so I figured no problem.

“From reading other posts on this website and on other sites, the drug seems to affect every person the same way. I would never have taken it for my neck pain if I had known about the likelihood of side effects. The worst part for me is the dizziness, the brain zings and the sudden burst of tears for no reason. I would never take this drug again. I think the FDA needs to do longer studies on all drugs and be honest with their findings and that doctors should be honest and tell their patients what really happens when you take Cymbalta.”

Please add your own experience below in the comment section.

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  1. Annette
    rural midwest

    Cymbalta brought on homicidal ideation and planning to harm others many years ago.
    My husband helped see the dr and I was taken off of it.

  2. Anne
    United States

    I have been taking 160mg of Cymbalta for several years now. My diagnosis was major depressive disorder, severe anxiety and PTSD. 2 years ago I was diagnosed with rheumatoid arthritis and put on medication that in larger doses is used as chemotherapy.
    I have been on an extended vacation this summer and ran out of Cymbalta before I could have a refill sent to me.
    So, I am now 4ish days in to withdrawal, cold turkey.
    What I have experienced so far is HORRENDOUS! The brain zaps are the worst. Headaches that can’t be soothed, screwy vision, nausea, insomnia and constant crying… I can’t stop.
    I have decided NOT to go back onto Cymbalta because the thought of having to go through this again is inconceivable. The poison I have to take for my RA is bad enough and I am saying NO MORE!
    I’m thinking of trying a cleanse Ellen I get home just to get all of this Cymbalta residue out of my system. I have never detoxed off of anything before and after this experience I will make sure that I never will again!

  3. Pam
    Indianapolis indiana

    I was on cymbalta for four years tried to get off went cold turkey terrible side effects dizzy and weak brain fog went back on a smaller dose of a different one to get by

  4. Karen
    Auburn, ca

    I was prescribed 30mg Cymbalta for chronic back pain and the depression it has caused. I took one pill before bed last night and I have felt awful since then. Cold sweats, dry heaving, nausea, no energy, loss of appetite, sleepiness…all from the first dose. I don’t think I’m even going to stick it out and try to get through the start up period. I’ll find another natural way to deal with this. I don’t want to end up having a withdrawal issue and the unknown long term side effects scare me.

  5. Sharon

    I took Cymbalta for depression for about a year. I loved it. It did wonders for me. I took the name brand.

    Once I was changed to the generic Duloxetine, I noticed changes in me. Mainly increased anxiety. I decided to get off both since I usually only experienced the depressed moods about once every two to three months that last about a week and anxiety attacks about once every 2-3 weeks. I still had to take something for the anxiety while on Cymbalta, it was usually maybe once a month. And when I have an anxiety attack it is almost crippling and results in tears, chest pains, nausea, brain fog, and hyperventilating. I am manic depressive so the Cymbalta almost gave me that borderline manic feeling. Which everyone loves being extremely happy all the time so that was great.

    Anytime I forgot my medicine by 2 that day, I would remember I forgot because I would have an anxiety attack and the brain zaps (so glad everyone experienced them because it was hard to explain to the people around me.) I am trying to just take one pill on a daily basis and manage the rest on an as needed basis. My Levothyroxin has to be taken. Since I got put on the generic about the same time I was put on the Levothyroxin, they may have an adverse reaction to each other. I just know that I hope these withdrawal symptoms don’t last long. So tired of the brain zaps or the feeling that electrical current is coursing through me. Oh and while on Cymbalta, my libido became nonexistent.

  6. Rosa

    I have been on cymbalta for many many years, and it worked for my depression for the first while, but now I can’t get off it. The side effects are so severe that I shake uncontrollably, not just on the outside, it actually feels like my insides are shaking too. I cry in bursts, I get horrible hot flashes and overheat. I’ve tried to ween off it, but these effects become so awful I can’t take it.

    The doctors never warn you about the effects, or the withdrawals. It had really effected my every day life and I don’t know what to do.

  7. Gwen

    I have been taking 60 mg Cymbalta (currently generic brand due to insurance coverage) for approximately 3 yrs for fibromyalgia. My stupid mail order drug company took 15 days to refill my prescription. So for the last 3 days I have had to go cold turkey! I am exhausted and my eyes feel weird. Trying to work and just want to go home and sleep. Also so HOT. I tried going off Cymbalta last year by taking a pill every other day per my doctor’s advice. After approximately 1 month, the pain came back, especially in my hands. I went back to taking it every day, but now think I would like to come off of it completely.

  8. KM

    I began taking Cymbalta 4 years ago for anxiety, depression and a chronic medical condition that causes joint pain. At the time it seemed like the best option. I was very sad, I cried constantly and felt miserable. I was not pleasant to live with and my moods were destroying my family. The initial side effects were horrible. I was constantly nauseous. I thought I would never get through them but I desperately wanted to save my family. For the first couple of years it worked as long as I never missed a dose. If I did miss one within hours I would be nauseous, shaking, chills and mood swings. The insomnia after missing one was always right on time.

    The last year as I started to wean off of Cymbalta I became very depressed and had myself hospitalized in January. I was diagnosed with PTSD. I started therapy for PTSD and decided to hold off on weaning down any further.

    Recently after more therapy and more knowledge of Cymbalta, as well as more nausea issues, I decided weaning further down and getting off of Cymbalta was necessary. This time I have strange cold/hot flashes, headaches, blurry (near blind at times) vision, brain zaps, severe mood swings (driving my poor family and friends away), crying spells, hostility, nausea, nightmares, complete loss of thoughts, and as I lay here typing…the worst insomnia ever. I’m exhausted.

    Any suggestions? I’m at a standstill on weaning again because it hurts so much. I want to get off of this drug and out of this nightmare.

    Thank you for your time. I apologize for the long winded comment.

  9. lucy

    I had been on Cymbalta for approximately 4 years…..dealing with a parent with dementia and other difficult issues. After reading about the side effects, in particular, the liver damage (my blood tests showed some changes), I decided to get off.

    I read that you are not supposed to go cold turkey, but I did. I couldn’t stand the thought of counting beads in the capsules, so I just stopped. I had severe nausea, heat flashes, sweating, and periods of being chilled. I was “aggressive” and very short with everyone ( I describe myself as edgy..) But long story short, I am off. I am very happy to be off. I may have a little edginess, but I honestly feel better, fell much more clear, and have a lot more energy. It was worth it to feel really terrible for a week or so, but the withdrawal eases after about a week. It can be done. It is worth it!!!

    • Jenn

      So from reading your comments it took you a little over a couple of weeks to stop and recover from withdrawal?

      I really hope I am reading that correctly, I am on day three of no capsules after doing a month of 30mg down from 60 and 2 weeks of one every other day.

      Today is the worst day. I had to walk my youngest to a party and I honestly do not remember doing it or getting home??? But at least I had enough of an idea to not drive..

      I cannot believe how bad this drug is..

  10. Lisa

    I was prescribed Cymbalta about 6 weeks ago without a word from my Dr. that it has a difficult discontinuation syndrome. I had gone through a tough time getting off Effexor several years ago and had I knows this was a similar drug, I never would have taken it.

    Now, due to the Cymbalta my blood pressure is through the roof even while taking 3 blood pressure medications and I gained 10 lbs. in 3 weeks! I am not a thin person so the extra 10 lbs. was very upsetting. I cut my Cymbalta, with my Doctor’s instructions, from 60 to 30 mg. in a week and he told me to just stop it at that time. I took apart the capsules and poured 1/2 the beads out and took that for a week and then stopped it.

    After two days, I began to feel extremely anxious and depressed. I also had very vivid and disturbing dreams in between tossing and turning most of the night. I had to go back to 30 mgs. and he then prescribed Prozac but I’m afraid to start the decrease again because the medicine actually helps my depression and anxiety while I’m on it. It’s a catch 22, you can’t take it but you cant stop it either! Very unhappy about this situation.

  11. Jessica

    I was on cymbalta 3 months and it helped a little but I was getting pretty irritable and I decided I didn’t wanna be on it: didn’t think it would effect me bad but the first time I took it for a week, tried to get off of it and had crazy crying fit at work and was off work for a week. Went back on it two months later tried to get off it again cold turkey he again had a weird panic attack crying fit at work and was off work for 2 weeks. I was only taking one once a daily. 30mg because Canada doesn’t have a 20mg.

    Finally 3rd time I tried one day on one day off for 2 weeks like my doctor told me and I have wicked painful migraines that no amount of Advil or Tylenol can take away, psychotic thoughts about suicide like “I want to kill myself but my family would miss me and I would ruin their lives but if they died too or first they couldn’t miss me” like super crazy scary thoughts like that, super violent behaviours like telling people off when I don’t normally say anything to anyone, and telling myself if the person looking at me says anything rude to me I was going to smash his head into the stop stop glass. I’m not violent or mean hearted at alllll but I’m having a lot of angry, hateful, rage and suicide thoughts. I’m also happy one minute and angry at friends for silly things the next. Also getting hot flashes and dizziness. Rawr!!! Cymbalta sucks. Zyprexa was used to help my bpd and it gave me symptoms of schizophrenia for a year (hallucinations, thinking I had special powers, thinking everyone was out to get me, thinking my doctor could read my thoughts and I could ESP him) really went loopy on that stuff too.

  12. lr

    I have finally gone off Cymbalta for good after 3 tries. I did it over a period of approximately 3 months. I still “hear my eyes move”, which I can best describe as a “shimmer sound”. Hope this goes away soon. I mentioned to my doctor, and she had never heard of that happening.

    • Judi K.
      Brooklyn, NY

      I had been taking Cymbalta 60m per day for about 7 yrs., for depression and anxiety. I must say that for me it was very effective for both issues while taking the medication. Side effects were tolerable. I also have fibromyalgia.

      However, getting off the med is quite horrible for me. I have been weaning myself off for over a year now – and am down to 30mgs per day, minus a few of the mini-balls inside the capsules.
      Even a small decrease of 3 mini-balls causes me to feel ill – makes my fibro symptoms quite pronounced. And I seem to be prone to quickly changing moods. It takes over a week after I decrease the dose to feel decent again. It could take me another year until I am entirely off this med. Way, way too difficult to get off – this is a major drawback – and I would never take this med again knowing how incredibly hard it is for me to get off of it.

  13. Deb

    God bless you in your struggles. I know how difficult it can be. Know that God is the author of peace and life. I will be praying for you.

  14. Deb

    I agree. It did the same for me when I needed it. I have taken it once before for six years and had no side affects. I got off of it about six months ago due to a change in insurance and I thought I did not need to take it any longer.
    About two weeks ago, the depression came back full swing. I am now on the cymbalta generic twice a day 20 mg and it is working very well. It does take time for the side effects to go away at first. I had some terrible headaches, lack of appetite, and anxiousness. Those have all now subsided. I will probably be on this for the rest of my life which is okay with me as long as it works. Hope this helps others.

  15. TR

    This article and the handful of comments I read are extremely biased. I took Cymbalta for 2 years for depression and recently came off of it. I took my dose every other day for a few week, and then stopped taking it completely. I have been off of it for about 2 months now. The side affects I experienced were dizzy spells (lasting a couple of seconds) on average maybe once a day. Also got some achey-ness in my joints and back(which makes sense seeing as it also diagnoses fibromyalgia) for a couple of weeks.
    Cymbalta helped me when I was in a bad place in my life. It helped with anxiety a bit too. But I’m no advocate either, I admit my head feels a lot clearer now that I’m off of it. But it did what it was designed to do and thats to help with depression when exercise, good sleep, and a healthy diet couldn’t.

  16. T. Horton

    I was on Cymbalta for approx 3 years. Recently I was in an outpatient hosp for depression, and the doctors prescribed me a number of meds trying to figure out what worked best, while still taking Cymbalta. When I was discharged 2 months later my psychiatrist prescribed some meds which were not working for me, so he put me on pristiq and wellbutrin. He told me that he would take me off Cymbalta.
    In fact the last time I saw him about 2 to 3 weeks ago I had to remind him about taking me off. What I didn’t know if that I should have been weaned off. He just said to STOP taking it.
    After reading the post I’m not sure if even WEANING of the Cymbalta would have changed my horrible withdrawals (which is what I think I have after reading several websites on Cymbalta withdrawals). I’ve been experiencing horrible VERTIGO so much that I’m going into the hosp today as an outpatient to have an MRI on my brain and neck.
    I pray that its not serious (though I feel like dying would be my best relief right now). What I think I need to do is get my Primary Doctor, Psychiatrist and Therapist ALL on the same page in regards to my meds etc. Praying to Jehovah for direction in all of this….

    • erin

      Biased? 99% of the material out there is biased in its favor. I take Cymbalta for my MS and it works great! I feel jittery but I’m a weirdo so I enjoy the feeling. Currently I am detoxing off it, and am in the prime of hell. I have every side effect, the worst being I’m so suicidal I refuse to leave my bed because I’m obsessed with wanting to die. When I’ve had more lucid moments I’ve made it known to the people around me what is going on to take precautions. This has been hard for them to comprehend because all of this is out of character for me.

      Reading this article and other people’s experiences has been my only saving grace. So if it’s considered bias, that’s fine by me because without it I would surely be hopeless.

  17. DR

    I’ll tell you what helped me to stop being so sick with Cymbalta withdrawals: Prozac. I was desperate. I would never have considered this but I read on a forum that it helped someone else.
    Only 10 mg a day was evidently enough to help my serotonin levels, to where I lost the nausea, dizziness, and brain fog. I got them free from a friend.
    Then I got Cymbalta, finally, and started taking one 60 mg per day (half of my previous dosage). I had only taken the prozac for 3-4 days and stopped 3 days ago when I started back on cymbalta.
    WHERE IS THE CLASS ACTION LAWSUIT for the lack of a taper protocol?

  18. SV

    After taking Cymbalta for 3 months, it took approximately 8-10 weeks for all the withdrawals to subside. I would like to mention that a very recent article in our newspaper described the responsibility of the original manufacturer to add, correct and stipulate in the package insert of any drug where additional side effects, problems or withdrawals were discovered after the original trials and the first few years of distribution.
    In addition, the article stated that even after the 10 year patent runs out, thereby enabling others to manufacture and distribute the drug under a generic name; the original manufacturer was still responsible for seeing that any later problems with the drug, be made fully known and published.
    The FDA requires any generic to consist of the exact ingredients of the original drug. Therefore, any newer problems are still supposed to be the responsibility of the original manufacturer to acknowledge and inform consumers.
    The big question here is that everyone on these posts who say they’ve read the insert and absolutely no mention is made of any withdrawals, who, I ask, is supposed to hold these people responsible so that this knowledge is “out there” before people start this and other problematic drugs?
    Also, obviously the doctors are totally unaware of the problems (mine certainly was) as the drug reps fail to inform them. I understand that the moderators of this site do have a certain amount of clout when it comes to informing the FDA of problems of this nature. However, how many people must suffer these effects before it is stopped?
    I predict we will soon see lawyers on television advising consumers to call them if they have taken “Cymbalta”. This is what has happened to a lot of drugs with unacknowledged problems and includes Celebrex which my doctor strongly advised that I would not have any problems taking, a number of years ago.
    I suspect the manufacturers have already made their “millions” before the law suits start and therefore don’t mind paying out what would be a small fraction of their huge profits.

  19. Patt

    I am thankful you were not successful! God bless you! You are in my thoughts and prayers.

  20. Carrie

    I only took it on Saturday, August 23rd, and Sunday, August 24th. Once pill each day. Today is Tuesday, September 2nd….I finally feel normal again. My back pain has returned, but at least I am not dizzy, throwing up, queezy, suffering from heavy limbs, shortness of breath, and heart palpitations.
    Unfortunately, the doctor said I should feel better in a day or two and the pharmacist said no more than 4-5 days. Liars! It took a week!!!
    And, when I explained my symptoms, it was like no one believed me because they said less than 1% of people have those reactions. Well, guess what??? I am, apparently, one of those lucky ‘less than 1%!!!’ Ugh! Wish you the best of luck! If you’ve been on the medication longer, the withdrawals may be longer…just an FYI….

  21. Clara

    It took me over 3 months, from May to the end of August. However, I weaned off in very small amounts (I still had side effects, just not as severe). Each titration down would take 10-20 days to stabilize and be free of side effects, including the very last one. I am finally free of it, and after this long process do not feel any lingering side effects.

  22. Tony

    It took the better part of a month once going off the pills to fully to get over the major issues – mood swings, anger, suicidal thoughts. The serious withdrawal symptoms didn’t occur until I went below 1/4 of a pill down to nothing. I highly recommend cross tapering with another drug like Celexa (speak to your doctor or see my other post about it on this site). I wish exercise and essential oils worked for me but I’m highly skeptical about the effectiveness of holistic medicine to cure the symptoms of stopping this very dangerous drug. I wish you the very best.

  23. Mike G

    I was prescribed 60mg Cymbalta for a pain condition. I have been taking it for 10 weeks up until one week ago. The side effects have been awful. Constant sweating, feeling hot and cold at the same time!?, severe sleepiness during the day and a feeling of disconnectedness.
    I know you are not meant to go cold turkey but I missed a tablet about a week ago and felt much clearer mentally the next day so I didn’t take it the next night, or the next… it has now been a week and I do not feel too clever but probably no worse than when I was taking it every night.
    Please can someone advise if I should now just stick this cold turkey out or am I in for a whole world of trouble just around the corner? I feel anxious…

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