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Prednisone Side Effects: Deal With The Devil?

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Prednisone (and similar corticosteroids) can be a life saving drug. It saved my sanity when I developed sudden hearing loss in one ear. That was a really scary experience for someone who depends on hearing to be able to do live radio. The ear, nose and throat specialist diagnosed my deafness as "idiopathic sudden sensorineural hearing loss." In other words, he didn't have a clue what caused it. He did prescribe high doses of prednisone and within a few days my hearing returned.

Similar corticosteroids like prednisone include:

• Cortisone
• Dexamethasone
• Hydrocortisone
• Methylprednisolone
• Prednisolone

There are many conditions for which such drugs can be extremely valuable, even life saving. Here are just a few:

• Very serious allergic reactions (bad poison ivy for example)
• Anaphylactic shock (life-threatening allergic reaction)
• Brain tumors
• Inflammatory bowel disease (Crohn's disease)
• Severe asthma (usually to help control acute flare-ups)
• Severe nausea of chemotherapy
• High altitude sickness (when there is brain swelling)
• Traumatic brain injury
• Addison's disease
• Rheumatoid arthritis, lupus and polymyalgia rheumatica (PMR)
• Multiple sclerosis (MS)
• Giant cell arteritis

As useful as corticosteroids can be for a wide range of conditions, the drugs can also cause an extraordinary number of serious side effects. Some people have likened this to a deal with the devil. Even short-term use can cause problems.

The week or two that I took prednisone for my hearing loss I couldn't sleep, became incredibly irritable and hard to live with, and felt as if I had turned into someone I didn't know or like. A study in the American Journal of Psychiatry analyzed data from hundreds of thousands of European patients over an 18 year period. They discovered that people taking corticosteroids were more likely to experience neuropsychiatric symptoms including depression, suicidal thoughts (and actions), delirium, disorientation, confusion, panic and manic episodes. The authors conclude that: "Glucocorticoids [another term for corticosteroids] increase the risk of suicidal behavior and neuropsychiatric disorders. Educating patients and their families about these adverse events and increasing primary care physicians' awareness about their occurrence should facilitate early monitoring."

I can relate. I certainly felt disoriented and out of control on the relatively high dose I was taking. The trouble is that patients and their families are not always warned about such side effects. Here are some scary stories that have been reported to this website:

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"Years ago I was given prednisone in the emergency room for a severe anaphylactic reaction that affected my ability to breathe and caused massive hives. Although the treatment may have been necessary, I too had a severe psychotic reaction and when I finally went to my own doctor and had blood tests, my blood chemistry was all over the map. I had to continue the tapered dose till I was done but I wish someone had warned me of possible side effects so at least I wouldn't think I was totally crazy.

"I questioned my ability to drive, slept constantly, and was quite volatile. I had to take a day off from work. Knowledge is power! People should be warned about possible side effects so they have the information should side effects occur." AC

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"I was on 20mg twice a day of prednisone for a sinus infection. Had I known anything about this horrible drug I would have never taken the meds and let my sinus infection clear up on its own. That would have been better than these side effects.

"I was not told to taper the dose, so I took as prescribed 20mg twice daily for 7 days. The day after stopping my whole body hurt to the touch, as if I was black and blue all over. I was swollen, red and had a lump on my neck, not to mention being very disoriented. I went back to the doctor and he insisted this had nothing to do with the drug.

"I checked myself into the ER where they put an IV drip with benadryl and the like. I was discharged that day. No change. Next day, didn't hurt to the touch anymore. New side effect - rash from head to toe and severe indigestion. Following day, rash subsiding, indigestion getting better. Still feeling a bit loopy, but I am told by next week I should be back to myself again.

"I am warning everyone i know not to ever take a steroid unless your life is in danger. It is a very scary feeling - all for a sinus infection." AMS

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"I'm having Prednisone side effects. My doctor prescribed this drug last Thursday. She prescribed 20mg twice daily for five days. I was sleepless for three days in row. On day 4 after a short nap I awake feeling so nervous. I am crying, my hands are shaking, and my heart is beating so hard. These are awful feelings.

"My doctor told me I will feel that way for about nine days. She didn't show any care about me. She also said I can go back to work (and drive a long way) the next day. But the way I was and am feeling I'm not daring to drive even one block.

"I do not understand why she prescribed that medicine, without any warning, for a small allergy I had. I mean the medicine was worse than my illness." ELY

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"My wife had sleepness nights when on prednisone and the doctor said that she might do some odd things that she normally wouldn't do. He was right. One night she got up and tore down the wall paper in our bathroom :-) We still get a laugh over this one."
Bob K.

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"I am experiencing high blood pressure, agoraphobia, panic attacks, light headedness, confusion, weakness, intolerance to heat, IBS, shaking, etc. These side effects all started the day I stopped the drug. It has been 7 days with not much improvement. I was hospitalized for 3 days. I pray I do not EVER have to take prednisone again... EVER.

"I am hoping I get past this. My quality of life stinks. I took 30mg 1 day 20mg 2 days and 1 mg 2 days. Absolutely HATE this." SKF

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These are just some of the messages that have been posted to our website. Feel free to add your story or comment below. We find it astonishing that some prescribers do not warn patients about the possibility of psychological side effects brought on by prednisone and friends. Even a short-course of high-dose steroid can precipitate symptoms. And not warning about gradual tapering borders on bad medicine. To protect yourself and your loved ones from such medical mistakes we suggest our latest book, Top Screw-ups Doctors Make and How to Avoid Them.

We want to emphasize that corticosteroids can be very valuable. Some people must take them for the rest of their lives because of a very serious or life-threatening condition. And NO ONE should ever stop taking a drug like prednisone suddenly. It must be phased off gradually under medical supervision.

Here are some other side effects associated with corticosteroids.

• Fluid retention, edema
• Insomnia
• Irritability, nervousness, mood swings, mania, depression, psychosis
• Disorientation, confusion
• Hypertension
• Loss of potassium
• Headache
• Dizziness, vertigo
• Muscle weakness
• Blood sugar elevation (diabetes)
• Irregular menstrual cycles
• Swollen face
• Hair growth (including on the face)
• Itching, rash, hives
• Increased susceptibility to infection
• Weakened bones (osteopenia, osteoporosis)
• Tendon rupture
• Glaucoma
• Cataracts
• Ulcers

The higher the dose and the longer someone takes a drug like prednisone the more likely there will be side effects. Make sure your physician is monitoring things like potassium, blood sugar, bone density and psychological well being. And never stop a corticosteroid suddenly!

Joe Graedon, for The Soapbox blog on The People's Pharmacy

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High doses of corticosteroids are dangerous, and very often unnecessary at that dosage level. Any physician prescribing these type of drugs should first read the book "Safe Uses of Cortisone" by Dr. William McKesson Jeffries. Jeffries was a pioneer in the field of cortisone use in humans.

Although I have bipolar disorder, my doctor prescribed Prednisone for an ear problem. What followed was a full-blown manic episode which lasted two months despite treatment. It also led indirectly into lithium toxicity, which wasn't resolved for several weeks. I basically lost three months of useful existence. Now I advise doctors' offices that I am allergic to Prednisone so they flag my chart. In checking information later, I found that bipolar patients should never be prescribed Prednisone or other oral steroids.

I took Prednisone last year for a severe allergic reaction. I was prescribed a pack with a declining dose. Knowing I tend to over-react to medications anyway, I decided to take 1/2 the dose prescribed each day. Even with that reduced dose, I did not sleep that week, lost all ability to digest food, and five days into the meds, I honestly thought I was going to die that night. I said my final goodbyes to my husband, declined his offer to take me to the emergency room, and simply assumed I would not awake the next day.

Since that time, I have declared myself allergic to that drug so it will not be given to me again. I do understand what a life-saver it is, and it certainly did stop the allergic reaction. But I do hope, "never again."

I'd like to see the comments on this.

I was prescribed Prednisone at the onset of my MS. No info re possible side effects was given. Two dentists and an oral surgeon have now told me that my tooth loss and jaw bone deterioration are directly related to taking this drug. About three years ago, my teeth suddenly started breaking off and becoming infected. I've now had all my teeth extracted, and have had skin grafting for the tissue loss. I would never take this drug again, and have told others about my situation.

I absolutely hated taking this medicine...

I took this last year for hives (mold in the basement) After 9 days on tapered dose I still had the hives but had the cleanest house ever! I am retired so I did not have to leave the house.

I use Prednisolone as eye drops since having my retina detach. Could there be the same side effects from drops?

Prednisone was prescribed for me to counteract a toxic reaction to potassium iodide which was prescribed for erythema nodosum. I didn't sleep at all for two nights, had hallucinations right out of hell, had fever, chills, lack of bowel control, strange feeling in my head and became extremely weak. Weeks later I had tendon problems in my ankles, but fortunately, they did not rupture. I was not informed of possible side effects by my doctor. Wouldn't recommend this drug to anyone. Now, I don't have a prescripion filled until I've checked the internet for reactions others have experienced. To be sure I was in serious danger from the toxic condition, but I would not want to take Prednisone again for any reason.

There are a few of us out there that MUST take this drug because it is the only course of treatment for ABPA (allergic bronchopulmonary aspergillosis) I was on 50 mg. to start with because of 4 years of misdiagnosis until I finally found a pulmonary doctor who recognized my symptoms immediately & did the necessary tests that verified the disease. My IGe levels are monitored monthly & determine whether I can go up or down on Prednisone dosage.

Right now I'm living successfully on 5 mg. It is a love/hate relationship that I have with Prednisone: it cleared my 4 year cough in 2 weeks, have only had 1 relapse so far & am grateful for that. But: I've gained 10 lbs., must watch very closely what I eat so as not to gain more, have the tummy lump,the back fat & round face to show for other side effects. This drug & I will be partners for life or until someone finds a cure for ABPA.

About 12 years ago I wasn't breathing well and the doctor prescribed about 7 to 10 days of Prednisone and was sure to tell me to gradually ease off of it which I did.
It did give me a great new feeling of energy and I could breathe.

However I gained about 50 lbs in 3 days. My hand fed my face non-stop all the days long. I'm still trying to loose that extra weight. I have told doctors since then that I do not EVER want Prednisone unless it is all that will save my life.

I think I will also say I am 'allergic' to it for good measure.

hello.. I was put on Prednisone 12 day taper 9 days ago for what my doctor thought to be fatty gout in finger. I had taken the methprednisone in the past with no side effects so he said I should not have problems. I have a very important job and cannot afford to be off work. I began my prednisone that day at 40 mg by the time I got to day 4 where I just took 30 I awoke after just one hour sleep soaking wet and shaking like I had the flu. I could not fall asleep after that. The nausea was unrelenting and was burning up all over.

The next day I could not work.. I called the doc and he told me to just take 20 mg that day and then just 10 mg the next and stop. I did that. Today is jut 2 days after I stopped and I have exhaustion and fever and nausea. I hope this passes. My gout or whatever it is, is back with a vengeance and I feel like crying. I heard horror stories about the drug causing side effects for a long time but I was only on 6 days. Do you think it will be out of my system soon? This is horrible and can't function like this all because of a swollen joint.

Hi, I had a severe reaction to medication that I was given to treat a parasite - Blastocystis Hominis - I ballooned, looking 9 months pregnant, and my weight sky rocketed in a matter of days - my GP then prescribed Prednisone to counter act the reaction to the meds to treat the parasite - But I reacted to the Prednisone - I should note that the GP wrote the incorrect dosage down and I took too many pills resulting in an overdose of the prednisone - I was informed by the doctors at the emergency hospital that this would not cause any side effects and to not take anymore pills.

Since that time (almost 2 years) I have had chronic fatigue, weight gain (almost 20kilos), fluid retention and exhaustion. I was sent to an endocrinologist who informed me that Prednisone can cause insulin resistance hence my inability to lose weight & feel normal. The endocrinologist put me on Metformin only my fluid retention was shocking - I could barely walk so I took myself off it - I can honestly say that Prednisone is bad news.

It only made the reaction that I was having to the parasite meds much worse -I want to know how long these meds stay in one's system - Can they linger in the kidneys or cause liver or other organ damage?

I was prescribed prednisone couple months ago for bulging disc in back and took it for for 5 days 40 mgs twice a day with no tapering no probs. A month and a half later was having back problems again so he said it should be ok to take the prednisone again same dosage. I took it and the last day I was on it I started getting rapid heart rate, then next few weeks got sick, no appetite, diarrhea,and my skin will feel like its on fire off and on ear ringing, head tingling, burning on side of head, so I went back to docs office and found out I had lost over 13 pounds since I took the prednisone again, doc couldn't figure anything out so he did all kinds of test and everything came back normal.

So he assumed it was cause he put me back on prednisone too fast and didn't taper me off so I'm on 18 day tapering and have 3 days left. I still have the rapid heart rate and and ear ringing came back on one side and causing vision problems off and on. I will NEVER take this drug again!! Is there anyone else having these symptoms like mine? Any feedback would be appreciated, i feel like I'm goin out of my dang mind!!!!

Hi! Wish I had the answers for so many of you. I need answers, too, and turned to our heavenly Father for those, but like the story of Paul with the thorn in his side (whatever that symbolized), the Lord answered our prayers by keeping me alive. Prednisone saved my life when my constant asthmatic attacks (episodes) took its toll on my immune system. Had to stop work March 30th - just like that if I wanted to live long enough to enjoy retirement. Planned on working until 75 or 80 as I've taught middle school for 42 years and love the kids and my Sunday School kids. The doctor said to get away from those carrying the germs that were making me so sick. Since then the asthma part is great - good peak flow, feel better generally, and thank God for that and my pulmonary specialist - she saved my life with God's help!
Now here are my adverse prednisone reactions: swollen feet, painful feet, edema, sudden and continual pain in right upper arm, then lower arm; repeated on left side, memory confusion, then with swollen hard to walk on feet my toe next to the big toe on my left foot which was also swollen and did not even look like a toe started oozing blood, pus, and was an awful mess. My primary care gave me antibiotics to help clear up the infection. It pretty much healed with this weird wart like growth on the end of it. Soaked it in epsom salts; it fell off; then came back and is still there - dark, sore, cannot cut it off or file it down - too painful. Now my right foot feels like it's fractured or at least badly sprained. All the blood tests came back normal. Supposed to have a MRI to check for spinal stenosis as my primary care doctor says it is not an adverse prednisone reaction.
I've searched spinal stenosis and don't have the symptoms as far as pain is supposed to be when you are up walking around and disappear at rest. My pain and numbness come when I'm sleeping, and are greatly helped by doing Lesley Sansone workouts! FURTHERMORE, my pain and numbness with the total difficulty of actually feeling my feet to even walk around taking me 15 minutes in the night to get to the bathroom is my biggest complaint now. Any suggestions from any of you who have been on prednisone?
This last 21 taper of prednisone was started May 13th, Mother's Day, when I came down with a horrible flu/asthma episode and slept in my Husband's recliner for 10 days and had him worried sick after he had a serious seizure (I thought I was a widow for sure.). But praise God he is doing wonderfully well and I'm doing well in the asthma department, but terrible in the after effect of prednisone and wonder just how long it will last???

Terry and Joe,

Thanks for all your work over the years. I read that you have personally had sudden hearing loss and how is it going. On August 15th 2012 I woke up not hearing out of my right ear. I went to my primary care and was told I had a blocked Eustachian tube and was told to chew gum and give it time. Two days later it was no better and I left a message with the doctor's nurse and she called back saying they were calling in a prescription for 50 mg prednisone to reduce inflammation (I assume for the middle ear or Eustachian tube) I tried it and my head went crazy. It was too much and I stopped it. I called the next day and said it was too strong and they said "call an ENT specialist" and gave me a couple of names. I called them and it was nearly a week until I could get an appointment

The specialist took one look, did a pressure test and hearing test and said sudden hearing loss and he sees about one a week. He said there is about a three week window if you catch it in time. It had already been two weeks. He gave me a prescription for prednisone and this time a taper up to 40mg and hold that for a week and then taper down. I read later that it is best "cured" the soon after the onset you catch it, the better.Thanks to my primary care physician I may have permanent hearing loss, bummer.

Prednisone is the bad boy of medicine but they say it is the best thing for this malady. I would not give this drug to my worst enemy. I feel like I have two heads and neither one of them can hear out the right side at all. I think it is getting worse if anything. I am nervous, anxious, blood pressure is up (ENT specialist said it doesn't raise blood pressure, well it does too!)It has wrecked my life. I can't do simple tasks without forgetting basic things and I get confused going to places I know like the back of my hand. I hope and pray this stuff works, being suddenly deaf is more than depressing, it is devastating.

PEOPLE'S PHARMACY RESPONSE: Prednisone often does work for this kind of sudden hearing loss. When it works, it is worth putting up with the side effects. As you say, they can be awful!

I took prednisone for 8 months. After being tapered off it, it took about a month or two before I felt normal again. Don't worry the side effects will clear up...it just takes time.

HI.. I am facing the same problems with my Mother. She has crohn's disease and She has been taking prednisone for almost 30 years. And I can see now that it is really effecting her emotionally very much. I think depression is taking control over her, but I really don't know for sure if that's all due to prednisone or other things like getting old??

Anyways I am desperate and I don't know what to do anymore, as I always try to get her to see a doctor or a consultant she keeps telling the is no use and they are gonna say the same things that doctors have been telling me all these years. I feel useless but I never stop trying to make her feel better and make her happy, however it hasn't been beneficial lately.
I hope if anyone can give me a tip or a piece of information that would help me, I would be soo grateful.
Thanks

Thanks so much, Chris, for your comment. It is reassuring to know that there will be an end to this; and the side effects are lessening for which I am truly relieved. The last two days my back started hurting and a hot rice "sock" that my daughter made us for Christmas one year, helps relieve the pain. Just wondered if it could be a reaction this long after taking prednisone. On one sight I found a year as a possible duration and on another someone claimed that it could last as long as 6 years. Let's hope not. Again thanks!

I am 11lb female was prescribed 30mg/day for systemic itchy skin rash. After just 2 dosages I had: severe irregular heartbeats- I was sure I would die; severe stomach pain, severe lower back pain where I could not walk straight;heavy mid-period menstrual bleeding. It had no effect on the rash, despite doctor's assurance that it will be cleared in 24hr. Stomach and lower back pain lasted for close 3 weeks.

My doctor prescribed prednisone for Lupus and now I am worse than I was before. I was anxious, unable to sleep and my mind was foggy until I stopped taking this poison.
I am on Plaquenal now and I feel like crap. The doctors do not care or even listen to you. I went to the Rhumetologist and had to be examined by a med student which took forever and when the doctor finally came into the office it was like they talked to each other like I was not even there. The med student did not advise the doctor of everything I said so I feel I was not properly looked after just treated like a lab rat.

My doctor prescribed azithromycin 250mg tablets 6-pak on Sept. 5 2012 for bronchitis still not feeling the best went back to the doctor Sept. 25 now I have a severe sinus infection so an additional 10 days prescibed to take 25 mg of prednisone and everything has been out of wack like so confused.

Oct 5th my last day and I am so glad, I have been eating constantly breaking out in sweats and they come more often especially when I am out as work in the public eye. I stay confused, can't function, dizzy off balance, insomnia, chest pains for at least two nights I felt if I was having a heart attack got up and took a low dose 81mg aspirin. One night my legs kept having these spasms in my thighs, I'm like God what is going on.

Although I go to work I can't stay my thoughts were just running all over the place, I felt like something was making me sick in the building and causing me not to be able to think straight, so in order not to lead on to the other employees I just leave for fear that I was having a nervous breakdown or worse is she crazy. My last dose of the prednisone was Oct 5, still not sleeping, start to try and explain to my husband and he says stop saying it so that it doesn't affect you, pray, I know that as to make me feel like it's just a faze or something; that's when I got up and decided to check this thing out at first I thought I don't feel like taking the time out to type out how this has affected me then I remembered it's just like the gospel if you don't tell about it won't work so in that essence this my testimony to this medicine in hopes that someone else can be better informed and hope that it does not take a long term affect on me. In conclusion, I will not take this medicine.

I was on extremely high doses of prednisone for 6 months to treat kidney disease. I alternated between a chemo drug and the steroid. I took 120 mg. a day, with 3 days of an IV push every other month. I had to quit my job, I had hallucinations like you would not believe! I was shaking so much it was more like a seizure! I developed weird obsessions while I was on them. I could not drive or hardly walk through a store. The side effects were overwhelming. But it did put my kidney disease into remission and save me from transplant. I would not want to repeat the experience. I do have a lot of bone joint, teeth issues now because of the high steroid doses. It is a nasty drug, but effective

I took prednisone for eyes and had terrible muscle weakness. It went away for 5 days and came back again. I am still having weakness a month later. I am not sure if it is related to prednisone eye med. The 5 day thing started when I ate some food that I had been avoiding on a health diet. it sounds crazy, but I do not know if it was prednisone or food, but it is awful.
Did you have any negative side effects from prednisone for eyes?

I was given Prednisone after an allergic reaction to Zithromax. While taking the Prednisone, I developed a racing heart and anxiety all over my body. It was like someone had plugged me into an electrical outlet. I only took the Prednisone for about two weeks but the anxiety lasted for 19 months. I had to see a psychiatrist and take large doses of Klonopin to try to keep the anxiety under control.

We tried anti-depressants with anxiety properties as well. However, it took my body 19 months to accept Desiprimine. This is the only AD that my body would accept during this time. All the others that we tried just ramped me up more. My life changed drastically. I went from being a normal 48 year old woman to an invalid. My job suffered and my life has totally changed. This was the scariest experience of my life. I thought of suicide many times. The doctor couldn't tell when or if the anxiety would lessen with time or go away. It has just finally started subsiding after 19 months. I found out after the fact that people who suffer from depression are more likely to experience side effects when taking steroids. I will never take this drug again unless it's the only way to save my life!!

I have had Lupus for 40 years and feeling like a lab rat is just part of the disease because of the way it is different for each person and even the symptoms and the way it shows up change often. It is a very hard disease to diagnose and treat because of this. The best thing that you can do for yourself is to stay as positive as you can, find a doctor that will listen to you and respects your opinion and most importantly rely on the strength of the Lord and others.

Doctors know medicine but you know your body best. I can also tell you that my Lupus has had many manifestations over the years and at the beginning they tried Prednisone and it just didn't work. Later in life and with a different symptom it now works. Even though the side effects can be horrible (I cant sleep and have had bone deterioration, cataracts in both eyes, and dry mouth which has caused oral problems) it has been my only saving grace in some moments of crisis when I had meningitis and brain tumors. So the moral is that with this ever changing disease, you may also have drugs that change how they work too. Good luck with your search for a new physician.

I have Lupus and have had problems with my eyes. I get Uveitis frequently sometimes when I have let this go too long I have actually had blisters on my Iris. I was on these Pred Forte drops and while they work well for this I ended up with cataracts in both eyes which was directly because of this drug. I have had cataract surgery and everything is good now.

In June of 2011 I was given prednisone because my leg mysteriously went numb from my knee on down. I was told I "could" have had a pinched nerve. The ER doc gave me 20mg to take twice a day for 5 days. I was told nothing about tapering or anything. On day 1 of taking the meds I immediately went into a zombie state. I didn't know what day it was, what I did the day before I was completely out of touch with reality. I called the ER doc which they wouldn't let me talk to, my own doc and the pharmacy. They all told me it couldn't be the prednisone. Silly me knowing that it was, pushed my self telling my self I only had 4 days left to take it.

Even my co-workers said that I was acting weird. I woke up on day 7, 2 days after finishing my dose to a massive, massive migraine. It was so severe it woke me up out of my sleep. It took everything I had to focus enough to drive my self safely to the ER. The pain was so bad I literally felt I was on my way to meet my maker and that my affairs were not complete, my kids were so small and all I could do was cry, squirm and clinch the bed rails in pain. I was given a cat scan and put on 3 different pain meds to stop the pain. The docs in the ER said again it couldn't be the prednisone and that I just suffered a mid life migraine. I argued with them until I was tired of talking. I never had any migraines in my life and since that day I haven't had one.

Since that episode I now suffer massive memory loss. I can't cook by myself because I forget as soon as I walk away. I can't remember what I wore or did the day before. I can't keep up with anything in the house. I walk out of the room and always forget what I was doing. I get lost in all my sentences. I can't remember times or appointments. I forget simple math and how to spell simple words. I am even struggling now to type this. I am 28 years old who has graduated with a 4.0 in the top 10 of my class.

I try to tell my self it will get better. It has been a year and a half and I am getting worse. I can't remember anything past a 2 minute mark of doing, saying or hearing it. I hear a weird swoosh sound of my heart beat in my ears and each time I have blood drawn I can hear the valve release of my blood going through the needle. I am ruined. I have been turned into a near vegetable just from a 5 day dose. I cry everyday because I know eventually I will need a live-in assistant or family member because I won't be able to care for me or my children.

been on pred for four weeks and now tapering down. first time had a short burst for three days ended up with asthma attack! so had to have more prescribed. now on 20mg a day until tomorrow then 10mg - but today I have just been in bed with upset stomach, temperature and flu like feeling. was supposed to be back at work so had to call in again (after 3 weeks off already). looking online I believe it is the side effects of tapering. fortunately I have hosp appoint next week (finally been referred). but I feel absolutely bloody lousy. reading others thoughts has been helpful. I just want to feel like me again. not gained weight as no appetite much but that's not good either. I feel all over the show and very emotional. thanks for listening

I was put on a daily dose of 120 mg of Prednisone for "inflammation" from sudden hearing loss in one ear, and took this for ten days, starting a couple days after waking up with the total deafness. About six weeks after completing this course, I am still have complete deafness, with the muscles that open and close the Eustachian tube remaining immobilized from extensive nerve damage.

Far from being a miraculous cure, while taking Prednisone I thought the extent of its damage would be getting an ulcer, with nausea, gagging, vomiting and dry heaves (it was prescribed with Prilosec, which didn't prevent this outcome - that side effect seems resolved now).

But afterwards, I began to notice skin wrinkling (legs, trunk, arms, etc.), along with sagging from loss of muscle tone (and probably collagen) - this 'skin thinning' and tissue degeneration seems to be getting worse daily. There has also been the constant 'taste' of the drug in my mouth between meals, and my teeth becoming sensitive to cold (especially the front teeth). Ankle tendon weakness has also been an issue. Apparently Prednisone suppresses the immune system, and can cause hormonal problems, particularly with adrenals, as well as weaken bones and joints.

While anyone losing their hearing may be desperate enough to risk these adverse effects, they should be made aware of how grave the negative aspects can be, and that successful outcomes are for the statistically lucky.

A week ago I was put on a low dose of prednisone. 20mg once daily. Beside feeling disconnected, I also developed an irregular heart beat, a ringing in my ears every so often and a vague feeling of diminished hearing, and a slight tinnitus, weird noises in my ears might be more specific. I don't see hearing issues as one of prednisone's side effects but it seems odd this came on within 24-36 hours after starting my treatment. Is it possible prednisone is causing this? On a side-note I like to say this is a horrible drug, unless I'm on the verge of a catastrophic bodily failure of some kind I'll never take this stuff again. I talked to my rheumotologist today and I'm being reduced from 20 mg to 10 mg once daily, maybe this will help.

I have been on prednisone for11 days, 30, 20, 10, 5mg. I have never felt better, not in years. I have to say, now that I'm on 5mg., I'm back to being stressed out and extremely irritable. While I was on the higher dosage, I felt like I hadn't felt in years, me! I've thought a lot lately about where I went to, I was a happy, joyful person. I wondered what happened to me, then I developed another respiratory and sinus infection and hence, the prednisone.

I had forgotten what it was like to feel like me, for whatever reason, the prednisone brought that back. I was happy, not grumpy, tired, short-tempered and miserable. I had totally forgotten what it felt like to be me. Now that I'm on the 5mg. dose, I don't feel that way. I want to feel like me again.

It was so wonderful to finally have energy and happiness again. My question is, what do I do to get that back? Can I take 10mg. of prednisone without harmful side effects and if not, what could be the cause of me finally feeling like myself again? Are there any test that can be done to determine the reason for this? Could I have an adrenal gland problem? Help???

I have been on prednisone off and on for theree years. I have Ulcerative Colitis and after each hospital stay (4 in the last 3 years) I start on 40mg. It does help my UC but the side effects are terrible.... moon face, stomach swelling, weakness in legs, dizziness, total inability to function normally.

I was given the pill because of inflammation, using for past 8 years now I can feel that it weakened my bones and I can't live without it. can anyone help me, it really helps but destroying my life slowly.

Hi June, I'm a nurse, not an MD, but is it possible you could have been suffering from a chronic depression? Then when you took the prednisone it gave you a temporary relief. A side effect of prednisone can be a euphoria like feeling. Maybe you just need an anti-depressant. You can not stay on prednisone indefinitely..it has pretty nasty side effects. Good luck to you. JK

PEOPLE'S PHARMACY RESPONSE: Side effects of prednisone include headache, insomnia, mood swings, nervousness, fluid retention, dizziness, high blood pressure, high blood sugar, red spots on the skin (including the face), glaucoma, menstrual problems, poor wound healing, hives, and low potassium. Long term effects include cataracts, infection, impaired immunity and Cushing syndrome. This is not something you want to sign up except strictly as needed.

This is the scariest drug ever! I was put on it for 3 weeks for a terrible case of poison ivy. I tapered off like I was told and that was 7 days ago and I feel like I am getting worse everyday. I am shaking so bad I can barely work. My vision is messed up, and I feel confused and am having trouble driving. Today I started throwing up and have the chills. My face is so swollen I am embarrassed to go anywhere. I feel like I am having a heart attack.

I checked on every website looking for a way to stop this, but I haven't found an answer. I will never take this again. I don't wish this hell on anyone!

Had a nasty choking cough and virus for 4 weeks to start with I was given amoxicillin and a nasal spray as sinuses were infected they didn't work at all, on returning back to the doctor was prescribed 30mg prednisolone 6 5mg tablets per day for two weeks and I've never felt so rough in my life no sleep at all for the first 4 days then averaging about 2 hours per night after, also feeling very clammy, irritable, head feeling light one minute then heavy the next, feeling very hungry at silly times of the night even after normal meals, anxious and disorientated.

I am currently also taking 20mg oxycontin and paracetamol for spondelosis in my lower back as waiting on surgery, also recently been diagnosed with syringomyelia in upper area of back to be honest I'm 42 years of age and don't know whether my doctor is trying to play russian roulette or to actually sort my medical situation out. I've been waiting 4 years for surgery which is crazy.

I would recommend alternative treatment rather than prednisolone myself if available as its very unpleasant and even though I have finished the 2 week course have no real clue as to how long these side effects will last or how to improve side effects but thankfully haven't ended up with a moon face.

all i can say is prednisone is awfull even for animals. I was given prednisone for my poor dog who has a rash on his snout that wont go away and he keeps scratching it making it bleed. and since he started on this he sleeps for two minuts tops before twitching awake. He cant walk on one of his legs like its sprained which it is not he has always had a little limp in that let but this prednisone made him pretty well imobile. this is just a awful drug for animals or humans to take. I sure hope these side effects dont last as I want my best friend back ive had for 14yrs now..

I was just put on a Prednisone "pack". 60mg for 2 days, 40mg for 2 days, and then 20mg for two days after a SEVERE allergic reaction to something at the hospital I am employed. I ended up having to use my Epi-Pen it was so bad. This morning I woke up and my face is super swollen and my ears are ringing. My face is bright red and I have a super upset stomach. (I'm also 9 1/2 weeks post-op from gastric bypass.) But all this considered, it's better than than having another allergic reaction and having to do another dose of Epinephrine. I count myself blessed for now. Hopefully the swelling will go down and I'll get some energy back soon. c:

Hey guys, I just got done reading all of these comments, they have put me at ease. I had bronchitis a couple of days ago and was prescribed predisone 20 mg, tapering doses. I was sooo afraid I was going to die, I have racing heart rates and near fainting spells, coupled with diarrhea and incessant hunger, I thought the bronchitis was causing my heart to race and dizzy spacey feelings that lasted for hours, but after searching this and other comment boards I have concluded that predisone is the problem, I wish had known this before and I wouldn't have wasted my money on this drug, it may have helped me get over bronchitis but at a very severe cost. I didn't know it affected so much, today I took the remainder of the pills and fell asleep and woke up thinking I was having a heart attack, racing pulse, I was so dizzy and afraid, thinking back every time I took predisone I had horrible racing pulse and near fainting spells, I just blamed this on the bronchitis at the time but now I know better, I hope all you guys feel better and me too. I wished the doctor had warned me but he didn't at all

I have IPF, diagnosed about 8 years ago. I was never allergic to any medicines in the past. About 7 or 8 years ago, I was put on Celebrex, an NSAID and had a terrible allergic reaction to it. I have been having moderate to severe joint pain for several months. A few months ago, we tried Lyrica. I had the same allergic reaction as Celebrex. My doctor put me on a very, very low dose of prednisone (5mg once a day). Within 3 days I was miserable. I had severe abdominal cramping and terrible nausea and I felt like my skin was crawling off of me. I stopped taking the pred immediately and within 3 or so days, all the symptoms went away. I still have the moderate to severe joint pain and take Vicodin for that and I will steer very clear of prednisone in the future.

I was put on prednisone for 3days 10mg. 3x daily no tapering, for fliud, due
to osteoarthritis, only 3 days because of numerous medication allergies, now
5 days later,not feeling right, lot of nervousness. Can anyone respond to this.

I devloped debilitaing pain that went on for weeks, only Vicodin seemed to help. It hurt to do anything, sit, walk, even turn a key in the lock. Then I ran into someone who said they had Polymyalgia Rumatica which comes on suddenly, for no reason, usually women over 70 (I am 72) and the only treatment is Prednisone. I researched it on the Internet and yes, all my symptoms matched. I printed it out and took it to my doctor, (who acted like he discovered it) and prescribed 15mg of Pred and in one day the pain was gone!!

In 2 days nothing hurt and that was 4 months ago. I gradually got down to 10Mg but my blood sugar shot up to 225, so now he has me on meds for that, and for cholesterol, and Prozak and Lamotrigine (depression and anxiety, I guess I am bi-polar??) and Vesacare for my weak bladder.
So now I feel REALLY good, nothing hurts but I am a walking pharmacy and that scares me. I am also hooked on Vicodin (500 mg) a day (I don't really need it, but like how I feel on it) and Ambien (10mg) which I have taken for years.

So here I am a 72 year old lady and a drug addict of sorts. I have considered stopping everything (gradually), but I am so afraid the pain might come back, it was so bad. My fear really is what is this all doing to me. I am not afraid to lose a few years to gain some good years, but it's really scary. My doctor is really a pill pusher, I don't think he has a clear picture of all these drugs and what they do, but he is willing to work with me at least, I do all the research. Any comments?

I was started on predosine 10mg once a day for severe RA pain. I am diabetic, so we weren't for sure how this was going to effect the sugars. I called the the doctor back as asked and she upped the dose to 20 mg., saying it was too soon to tell anything. Now, I am having terrible indigestion, IBS, and depression so bad I haven't been out of bed in 3 days except to go to bathroom.

I looked up side effects of the medication and these are some, so I will quit taking the medicine and make my next dr. appt. What aggravates me is that why do Drs think what works for one person works for everyone?

Latoya...could your 'migraine' readlly have been a stroke? My mum had several strokes over a few years before she was diagnosed. It could be that the prednisone caused a stroke that first night? Hope you get well from this.

On November 26, 2012.. I went to my primary doctor for complaint of upper back and shoulder pain.. I was prescribed prednisone for 12 days.. I started with 60mg for 4 days, and started tapering dose on 5th day to 40mg... well half way through 5th day.. I began feeling really bad.. I was dizzy, diarrhea, sensitive to heat, just an overall ill feeling.

I called my doctor to let them of the symptoms I was experiencing, I was told by nurse to just stop taking medication immediately. After stopping meds pain came back with a vengeance. Couldn't sleep, anxiety, tremors, off balance, head feels like it's in fog, blurred vision, and a number of other symptoms. It's been about 2 weeks since I stopped the prednisone and I am still not feeling normal..

My doctor says I must have had a bad reaction to the prednisone (you think!) took lab work everything seems to be normal.. did anyone ever have these side effects from taking prednisone? I need some help because it's affecting my life negatively... I've had to miss days from work due to be off balance to the point I could not stand for a long period, I cannot drive or just do any shopping because of the imbalance problem and the bad anxiety attacks I am having... please help... I need answers.

My mother was prescribed 10mg for sudden onset of polymyalgia rheumatica (PMR) and it worked overnight like a charm. However, she was not given much information about this drug. Even now, as she tapers off it, she asks what is the harm in just stopping it altogether. If I were not here reading her these stories, she would have no clue the seriousness of prednisone or the side effects. Next up, acupuncture.

I wish what you said were true. For people like me if we took your advice we could die. I have secondary exogenous adrenal sufficiency that went undiagnosed and flat out ignored for a year. One Dr tried telling me I was depressed. I was slowly dying! I am now on hydrocortisone therapy and praying I will be well again. My kids need me. I want to be healthy again. My acth and cortisol were nearly flat lined. I went to the er 17 times not to forget mention regular Dr appts. The reaction I had is rare and they ignored the obvious signs and neglected to follow standard protocol.

I hope you and everyone posting here is well and doing ok. I'm struggling. I have liver damage from vancomycin and even though the good half of my liver is in great condition the endo won't allow me past 15mg hydrocortisone even though I have lung infection and taking ampicillin. This sucks! I told the er that I'm allergic to prednisone and they gave me high dose no taper anyway!

I was prescribed Prednisolone 60mg daily for ulcerative colitis about 25 years ago. The affect it had on me was unforgettable. Not only did I double my weight within a matter of a couple of weeks but I was almost paranoid and completely out of my tree. I have never experienced anything like this in my life. Despite relating this to my rheumatologist, he insisted on putting me on a low dose (7.5mg) which I tolerated. However, I then started using sub-cutaneous Methotrexate and had an adverse reaction which caused a condition similar to polymyalgia.

The Methotrexate was stopped and the steroids increased to 10mg daily. Within 48 hours I started to get chaotic. I was unable to concentrate and I couldn't complete the simplest task without getting in a muddle. I put up with this for 2 weeks but it was getting worse so I went to see my GP. He didn't need to be told what was happening - it was obvious. When he read the consultants letter it would seem that he had every intention of increasing the Prednisolone by another 5mg. Thankfully my GP reduced the dose to 7.5mg and is writing to the consultant to tell him that this needs to be reduced over the next few weeks until I am off it completely.

I am weepy, tired and have the most awful vertigo, which may be coincidental. My blood pressure is going through the roof and I think my glucose level is also rising. Believe me, the very small improvement I have had with the rheumatoid arthritis is just not worth taking this dreadful medication. I want to feel normal again.

Howdy CRB,

I completely can relate. I had to be treated for an injury with prednisone and had very similar side effects. I'll be honest with you and say that I had been administered that same high dose 3 months ago for about 2 weeks and I am still suffering from side effects, but I am able to function in my work environment. The panic attacks are quite rare now. I can see improvement and am told by a more informed doctor than the physician who originally prescribed the drug that side effects can persist from a few days to even 6 months depending on how the prescribed drug affects the individual. But from personal experience, once the apparent side effects reside, the next challenge is gaining confidence in yourself, your decisions, and your ability to preform task. Be patient with your self. Remember this: You will get better. And you will be able to preform as you did before. Just keep in mind that half of the challenge is getting back up again however cliche.

I have been on and off Prednisone for the last 8 years and I am still in my 20's. I suffer from severe asthma that just can't seem to be controlled even when taking the best medications possible. Well the best medications by doctors standards. Unfortunately I can have flare ups every month or every other month. If I am really good I can go two to three months without an attack or flare up. They can last a few days or a few weeks, it all just depends on the severity of the attack or inflammation and the course of actions the doctors and I choose to treat it. Which they always choose to do breathing treatments and a shot of steroids and then will give me and prescription of Prednisone that is usually 80-60mg for 3 days and I taper down to 5mg over a 10 day period.

I just saw the Pulmonologist who heard a light wheeze in my upper lung after I just came off a seven day taper of Prednisone, So she wanted to put me on 10 mg of Prednisone for three weeks until she saw me for a follow up. It drives me insane. I hate, hate, hate!!!! this stuff. But without it I start to close up and can't breathe and have no other options and trust me I have been to many physicians. I get the weight gain even if I don't eat. It makes you feel like you are endlessly hungry like you just can't get full not matter how much you do eat. The swollen round moon face that takes forever to get it's shape back. My hands start to peel on long tapers of it. My face breaks out and this is coming from a person who has never had a problem with acne. I have had all my upper teeth on the left side extracted even though I take care of my teeth.

It puts me in this mood where I don't want to be around anyone because I am so irritable that I don't want to risk acting out in a rude manner just because I am on this medicine. I have also experienced insomnia on it also even a few days after.

Now I know this medication has terrible side effects and if I had a choice I would not take it. I makes me miserable and my health ironically suffers from it. I fully understand that there are plenty of people who have the option to choose other forms of medications to use I would weigh pros and cons before taking prednisone. For the people like me who have to take prednisone. We can only hope they find some kind of alternative to this drug.

For the asthmatics who take this, I have been trying to limit dairy and meats from my diet and did get tested for everything to make sure I wasn't allergic to anything. Trying to make yourself healthy and as stress free as possible is the only thing I can come up with to try and stay off prednisone that much longer. Also my dentist said they have seen a lot more cases where the teeth are decaying from medication like this. Their recommendation to try to prolong and or prevent more extractions besides the normal hygiene care, is to make sure to take an extra calcium vitamin with your multi-vitamin and they say those medication can make your mouth very dry which increases a person's risk of gingivitis, tooth decay, and mouth infections, like thrush. So try and drink water or suck on sugar free candy or even using a room vaporizer to add moisture to the bedroom air.

Most of your friends, your family, they don't understand how you feel, or how painful this whole process is. That goes for short term and long term use. Being able to express how I feel and reading about other people who have experienced the same symptoms as me. I hope some of this helps a little bit. My thoughts and prayers go out to everyone on here.

I have been on 10mg Prednisone for 4 months for Polymialga Runatica and it helped immediately, but now I feel like I am 7 months pregnant with an alien child. My whole mid-section is huge and expends if I eat the smallest amount and it's hard to the touch. Other than that I have no pain and can walk and do things. However this large massive mid-section is hurting my breathing and makes me look awful (and I am a slim person). I can't get to see my Doc until 1/8 but I was wondering if anyone else has experienced this on Pred?
Happy New Year to you all, at least I hope it's Happy!

I am 30 and have had repeated on and off doses of prednisone. My pulmunologist? and my immunologist are extremely understanding about the fact I hate this medicine. Unfortunately it has saved my life numerous times due to my lungs and stupid immune system. So they try to do either quick doses or as low as possible.

My mom and I joke that when I'm on it and you see my cheeks are purple stay out of the way. They tend to get like that and then I get angry. Which I'm usually even tempered. It makes my heart race and I have heart issues too so they watch my heart and I get the sweats and chills. I get the insomnia which I am typing this after having received a high iv dose this morning I feel so sleepy but I'm restless.

I guess what I am saying is this medication is harsh and nasty but sometimes necessary. When needing this long term or even if once or twice a year get a dr you feel you can trust and if you have questions ask them, and if you are still nervous you can call and ask your pharmacist they are great assets to you.

I have moderate to severe asthma, and have been prescribed short tapering bursts my entire life. While I was in college dealing with an acute asthma attack and on prednisone, I became suicidally depressed. It happened again the following year (same reason for prescribing it).

I can take it if the burst is 10mg/day or less, tapers down, and no more than 7 days. The injected form does not seem to have the same side effects. As long as I follow these guidelines the most I have to deal with is a controllable melancholy. Unfortunately, I have other allergies and prednisone is often the only treatment for an acute episode of asthma.

I had been given prednisone because I am allergic to I.V.P. Dye used to give C.T. SCAN. The amount was 20 mg. every 6 hours. After 3 doses my blood sugars were 450 my blood pressure 194 over 84.. could not get sugar levels to go down even with fast acting insulin.

Any one else have this problem? I also have a very red face. irregular heartbeat. They have re-scheduled the scan but I am afraid to take this med. again.

As a Registered Nurse, I have noticed that short term prednisone side effects tend to hit females harder than males. I have taken short term doses of prednisone for hives, allergic contact dermatitis, muscle sprains and acute sinutsitis--about one time every year or two for about a decade. Other than some extra hunger and a little irritability, I have tolerated it well. Countless thousands of patients across the spectrum suffering from COPD to post-transplant patients count on and take steroids daily in order to live. Others take it short term with only minimal side effects.

What I have observed is that the smallest dose necessary should be taken. Patients do not have to be prescribed the standard "dose packs". The healthcare practitioner can prescribe a much lower, tapered dosing that can be filled by the Pharmacist. Ask your provider if a smaller dose regimen can be taken. For instance, if the doctor wants to prescribe a ten day dose pack of 5 mg. Ask if a lower, customized dose regimen of 2 or 3 mg. may work. Your doctor should be open to this.

Prednisone has been a god send for me.... I started having severe allergic reactions to almost everything I've eaten the last few weeks and lost 16 pounds from not being able to eat. Since being put on prednisone I have been able to return almost back to normal with eating and only experience the euphoria side effect with some minor aggression. please know what you are about to take before going on such a drug but in my case it's been the best decision until I go see a specialist

Hi everyone I'm 46yrs old now and I was diagnosed with MS ib 1999 my neurologist would put me on a high dose when I had an episode about once a year it was 200mg for three days then reduce by 5mg until I was down to 0. Then it was changed to Solumedrol which was a three day IV.

The stuff was nuts I would eat everything in sight and was wide open cleaning stuff my wife hid the vacuum cleaner from me because I would be using it at night. My boat and motorcycle was spotless but now I have trouble with painful joints knees, hand, fingers and shoulders. I wonder if all of the steroids caused some of these issues now

I have been prescribed Prednisone 20mg 3 tablets for 3 days and then 2 tablets for 3 days and Azithromycin 250mg 2 tablets 1 day and 1 tablet 5 days by ER as they found I have bronchitis and wheezing. Could not sleep on those days. But after they did pulmonary test they have prescribed me again prednisone 20mg 1 tablet daily for 7 days. Also they have put me on Symbicort inhaler 2 puffs every 12 hours for 2 weeks. Has anyone had this?

I had sharp pains radiating from my left ear, like I had an icepick shoved in my ear, every few minutes, it would make me jump or cringe every time it happened. Went to the Dr and he gave me ammoxicillin. 4 days later the sharp pains were gone but now had pressure in my eye and left sinus. Went back to the Dr. and they said I needed a shot of steroids and to give me a stronger antibiotic, Levofloxacin AND Prednisone 20 mg. for 5 days.

After the visit I started experiencing needle like pain on my forehead, eyebrow and hair on my left side. I took the prednisone yesterday and I cannot tell you how much pain I am in. If feels like my hair is made of needles, when I touch my forehead, it causes sharp needle like pain.

I have not slept well and yes, I did get jittery, but am sitting here now this morning deciding NOT to take the prednisone. Whoever said to way the pro's and con's were right. I have never felt pain, this bad, in my life. Give me my sinus infection any day, I am going out of my mind with this pain. Hopefully the shot and only one pill will not cause too severe of a withdraw. Glad I found this site.

I took Liprinosil about a month ago for ten days for HBP and stopped it because of ringing in my left ear. My ENT prescribed prednisone for 6 days for me for the ringing. I decided not to take it for fear it may make the ringing worse. Good choice? Suggestions?

I used to have tinnitus. I no longer do, although I cannot tell you why. It could be the magnesium and B vitamins I take or the occasional black strap molasses, which I take for the minerals in it. People write into earthclinic.com that apple cider vinegar with water and honey can help. Some say that anemia will cause ear ringing. As for HBP, I cannot recommend my ResPerate unit enough. Google it. The website has a lot of suggestions for controlling BP that do not involve drugs. I am off my Diovan and will never take it again.

Hi all. Found this forum tonight & am grateful as I was absolutely desperate. Again. I acknowledge that pred etc can save lives but its come at a terrible cost for me. I have anti phospholipid syndrome with Itp & was prescribed 50mg pred. I quickly became manic & would be awake & cleaning for 72 hours at a time & was drinking a bottle of cinzano a night & I normally never drink.

Had no effect. Drinking & cleaning with a dazzling zest for life. The trouble started when I reduced from 10mg to 5mg. I reacted like a heroin addict going cold turkey. Chills, nausea, intense body pain. Dr said to increase dose again & if I felt better it would indicate pred withdrawal. That was several months ago. I'm still on 5mg splitting the dose between am & pm. As soon as I try to reduce by even half a mg I begin having insidious suicidal thoughts. I have lost the ability to manage stress & have sworn at & abused my husband & 16 yo son.

I've become someone else. Things were a bit better in early December & I had stabilised but I began rituximab/mabthera infusions for the itp at end of Dec. This involves a 100mg shot of cortisol immediately prior to each infusion & its taken me weeks to realise that its messing with the pred effects. Now I find myself in s whole world of sh*t again. I'm either abusive & raging or remorseful & depressed. I apologise but my words seem empty.

I'm stunned that so few of my drs know anything about this whole withdrawal nightmare. Some of the people here have written amazing things & I'll return to read them when I lose the plot again. Btw I've been off work since July, put on 20kg, have moonface & camel hump. I sweat like a pig & have no appetite. I'm researching everything I can but sometimes I'm too mental to care. To all of you who are suffering much love & empathy. Thanks for what you've written. It's saved me tonight. Take care xxx

Prednisone helped me. It perhaps even saved my life.

In 1977 I was 10 years old and diagnosed with an autoimmune disease called polymyositis. I got so weak that I couldn't get up off the floor without help, and I couldn't even hit the bottom of a basketball net with a ball when standing under the goal. I was very weak. In addition to physical therapy, the main treatment was 6 months on prednisone. I recall that I gained weight and didn't grow in height during this time. When I stopped taking the medication, I grew 3-4 inches and soon lost all the weight. I don't think I've had any problems since then from having taken prednisone. And the disease went into permanent remission. I returned to playing basketball and it was as if the disease had never happened. I'm now 45.

I will add that from my mid-20's on I have had periods of mild to moderate depression...and after reading the above comments, wonder if this is a result of having taken prednisone. I doubt it.

Also, when I was younger I would get terrible rashes from poison ivy. The treatment was always prednisone, which got rid of the rash and also gave me incredible energy! I didn't need to sleep as much while on the medication and remember feeling that I was getting a lot done (because I was more energetic.) Last summer my mother took prednisone for poison ivy and she and a friend ended up painting an 8-room, 2-story old farm house. It's big! She's 65. Go mom!

I have been sick so I went to the Dr. and they prescribed Ciprofloxacin and they put me on 10mg Prednisone but 8 a day! with no decline in dose I decided to go down myself and not just stop them at once. Now I am sore to the touch! Everything on my body hurts even top of my head. I have been very moody and ill. I'm usually a very happy and cheerful person.. Are these side effects from this med? and How long will this last? I have been off meds for 2 days now

I have been on 20 mg of prednisone for a month and it is a love hate relationship. I was prescribed prednisone for chronic ulcerative stomatitis. I lived in severe pain for four years due to chronic canker sores on my gums, tongue and the inner cheek area. My mouth is completely clear I can talk and eat its great. I also have a lot more energy and my skin is very clear all over. However some negative side effects I am experiencing is insomnia, muscle cramping in arms and legs, heartburn, aggression. I think our next step is to lower the dose and see how low we can get and still stay clear of the canker sores.

I was diagnosed with Thyroid eye disease back in July put on Prednisone for 3 weeks 60mg, down to 20, after the last tablet was taken had an immediate reaction, of the problem .. referred to a well known Eye doctor here in Tampa who said I was weaned off too soon so he started all over again, put me back on Pred. again high dose, weaning down till December !!!..... I experienced all of the symptoms I have just read about, Anxiety, Insomnia, at times manic, huge weight gain, (and I am normally a thin person) Moon face, etc etc.

However I doubted the diagnosis, & went to see an Endocrinologist, she did blood work, & said my eye prob. NOT due to Thyroid!!! Advised me to go to U.S.F Eye Institute... That was last month (Dec) ... was still on the Pred, 5 mg.. after reducing to 2& 1/2 the eye prob flared up... The 2 doc's @ the Hos. said the diagnosis is Scleritis. I have been off of Pred now since Dec 19th, ( my moon face has gone, but still 20lbs over my normal weight) & now on steroid eye drops, & "Flubiprofen", weaning down from 3 a day, now 1... but I am having the same beginnings of the flareup again, Doctors said I need to see a Rheumotologist they feel there is an underlying condition causing this... they say, the next kind of treatment would be injections in the eye with steroids, failing that Methotrexate.... I feel pretty negative right now about the whole thing... & since coming off the Pred, I have had Swollen feet, my GP has put me on a diuretic & potassium as of yesterday.... what I am wondering are all these side effects due to coming off the Pred ?? If so how long does it take for the side effects to be out of my system...

I never want to take this drug again, it has been a night mare, of the worst kind !!

I wish all of you good peep's well & keep thinking positive, I always say "This too shall pass " I hope so.

Went to see my primary care doctor in December; had a lingering cough since mid November, couldn't shake it. He prescribed Nasonex but didn't help.

Went back in Jan and was prescribed Prednisone 12 day pack starting with 60mg a day then 40 then 20.... On day 9 I felt like I was getting a stomach flu, sweating, dizziness, weak, stomach pain, Heartburn and my face broke out. Stopped the Prednisone. Went back to Doc and sent me to see dermatologist.

Made appointment to see Gastro Dr. because I wasn't getting the Flu but the stomach was killing me. I suffer from GERD but it's been under control for years Nexium 40mg. Endoscopy shows stomach very irritated, worse than its ever been. Nobody wants to say that the Prednisone caused this. Don't take this stuff if you have GERD!

PEOPLE'S PHARMACY RESPONSE: Stomach/intestinal irritation, even ulcers, are a side effect of prednisone.

I think you and any other Lupus sufferer would notice a dramatic improvement if you 100% cut out ALL WHEAT, RYE (gluten) from your diet.

I'm just recommending this as I've seen it with my own eyes.

I am a 48 yr old female that at the age of 28 went to the doctor for a cold and received a prescription for prednisone starting at. 90 mg then winding down. This went on for two years, then I woke up one night to hearing my bones breaking in my hip., then on to waking up paralyzed. One yr. after all this insane pain and several hospitalization my Dr took another MRI and was told Ike that I needed emergency surgery and that until they got in their I may need to have to have my right leg amputated up to my thigh because they thought they seen what looked like tumors. How flipping scary.

Well come to find out what they thought were tumors ended up being large holes (bone farces) in my leg so then I had to have both hips replaced and I just completed my 3 hip revision last aug 28. They have a name that comes with. This it is called Avasculer Necrosis Disease which also I am now being treated for glaucoma. Prednisone caused all of this and I will still need a lot more surgeries in my future. I firmly believe that Prednisone is the DEVIL. I wish you all the best from the bottom of my heart.

This drug has saved my life and greatly reduced my hospital admissions. I have to admit I respond very well to pred (we call it my super man drugs cos after 2 days I feel amazing). I usually have 3-7 short courses a year (5-10 days max although I always request the 5 day course)I already take seritide 250 2x a day (sometimes 3) montelucast, hydroxizine, spiriva and lots of ventolin via spacer so when I get sick, a cold, random allergic reaction etc this is the only option I have (although the dr is considering a low dose of erythromycin to be added in.

It's not all bad on pred.. I admit I eat loads of protein but then often before I am so sick and unable to breath that I actually loose weight so I only gain a few pounds. I get very thirsty but then all my meds have that effect and I need to pee all the time but Ventolin to has that effect and if I need the pred then I need the ventolin. I always carry pred in my hand bag encase I need to use my epi pen (part of my emergency plan). My Dr and I have an agreement a short but heavy dose does the trick which limits the side effects to the days I am already off with whatever has caused the need for the pred.

My father on the other hand took pred for 2 years for sarcoidocis (spelling?) it took him a while to feel normal after he said it felt like having a strange flu or mild malaria. Every person is different but I have to say this drug saved my life on more than one occasion.

I have been prescribed Prednisolone 75mg a day for two weeks because of problems with my vision. I have now been taking this at this dose for 8 days and if I'm honest, I feel better than I have in a long time. The only negative side effects I've had so far are insomnia (terrible when you have to get up for work). I wake up at 2.15am every night and I'm awake until around 5.00am. Last night was the exception, I simply didn't get back to sleep! The other negative is that my vision is now more blurred than it was before.

Physically however, I feel great. No pain for the first time in 2.5 months and much better mental health. I feel "normal", like I imagine people are supposed to feel. No high, just generally happy with life. I've only been taking this for 8 days though. My eye doctor said I could just stop after two weeks but all the information I've gained so far says not to. I'll discuss this with him at my next appointment in 7 days time. For those of you who are suffering, I'm so sorry because whilst I was so afraid to go on this drug, I really have had a positive experience with it so far.

I was prescribed Nasacort for a sinus infection in August. 8 squirts a day as per my allergist - which by the way, is more than the recommended max dose. When I stopped them in September, I fell into major steroid withdrawal. I went back up to 4 squirts and over the last 4 months have slowly gotten off of them. Not one second of it has been painless - I've had nearly every symptom of withdrawal imaginable - nausea, diarrhea, stopped period, muscle and joint pains, dizziness, low blood pressure, insomnia, heart racing, fever, blurry vision, painful skin rash, inability to deal with even low stress, and (worst of all) massive panic attacks and anxiety which I had to start treating with Ativan just to exist. I have not been able to care for my kids because I've been bed ridden with symptoms.

What I will say is this - I was on a dose that is comparable to those taking prednisone. An endocrinologist told me to just get off of my last low dose of it. I am almost 4 weeks off and the anxiety is getting much better. Each day, I am experiencing a different symptom. Today I have the muscle and joint pain with skin rash. I figure that I will go through the rotation of all of the symptoms until my body finds its way finally back to normal. I have met friends who have gone through a similar experience and it is usually the case that the first 30 days following your last dose of steroid will be the worst, but things will slowly get better from there. I would say that is what I am experiencing.

Beware of all steroids! I would have dealt with stuffed sinuses any day over giving up the last 5 months of my life to this junk!

Thank you for your post. I am wondering how you are as I've had a similar experience in that I seem to be currently severely allergic to all food. Allergist has me on an "elemental" liquid diet (yuck). About to start 7 day Prednisone burst. Wondering if you were able to go back to eating once you stopped pred.? ever figure out what happened? thanks for any insight.

Thank you for sharing your experience. I am having the same issues. My teeth are dying from the inside and breaking above the gumline. They are crumbling like chalk from the inside. How long did it take you to get your teeth replaced and were u hospitalized while it was being done? who did it a dentist or an oral surgeon? Please help I am too young to feel like this.

I was diagnosed with RA in 1988 when I was 26 and was prescribed methotrexate and prednisone off and on for over 12 years. In 2000 I said "NO MORE!" and gradually weaned off both meds. The day to day side effects had become intolerable but at the time I had no idea how much permanent damage had been done to my bones and teeth.

By 2005 I had spent almost $25,000 on root canals, crowns, and extractions in an attempt to save some of my teeth. The dentist was the first health professional to tell me about all the damage these drugs, especially prednisone, do to teeth and bones. I was really angry that no doctor or pharmacist ever told me about the long term effects. Now I have osteoporosis, am on thyroid replacement for life, am in constant pain, and have eye problems in addition to ongoing dental issues.

In 2010 my RA flared terribly and I developed psoriasis on my ankles and lower legs. I refused oral prednisone and steroid joint injections but did use a steroid cream to help heal the psoriasis. I have used it off and on since 2010.

In August 2012, I again had a severe RA flare and the psoriasis returned with a vengeance. I started to use the steroid cream over a much larger area of my body. In Nov 2012, I had routine blood tests to check my thyroid, blood chemistry, etc. My liver enzymes were high which upset me because I never drink and I thought, "oh no, now what?" A few days later, I realized my liver enzymes were probably high because of absorbing steroids through my skin by using the cream for psoriasis.
Now my teeth and gums are causing problems again and I am positive the use of steroid cream has contributed to this. I am just so angry and upset but, y'know, it's my fault for dropping my guard.

I'm so frustrated after so many years of battling my own body. I've always tried to keep a smile on my face and focus on the positives in my life but I am beyond exhausted. I'm not sleeping, have no appetite, and have been in tears for days which is very unlike me. I feel so betrayed by the entire medical community. If only one person had stepped up in 1988 to tell me about the long term effects of steroids, I might have been able to avoid at least some of the problems I am experiencing now. But no one said a word at any time during the 12+ years I took these drugs. Instead they kept telling me to make sure I took all the meds, not to miss a dose, etc.
All apologies for such a long rant. I hope someone will read this and will be able to avoid all the problems I am battling now because of these drugs.
Thank you for allowing me to post.
S-.

I was prescribed 75mg of Prednisolone for 3 weeks, then 50mg for 3 weeks, then had to cut back quickly to 25mg for 2 days then 12mg for 2 days so I was off it before Orbital Decompression Surgery due to Graves Disease (Thyroid condition effecting the eyes). It is 5 days short of 4 weeks since I had surgery and I feel awful.....very very tired, no motivation, overwhelmed at the thought of doing daily stuff, sinus pain, irritable and unable to complete daily chores. Also fat face, tight around swollen areas in neck and legs, and swelling near collar bone. The pred didn't do anything positive for my eye as I still had to have surgery but I am worried that I may have done permanent damage to my body by taking it at such a high dose and also by not really weaning off the drug slowly.

As I had spinal fusion just a year ago, the last things I need is for problems with my bone density as my bones need to stay healthy, even though I am 58. I am still on Neo-Mercazole for my over-active Thyroid and was already taking Zoloft for Depression, which has been increased to 150mg daily to combat the mood effects of the Thyroid medication.

1. Does anyone know if 6 weeks of 75 - 50mg of Pred will effect my bones?
2. Does anyone know if there is anything I can add to my diet to gain some energy without effecting my endocrine system and thyroid levels? thanks.

I've been on prednisone twice, once for mononucleosis and once for wisdom teeth removal.

I have a less-than-average-tolerable case of misophonia; this made it completely intolerable. The first day while on prednisone there is no effect. But towards the end of the second day at the slightest sound of someone speaking an intense pain and rage surged through my head. Both times I ended up screaming and throwing things until I finally got tired and curled up fetal position while crying in a corner...
The second time it happened the doctor said I could take just 1/2 dose the next day then get off of it, as opposed to taking it the rest of the week. No problems after that, I didn't even have issues with swelling which was why I was taking it.

This happened to me too :( And I'm in between mh providers at the moment. 5 days at 30mg then 2 days tapered, for a virus that made me short of breath. The inhaler they gave me helped fine. I don't know why an ER Dr at a world- class teaching hospital would prescribe this to someone who disclosed to at least 2 nurses and one doctor that night that I have bipolar disorder. Not even a warning. Nothing about mania or ANY psych side effects on the PI sheet either. It's been weeks and I'm still trying to get stable. Do I have any recourse? Most Dr's keep saying, Oh it can do that to people who aren't bipolar at all. Well, I really don't care - I want my life back!

I have MS and in Jan 2013 I was prescribed a high dose of oral Prednisone to bring me out of a major relapse. Most of the information I could find about Prednisone was for long term use or otherwise wasn't specific for the extremely high dose I was given. I was prescribed 1000mg of Prednisone per day. This is not a typo. This is the currently accepted dosage to treat MS relapses.

I had to take 10 x 50mg pills with breakfast and another 10 at dinner time. The hardest information for me to find was how long the side effects would last after finishing the course. So, now that I know, I want to post the answer here in hopes of helping anyone else in a similar situation.

I started the Prednisone in the evening of Jan 14th, 2013. My relapse had been progressing noticeably on a daily basis at this point. After that first course of 10 pills my MS symptoms had plateau'd by the next morning. My last dose of Prednisone was taken on Jan 17th (3 days, 20 pills/day). My MS plateaus usually last for weeks before the symptoms gradually fade away, but by Jan 18th I was back to walking, vision had fully returned, and lingering skin sensitivity was fading.

My Prednisone side effects during the 3 day course consisted of: severe stomach upset, severe insomnia, occasional head ache, bowel issues, mild feminine issues, and random spots of stinging on skin (ankles, knees, arms).

My Prednisone side effects after completion of the medication: random hives (large hot and red itchy patches), distraction, mild back pain/stiffness, jittery/shaky, high energy, anxiety, strange acne, floating sensation, slight bleeding of the gums, hunger and sugar cravings, occasional swelling of feet, legs or ankles, forgetfulness and mild confusion.

Here's the timeline of how the side effects left:
Day 1 - (first day of no new Prednisone) MS symptoms decrease so much that I felt I could return to work. Stomach mildly upset in the morning but felt fine by evening with no recurrence later. Feminine and bowel issues end by evening. Joints mildly sore, took Glucosamine.

Day 2 - slept through the night between Day 1 and 2, but insomnia returned next night. Jitteriness, anxiety, and hives began on Day 2.

Day 3 - Sleep back to normal.

Day 6 - No longer feeling jittery. Hives and swelling still occurring. Occasional migraine. MS symptoms still fading. Joints and back no longer sore, except right knee (MS related not Prednisone).

Day 18 - Still getting weird acne, hives, cravings for candy. Relapse symptoms gone, except for lingering right knee stiffness which is much milder than before, but never fully resolves.

Day 20 - Back to normal. Side effects gone, MS relapse gone (excluding right knee)
1 Month - shoveling snow, driving, socializing, life is good

I am one of those who love/hate Prednisone, but could not function without it. 29 years ago I was diagnosed with Meniere's disease, over the years lost most of hearing in left ear. Short course with tapering of Prednisone was able to somewhat stabilize the attacks. About 6 years ago, awoke one morning to total hearing loss in both ears. Was seen immediately by my long-term ENT. Diagnosed with "Autoimmune Inner Ear Disease".

This has more recently become scientifically associated with previous Meniere's Disease diagnosis. If this is treated very quickly (within 1-3 weeks) very good chance of remission. I have had recurrences approx. 6-7 times since. My total life saver has been with Prednisone. Although I also get many severe reactions from the medication, including the last time a severe psychotic reaction (again swearing to never take it again), once again I am grateful for Prednisone for treating a new attack.

Usually I am able to gain most of my hearing in my "good - right" ear. I will never again be able to hear from my left (Meniere's ear). If I didn't have Prednisone I would most likely lose total hearing in my right ear, resulting in total, permanent hearing loss - Deafness!! Please be very careful when you say "Never Again" or to put "Allergic" on your medial charts. You never know when you may truly need this medication.

I too had retina reattachment and was put on the prednisolone eye drops for 6 months. I finally had to say something to the dr about wanting to stop as I no longer saw any advantage for it. I had several side effects such as pain, on the verge of migraines, swollen face, dilated eye, sleeplessness. Everything went away but the swollen side of the face which is now a swollen jowl. It has been 8 months and I sure hope it will go away!!

Man, I'm way too familiar to this for it to be healthy.

I've been on prednisone since July 3rd 2012 for chronic pericartidis, a complication from open heart surgery to correct a right coronary artery anomaly I discovered after having a heart attack in PE. LOL. I laugh at this cause it's just so crazy at how much the body can go through and endure. I'm 16 and I've been taking about 60mg everyday and tapering every third day by 5mg. Whenever my dose gets down to 5mg though, I start getting severe pain and pain to the point where I can't walk or talk. Not because of the side effects but because that's what pericarditis does.

I've tried to manage without prednisone but the pain gets too extreme that I give in to it. I've fainted in class from my pericartidis, it really is so painful and weakens your whole body.

But the side effects, smh. I've gained 50lbs so far, and my hair grows crazily fast, my face is always flushed red, I'm sweating a lot, I'm hot, I'm pissed, I'm angry, and a general feeling of icky ness. Horrible medicine, but I need to take it to survive :/
Sometimes it doesn't seem worth it.

I am going through the same feelings. How long until you felt some kind of relief from these symptoms?

My last entry was Jan.19th this year .. I had been off Pred for approx 1 month ... ... I had been on Pred for 6mths ... gained 20 odd Lbs .. had terrible side affects like you all ... but I am feeling so much NOW like my old self... not manic any more ( and I was told how erratic I was behaving etc !!) my moon face is gone .. yeaaa.. I have lost 10lbs & working on the other 12 .. with the Mediterranean diet .. I am SLEEPING again ..... I am again UPBEAT.

Ok my eye prob. without steroids has been OK I am now weaning down on steroid eye drop's 1 a day next week I eye drop every other day & Florubiprofen , 1/2 every other day, but I tell u after reading all the letters .. I will NOT go on Prednisone .... unless its life or death

Also a lot of doctor's are NOT WARNING / telling / Patients / They need to wean down VERY SLOWLY ... & sometimes .. for some things .. find something else to take ..NOT PREDNISONE .... every one needs to spread the word about the warnings @ Dangers / side effects ...

Good luck to all who are suffering, find another Doctor who is "clued up " MANY ARE NOT ... if you need help .. a good endocrinologist should be able to help .. & last of all do not doubt your self EVER .. be pro active in your health care. Love & Blessings to all of you who are suffering.. have FAITH .. THIS TOO SHALL PASS :-)

Well I'm glad I read all your comments because I thought I was unable to stand it another second. I took prednisone twice in my 32 years. The first time I quit taking it after day 6 not knowing that was bad. I became a manic depressive in a split second I had never had depression before so I freaked. I drove my family crazy with my craziness. It took two weeks for me to recuperate and I had to leave my old apartment because just being there made me remember my horrible experience. I took prednisone again a week ago. I have been a mess of bloated fat face and stomach. I still can't breath from asthma. I go into manic spats of crying and I can't get the anxiety under control. I wake up with my heart racing. I feel like I'm having an attack of the central nervous system. I went to the er and the Dr Said there's nothing you can do. They gave me more after they made me crazy with the drugs in the first place.

I was given buspar which is like Prozac and told to down some benadryl. I am not normally ever depressed or have anxiety that was this bad. Drs give you a script and they don't warn u I feel like a raving lunatic. I can't do anything without overreacting or crying. I am insane. I thought of admitting myself into a psych ward but I turn to prayer. It has helped me to not lose it completely. I surround myself with family and friends who I am absolutely driving crazy too. But I have faith in the lord and I will get through this madness. I will pray for all of u out there just know you're not alone. HAVE FAITH AND GOD BLESS

Latoya, I just read your description of your symptoms and it reminded me of Reader's Digest article I read in the last 30 days about a woman with symptoms similar to yours, especially the acute hearing. She finally found a doctor that recognized her symptoms and was able to treat her for some rare condition. Unfortunately I don't have the magazine any longer, and I can't remember the nature of her condition, but I suggest you could search the last 2-3 editions of Readers Digest to see if you can find her story. Good luck!

My father was admitted to the emergency room for an attack of emphysema. He was later admitted for a total of 5 days. After 2 days of being on IV predisone, he developed confusion and he imagined bizarre things happening. He kept looking for people and he thought he was at home. It was so bad, the hospital staff had someone stay with him a night so that he would walk off or go to another room.

Once he was discharged from the hospital, his mind seems to have returned. However, he is finding it difficult to determine what was real and what wasn't. He is 82 years old but NEVER showed any signs of dementia prior to the hospital stay. We are hoping it will never happen again. Has anyone ever heard of this problem/situation while taking predisone?

When my father had heart bypass surgery in 1989 he developed personality changes while in the hospital. My parents lived in another state and my mother related his confusion and paranoia to me. I happened to mention it to a neighbor who was an OB-GYN. He said that people in intensive care units often experience confusion and exhibit personality changes because, he thought, they were living in artificial light and had no way of telling night from day.

He predicted that my Dad would do MUCH better once he got home, and to be sure that Dad sat near a window every day. So although some of the effect may have been from Prednisone, I wonder if your father's experience doesn't bear this idea out.

Thanks so much for your reply. He is doing much better mentally. We still believe it is medically caused. However we will never know.

I am searching for information regarding being given mega doses of Prednisone in a hospital and not being consulted or informed. By mega doses I mean 600 mg one day, 580 mg next day, 490 mg next two days. An endocrinologist and a pharmacist viewed as likely fatal doses. Definitely cause steroid psychosis. I suspect they gave me these for an adverse event - this is denied by the hospital. I suffered excruciating pain throughout my body - ruptured shoulder cuff, crippled - still can't walk and had no crippling prior. Any feed back on such high doses? I had total insomnia, wasting, and a general feeling of being 100 years old.

I wish I had seen your comments before my husband was prescribed Prednisone for a breathing problem. Years ago he was diagnosed with bi-polar disorder, but did ok without medication for years (as long as we put up with his quirks and OCD he was ok.

As soon as the Prednisone tapered off, he began having really bad panic attacks, he would hyperventilate, shake, gasp for breath. he swelled up so badly in 2 weeks he looked pregnant and his legs were covered with whelps, swollen and began oozing fluid. He is now in the hospital CCU with the Drs thinking it is a allergic reaction. It was certainly worse than the breathing problem for which it was prescribed

Horrific stuff. Of course, the hospital denies everything. I know in my heart, the predisone caused my dad to have dementia symptoms. He was worse when it was given through his veins. (I never knew what his dose was.) When given an lower oral dose, he started to get back to normal. He was given this large dose due to a COPD attack. He was in the hospital for 5 days because of his mental state. Sounds like your symptoms were worse. Best wishes to you.

I was prescribed prednisone 20mg 2 tablets, I took one thursday the other one on friday for some hives rash skin, however, on Sunday morning I woke up loopy, vomiting, headache, and weak. Can anybody tell me if I'm suffering from side effects? I'm still in bed as per today, with same symptoms. I feel very awkward and bad.

Hi I was wondering if anyone can relate to my life.

My husband took predisone 100 mg for 6 months for some vision loss he experienced.
That was approximately 15 years ago. I feel like that was the last time I saw my very loving husband. Since the predisone I feel like it stole his awesome personality. He has had a complete personality change.

This has taken me many years of searching but I have come to the conclusion that the predisone may be the reason for his change. Can anyone relate to this? This is a change he can not see for some reason. It is like he does not have the ability to care anymore. Although this did seem to help his vision loss there are many days I wonder what he would be like without the predisone,

I'm on prednisolone which is the same steroid I have been given them for an IBD which has not been diagnosed I've been on them for 7 weeks so far and still have 3 months left at a reduced dose from 40mg I hate it because I can't sleep I have painful legs my eyes itch I keep feeling down and cry a lot I've even been taking things without paying for them and not realised until I get home .. I'm wondering about not knowing where I'm going or what I'm doing .. shaking all the time feeling sick and anxious like nearly everyone who has taken these drugs I was not warned at all about this and when I mentioned some of the side effects to a doctor in the hospital I just got an oh dear try get some rest !!!

I was given prednisone a week ago and I am still currently on it and I am only 14 years old It was prescribed to me because I broke out in hives and after a few weeks the doctors decided it was an auto immune disorder.

I have an appointment to go to a specialist but its not for another month and I have been getting light headed and I am worried about all of the side effects that everyone has posted. My physician never informed me of any of these side effects!

I have taken the Medrol Dosepak probably 4 times over the past few years for sinusitis or bronchitis. I have never had a bad reaction - on the contrary, it made me feel very good. I felt very energetic, awake, feeling like I could clean the whole house with energy to spare. Again, this is a six day graduated dose of corticosteroids, and I took the entire day's dose each morning with food (instead of the package directions since I was told by the Pharmacist that it could keep me awake). That worked very well for me and my sleep was not disrupted. I was surprised to read about the serious side effects. It has always helped me when I've had problems with sinus infections and I've always felt much better with the Medrol Dosapak. Maybe it gives me a mild "manic" reaction? All I can describe is that I feel very energetic in a good way.

Took my first of 7 20 mg tablets prednisone early last evening. It was prescribed on the off-chance that the severe coughing I've had for nearly 3 weeks, along with other pains, might reduce a hypothetical inflammatory process. (It certainly feels like it to me). I am severely fearful of medications.

After the prednisone took effect, I felt calmer. The sense of inflammation was greatly lessened. Coughing decreased. I slept very well, save for waking with mild pain in both feet, and some tingling, which may well be due to other factors. For me, it is worth the short-run - I think. And, I may have paradoxical reactions to the drug. More concerned about what has happened to my ability to breathe well; all worst-fears being quite possible, if not probable.

I appreciate reading other experiences, but do hope that useful effects are noted.

I've been on prednisone for about 6 years, varying dosages. I'm currently tapered down to 10mg/day. I was prescribed it for very severe eczema (severe enough to be hospitalized a few times, and at those times I got IV solumedrol).

Since then, my weight has more than doubled. (I have lost 35 pounds since I was at the highest, but I have a lot more work to do. Also, I used to be in very good health and very athletic, so it annoys me when doctors say "just eat right and exercise!" If it was that easy, I'd have done it already). This has caused bad stretch marks, thinning skin, sweating, hot flashes, also.

I also developed diabetes from pred and weight gain (I am 32, and I was thin before pred, no health issues besides the eczema). I also have high blood pressure, IBS, Cushing's syndrome, sometimes I get numbness in the extremities.

I have cataracts in both eyes and will probably need surgery (next appt is in 2 weeks, then I'll find out). I also developed massive dental problems, decay, cracking, sensitivity. I feel like having them all pulled and getting dentures is inevitable at this point, and they used to be healthy. I've sometimes grown hair on my face, and a few times I went 6 months without a menstrual period.

The psychological side effects are what scare me the most, I am tired, I can't concentrate, I have memory issues, panic attacks, depression, and it feels like a lack of willpower, I just don't care about anything, which impacts my jobs. I have trouble accomplishing much in a day, between the tiredness, confusion, and what feels kind of like ADD (undiagnosed though, I can't afford a psychiatrist when I'm seeing four other specialists). No one seems to believe me about the psych effects of the drug, even though many of them are mentioned on the side effects sheets you get with the prescription. I failed college classes and lost jobs from these things. The whole thing has been a nightmare, but I'm dependent on them now and it could take years to get off them.

I feel everyone's pain, unfortunately. I was prescribed 50 mg of prednisone for 5 days during a trip to the emergency room for an allergic reaction. After I was given the first dose before I was discharged, my skin turned mottled and I felt as if I were in a fog like state. Hours later I had to make another trip to the emergency room later that night as my hands and feet began to swell, my breathing became shallow and my heart wouldn't stop racing.

How I was able to remain on prednisone for the 5 day course and remain sane at work & home, I do not know. I would start each morning with a racing heart, a heavy chest, an odd heavy sensation in the back of my head accompanied by a headache, hot burning skin, blurry vision, swollen hands/face/feet, and a foggy/confused state of mind. These symptoms would last throughout the day and sometimes well into the evening.

After a doctor's checkup, my doctor prescribed 18 more pills of prednisone in order to ween myself off of the medication, and to help with my unknown allergic reaction in case I had another episode. After finding this website and tracing my symptoms back to prednisone, I threw the rest of 18 pills in the garbage.

I have not had another allergic reaction yet, but I will take my chances with benadryl and my epi pen if needed. I wouldn't wish this drug on my own worst enemy! The side effects were absolutely unbearable and worse than what I had originally made the visit to the hospital for!

I am on day 3 of 12 of a tapered regime of predisone for an extreme dermatitis flare up. I've been battling allergic contact dermatitis for years, have worked with a dermatologist to identify and eliminate chemical allergens (patch tested for over 200), but have also noticed I react to heat (exercise, outdoors), and am also currently trying a grain/gluten free diet to see if that helps. I have resisted pred to this point, but after waking up with my face completely swollen after an evening in outdoor heat, I knew I had to get some immediate help and agreed to this 12 day course.

Today was my first possible side effect - feeling a little spacey in the office, but that seems to have passed after eating some yogurt and an orange, so perhaps its my recent dietary changes, not the pred. No sleep trouble thus far and my skin looks completely clear, which is actually quite shocking to me visually after having had serious redness and inflammation for years. I am hoping that by keeping up the anti-inflammatory diet while I am on this course of meds, that this will all be a turning point. I am also working with an acupuncturist - trying to cover all my bases. If anyone has had a similar experience, I would love to hear your story.

OMG...I am a heart patient and just got off 14 days of predisone. Now I have cramps (Charlie horse) in my legs, arms, hands and across my chest. Never again will I take this drug for sinus infection. I will either suffer and live with it, or do natural remedy.

My NP (a co-worker) put me on 20 mg of predisone twice a day for 5 days last week. I have taken it in the past and it made me a little moody, and my thighs swelled up like tree trunks. I told her I never wanted it again. Well, last week she put me on it again for bronchitis and an ear infection "even though she knows I don't like it".

Four days into it, I could not stop crying. I cleaned my house from top to bottom, then decided to make pizza for dinner. NOT a good plan for someone who can't stretch a pizza crust under normal circumstances. I flew into a fit of rage, and having no control over my arm, stabbed the cooking sausage all over the (freshly scrubbed) kitchen and living room, then sobbed my eyes out wishing I could die as I cleaned up my giant mess.

I am not taking day #5, and hoping that my mood swings calm down today. On top of all that, my bronchitis is not at all better. The next time someone tries to prescribe me prednisone, I had better be unconscious and on the brink of death. NEVER AGAIN. I think I will actually put that into my living will.

I have severe asthma and have been on prednisone more times than I can count. It is in fact a "miracle drug". I had reactions like many of the others are speaking of but only the first time I was prescribed the medication. I have NO reaction at all anymore. This drug obviously has a different affect on everyone. I love you prednisone!

Is it possible that short term use of prednisone can cause shortness of breath and difficulty breathing? I am experiencing asthma type symptoms. I have been on the drug for 1-1/2 weeks now.

Does anyone else have a numb tongue or lips? I was going to ask something else, but I forgot what it was, so, yeah, I got that confusion/trouble concentrating thing going on, too.

I've been on this stuff for 6 days now to clear my severe reaction to poison oak, ivy, sumac, pick one. It's worked miracles with my reaction. However the increase in my heart rate is keeping me from heating and energizing me to exercise more. Sleeping at night is the only negative effect I'm having. I start reducing my dosage in the next 2 days and looking forward to a better nights sleep!

I think the important thing here is to go back to your Drs if you are worried I have taken preds for serious asthma and find they do keep me alive but I have all the side affects mentioned not every time and not always all at once but they do keep me alive. I feel they should only be taken for life threatening issues but I am not a medical expert and suggest you get more than one opinion because you would be surprised how many Drs vary with theirs Take Care TJ

I'm so sorry to hear all the horrible stories from everyone who have had side effects from taking prednisone. I am 37 years old and up until this point have been a very healthy person and have never had to take medication regularly.

In mid April I was diagnosed with an autoimmune disorder of the liver. I was put on prednisone 40mg for two weeks due to the fact that my liver levels were off the charts. I have to be monitored weekly with blood tests to ensure that the levels go down and stay down as I am allowed to take lower doses. I went from two weeks of 40mg to one week of 30mg and today was able to take 20mg for the next week, then down to 10mg for a week then 5mg until I am off totally. I will say I also have to take 100mg of Imuran a day to suppress my immune system so it will stop attacking my liver. The prednisone has helped lower my liver levels until the Imuran can build up enough in my body to keep things in order.

I was very hesitant of the medication because I have never been one to be dependent on it and had heard of some of the side effects of prednisone. In my case it was life or death. I was already in stage 2 of liver fibrosis due to the damage the inflammation in my liver was causing. My doctors have been so supportive and forth coming with the possible side effects.

I will say it has been a really tough transition!! I have had to deal with some of the side effects as well Moon Face so sad this has been so hard, acne which has been awful on my face, neck, and arms, not sleeping, gaining weight, red face, also feeling emotional or grumpy at times which I hate!! since I am a not that way on a normal bases, also the charlie horses in the middle of the night are awful. I am like everyone else praying that after I get off the prednisone that my body will adjust back to normal as far as the side effects go. I will say that my family has been so supportive and that leaning on and trusting God has been my lifeline. I will be praying for you all as you walk through these illnesses that God will grant you and your doctors wisdom, bring comfort to you, and for complete healing in your bodies. God has been so good to me put me in touch with great doctors and it has been quick and believe me I have had to go through a lot to get a diagnosis, lots and lots of tests, biopsy, etc. Also for my levels to go from almost 1000 to almost normal in a week is just a miracle as they had been rising every week prior.

With that said the side effects are very emotional to deal with a times and I am going to be so excited to get off this medication all together. For some of we just have to grin and bear it. I know for me personally God and my family and friends have made that possible. I will try to post again after I get to go off the prednisone to let anyone who has been asking how long it takes for the side effects to go away. I know everyone is different but hopefully it can bring hope to someone.

God Bless,
MT

Three years ago I was diagnosed with Hodgekins disease. Six cycles of chemotherapy included taking 100 mg of Prednisone seven days in a row with a two week break in between cycles. My legs/thighs turned to jelly. I never regained my strength. One year after achieving remission I relapsed and underwent a bone marrow transplant.

The chemotherapy prescribed included prednisone. It has been one year and four months since my BMT and I still have not gained any strength in my legs. Walking is a chore. Climbing steps is extremely difficult. My doctors say there is no correlation between my chemo and my muscle weakness. Info attained via the internet supports the correlation that prednisone has all to do with my loss of strength.

I'm interested in hearing from others who might share my experience with prednisone. Oh...
On the bright side..I'm alive!

I have avascular necrosis from steroid use for asthma. I have had both hips replaced and both shoulders. I was off them for two years and now after a bad attack, back on steroids. I have high blood sugar, my feet are numb, and my hair is beginning to break once again. Except for the hair that is growing on my face. I am swollen and depressed.

After forty years of taking steroids off an on, my body is destroyed, even my skin has broken down and I have stretch marks from the steroid use.

Dont use unless you are dying and even then think twice.....

my dr has put me on 7 day course of prednisone 25mg but has said I don't need to wean off it just stop after 7 days is this ok to do?

People's Pharmacy response: It is unorthodox. Usually the dose starts high and tapers down, but perhaps he feels that 25 mg is not a high enough dose to be tapered.

I went to the ENT for a refill on a nasal spray yesterday & not only did I leave with that, but I now have to use 2 & left with an antibiotic for 21 days & prednisone for 21 days due to my chronic sinus infection (did a CT scan). I am very nervous to start taking this as I feel it is a high dose for me. I start with 30mg for 7 days, 20mg for 7 days & then 10mg for 7 days. I have been googling the recommended dosages for chronic sinus infections & it's all different. If I need it, I need it, but the side effects scare me like crazy. Any suggestions? Should I cut it down? Thanks!!

Hello there all. I have been using prednisone on and off for about 4 years to treat outbreaks of Henoch-scholein purpura, a form of vasculitis. It affects the small blood vessels in my legs but recently has been found damaging my kidneys to the point where I only have about 27% function left in them. Scary stuff. There is definitely a "honeymoon" phase of the drug in the beginning where you do indeed feel like you are super human. For me, this typically only lasts a few days before the insomnia, rage, and uncontrollable eating sets in. Then the self loathing begins.

Normally, I am a very outgoing, fun-loving, optimistic person but there is something about this drug that tries to suppress all of that. Given my condition though, it seems as if fate has brought me and this terrible drug together, so I try and make the best of it. The weight gain, insomnia, and swelling aren't exactly a picnic but the mood swings are what is driving me insane. I like to joke about it-describing it as "hulking out" because that is how I feel, only I don't turn green and large but I do like to smash and throw things.

I have spent 4 years feeling like a monster when on this drug, but knowing that I'm not alone has been a comfort to me. Thank you all for sharing your experiences! It's tough when you feel like you're fighting a losing battle with your body but the optimist in me knows that attitude can change anything, if it's the right attitude.

I have been treated for rheumatoid arthritis [RA] for 26 years.

I have recently failed Humira and my Dr and I are trying to come to an agreement regarding which med will be used next. In the meantime I have been on prednisone 5mg in the am and 5mg in the pm (now tapering the am dose).

I am so depressed, suffer from insomnia, which I am sure increases the depression because I don't have the energy to do what I want to do. I also feel like my leg muscles are weak. I love to walk and right now I am lucky to get around the supermarket (hanging on to the cart no less).

I have been tapering off at 1mg per week starting with the morning dose. Has anyone heard of tapering off a twice a day dose this way? I can't wait to be totally off this drug.

I will NEVER take it again. I am tired of no sleep, crying, and feeling useless. I used to travel a lot and no longer have the energy or confidence to do so by myself. After reading some of the posts, I am hopeful that once this drug leaves my system I can get back to normal.

I would rather deal with the RA pain. Thank you for all the insightful posts and letting me vent. I am not lucky enough to be around anyone who understands this (the prednisone issue or the RA). I guesss if you don't have something it is hard to understand what others are suffering.

Hello - Am a 84 year old male, in reasonably good shape and was diagnosed with Giant Cell Arteritis 4 years ago. Started on 60 mg prednisone and over 6 months tapered to 5 mg.

Contrary to most of these users, am doing great with the pred except for sleep, a minor issue with me. Occasionally I will get a flare but is easily resolved by popping a 10 mg for a day or two.

My Rhumy explained to me in great detail what to expect, the sleep thing, bone loss, weight, etc.

One thing all posters have failed to talk about is DIET and EXERCISE !! very IMPORTANT!! a MUST!! Before starting, get a good, local, Rheumatologist, A Dietician and check out their credentials. -- Hope this helps you and good luck to all my fellow PredHeads.

I am a 72 yr old female I was also diagnosed a liver decease last September I feel very fortunate that it was caught in time and saved my life but now I am wondering if the mental problems eg anxiety panic attacks and severe depression will get better I don't expect to ever be the women I was and can except that but although I am doing well with the liver problem I go on much longer feeling this way mentally as I am not a very nice person to live with at the present time I am now on 3mg of prednisone and 25mg of azathioprine mg I have been told it takes a long time to get out of the system could someone let me know please.

I was diagnosed with acute bronchitis and put on prednisone 60 Mg a day. The first day I took that dose I thought I was losing my mind. I had insomnia that first night along with racing thoughts and depression. I called the doctor the next day and a nurse told me to only take 20 mg for the next four days and then stop altogether. For the remaining four days I had severe mood swings, increased appetite, extreme dizziness and disorientation. I did not feel like myself and really thought I was going crazy.

I took my last 20 mg pill two days ago. The day after my last pill my body was so sore it felt like I had been in a car accident. I gained at least 5 pounds in the five days i was on it and I am still having very bad dizzy spells with fatigue. My appetite is still out of control 2 days after my last dose and I still feel dizzy and not normal.

I never ever would have taken this drug if the doctor would have warned me of these horrible side effects. I would rather have developed bronchial pneumonia then deal with these horrible side effects. My heart goes out to anyone else dealing with these horrible physiological symptoms from this drug.

I was given 10mg. of prednisone to treat the inflammation caused by Rheumatoid Arthritis. A few days after taking Prednsione my feet, ankles and legs began to swell very badly. I was sent for CAT Scans, echocardiogram, and Venous Ultrasound to determine the cause of the increase of swelling in both my feet, ankles and legs. All the tests were negative.

I have been off the prednisone about 5 weeks and did discontinue it gradually. The swelling continues and no doctor can tell me what is causing the swelling. I am very frustrated because the swelling increased after taking the prednisone but no doctor has told me that it could be side effects from taking prednisone. Why not? I feel like I am being ignored now that the tests were negative but the problem still exists.

After reading some of these comments about Prednisone I realize that I am not alone in thinking these side effects could be caused by Prednisone.
If anyone could shed some light on why my feet, ankles and legs continue to swell I would appreciate some explanations.
Thank you

I just started this prednisone 20mg. but before I read the side affects. I told my wife that my back was hurting more than that I can stand. I got a bad back and the meds don't help my back at all. I have to double up my pain meds. to work the entire day. I hope that I don't have as much trouble as some of y'all do. my prayers go out to you all.

I have neck psoriatic arthritis, and no rheumatologist will take my ins. so my doctor put me on pred. it has helped so, so much, but now she is lowering the dosage because she is concerned for the long term effects. it's sad when you have to take this avenue. I would love to see the proper doctor for my condition. I hurt so at times,unable to even function, get up, lift a grocery bag. if anyone can help me let me know. deborah m.

I was prescribed to take 3 20mg tables for the next five days. Does that mean I will be taking 60mgs daily? I suffer with COPD, HIV, and hep C. Should I see my PCP prior to taking this? The blogs I have read scared the day lights out of me. I may have to wait for a few days to get an appointment and wonder should not take. I would appreciate any suggestions before following the emergency room doctors orders I received tonight August 15th 2013. Concerned patient!!!!

People's Pharmacy response: You will be taking 60 mg a day, but that may be what you need. Why not call your physician's office to get advice?

I feel for everyone who has had problems with Prednisone but we need to remember sometimes it is the only thing that can help some medical situations. Several years ago I was on a very high dosage, 60mg for about 5 days for welts. I don't mean little bumps, I mean huge boiling blister type things ALL over my body. I had terrible side effects to the prednisone, anger, insomnia, etc. These were however nothing compared to the welts. As bad as the itching was the psychological stress was the worst part. It is hard to say if the welts would have gone away if not for the prednisone.

I now have a respiratory condition known as Bronchiolitis obliterans with organizing pneumonia (BOOP). Prednisone is once again my friend. Am I having side effects, absolutely, but hopefully they will be short lived compared to the long term suffering I have been through with BOOP. I went from running 6 miles every few days on trails to not being able to walk up a flight of stairs without stopping and having to sit to catch my breath. I have had months of diagnosing to determine what might be going on and so have had a lot of time to try alternative and homeopathic remedies. Some abated the symptoms a little but nothing resolved the problem completely. If going on Prednisone will resolve this then that is what I am determined to do.

Every person should evaluate the side effects against the benefits. It disturbs me that Doctors pay so little time speaking with their patients about the side effects of "the devils candy". I am sure if they did and prepared people for what was to come and explained the necessity of using this drug there would at least be more tolerance of the side effects. I am also disturbed by what I see as the sometimes unneeded prescription of it, as a first and only course of action. For the BOOP it has been 4 month and only now am I starting Prednisone after attempting other treatments first.

Well I always come home and check the Internet after being prescribed anything that I don't know about by my doctor... And I am seriously glad I did this time. I've had terrible sinus pain for the last few days, and an awful cough, I've felt terrible. Doctor has prescribed me Prednisone 25mg. He has advised me to take 2xtablets for 3 days, 1.5 tablets 2x a day for the next 3 days, then 1 tablet for 3 days then half a tablet for 3 days.

I filled the prescription right after I saw him, but thought I'd check up about it before I took the first one when I got home. THANK YOU EVERYONE for sharing your horror stories!
Because of you all there is NO WAY ON THIS EARTH I AM TAKING THESE PILLS! I'm going to post this comment and immediately go throw the bottle of pills in the bin ( garbage collection is tomorrow).
I will put up with sore sinuses, and hope it clears up, if it doesn't I'll go back to the doctor and tell him that he better have something else to give me because there is NO WAY I'm putting that Prednisone poison in my body.

Peoples Pharmacy response: Please don't jump to conclusions. Although there certainly are times when prednisone is inappropriate and causes a lot of trouble, there are also times when he can be extremely helpful. Remember, the folks who post here are the ones with had problems. The ones who have gotten benefit don't have a good reason to post their experience.

When will this nightmare end? I am suffering from severe psychological effects from this medicine. I cut all pills 2 days ago but the lingering dizziness is killing me. I can't stop crying. I can't focus.

Thanks for the response People's Pharmacy :) But for a sinus infection, these side effects are WAY too much of a risk to take! If I had chronic illness and had tried everything else, sure I'd risk it to get better, but there are PLENTY of ways to treat a sinus infection that I can try first and do not have the potential side effects of suicidal thoughts, bones and teeth rotting away, and my skin hurting to touch!
The Prednisone went DIRECTLY IN THE BIN unopened and untouched, along with the repeat script. I've gone back and gotten a normal boring course of Amoxicillin, which is nice and safe lol. Doctor said it should do the same thing for sinusitis, but he doesn't like to prescribe antibiotics. I told him that unless its life threatening, don't prescribe me dangerous things again!

My sympathys for your problems.
I have just discovered that the 20 Mg predisone tablets prescribed for my olecranon bursitis has cleared up the problem of my feet suddenly going to sleep when standing due to spinal compression at the L4-5 junction. I am delighted to find this as I have been suffering from this problem for several years. It is clear that even though I have spodilolesthesis, the problem can be aleviated by simply reducing the inflammation with prednisone. It took about eight days for the effect show up.
Incidentally, the olecranon bursitis has also been remarkably reduced.
I am most pleased.

I am sort of dismayed that this page does not contain the many many more testimonies as to how prednisone saved lives. I believe in natural healing, but I hate to see a one-sided review of anything. ALL medications, "natural" or manufactured, can have side effects. I'll take my chances with a drug that has been used safely and successfully by thousands upon thousands with minimal side effects to get relief from debilitating pain. My husband almost died from one dose of penicillin - should that drug be condemned?

I have taken prednisone for a few months for psoriatic arthritis in my neck and head. When you can't do a thing but hurt, even to the point of getting literally sick, unable to lift anything, just like grocery items, pushing the buggy, well you see how bad it is. I couldn't get a rheumy to see me on my insurance. I went back to get a shot at doctor office, but didn't even help me. Went back, and she put me temporarily 20 mg. pred. she lowered it to 10, and I am not happy with this. Says it is because it is just not good for me to be on it.

I also have to take 400 mg. of celebrex a day, tylenol too. Can someone give me some insight... I have no quality of life at all if I don't get at least 20 mg. a day, and celebrex. I am a walking pharmaceutical. I also am responsible for caring for my 20 year old that has some problems. I have to handle it all, and I only weigh at 95 lbs. She did bloodwork on me some arthritis test, and tells me my numbers, or markers aren't bad. I attribute this to all the meds I take for heavens sake. I don't wish this pain on a soul.....

My husband has been taking short low doses of Pred for 2 years. Recently he went on an 8 week high dose and 2 weeks in became withdrawn and irritable. He then told me he didn't love me anymore and moved out. We have been together for 20 years (married 13) and have 3 young children. This is so out of character and I am sure it is his medication. He is prone to depression and has never accepted his Chron's diagnosis. He doesn't talk to anyone about it.

As a hospital nurse, I was aware of many of the side effects shared here. So, when my wife came home from the dentist and with a prescription for prednisone, my first response was, 'Your not taking that."

The dentist soon called and I ran my suggestions by him. He said he has never had any problems with prescribing it to his patients. A bit further discussion and it turns out he only prescribes it 10 times a year.

I then asked why? He said for the swelling, to help with the inflammation which would reduce the pain.

On identifying myself as a former hospice and now a holistic nurse and an expert in alternative pain management, I asked if he would mind if we avoided it for the first day to see if my nursing care would help. He agreed and said that if it did not work by noon tomorrow, then start the steroids.

First, my wife took two NAC or N-acetylcysteine, a vitamin D3, milk thistle. Added to this, a few hours later she took a bonded whey protein isolate form of cysteine (about 20 grams).

By 9:30, the swelling is slightly increased but other than the sensation of pressure, there is no pain.

Additionally, she took about 1/4 teaspoon of unprocessed sea salt and dissolved it in her mouth. Then she drank 10 ounces of water. She did this again before bed.

She followed the antibiotics as prescribed.

The rationale, NAC and the cysteine both help fight inflammation and decrease the pain by producing glutathione. The steroids have been found to decrease the immune response.

The water and salt (the new CDC guidelines say its OK) helps flush out the toxins produced by the inflammation. They also help reduce the pain as well.

She is on the road to recovery. I have not found a patient in pain that could not be helped. Our bodies want to be healthy. All we need to do is give them the building blocks.

Good Health to you and yours.

When my pulmonologist prescribed prednisone for my hypersensitivity pneumonitis, I have to admit I was concerned. I'd read so many horror stories.

However, my own experience has been pretty much a non-event. I am hungry all the time, and so I've put on about ten pounds in the past month and half from consuming more calories (note: I'm six feet tall), but that's about it. My mood and energy have been great. So, aside from the weight gain, I've bucked the trend on this one.

This is my third time on prednisone. The second time, while taking the lowest possible dosage, I began having horrific psychiatric/psychological side effects. I was having panic attacks, anxiety and even once I realized it was the drug there was nothing I could do about it.

My symptoms were heart racing, numbness and tingling in extremities and face, dizziness, difficulty concentrating, shaking, etc. All the symptoms of anxiety and panic. When I had a sudden hearing loss five weeks ago and a diagnosis of cochlears hydrops or Meneire's, I was horrified to find out the treatment is high doses of prednisone. I am in my last week of tapering off and my anxiety and panic is off the charts, with all the same symptoms. Plus this time I've also had significant stomach upset and heartburn.

Great title, Deal With the Devil. For the first time today I was able to hear some tones in my affected ear but am having a hard time getting past the fact that I'm having tingling and numbness all over and can't even sit at my computer to work.

Last time it took four weeks after my last dose to clear my system and feel normal again. I hope it happens more quickly this time. Even knowing what is causing this doesn't make it any better, easier or go away.

I'm sorry to see so many people had such issues with this drug, or refusing to take it altogether. I have taken prednisone for several years now (at times prior to other medications to increase the likely hood of remission--never happened). I can honestly say, that I would rather dance with this "devil" then spend my every waking moment in pain, or fear of eating something that will set off my Crohn's.

Of course I've had side effects: I lost my teeth--breaking at the gum line, enamel wearing leading to complete extraction. Due to the high dosage I had the potential to develop anxiety attacks (totaling three in the five years I've taken it). In all, my side effects were extremely tolerable, and a fair trade given that on this drug I have a -life-. I am not ruled by pain, or being so listless I cannot do anything more then simply lay in bed.

What people are apparently not being told (a shame indeed) is that this medication has the potential to do incredible things, it can truly help (and for all intents and purposes this is truly the only drug that has ever worked for me). But that in taking it diet, exercise, and learning what symptoms you exhibit; as well as how to control them are important factors in staying healthy, and getting the full benefit of the medication while making the effects manageable.

It is sad to see the many horrible experiences most of you have had with this drug, it is even sadder still to see many of you dismissing the good points of the medication--which is why I felt the need to share -my- experience, because without prednisone I wouldn't be capable of leading the life I am. Which, given the severity of my Crohn's, with all the flares and troubles it has given me is pretty darn good! I feel like a person, a person who is happy, healthy, and most days I exhibit no sign that I have any medical condition whatsoever. Prednisone has allowed me to actually live a life (with certain dietary restrictions--Crohn's related not pred. related) that is full, and rich! I could not be more thankful for this medication!

the title says it all. no sleep can't stop moving no matter how much pain you are in. you could have a broken leg and you wont stay still.
bad thoughts, anger, and other crazy effects. the devils drug for sure.
I am slowly getting off this drug after 4 years. can't wait, but I have to. lol

I am so thankful for Prednisone - albeit nervous when I need to take it - because nothing else can clear up my asthma attacks when they get so severe that Prednisone is needed. I've had bronchitis for a month now and after only two days on Prednisone, I feel so much better. A weight has been lifted. I'll be a bit nervous for the rest of my course (9 days total) because I know that the side effects can be rough. Still, I'm so thankful to be able to take a deep breath again.

I was often placed on lower doses of Prednisone (usually around 10mg) for asthma when I was a kid. Though I'm not sure if I ever actually had asthma, I do remember what it was like being on the drug.

I don't remember having insomnia or depression, but I suffered from Cushing's Syndrome and I often got tremendously painful hypertensive migraines. I actually once went to a specialist who wrote a note to my regular doctor at the time telling him it seemed obvious that the Prednisone was causing my hypertensive migraines, and that I should be tapered off immediately.

I haven't taken this drug for about 18 years (except possibly briefly in 2002) until today. I'm rarely sick these days, but I've Strep Throat for the past 4 days (also, haven't had it in 18 years), and was given a Rx for 40mg daily for 4 days. I was told to take both 20mg pills together. No taper. I took my first dose today and I don't think I'll be taken any more. Not another mg. I feel I'm on the brink of having a migraine...which I haven't had since 2002. I'm on antibiotics for the Strep also, so I don't think I'll be taking any more Prednisone.

I'm on day 7 of a short course of Prednisone, 40mg for 5 days and then 20mg for another 5 and then done. And while I'm definitely having some weird and occasionally unpleasant side effects--the water retention and near-mania, the general cranking up of the radio dial in my brain--nothing so dreadful as what some of you have been suffering. And the condition it was prescribed for, apparently a bacterial infection of the lower intestine, was much, much worse. I'd spent four days on my back with a heating pad on my stomach, whimpering, before I finally got to the doctor, convinced that my appendix was about to blow or something equally awful.

So yes, it's making me a little weird, but I'm so relieved to be functional and pain-free after a really scary few days that I'll take the weirdness. I'm looking forward to sleeping normally again too, although it's not insomnia per se, just... lack of desire to sleep.

It's not necessarily all bad, is my point. Especially in short courses.

hey, I am 35 year old woman from Newcastle NSW Australia. I have also been diagnosed with BOOP only 6 weeks ago. I had an accident at work in May 2012, and after 3 weeks I was sore under my arm, resulting x-ray showed my lungs were a bit weird looking. a throat biopsy & a VATS in Aug 2012 & it (apparently) is BOOP> I am on 37,5mg of Prednisone & have a 6 week check 18th OCT to see if it is working.

The side effects are just starting now & I'm trying not to be overtly paranoid but haven't noticed any significant change in my breathing. As I've said, if it helps me breathe again, I'll take the side effects. The non-sleeping is just starting to become problematic. I really hope your journey ends well & the Prednisone helps the BOOP!!
Thank you so much for sharing!!

Used methylprednisolone 4mg 21 tabs over 6 days about 5 yrs ago. Had hideous side effects, the worst violent hiccups that did not cease day or night. Interfered with sleep, eating, working. Bad anxiety. I was not able to complete full weaning dosage. Adverse effects lasted about 2 - 3 weeks to subside. Fully recovered over 2 months. 5 yrs later due to inhaled irritant, I'm put on same meds and regimen. I had forgotten my previous experience. Day 1 insomnia and heart burn. Day 2 hiccups, heart burn and left ear slight hearing loss, insomnia. Day 3 hiccups that haven't subsided, muffled left ear hearing, horrible heart burn, anxiety, insomnia worsened. I then stopped the dosage without weaning after day 3. A day later I still have the worst adverse effects and seem to be getting worse instead of improving. Seems the treatment is worse than the illness. There are alternative treatments that should be considered before going with synthetic corticosteroids, which should not be first line of treatment in my opinion.

This drug, Prednisone, has been not only euphoric in the short term, but a life saver. The idea of being a mouth breather and the discomfort which comes with it, for the rest of my days, is intolerable, in short. necessary high doses from my doc, I feel like superwoman, the president, and an Olympic swimming champ all in one. I'm SO sorry for those who don't have the reaction for which this steroid is meant, I couldn't live without it for about 20% of the year. It does make it hard to sleep, but I'm one of the odd ducks who finds no issue with that, since I am 26 with no kids. It's BLISS.

SInce recently being diagnosed with an auto-immune condition very close to lupus, I have been on prednisone, 20 mg every other day. I know that many people are demonizing this drug, but the truth for me is that it has been the only thing that makes me feel human again.

I have taken the drug intermittently over the years for asthma, pneumonia and bronchial infections, with good effect. Once the symptoms of this disorder hit, I followed my rheumatologist's recommendation on dosing, and he finally agreed to the 20 mg every other day. I have had very little in the way of side effects, which must mean that I am one of those who tolerate the drug fairly well. Rather than being hyper, I feel energized again and able to do some things that I could not do when the condition was manifesting.

I also understand that cutting back and looking for dietary alternatives, stress relieving techniques and life modifications is part of the whole picture. I hope that finding different ways of dealing with my stress, diet and condition will someday allow me to wean off of Prednisone. For now, I can't even think about doing that. Remember that we are not all cut from the same mold when it comes to life and reactions to medication.

In 2000 I developed Ulcerative Coitis at age 69, lost fifteen pounds in two weeks and spent a week in hospital. Discharged into the care of a fabulous doctor, I was on a ten-week tapering course of Prednisone. Remission was total with no apparent side-effects. The colitis flared-up again in 2008 due to the stress of four month long 24/7 care of my wife after lung cancer surgery. Local doctor (Vetinary!!!) couldn't get it right and I was on the demon Prednisone for five months until deciding to go it alone. Faith worked, but now I have constant toe pain, worse at night and no apparent remedy other than removal of toes! My former brilliant doctor moved to the U.S. Wish I knew his address!!!

I had to take Prednisone after a bad allergic reaction to a typhoid vaccine (I was headed to India). I was given a very large dose, and was told to gradually taper off. During the plane ride, I started having non-stop panic attacks. It was an 18 hour flight, and all I could do was sit there. It was awful! These panic attacks lasted for another week.

I had my prescribed Ativan with me, but it did nothing to make the constant terror go away. I couldn't go to a hospital, because that is something you do not want to do when in Mumbai. I also couldn't eat anything and lost a significant amount of weight. I literally thought I was going to die. All I could do was lie there, and not sleep. It was terrifying.

I came home and started having blood sugar problems (so bad I would lose my vision). I would also wake up in the middle of the night to terrible panic attacks. It also caused me to gain a lot weight, which I have not been able to lose. It has now been a year, and I am finally getting back to normal. I get that the drug probably saved my life, but I will never take it again (unless it is a life-or-death situation). I think there needs to be more warning with this drug.

I have a family member who has repeatedly used Prednisone for many years. Her doctor prescribes it for almost every little ailment. Anytime something goes wrong, she is back on the drug. She is probably on it for 50-60% of the year.

She now has multiple other issues, which I think are caused by taking this medication. Some are so bad she now thinks she needs surgery-- what she needs is to GET OFF THIS MEDICINE!

Please, please, please research these types of medicines before taking them. I had a doctor suggest them to me for urticaria but ABSOLUTELY NOT-- I was able to finally make mine go away (after many months) by doing my own research and not blindly believing what I was told.

HI Fadedblue, I had an allergic reaction from the dye contrast for my scan, I went to the emergency room a day later, my entire body covered with bright red rashes, they gave me 5 days of 60mg prednisone, and I feel like I'm going to die, I woke this morning on day 3 and my hands and wrists and ankles and feet are swollen and in severe pain, I went to the doctor she told me she thinks this is from the high dose of prednisone but she can't be for sure and I have to finish the med just taper it down.

I hope you are feeling better and if anyone has experienced the same symptoms please tell me what you did and how you are doing all she told me to do was take tylenol and it will take 2 days to start going away after I stop the prednisone.

Four months ago I woke up and had half of my vision missing in my left eye. I called the local eye department at the hospital and they said my optic nerve had completely swollen and that had effected my central Vision. They said it would come back and the put me on 80mg of prednisone and vision never returned so taped dose down.

Then 3 days later I had a relapse causing more vision loss so was out back onto prednisone but 120mg this time. My face and neck swelled like nothing, I couldn't sleep, gained weight and stretch marks and also gained an intolerance to lactose and dairy which is linked into this drug.

I am a 23year old woman who gets married in 6 weeks. As they are not 100% sure what is causing my optic nerve to swell or if the prednisone is helping (it's been over 5 months) I was very keen to come off the drug before more irreversible damage is done to my body and in time for the swelling to go down before my wedding my doctor told me that 'it sucks to be you'. So it's a waiting game now to see what's going to happen when I taper off this dose, bone scan this week to see if any damage has happened to my bones.

It also doesn't help that the doctor is not aware of side effects of this drug. If anyone has come across issues with dairy or lactose while taking prednisone I would love to know.

I was prescribed prednisolone whilst on a recent trip to the UK where I picked up a fairly severe chest infection. The dosage was 8 x 5mg tablets (at the same time) over 9 days. I was not told to taper the dose or given any other information. Upon my return to Greece I checked with my local pharmacist about tapering the dose and was told this must be done. I have just finished the medication and feel awful. I am experiencing dizziness/vertigo, headaches, muscle weakness and had I not seen all the information on the web about this wretched drug, would have thought I had some fatal illness. If I am experiencing this feeling of general malaise after a relatively low/short dose, goodness knows what happens to a person's body after being on the drug for much longer.

I am on the same meds right now. I am glad I found this site. I thought I was crazy, could not breath, tight chest and throat, heart beating out of my chest, ears ringing, cough my lungs out dealing with pneumonia and COPD. I hope it works for most, but I will not take it again.

Don't ever want to go thru that again.

I had a allergic contact dermatitis (bad chemical burn rash) on my hand with exam gloves. No patch test was done so I asked my worker's comp doctor to send me for it. She didn't. My doctor prescribed topical steroid, antibiotics and allergy polls. I was on them along with topical steroid as needed for two weeks. In the third week after my work, another rash appeared on my both legs. I was having sharp needle pain in my arm, shoulders and legs with it.

I was puzzled how I got them because I was not using the exam gloves that I thought I was allergic to anymore. My worker's comp doctor told me that rash on my kegs was not work related, I couldn't understand that either why I was having rash on my legs. So I was almost believed what my worker's comp doctor told me. Without certain ideas why I had more rash on my legs, I went to er and checked them up since my rash was not improving with topical steroid. Itch on my both hands and legs were was unbearable.

I asked if my rash was allergic reaction from the medications I was on for two weeks for my allergic contact dermatitis, he said, not likely so, he said, it looked like a bug bite and stop topical steroid and allergy pills and antibiotics. He said start taking by oral prednisone. I started taking only oral steroid, prednisone 60mg for 3 days, then 50mg for 3 days.

The first three days I couldn't sleep, always nervous. My heart was beating like crazy, I was feeling so tired but alert. I gained 10lb, I was sad, I was sick, I was depressed so badly, my experience of the day 4 with prednisone was even unbelievable, I was peeing all the time, say. Less than one hour. A lot of amount. I felt thirsty and had a lot of water, and I was going to bathroom all day all night. I was sweating all day all night. I started having chest pain along with the same sharp pain and felt chill on my legs and both legs were also painful.

I called the work comp. doctor. She told me to call ambulance because she was concerned my condition and asked me question if I had blisters in my mouth, I said no, but I realized that I actually had a blister on the right inner my mouth. She asked me to stop talking prednisone and prescribed different kind of allergy pills instead, my symptoms staid the same for a couple of days after I stopped oral prednisone.

I lost the 10lb right away and still urinating more than usual another 3 days after that. I checked my weight because I had no appetite but I ate some for keeping me going. My doctor asked me to go get my blood tested so I did. The red flag was for my glucose level and also my bum level, they are elevated moderately, also, my rdw was elevated. I lost 6 more pounds. I felt fatigued and hot flash with low body temperature for the day, but when I went to see my doctor the next day, my body temperature was 99f. My normal temp was usually less than 97f. For me it was high enough. Also I was still having chest pain and I was drowsy.

I went back to work following over night shift. I felt shaky and dizzy during work, and started feeling little better on the next day. I was fine but tired the day after my work but I was fine compared to the day I stopped prednisone, but by the evening in the day, I started feeling cold and feel so sick, I checked my temperature! It was 101f. I couldn't go back to work that night.

I was wondering why I was so sick since after I started taking all meds, later found out interesting article that said, if I was allergic to topical steroid, it is possible to make more rash anywhere on my body. Ohhhh nooooo!!! Please, someone tell me, am I allergic to steroid in any route? Well, my worker's comp doctor dismissed me because I had rash on my legs. Yeah, I know I don't wear exam gloves on my legs for sure.

This entire experience puzzles me why no one did patch test for me to check what I was allergic to? They just diagnosed me and have me prescription, then once they run out their knowledge, they brutally dismissed from their care. Don't you think it was medical malpractice? I do think so.

I am on prednisone for uveitis. 2 months at 80mg now down to 60mg for the next month. I live in constant fear of breaking bones or dying of infection. I will eventually see a rheumatologist to hopefully get on a steroid-sparing agent.

I was just put on prednisone (along with a z-pack and erythromycin) for pink eye and an inflammation in my ear with fluid behind it. The ear pain had started on a Friday, but I didn't go to the doctor until Wednesday, as it seemed to be getting better on its own. I went to the doctor for the pink eye, purely because I know how contagious that can be. I mentioned the ear, he checked it out and prescribed 20mg of prednisone for 5 days. The pharmacist warned me about possible side effects, but in a joking way that made me think it would be irritating, but nothing all that horrible.

I took the 20mg on the first day and was thrilled for the first 10 hours to feel no change whatsoever in my moods or anxiety/energy level. I even felt pretty sleepy when I went to bed. But at 2am, my eyes literally popped open on their own and I could not go back to sleep. It felt like someone had filled my left shoulder/arm with cement, and my thighs felt as though I'd run a marathon. In addition, I had a headache that was incredibly painful. I tried to accept that it was just what I needed to go through to take care of myself...

I came into work and tried to walk to lunch with one of my co-workers, when my left leg literally gave out. I couldn't put any weight on it whatsoever. It was the worst charlie horse I've ever had. This went on for over an hour, and may still be going on -- I've just stayed seated since that time, so who knows what will happen when I stand up again.

I talked to my sister-in-law who is a nurse, and she recommended that, if it wasn't a life & death situation, I may want to consider weaning myself off of it, as it is dangerous to stop taking it cold-turkey. She suggested I take just 5mg today and then be done with it. Neither my doctor nor the pharmacist had told me anything about lowering the dosage during the five days I was supposed to take it, but from everything I've heard, it's really not a good idea to take such a high dose for the full 5 days for such a minor problem as an ear inflammation. I had no hearing loss, I wasn't even having pain anymore.

I don't blame my doctor -- I'd rather have someone who is aggressive in treatment than someone who doesn't do anything. But by the same token, the medical field really needs to get on the same page where this drug is concerned. Unless it's a matter of life and death, or a serious quality of life issue were I not to take it, I would not ever take it again.

Before I was given a prescription for prednisone over 15 years ago, I had never had an anxiety attack. I have lived with high levels of anxiety ever since taking prednisone. Has anyone else had this experience?

I am trying to find any research on prescription corticosteroids possibly contributing to a dysregulation of cortisol levels (in humans or in animals).

I have an opposing viewpoint. While Prednisone has short and long-term side effects, it can also be a gift for those with colitis, uncontrolled asthma, and other types of inflammation. I take it for medical issues I don't wish to detail online (yes I've been to many doctors and tried everything else). When I don't take Prednisone, I'm sometimes so ill as to be bedridden. With it, I can feel close to normal.

Like every reasonable person, I try to minimize the dosage and frequency. With doses over 10 mg I get mild insomnia and overeat, but that's it. It also makes me feel healthy and energetic. A family member took it short-term for poison ivy and experienced no side effects. So not everyone is miserable on it.

Some people are very judgmental about those who need Prednisone. Without Prednisone I wouldn't be able to work, travel, or exercise. I'm not happy about taking any medications, and it shouldn't be taken lightly, but sometimes there aren't better options. Obviously everyone should do their homework before taking any medication, including so-called "alternative" meds, and get second opinions. But it's often a balancing act of the risks and benefits. I'm ashamed to admit I used to be one of those people who second-guessed others who took strong medications for serious medical problems. Not any more.

I have been on prednisone for nearly 9 months now - started on 60mg per day and I'm only down to 30mg - after being diagnosed with a rare disease called Takayasu's Arteritis. I am also on Methotrexate so that it will take over the role of the steroids when I'm finally off them.

However I'm nearly at my wit's end after taking them for so long - I've gained a lot of weight (20kgs, gone up 3-4 dress sizes), have a huge moon face, my skin is terrible, I'm moody & emotional, the list goes on! Lately I've gotten really stiff in my legs though, which I can only put down to the fluid retention. And for the past week I've had sharp shooting back pain - has anyone else had this?

Everyone tells me that prednisone should actually cause the opposite, but nothing has changed so that's all I can put it down to. I'm thinking it's because of the excess weight - I can never really get comfortable, it would be putting a strain on my body, and I don't sleep very well.

At this stage it looks like I won't be off prednisone completely for another 3 months which really has me worried. I don't know how long I can keep going like this as I actually feel like I'm getting worse. Can anyone relate? I would love to know when I might start feeling a bit more normal, and how long the side effects take to go away once I'm off the prednisone.

Hi Jo
It sounds like something very similar happened to me recently, but my treatment was very different. I woke up and the sight in my left eye was very blurred in the centre, like a finger smudge across it. After many tests I was diagnosed with optic neuritis (inflamed optic nerve). I was treated immediately for 3 days of very high dosage prednisone administered intravenously (1000mg per day), then treatment stopped completely. By the 2nd day of treatment my sight was much better, and now (1 month later) it is almost completely back to normal. I felt pretty bad from the high dose of prednisone, but the effects only lasted for a week. Now I'm fine, back to work and sight is good.
I have been told this might be the first symptom of MS, but my MRI scans were clear so I have not been diagnosed with this and hopefully won't develop it.
AS

I was put on the oral form of prednisone about nine months ago it started out ok the most bothersome for me was constipation which I suffer from anyway but as I increased to 80mg a day everything started to go to hell. The constipation got so bad I wouldn't eat it seemed everything backed me up I had acid reflux and heartburn terrible stomach cramps and ended up crying and calling the doctor and told him I couldn't do it anymore, he immediately started to wean me off but it was slow going I was still miserable so he had me taper down faster and had since been referred to another hospital.

The doctors still have me tapering, down to 4 1 mg tablets a day and I taper down every week until I am off. He started me on an IV prednisone only have two days of that in now but he knew I had to to get off the oral form he said my body was clearly rejecting it and his hopes that with the IV treatment it being fed directly into my veins instead of having to be digested and go through the whole digestive process still have the weight gain and insomnia my face is still puffy full and square. I think I look like fat bastard from Austin powers. My face is normally thin with high cheek bones and not sure I have cheek bones anymore. I feel terrible for you the weaning off is such a slow process.

Why did they put you on this, have you thought about switching doctors? Personally I think prednisone is over or mis prescribed and the one drug the doctors turn to when they are stumped. I am very pleased with not only switching hospitals but my doctors too.

I would just like to say to everyone... THANK YOU ALL!! I was just prescribed a 4 day dose of Prednisone 20mg for an upper respiratory infection. I was given 3 pills of Prednisone not sure if they were each 40mg Prednisone or 40mg in total before being discharged from the emergency room. I left and went to the pharmacy to have prescription filled and thought it was just in my head but I kept feeling this prickly stinging sensation under my skin on my right shoulder.

I also noticed that my skin felt cool and clammy yet I was rather warm. I initially brushed it off as my body adjusting to the tylenol w/codeine I was given for pain. After I got home, I was laying in my bed and the muscles in the back of my thighs kept twitching uncontrollably.... eventually it stopped. I was supposed to start taking my prescriptions last night but I never take any meds at night if I was given meds at the hospital within 6 hours of my bed time. I usually will wait and start fresh the next morning.

I woke up this morning feeling like my clothes were damp and still sweating. I am taking these pills back to the pharmacy and demand a refund. So glad I read everyone's comments.

I took prednisone for 1 week. I don't know why I blindly obeyed my doctor! never again!!!!
worst week ever! horrible headache everyday, very bad mood, followed by heart rate increase! and severe abdominal pain and nausea. He could have just told me to take more ibuprofen!!! I will ALWAYS do my research beforehand from now on!!!

I'm going through a similar situation. How long until the side effects of prednisone go away? Do you recover your muscle tone? How long was it for you to be right? How has your skin recovered? Regards

Hi Mary, I am experiencing the same problems you had... I was prescribed prednisone for an sinus infection... Additionally, I have shakes and tremors and can not sleep at all. I consumed only (3) 20mg gram pills. How long did these conditions last for you is my question to you?

It is amazing to read here that people taking Prednisone are not told to taper over a verrrryy long period of time. Anything less will have dismal effects on your body. Your adrenal glands do not produce naturally while you are on pred, and the pred must be tapered VERRRYYY slowly to allow the adrenals to kick back into production. Take it easy on the reduction. Like 1 mg a week tops. My own body does not like the reduction and I get GI problems for a day. Get more pred if you need to to help the slow taper, it is cheap. Take it in the morning after a meal. It is an upper so you will not sleep if you take it at night. You can take Tylenol for pain while on Pred.

Prednisone for me has been a miracle life saving drug. I am 73, was diagnosed with severe RA 6 years ago. The next two years all of the standard RA drugs were tried with minimal control of my joint pain and swelling. A biologic drug was Rx. After 3 doses, I developed sudden onset of shortness of breath and a heart rate of 140 per minute. Interstitial Lung Disease was diagnosed... possibly caused by methotrexate, the biologic drug or? I received 50 mg of prednisone daily for close to 9 months, (every time a tapering was tried my heart rate shot up).

It was gradually tapered down to 10 mg a day. I also received cyclophosphamide for two years. The treatment worked, my last Lung CT scan revealed no progression of the ILD. I have continued on 10 mg prednisone daily for control of RA since I have had an adverse reaction to all other DMARDs. I will probably be on it forever! I take it every morning with a big bowl of oatmeal... never had any GI upset. Yes, I developed prednisone induced cataracts, glaucoma, osteoporosis, a moon face, buffalo hump, insomnia, some weight gain, that said... it sure beats the alternative!!! Thank you Prednisone. I am grateful to be so well.

Alex,

My teen son was given a high dose of steroids for 3 days (1000mg = 1g) in order to reset the body from an autoimmune disease. Now he is on a gradual taper dose (20mg twice a day). It is day 4 from when the high dose ended and I can tell you that the side effects he is experiencing are: sore muscles and weakness (he has a hard time picking up a full 1-gal water jug), has a hard time getting out of bed, extreme fatigue & slowness. It takes a lot of effort for him to get off the couch or to get in the car.

Is it normal to feel this way after such treatment? I just hope and pray it is the road to recovery.

I would appreciate your input. Thanks

Although, I am here because I'm considering Pred for ear and skin condition. I saw your comment and wanted to inform you that possibly it is not the pred that has caused your side effects - it may be the Ciprofloxacin or a combination of both.

Twice I experienced psychotic grief episodes when given Ciprofloxacin following a test procedure. I looked up Ciprofloxacin and found that others have had this side effect too. Mind you it was not a minor grief episode, it was deep grief as if someone near and dear had passed away. I will not take Ciprofloxacin ever again! Also, Ciprofloxacin can cause chronic joint issues too.

Have twice taken prednisone for pretty severe bronchitis and no trouble at all! I get a little jumpy, but I still sleep well and am do just fine. Helped with the bronchitis (along w/ a Z Pack). Tapered off no worries. No left over side effects.

Now, if I had to take this long term I'd be much less sanguine, but the 3 to 5 day course isn't really a big deal and helped a lot. Just take it with food. It's hard on the stomach and tastes really lousy.

Many drugs have side effects. You need to balance the risks and "rewards" of any drug. As I said, for short term this drug hasn't done anything bad to me.

OMG my mother has bipolar and was taken off her med for this 2 months ago in the local ER. She had been stable on it for 2 years. We watched her like a hawk, and low and behold she also got diagnosed with recent temporal arteritis and was started on prednisone 60 mg per day x 1 month to titrate by 10 mg every month. She was on the 50 mg per day and had been erratically cleaning her home and throwing things out, when she started to experience severe confusion.

At lst we thought mini stroke, until I realized it could be the prednisone., the drs really didn't want to hear this. She stayed 12 hrs in the ER with no help and was sent home after trying to blow her nose on a slice of cheese!! 5 hrs later she experienced 7 grand mal seizures!! Back to the ER we went. She got transferred to a better hospital and got good care but developed double aspirational pneumonia on top of it all, and of course tx of choice is prednisone.

The md's don't want to deal with taper down dose an constantly pass the buck. She was transferred to a rehab facility today for weakness and no one has started titration until I called MD tonite. I am only a nurse but have enough common sense to understand the outcome of this horrific drug if proper protocol not followed!! She may never regain her old self, but we can only hope and pray she does!

I'm 63 years old and was diagnosed with tempura arthritis, which if left without treatment could cause a stroke and/or blindness. My doctor started me at 80 mg of prednisone and gave me a tapering schedule that lasted 12 months. Ten months later I'm down to 1 mg per day for 30 more days and 1/2 mg for another 30 days. The prednisone cured my illness within 2 months but I didn't sleep much for the first 6 months. The initial side effects I had were lack of sleep, erratic fast heart beat shakiness and weight gain.

The side effects changed as I reduced the dosage. I went from not being able to sleep to not being able to get enough sleep. I still lack energy and generally don't feel like going anything all day, which is so unlike me. I wake up with a headache feeling like I was on a drinking binge the night before and it takes me a couple of hours before I can attempt to do anything that involves me getting off the couch. The shape of my face changed and I have had skin problems that I haven't had since I was a teen. I feel like I have lost a year out of my life, however, it was still worth taking the prednisone given the potential consequences of doing nothing.

Your doctor should also be prescribing Risedronate if you are on a high dose of Prednisone. Prednisone weakens your bones and the Risedronate helps to prevent this.

I was prescribed 30 mg a day for 5 days. I take it 15mg twice a day.Not told to taper. I have 30mg left. Should I taper that over the next 2 days. I have only taken 15mg today but am starting to feel very dizzy and very edgy. It was prescribed for severe bronchitis and breathing problem. This is a pretty short term dose so hopefully I wont have bad after effects.

Prednisone is the drug from hell. I wish I would have researched this drug before ever taking it. Yes, has it helped me for what it was prescribed, but way too many side effects for me to deal with. Your doctor should tell you ALL the side effects you are going to experience BEFORE you take it. I have never, ever experienced anything like this in my life AND I do not ever want to....as we all know all medicine has side effects, however this is the worst medicine I have ever taken in my life!!!! And, now to think CHEMO is needed to get me off this medicine, which again I was not told before I started taking it.

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