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Amlodipine (Norvasc) Side Effects

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For reasons that remain somewhat mysterious to us, amlodipine (Norvasc) is one of the most popular blood pressure medications in the pharmacy. This calcium channel blocker lowers blood pressure in part by interfering with the flow of calcium into artery walls. This helps dilate blood vessels in the heart and throughout the body.

Possible side effects associated with amlodipine include:

• Swollen ankles
• Fluid retention
• Dizziness
• Headache
• Flushing
• Fatigue
• Nausea
• Palpitations
• Peripheral neuropathy
• Skin rash

A fascinating study called ALLHAT (Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial) involving over 33,000 participants revealed some curious data. An inexpensive diuretic called chlorthalidone was just as effective as pricier drugs like lisinopril (Prinivil or Zestril) or amlodipine (Norvasc) when it came to reducing complications of hypertension such as kidney or cardiovascular problems. More important, however, this diuretic was better able to prevent heart failure (Archives of Internal Medicine, May, 2009).

Heart failure is a very serious condition. Elizabeth Taylor just died from congestive heart failure and it is a difficult disease to treat. Because calcium channel blockers like amlodipine have been linked to a higher risk of heart failure (American Heart Journal, Jan, 2007), than diuretics like chlorthalidone, we think patients should be warned about this potential complication and other side effects associated with this medication.

One other word of caution. An article in the Canadian Medical Association Journal (Feb. 22, 2011) has reported that when calcium channel blockers like amlodipine are combined with certain antibiotics such as erythromycin (E-Mycin) or clarithromycin (Biaxin) that the result can be a precipitous drop in blood pressure. This is particularly problematic for older people as it can cause serious dizziness or shock and lead to some very dangerous cardiovascular complications.

Below you will find reports from visitors to this website. Feel free to add your own experience (positive or negative) with regards to amlodipine.

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Paul43, March 22, 1011:

I take amlodipine (Norvasc) and always have bouts of drowsiness. Is there another high blood pressure medication out there that would replace amlodipine without the drowsiness or do all blood pressure drugs cause drowsiness?
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Vicki S, Feb. 20, 2010:

I have always had a problem with any kind of medicine since I was young. I am now on only two medicines for BP: atenolol and amlodipine. I suffer severe headaches and debilitating flu like symptoms without the muscle aches. I experience dizziness to the point of being immobile.

No doctor seems concerned or able to find anything to help. They just don't want to deal with it. How dangerous are these side effects and what should I do?

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Tyler, Oct. 26, 2010:

On my doctor's advice I took 10mg of amlodipine (Norvasc) along with Carvedilol for about a year to control high blood pressure. I am otherwise healthy.

After my feet began swelling, I put up with it for as long as I could, but stopped when it became too painful to walk. So I called my doctor and told his nurse that I was stopping the two drugs, and asked if there was something else I could take.

They called back and scheduled an appointment. When I saw the doctor a few days later, he said he would not prescribe a new drug at that time. HE NEVER MENTIONED ANY POSSIBLE PROBLEM FROM ABRUPTLY STOPPING THE AMLODIPINE. About 10 days later I developed extreme "rebound hypertension," with BP soaring to as high as 220 over 118.

Two weeks later, I am STILL struggling with high hypertension!! These doctors cause more problems than they solve by failing to give patients the info they need to make intelligent health decisions. Had I been warned, I would NOT have stopped the drugs abruptly, but sought advice on how to wean myself off of them.

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Janice, June 25, 2009:
I have been taking many medicines for my blood pressure. Currently I am taking Metoprolol ER Succinate (100 MG), Diovan (320 MG), Hydroclorothiazide (12.5 MG), Levothyroxine (0.05 MG), and Amoldopine Besylate (5 MG) for my blood pressure.

My problem is that recently the Amoldopine Besylate was added. I have been smelling cigarette smoke which is not there.

I thought maybe I was going crazy until I went on the internet and saw that someone else was having the same senses, but it was with a different medicine. I would like to know if any of my medicines are causing this. It is weird. I work in a smoke free environment, yet I walk into the doctors offices and smell smoke and I am the only one smelling it.

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Jimmybw, Jan. 23, 2011:
Interesting. I noticed the past two years that my feet get really cold at night. I never linked it to my medications. I checked with my Doctor, and he believed it could be a side effect of the Amlodipine. In fact, he was having the same issue with the drug.

What caught my eye here was the comment about smelling cigarette smoke. I've noticed it as well. I thought someone may have been outside my home smoking, but never saw anyone.

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SW, Oct, 2007:
I have taken Norvasc for 15 years without any problems. The new generic Amlodipine Besylate caused me to have every side effect listed, headache, dizziness, nausea and swelling of the feet and ankles. Unfortunately since there is now a generic available the cost of Norvasc is sky high.

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You did not mention that a persistent dry cough is also associated with Norvasc and similar drugs. My former doctor only prescribed more medicine to rid me of the dreadful, annoying cough. When I realized I felt worse for all the meds, I quit them all and changed to a doctor that wasn't a pill-pusher. There are some wonderful older simpler meds available, but the docs get lots of samples so they go with the flow.

My doctor prescribed Norvasc to replace the Quinapril I had been taking because she was concerned about kidney effects. Within a week of starting it, I was so depressed I could not function. I took myself off of it and went back on the Quinapril until I could get in to see the doctor.

Taking Cozaar now with no problems. There are quite a few online reports of depression with this medication and I think physicians should take these complaints more seriously. I am reasonably healthy emotionally with some seasonal affective disorder, but this medication made me feel as though life was not worth living. I have never had such a reaction to any drug and feel this is a serious enough side effect that physicians should monitor its use carefully.

I have taken norvasc or the generic for a few years now. No side effects!!!

The Dr's found that only norvasc could lower my blood pressure.

I would like others to consider the fact that if you are a small framed women, you should insist on the Dr. using a smaller(child size) cuff when checking your blood pressure... it will make a big difference in your reading. In order to have eye surgery I had to go to a "Doctor" to approve of my having eye surgery... after all he was putting his reputation on the line. He gave me several medications... most likely to protect his signature.... a nurse told me that my readings were normal, but the Doctor insisted on using "his" cuff which covered my entire arm!

My bp was much higher than the nurses reading using the smaller cuff minutes before. I got off the meds as soon as my surgery was over... Eat dark chocolate-celery- all of those recommended dietary helps!

Are there possible adverse reactions from combining amlodipine with a calcium channel blocker like olmesartan, the fixed-dose combination I'm now taking with Azor 10-40MG? Previously, I was on Benicar, and it was far less expensive. It would seem from your update from the ALLHAT study that I could replace amlodipine with Benicar's hydrchlorothiazide to stay stabilized at stage 1 hypertension (149/70).

PEOPLE'S PHARMACY RESPONSE: WE DON'T DISAGREE, BUT THINK YOU SHOULD TALK THIS OVER WITH YOUR DOCTOR.

I take amlodipine, benazapril, and lasix. I do experience ankle swelling, but I did not really notice it until after I developed Atrial Fibrillation. That was when the diuretic was added. When my BP was not quite in control, my doctor warned me about ankle swelling and increased the benazapril instead which did the trick.

The one nice side effect from norvasc (amlodipine) has been the cessation of migraine headaches for going on 15 years. I think on my next visit to my doctor I will discuss this article and changing what I take for blood pressure control. If the migraines returned I could always go back on norvasc perhaps in a lower dosage.

I was taking 25 mg. Atenolol and 2.5mg. Amlodipine for high blood pressure for a year but my blood pressure increased so the Doctor said to take a whole Amlodipine (5 mg). After two weeks the pressure came down but I have swollen ankles, lightheadedness, headache, flushing and fast heartbeat - at times.

Why is it Doctors will not believe these meds cause problems and, instead, send someone for a CT scan of the brain to see if there may be mini strokes instead - even though his patient is healthy otherwise???
B. C. March 25, 2011

I started out 7-8 yrs ago on lotrel 5/20, but after a few yrs I was put (by our prescription service!) on the generic: amlodipine/benazapril. I've had no particular problems. Now my normal BP is +/- 123/80 or so. I do have the intermittent cough, but I think that's about it.

I agree with Pauline. I have been on Norvasc or it's generic for more than ten years, and have no side effects. I guess we are all different in how we react to drugs.

Leave a comment?? After reading the posts for this article I am truly near being stunned. If these medications can create such serious results and side-effects and the prescribing doctors seem to be the blind leading the blind and pulling a shot-in-the-dark, where is a person left with what alternatives?

Are there any natural resources and resources to replace these medications?? Some - no, make that mucho more - information is seriously needed.

Norvasc at 5 mg rarely causing swelling, probable less than 5% but at 10 mg its very common up to 25 %. It would be very unlikely that norvasc would cause cold feet as I commnly Rx this drug for that very reason in people who have Raynauds. Swelling with Norvasc is much less, when it is combined with either an Ace Inb. or Arb. Cough is usually caused by an Ace inb. in up to 20% of people (not with Norvasc).

I have not seen any post as to the problems I have had with BP Meds and I have had plenty. What I have experience is severe palpitations and skipped beats. And I mean severe. My heart would flutter after every breath. I thought I was going to die with Dursban.

The problems ususlly started after I was on the meds for about thirty days and took about a week to return to normal after stopping the med.
The meds that caused the problems were, Norvasc, Zestril, Lotril, Dursban, and I think some others.

I had been on Verapamil for years but it gradually stopped working. Thankfully, I found a heart doctor that listened to me and put me on Acebutolol. I seem to be fine now.

Thank you

I was taking Benicar without any side effects but my insurance will no longer pay for it. I am now taking Losartan (generic for Hyzaar)) I also take Amlodipine Besylate 10 MG (Norvasc) without any side effects.

My medication for diabetics has changed from Metformin to Actos 5mg. I have experienced some fluid retention in the ankle since taking that. One of the side effects from that says that it may cause swelling.

I am currently taking Atenolol 50mg, Lisinopril 40mg daly, Felodipine ER 10mg (eod) and Hydrochlorothiazide (eod) to manage my BP which seems to be creeping up to average 145/75. I generally don't experience any edema and usually notice that my BP drops after about 30 min of aerobic exercise. My main issues are tinnitus and insomnia going back some years. I have been taking 1/2 of a 25mg tab of Doxylamine Succinate that seems to help with the insomnia.

Question: My cardiologist does not want to change my meds since BP is more or less stable. My BP is usually elevated in the morning and drops by late afternoon.
I think these are a lot of meds. I should mention that I take CoQ-10 200mg Ubiquinone daily plus other supplements.

After reading about the problem with calcium channel blockers, since I take Calcium Citrate for Osteopenia does that lessen the danger of congestive heart failure?

I took a total of ten different blood pressure meds with varied side effects including severe constipation until my niece, a Dr. of pharmacology, suggested Diovan which has worked well for me.

Amlodipine had side effects on me like losing balance while in standing position.

My doctor substituted Lasartan for Amlodipine.

I have been taking Lasartan since last one year. I am ok with it, with no side effects.

I never heard before that Norvasc can cause peripheral neuropathy. I developed this very painful condition shortly after starting Norvasc 5 mg, but my doctors all say Norvasc cannot cause this. Does anyone have a medical reference for this side effect?

This was a very informative article. It really shows how you really need to be an informed Patient. I have been on Norvasc for 3 years. My Dr lowered the dosage when my legs started to swell. (I told him I thought it was the Norvasc.) He lowered it again when the swelling did not go down. I still have swelling and dizzy spells and nausea. I am going to ask him to take me off of it. I also take Nadolol (a Beta Blocker.) I have heard that their can be problems when taking a Beta Blocker and a Calcium Chanel Blockers like Norvasc. If anyone has info about this, please let me know.

I am taking daily Amlodipine 5 mg, hydrochlorothyazide (HCTZ) 12.5 mg, Benazepril 40 mg and Atenolol 50 mg to keep my blood pressure under control. I also have urinary frequency and have seen a urologist for eight years and have tried every drug and treatment in the book for urinary frequency and urgency (I do not have an enlarged prostate.) So, b/c I have to urinate often I do not like to take diuretics but the HCTZ at 12.5 mg is half what I had been taking and my urinary symptoms are somewhat 'under control' though I am also taking Toviaz 8 mg for my bladder.

Got any recommendations for getting off the Amlodipine perhaps?

I guess I'll have to discuss the contents of this article with my GP.

Do you still have those feelings of unsteadiness? I took Norvasc for 5 days and became dizzy and had palpitations. I have been off the drug for 5 weeks and still have dizziness, brain fog and unsteadiness, but no palpitations.

I have never had problems with high sugar readings until the doctor put me on Norvasc. After having high readings for several years she told me that she was going to start treating me for diabetes. I read an article about Norvasc causing high sugar readings and discussed this with her. She refused to listen and would not change the Norvasc.

I changed physicians and found one that would listen to me. She immediately changed my blood pressure meds and my glucose tests have been great every time. That was two years ago. If I had not trusted my instincts I would be on meds for diabetes right now and being treated for something that I don't have.

A larger cuff should make your blood pressure artificially LOW not HIGH. Using a too-small cuff is a mistake a lot of people make (more common than using a too-large cuff.

To SW:
I, too, had a bad reaction to the generic Norvasc and had to go back on the brand name Norvasc. You are so right about how expensive the brand name Norvasc became. My solution was to begin getting my Norvasc from Canada. It cost me 1/3 of the price charged in the USA. I have had no problem receiving my medication. As I lived in Canada at one time, I am only sorry so many Americans have been unnecessarily frightened by those who want to keep our health system as it is. When is the last time a doctor made a house call for your sick child, dressed in a suit at 10:00 pm on a Sunday night? Enough said.

I've been taking Norvasc for a few years and it initially caused some swelling in my feet which went away after a few weeks. Just recently my ankles have been swelling pretty badly. Has anyone experienced this effect after somewhat long term use? Should I be concerned about other causes? I also take low dose Atenolol.

PEOPLE'S PHARMACY RESPONSE: SWOLLEN FEET AND LEGS IS A PRETTY COMMON SIDE EFFECT OF NORVASC.

I had to stop taking 5 mg Norvasc (generic variety) 3 weeks after initiating the meds because of palpitations and much higher pulse rate.

Fortunately I was able to convince my doctor that I should stop it. However, after 10 days, I still experienced mild palpitations in the afternoon on exertion or when the weather was hot.

Is this normal? How long does it take to completely clear the drug?

Another question is rebound hypertension caused by Norvasc stoppage. So far I haven't seen any, but wonder if the rebound effect could come much later?

Any information would be greatly appreciated!

I had intended to ask what foods could be recommended for a blood-pressure lowering effect. I then thought to refer to my 2006 Graedon's 'Best Choices from The People's Pharmacy'. I no longer need to ask the question and at the risk of appearing a shill for the book it might be a good idea to obtain it for those with blood pressure problems. Check your local library - I just checked and discovered mine carries the book.

And at the risk of appearing really dumb, after reading the section on blood pressure and recommended foods I remembered "Oh, yeah, that's why I started eating..."

I started norvas three years ago and found I had to take it in the evening to avoid having an upset stomach. My last refill from costco's had a label saying it was a new generic supplier " greenstone ltd. The pill was bigger, about double the size I had been taking. I ended up in the emergency room because the pill burned all the way down and other symptoms. While I wait the return of my doctor from vacation I'm cutting the pill in quarters but still have a horrible sensation of clogged up throat.

I've been on Amlodipine, Atenelol for awhile now and have experienced swollen ankles. Recently, my Cardiologist upped the dosage (doubled it) and since then it's like walking around with two sprained ankles. I even had blood vessels pop around my ankle like a ankle bracelet. I tried stopping the meds for a day or two but my blood pressure went up. I've cut the pills in half and that seems to work out. I think I need to check with my dr. for a new med.

My grandmother used to take amlodipine 2.5 mg, benazepril 10 mg, atenolol 50 mg spironolactone 25 mg and furosemide 40 mg. She was in the hospital and her meds were changed to amlodipine 5 mg and metoprolol 25 mg. It has been almost 4 months and she has been having episodes of severe coughing several times a day. It also makes her eyes water and her nose run.

Should she try going back to the original dosage of amlodipine and atenolol to try getting rid of the cough? She also has swelling in her legs and is having an attack of gout in her hand and toe.

I do not believe generics are - to quote Drs. - the same. Since when is a copy exactly the same as the original?? If they are the same, why doesn't the Pharma company lower their price of, say, Norvasc to match the generic? They would sell more and, thus, pay for their research into this drug. Mr. Graedon, I respect you both so much so would appreciate your comments, as well as comments from other folks. Thank you.

I have had to take various types of BP meds over the last 25 years because after a while, they didn't seem to work. Other than great difficulty controlling BP, I have no other health problems and am very healthy and active. My cardiologist put me on 5mg of amlodipine last year and I had every symptom listed, but the worst were severe heart palpitations, flushing and hot flashes that were almost debilitating.....my clothes were soaked especially at night (I am pasted having menopausal symptoms).

I tried to give it some time, but after six months, my life was beginning to really be effected by little sleep and depression, so I cut the dose in half and noticed a dramatic improvement of all symptoms. My doctor eventually switched medicines on my next visit. I wished I hadn't waited so long to ask for a change, as it took another 3 months to feel normal again! All said and done, I figured I lost a year of my life due to the affects of amlodipine!

I take amlodine and I get dizzy. But its only when I lay down and then try to get back up I am so scared.

I am taking amlodopine 7.5mg and am experiencing muscle cramps especially at night in my legs and feet. I have read that cramps are a possible side effect of using diuretic drugs that treat high blood pressure. Calcium and magnesium are suggested supplements to combat the cramps. Should I take Calcium supplements or will that compromise the benefits of amlodopine?

People's Pharmacy response: It is OK to take a calcium supplement even though you are on amlodipine. Don't forget to take at least half as much magnesium as calcium.

I didn't even realize I had hbp until 6 months ago after a routine blood test.The first meds I was put on liposil gave me a hacking cough so bad it would make me gag. I returned to docs where I saw another GP. She then put me on to amlodipine but not before I was weened off liposil I take 10mg and the cough has gone.

I have suffered with weight gain which I can do without and slightly swollen ankles and hands and extreme tiredness and loss of sex drive but the worse thing is the racing heart. This got so extreme I actually thought I was going to have a heart attack and went back to the GP my blood pressure was fine but she referred me to the cardiology department.

I had to wear a monitor for 1 week and try to catch the episodes but most of them woke me up at night so I missed them.They were analyzed and some were actually off the chart but they said my heart is fine but I cannot understand this and I am going back to my GP again next week as all I can think of is its the amlodipine.

I had been on Amlodipine for quite some time, it regulated my blood pressure very well but I had several side affects which I could cope with, given that they were controlling my high blood pressure. Unfortunately I started to get palpitations I think it was gradual over a period of time until it became unbearable ie nearly passing out.

I was sent for several tests and was diagnosed with paroxysmal atrial fibrillation and a leaking heart valve and my medication was changed. I have been for two follow up appointments with cardiologist, my last one I did say I had a couple of fibrillations but not too bad. I was weaned off one of my meds (bisoprolol) then be off completely for a further two days and phone with a final Pulse rate (66.)

I have been off it since 27th September. I have not heard from my consultant since. I have been to see my GP blood pressure a little high, he was going to find out from consultant what I was to do that was on 17th October I have heard nothing so far. Should I be worried? Have had no palpitations since stopping meds.

11/2/11 I was put on Norvasc 5mg. Pharmacy filled it with the generic Amlodopine Besylate...I have no idea if that makes any difference at all, but just telling it how it was. I took the 5mg tablet at 10am Nov. 2nd, 2011. It did NOTHING to help my blood pressure!!! By around 2 pm, I started feeling so light-headed, it was like I was almost having an out of body experience.

It seemed to me like more of a psychiatric drug than a hypertension drug. I was spacy & loopy the rest of the evening/night. Called reported it to my doc. Was told the next morning to take only 1/2 (so now 2.5mg)...I took 1/2 tablet at 8:30am on Nov. 3rd. By 10am, my blood pressure increased and I again felt like I was about to have an out of body experience. I got up to get some water and was just totally overcome with a complete sense of DREAD that I just thouht I was going to freak out (I just wanted to cry, I felt like I had NO CONTROL at all...and this is NOT like me!). It wasn't depression at all...it was a complete feeling of dread...just as thought the Grim Reaper was right behind me.

I was really out of it, called doc's office, left message. A few min. later the nurse calls me back...and I have no idea what she said to me, I just told her I was going to lay down and see if I could sleep it off. Then she calls back a min. later and tells me the doc says to get the ER immediately! I got up, looked in the mirror...I was PALE as a ghost! I looked horrible. Anyway, visited the ER (husband came home from work & took me)...I was so loopy, the doc thought I was on illegal drugs, he couldn't believe Norvasc or Amlodopine Besylate could do this to a person. The doc began checking my arms for IV drug use, came across a redden area and asked about it. I said I'd had blood drawn at my doc's yesterday...that she was checking my renin enzymes as I'd been having difficulty with my BP...and she'd put me on this Norvasc...and this is why I was here at the ER, because she told me to report to the ER. Bottom line the ER doc said not to take the Norvasc or Amlodopin Besylate EVER again.

It was a crazy day! Also, on the morning of Nov. 3rd, I woke up with my lymph nodes in my neck hurting very badly, not swollen, just painful. I massaged them and they finally stopped hurting...and THIS MORNING (Nov. 4th) I again woke up with the same pain in the lymph nodes...massaged them, they felt better, but they've been hurting off and on all day. Oh, yeah, and I had a bad headache when I went to bed last night and been very tired today. Not sure how long it will take to get all this out of my system...been drinking lots of water to flush things out. I am very sensitive to so many medications...this was like a "bad trip!"

I have HTN my doctor just started me on norvasc 5mg today. After reading these comments, I am scared to death to take this drug. I need something natural. Any suggestions?

My experience with Amlodipine has been mixed. I took a 5mg dosage for several years with good control and minimal side effects until last year when my ankles, feet and legs began to swell. My Cardiologist decided I needed a stronger dosage because BP was a little high and upped it to 10mg.

After a few days of taking the new dosage my ankles, feet and legs were so swollen that blood vessels were breaking out and the neuropathy pain was unbearable. I put up with that for about 3 months and then found this site. I decided I would just go off for a few days to see what would happen with the swelling. Almost immediately the swelling went down to normal but the blood pressure climbed up over 200 after about 3 days off of it. (I had Atenelol and Hydrochlorothiazide also to control BP).

I finally went back to my family physician and told him what was happening. He prescribed Losartan along with the Atenelol and Hydrochlorothiazide that eliminated the swelling and neuropathy in my legs and feet. It took about 10 days for the Losartan to settle in and lower my BP. The Losartan also made me very sick for about 10 days with cramps, nausea, headaches, tiredness and body aches (like having flu). I am now finally over those symptoms. I almost quit that drug too but stuck it out. It's never fun to take any drugs but sometimes necessary.

After reading all the problems some people are having with Norvasc, I am wondering if you are taking the generic version of Norvasc or the original pill. I could not tolerate the generic, but do well on the regular Norvasc. It is expensive, but I get my Norvasc in Canada. I also have gotten my thyroid pills from Canada as I cannot tolerate anything but the original thyroid medication. In the USA, the Norvasc would cost me $100 a month. Instead, I pay $100 for three months. One has to send in a prescription. I used to live In Canada years ago, so the boogey man stories that are put out about Canada's health system do not fool me. Good luck to everyone and I hope you all improve.

my husband has a problem. he takes metoprolol, amlodipine, hydralazine for BP/ he is getting swollen ankles, legs and arms. he is short of breath. is there something out there to reduce this swelling? he is diabetic, kidney problems and BP.

I started taking (amlodipine) Norvasc about 2 years ago. After a year of taking the generic version of the drug, my feet and ankles began swelling. My doctor lowered my dosage from 10 mg to 5 mg. The swelling went down somewhat, but I still have occasional swelling in my feet and ankles. After two years of this, I finally asked my doctor to switch me back to my original channel blocker medication, Cardizem, which does not cause me to have side effects, unless, I take the generic brand of this medication, which affects my near and far vision.

I never thought about taking the brand name of Norvasc to see if the swelling would go away. I just felt that it was best that I go back to the drug that my body seemed to have no problems with. The reason why I switched in the first place was because of the cost of the generic Norvasc and the side effect that the generic Cardizem was causing me. When it comes to side effects -vs- the cost, I would rather suffer with the cost of paying more, as opposed to suffering from the side effects.

untreated diabetes.....?

I was put on Norvasc 5mg and Losartan 100mg and after 6 months had elevated liver enzymes. Asked doctor at that time if it could be due to the new meds as that was the only thing I did different in the past 6 months and he said "No."

Note I drink very little alcohol less that one drink a month if even that much and I do not smoke. He scheduled me to return in 6 weeks to recheck labs, leaving me on the meds. At 6 weeks liver enzymes even higher. Had to have hepatitis panel drawn as well as having ultrasound to check pancreas, gall bladder, liver and common bile duct. All returned negative.

I had looked on internet and found that post marketing experience showed some experienced cholestasis and hepatitis severe enough to require hospitalization. Informed doctor of this and he disagreed until he looked it up and then stopped both meds at recheck at 5 weeks after off meds liver enzymes are showing normal and others are going down. Doctor still does not want to believe med caused this. Unbelievable; I have not been taking any blood pressure medicine for past 6 weeks and readings have been normal including at follow up with doctor.

I have been on Amlodipine 5mg for about 2 years. I noticed an earlier comment about smelling smoke. I do not smoke yet my wife just mentioned she smelt the oder as well while being around me. Up until about 3 months ago I did not have the sense of smelling smoke. As odd as it may seem my wife went into my closet and did not smell smoke on any of my clothes?? Has anyone else had this sense of smell, and if so have you mentioned it to your MD? What if anything has come of it. I am wondering if it comes about with prolonged use through the blood stream and just now leaching out the odor....

MD

I have a question for anyone who has taken this and gotten swollen ankles and muscle aches in your legs; how long does it take for them to go away?..

Brandon, my swelling went down almost immediately. I can't tell you how nice it is to have normal size feet, legs and ankles without the pain of neuropathy. I am now taking Losartan, Atenalol, Hydrachloroizide and sometimes nitrostat. The only problem I've had since going off Amlodipine is my blood pressure is not as well controlled.

When I first started the Losartan I had some intestinal problems for a few days but that has gone away.

Hope this helps.

Also, Brandon, if you are taking any type of statin blood cholesterol lowering meds, those can cause muscle aches in your legs. I stopped taking that type of medication years ago.

You are absolutely right about physicians and samples. I have decided to try and Endocrinologist to treat my hypertension and diabetic condition!!!!!!!!

I am a 29 year old female on Norvasc for migraines and have noticed a decrease in my sex drive. Is this possible??

People's Pharmacy response: Yes, sexual dysfunction in women has been reported as a reaction to Norvasc.

I have been taking 10 mg of amlodipine for high blood pressure but my pressure is still in the 148/77 range. Days that I run my pressure is 120/75. I want to switch to a former drug atenolol (12.5mg) which was consistently controlling my pressure without the huge spikes on certain days. I have 2 scotches every night as well. Is there any harm in my suddenly making the switch back to atenolol?

People's Pharmacy response: Please check in with your physician. S/He may have had a reason we don't know of to change your prescription.

My husband was very into romance in our marriage, you know the kind that couldn't pass you in the kitchen without touching you. He went on Amlodipine, and its like I'm living w a stranger. He diffinitly see's a difference. Anyone out there, with a suggestion for this problem?

Regarding low libido question posted by "Melissa". I have experienced this problem but I am on two other BP meds besides Amlodipine (5 mg). I also take Aliskeren (300 mg) and Edarbi (80 mg).

I am heavy (BMI=38) and my BP is not that well controlled. Also I take a variety of other meds for various other conditions some of which may also effect libido of which I have essentially none.

I started to take in addition to my other bp meds and I'm not sure if I have a side affect or not. I'm experiencing extreme hand arm and leg pain going into my back and neck. It feels like my whole leg and arms including feet and hands are just aching muscle and bones. It is worse at night and I have now started to take pain tablets to help me. Now even during the day the symptoms are not lessening and I'm not sure what to do.


does anyone have the same experience?

I took norvasc last year and I too had these weird out of body feelings. It felt like I was outside myself and watching myself. I stopped taking it and went on a diet to drop my BP instead.

Swollen ankles are a documented side effect of norvasc. So it would seem that anyone taking it is at risk for getting an expensive medical work up for heart failure because ankle swelling is a symptom of that disease. Instead of switching the
Norvasc-prescribed public to a diuretic like chlorthalidone like this website suggests Mds will order a barrage of expensive tests because they will use fear-mongering to convince you it is a zebra when it is simply a horse.

Goggle for side effects & take your information to your doctor.
Nan

So happy to have found this site! I was prescribed Norvasc {generic} for slightly elevated B/P/ I've not been on any meds until now and will not continue taking this one either! I work in the operating room, standing on my feet all day, and this past week {after taking this for 3 weeks} my legs and feet started to swell and the pain was so horrible I wanted to cry! I had this reddish looking rash on my lower legs and the skin was so tight I wanted to scream!
What the h*** is wrong with docs anymore, prescribing these meds?

I haven't taken it today, rash is gone, swelling is gone but legs still feel tired and achy.

I'm going with a total diet change, exercise ...ANYTHING to lower my pressure. {and 152/92 isn't stroke level, coming from the surgeons, I work with} And I work at a TOP Hosp in the Country. I'll trust them over the Internal Med who prescribed this muck!

Oh..and I've called the MD Office 3 times this week and NO return calls! I'll be finding a MD who isn't too busy pushing a patient out the door every 20 minutes to make a quota!

I am taking 10mg of Norvasc daily, for about 1 1/2 yrs,(used to take 5 mgs)
I just suddenly am falling down for no apparent reason, today also a couple months ago, and last May I fell and broke my right humorous. I had NEVER PREVIOUSLY had this problem before my high bp meds.(I'm also on Rasilez). Also I do get swollen ankles, especially after being at work at my desk all day.

People's Pharmacy response: Be sure to discuss this with your physician. Swollen ankles are a known side effect of Norvasc, and there are other drugs to help lower blood pressure. If your falls were triggered by dizziness, that too could be a side effect.

I have been taking 5mg of Amlodopine forv a few months, having been taken off Losartin because of a reduced kidney function which was caused by anti-inflamataries taken for bad osteo arthritis. Feet and ankles swelled up, kept cutting out amlodipine for a week or so at a time to reduce swelling. A few weeks ago my left leg got swollen so badly, especially round ankle and calf. Went to GP who sent me to Hospital for DVT test which proved positive. I have to inject Clexane into my stomach daily until my blood thins to between 2 and 3 and am taking 5mg of Warfarin daily.

Could this have been caused by the Amlidipine? I am 74,have never smoked or drank, don't go on planes, eat well, exercise at least 3 times a week in water, go for short daily walks.

People's Pharmacy response: Thanks for calling out one symptom that requires a doctor visit: one leg is very swollen, more than the other one. That could signal a blood clot like the one you have. We don't know if amlodipine increases the risk of DVT.

I started on Lisinpril for high blood pressure in late 2009, early 2010 but do to side effect of "dry cough" my doctor switched me to Amlodipine. I was on the lowest dosage then because my blood pressure was still high, my doctor in increased the dosage.

In the summer of 2010 I noticed a "bald spot" the size of a quarter on the back of my scalp. Within several months, all my hair had started to fall out! I also have lost my eye lashes, eye brows and most of the hair on my body! I now have to wear a wig constantly when not at home! I am only 50 years old and I was horrified that someone who always had "a lot of hair" by my hairdresser could be losing there hair at such an alarming rate!

Has anyone else had this happen after going on blood pressure meds? I have been on thyroid meds since age 25 and have had bouts of partial hair loss off eyebrows, but nothing of what I am experiencing now! It's horrific! Another doctor I went to did numerous tests and his only conclusion was I was vitamin D "deficient". Then here recommended I see a "plastic surgeon" for the hair loss! I have now determined this doctor is an "insensitive" JERK! It is bad enough I have started MENOPAUSE but to lost ALL my hair too? TOO MUCH STRESS!

I have discussed my severe dizziness with my physician, but he has not chosen to change my medication! The dizziness and fatigue is worse at times, but I now fear I may lose my balance and fall! Can anyone recommend a way to lessen this side affect or mention another blood pressure medication in place of the amlodipine I am now taking?

I would find another doctor. Preferably a geriatric doctor.
You should not have to put up with that.
Good luck

I started this med 2.5 mg. Almopidine Besolate for HBP. It gave me seizures, extremely high BP spikes, dizziness, & a weird smell of tar/turpentine. Swollen ankle feels like my right ankle is broken. I have been off of this drug for 2 weeks & my ankles are still paining & swollen. Called my Cardio Dr. told him I was off of it.... he had no comment. I called my primary same thing told her this med was causing seizures.

Took this drug for 9 months never realizing it was the real cause of my problem... Now I know, never had any allergies or reactions to any drugs/food in my lifetime till now. Not a good drug for me......AG

I was taking DIOVAN 340 with HTC 12.5, Atenolol 100mg and Nifedipine 30 time released. My HBP always remained high and my ankles swollen. The doctor stopped the Nifedipine and I continued with the remaining medications, but my HBP still remain high. 3 months ago he added Almodipine 5mg. At last my HBP went down to normal; 117 / 11.4 which is wonderful... but the well known side effects of Amlodipine, SWELLING ANKLES disturbed me a great deal.

My friend suggested that I drink Cranberry juice for the swelling of my ankles. I am going to try it but I am afraid that if the doctor decided to stop the Amlodipine (IMPORTANT MAKE SURE TO WEAN OFF MEDICATION BEFORE COMPLETELY STOPPING ) my BP will rise again. WHAT NEXT TO DO?

Hi, I was prescribed generic norvasc Monday... by Wednesday I felt like my chest was going to erupt! I called my doc n told him I couldn't take this med, it was doing nothing for my BP and it was killing me... he wanted me to go to cardiologist... I explained it was an allergic reaction... he argued, so I went to another doc... took me off of it put me on lisinopril (which I have been on in past with no ill effects) and BP is under control today... Thursday, but the tightness is still in my chest. Had an EKG heart is fine ... how long is this stuff gonna have me all bound up?

why does amlodipine and losartan make my blood pressure rise?

Sabrina, I would like to know what are you taking now for your blood pressure. I also am very sensitive to drugs and am terrified of taking BP medicines, but I know I have to take it. Today is my first day I am taking Hydrochlorothiazide 12.5 mg. The doctor also prescribed Amlodipine 2.5mg, but after seeing all of these negative comments on this site, I am afraid to take it. Thanks

Yasmin, I currently take 50mg. Tenormin, the brand name for the generic Atenolol. It costs more, but it works much better than Atenolol did for me. I've also been exercising more, doing yoga and water Tai Chi (called Ai Chi) at my health club... but even better than that, I've been getting acupuncture done once or twice a week.

Acupuncture has been great! It's really helped to unblock energetic blockages and has helped me to "flow" with life. Along with all this, I do meditation once a day for about an hour. I have found some great meditation cds that really help me to totally relax. I'm really beginning to understand how our feelings/emotions impact our health. I've learned, or am learning, to release negative emotions/energy, resistance and judgment to God, or the universe, if you will. I also drink lots of water (non-chlorinated water, not city water), and herbal teas.

My blood pressure still fluctuates at times, but, I've noticed after meditation it's been awesome! Just a few days ago, I took it after meditating and it was 97/59! I'm not endorsing any of these things mentioned... to each his own, but these are the things I've been doing and they've helped me greatly.

I'm really trying to take responsibility for my health and my decisions are based on the fact that we are not just physical beings. It's the mind/body/spirit approach that I honor. I also read lots of spiritual books. The cds, if anyone is interested, are by Dr. Jeffrey Thompson. Thank you and many blessings!

I have been taking norvasc for years now also but just within the last 3 months the doc doubled my dosage, I had noticed a cigarette smell before but just briefly but now that he has doubled it I have blurred vision and am noticing cigarette smoke a lot more and I too live in a smoke free home? I unfortunately signed on to webmd (don't go there unless your not neurotic like I am) I typed in my symptoms and it said I had everything from diabetes to mini strokes!! I freaked and went to the doc, he gave me some nasal spray thinking it could be congestion or allergies and did an eye test for the blurred vision, if symptoms persist he is scheduling an mri next week but now that I read all these people smelling the same thing from this drug I don't know, nice to know that others are smelling the same things I am:)

I am a 73 year old man. I was given Amlodipine for swollen ankles and started feeling lightheaded and passing out. The Dr. took me off it and I felt fine then he said I had a irregular heart beat and prescribed Warfarin and Metoprolol. I started feeling lightheaded and passing out. I seen the heart specialist and he stopped the Metoprolol but not the Warfarin. The Warfarin makes my feet breakout with a rash and itches like crazy. I wore a heart monitor for a month and the specialist said that when I felt lightheaded that my heart was slowing and when I felt like passing out my heart would stop for about five seconds.I am now off the Warfarin, Metoprolol and Amlodipine. I think that the Amlodipine was the fault in the beginning.

Thanks Sabrina, your experience is a light in a dark page of horrible experiences. I just started HP controlling medicine today, (Amlodipine 5mg) but hope that I will not have to undergo such extreme side effects. Over the years I have practiced yoga and meditation and I have been a vegetarian for many years, still, due to reasons I cannot say, I developed very high BP, so your experience has reinvigorated my determination to try and keep the BP within bounds by natural means while at the same time monitoring the side effects of this medication. God bless you and may you live a long and happy life.

Thank you, Mahashakti, for your very sweet post. I am touched. I honestly love getting acupuncture treatments done and it really helps to settle me... and my blood pressure. That, and exercising with the help of a personal trainer at my local health club helps a lot. I do wish you the very best and may God bless you and you live a long, happy & healthy life, Mahashakti!

Has anyone developed a hard cough after taking Edarbi 40/12.5. I am coughing so bad I have a sore throat. Was on Diovan 320/12.5 for years but Dr. put me on Edarbi and after a month, I starting coughing. It has controlled my blood pressure better but I don't think I can deal with this. I know Edarbi is a fairly new drug so wondering what others may think.

I am 76 year old female, used to long walks and being on-the-go, and am in excellent health except for elevated BP. I have slight osteoarthritis and Reynauds syndrome. For the past 7 months the only medication I have regularly taken is 10mg generic amlodipine bestylate. I started taking it in the morning but then switched to bedtime to see if the side-effects would lessen. Not a lot. I have had severe allergic-type reactions to most of the Alpha and Beta blockers.

Just prior to amlodipine I was taking 90mg nifidepine without many side effects, but it was not controlling my pressure enough (150-160/73). While taking amlodipine, I have experienced considerable loss of the sense of smell and taste. I have sudden bouts of faintness, loss of balance, insomnia, hot flashes, extra heart beats, and daily muscle cramps. I wake more frequently to urinate. I always feel drained, and don't have the desire or energy to do anything.

I do NOT smell cigarette smoke - I hardly smell or taste anything! I do NOT live alone, I have many friends and a loving family.

I had taken 5mg amlodipine for years along with 37.5 mg diazide for fluid retention. Recently, my amlodipine was increased to 10 mg and now I am experiencing severe swelling in my lower legs feet and ankles. My description of my feet are that they look like turtles with five heads. I am wondering if the 10 mg is causing the problem. haven't discussed it with my doctor yet.

I took lisinopril for about 6 years and suffered massive hair loss. I had always had a thick head of hair with no family history of baldness. It was strange in that it was like your situation. I started losing my eyebrows and the hair at the temples. I stopped the lisinopril when I suffered kidney failure. Now my doctor wants me to start Amlodipine 5 mg to help my BP. I do have a problem taking some drugs and I hope I will not be back here telling you a bad experience. I think I will start slowly with a half a pill to see what my body says.

I was prescribed 5mg of amlodipine besylate about 3 years ago for slightly elevated blood pressure.The only negative that I noticed was that if I missed a day or two I would have bad headaches and some chest pain. Mentioned this to my doctor and he seemed to dismiss it (no real response). June of 2011 had a routine physical and was told that I was in great health, however, when my bloodwork came back two days later I was informed that I had diabetes. No family history of diabetes at all, I'm 6'1" and weighed 225 at that time and relatively active. Diabetes was a shocker.

At about the same time I had noticed a tingling sensation in my feet. Doctor again dismissed it when I would ask him about the numbness. I lost 35 lbs. and seem to have my diabetes under control with no medications, but the numbness (peripheral neuropathy) has persisted and seems to be a little worse. Even after two visits to a neurologist, I still have no answers. After a restless night of tingling feet I decided to check out the side effects of my bp meds and have been surprised at the many comments regarding this drug. Is there any actual evidence that amlodipine can cause neuropathy and what is its relationship with diabetes?

Just got out of the hospital after being in around three days. Had to be rushed to ER by ambulance after almost dying from reaction to generic Norvasc. Starting having severe chest pain, started taking glycerin for that and my blood pressure dropped so low, I was losing consciousness. Had all kinds of heart tests done while there, the specialist took me off generic norvasc because I had all the symptoms, chest pain, throat pain, leg swelling and pain, nausea. I had been on Norvasc for years and the veterans administration switched it to the generic. That was one scary experience, don't know why the doctors do guinea pig testing on people.

Have just looked down site as I've been on Amalodopine 5 mg for three months. My BP is very erratic and has hit very high spots (220/112) Doctor now has added beta blocker bisoprolol 2.5mg. Am concerned about combinations. My heart rate can be in the high fifties (at rest). Also concerned that doctor has done no ECG or even listened to my heart through stethoscope. Thinking of quitting the amalodopine and not starting the beta blocker. BIG thanks to Sabrina for her positive comments. I am enrolled to do mindfulness meditation over the first weekend of June and also want to work with visualizations and acupuncture. Any comments (positive ones!) from anyone on combined beta blocker and calcium channel blocker would nonetheless be welcome. Warm wishes to you all.

Thank you, Morag. I do hope you find what does work for you. I just had an acupuncture session earlier today and it was great! I've been very stressed out for the past few weeks and hadn't been getting acupuncture done (just been too busy) and it was such a great, relaxing session. I hope you find a great acupuncturist and can get the results you need! Also, exercise is vitally important to keeping the BP down. If you do nothing else, walk, walk, walk! Oh, yeah, and eating fish and/or taking Omega 3 is great for your arteries...helps to keep the elasticity in them. : ) Take care and best wishes!

Norvasc cigarette smoke smell illusion.
I too noticed a higher sense of smell and false smell of smoke.
I too live in a smoke free home.

Dosage: 1 octagon a day, generic.

Side note. I don't smell the smoke anymore... just two or three times.
I believe that stressers, in association with norvasc, are responsible for the smoke effect. I also notice a dry, stale water smell too. PS. I am on no other drugs. Because these smells are common in our environments, I believe they are often rationalized away in our minds. Thanks again to the internet for bringing these things to the light.
Grant
The 10 cent physiologist

Whats you're 2 scents? ;-)

my age 38 and sometime my blood pressure 160/100 or 150/90 also heart beat is fast

any body advise me please thanks you

I just started taking Amlodipine 10mg substitution for (norvasc) 10mg....greenstone ...this is my first day and I'm very scared with all the side effects I see on this website... my question is can you help me with this diet you were talking about I would rather go that route....please help

I would like to add that, after tapering off my beta blocker (no, the good "dr" didn't tell me to, I had to figure it out , when my bp skyrocketed to 180/120 and he told me to "yeah, go ahead an take a half twice a day for awhile with the half a calcium channel blockers and see what happens"!!) to a calcium channel blocker... my gums started swelling and when I would eat something cold, my cheeks would get so numb that I kept accidentally "biting" them? and, weirdest of all, we had recently changed our kitchen faucet, so, I naturally associated the odd taste in my water with the faucet!

We mailed it back to Moen, who replaced it, and finally drank the water through the pipes --the taste was still there! My boyfriend never tasted it... then, I had a glass of wine, a familiar brand, and it tasted metallic... then, I looked on the internet.. I cannot take diuretics (I have gout, and cannot) and I developed anaphylactic shock to lisinopril... beta blockers make me so depressed, I am beginning to wish I had never been Dx with hbp and had just kicked off...

Mellissa you are saying your husband was very attracted to you. You noticed a difference in his moods after he started taking amlodipine? Lately my husband seems like he is in a fog. Has very little to say. He is extremely moody and exhausted all the time. Did not think it was a side effect from the meds until I started doing research. Thanks for your comment.

When I was placed on norvasc I started feeling really tired and even after ten hours of sleep I could barely drag myself out of bed. I called the doctor and he said give my body time to become accustomed to the new medicine. Then the depression set in so 6 months later I had another appointment and mentioned the depression and that I always feel tired and could sleep all day. His response was since I was retired I could afford to take catnaps when I felt like it. He also said that he never heard anyone mentioning depression as a side effect and asked if I wanted a prescription for an anti-depressant which I declined.

I think doctors don't really know anything about health issues except prescribing drugs to mask the symptoms. Doctors are good for mending broken bones and that's it. Their protocol is to mask the symptoms but never cure the patient. Its like putting black tape over your "check engine" light so you don't see it and think the problem has been solved.

I have seen references to peripheral neuropathy as a side effect but I have been advised to lower my blood sugar and seek carpel tunnel surgery. My blood sugar is lower and the nerve conduction study shows the carpet tunnel is only moderately limited.

I continue to have severe pain in my right hand, numbness in all four extremities that seriously affects my sleep. Have tried magnesium creams, vinegar dips, B-1, B-12, Voltarin, Advil, wrist braces ... only voltarin and the braces were even helpful.

I need some sleep. Any ideas? What kind of doctor would you go to?

I was prescribed AMLODIPINE for several years to lower my blood pressure. As soon as I started I reported having a loss of sexual drive. Because of my age I actually welcomed this. But as each month moved by I began to experience tingling in my hands and a progressive feeling of my feet becoming kind of dead. I complained to my primary care physician but he only suggested that I take Naproxen Sodium (Aleve). At that time I didn't know that I shouldn't take this because I had a hiatus hernia and GERD. I wound up in the hospital with intestinal bleeding and received three units of blood.

When my doctor changed my pain reliever to Acetaminophen I complained that it was inadequate and reviewed my worsening symptoms. He replied "it's only a little neuropathy. The last time I saw him I complained that the AMLODIPINE was not properly controlling my blood pressure. He wouldn't even look at the blood pressure test records I made at home. I had one of my sudden sharp pains in my left thumb right in front of him. I complained more of the pain, odd feelings in hands and feet, and my inability to walk straight. He replied "Nobody should live past 75."

Since it was now clear that he was not interested in my health care, I fired him. Three months later I found another physician to assist as my primary doctor. At my initial examination he referred me to a neurologist. The neurologist used a shock machine to measure my neural responses. He then announced that I had moderate poly neuropathy.

My new primary doctor later said that my neuropathy was caused by AMLODIPINE. He then prescribed a different class of blood pressure medication. The result during the last three months, I feel like my life has been saved. Most of the pain and feeling of deadness is gone. I still have a little difficulty walking straight on irregular surfaces, but I am very encouraged by this great overall improvement.

I filed a complaint with the State Medical Board against my prior doctor. Their response is that it takes three months to think about investigating, three to six months to investigate, and another three months to decide to proceed if I am or am not represented by legal counsel.

A quarter million Americans die each year because of doctor caused illness. Approximately 90% of these deaths are caused by prescribing inappropriate medications. I believe it will continue this way as long as doctors are protected by their peers and not held responsible.

HELP NEEDED!
My mother is 78 years old and is presently on Medicaid. When she worked for the state, she had medical insurance but due to her current income, she had to go on Medicaid. Before she retired, she was diagnosed with Thyroid problems and that doctor prescribed Synthroid to treat her condition. This large clinic left NC and she was forced to go to a different doctor. She has been seeing this doctor that works for a large clinic out of Rocky Mount , NC. When she first went to them she was only on Synthroid and she has always been very healthy up to that point.

I am very concerned about the knowledge of the doctor that she has been going to since. There has been many questionable things that this doctor has prescribed in the past, the latest is Amlodipine and generic as this is only what Medicaid will pay for. I used to go to the same doctor and clinic and the last straw I had with him is when again he paid no attention to the problems that I said I was having. One time he even threw some sample Zoloft to me when I commented on his excess weight!

Over the years, he has prescribed her numerous medications which are questionable to me. He only spends no more than 15 minutes with her and sometimes only checks her blood pressure once and the nurse checks it before him. At the time we purchased a blood pressure monitor and it did not show that she had high blood pressure and when we pointed this out to the doctor, they then must have done something with their monitor as it began showing the same pressure as we were having, however before it showed her blood pressure much higher on theirs.

I kept checking our blood pressure monitor when he started increasing the medications several times a day for weeks we checked it and her blood pressure was always lower than mine and I do not have any medication. He started prescribing blood pressure medicine and as well as others years ago and since has added and added even more. When we go to the pharmacy to pick up her monthly supply of prescriptions now, we almost need a shopping bag. I

The latest drug he prescribed was Amlodipine. Mom has been complaining recently, especially so when he upped her prescription strength, about her legs and ankles swelling and making it difficult to walk. Also she is extremely tired most of the time. I looked up Amlodipine yesterday and found many disturbing things about it. She seems to have most of the side effects listed and then I saw this website and read all the entries. I really believe that the doctor barely made it through medical school and has put her in her age group class and prescribed her all the common prescriptions for that age group. He even had put in her medical record that she had a history of congestive heart failure and when she confronted him about this he gave no explanation or even knew how it got there. I would bet that if I could see all the other women's health records that he sees in her age group, that they are being prescribed the identical or similar medications. We are not cattle.

When she complains of a problem, he always brushes it off. I made her call him up as normally advised to report her condition and they said they would call right back. No call and still waiting. She said she was not going to take any more of it but after I researched, I told her not to stop abruptly and am considering having her try to wean herself off of it while we start to take her blood pressure frequently to monitor it.

I am not sure of Medicaid's rules but I think she needs to go to a specialist to just see what this doctor has been doing to her so we can see what the course of action we need to do. If there is anyone out there who has some advice as to what we should do, it will greatly be appreciated as her doctor is absolutely no help and I believe he has caused most of her problems.

Thank you in advance for any help!

Finally after reading so many of these comments I've found someone experiencing the same problem I'm having and I'm only 6 years older than you. I too take Amlodipine 5 mg (for about 6 months) and I noticed that my hair (and I had lots of it) was feeling very "thin" after each washing. I started having a hairdresser wash it because I just don't have the energy to do it myself anymore and she's noticed that my hair is coming out from the root and not breakage (her words) and she asked if I were taking any meds and if so I should ask my doctor if it's possible this is making my hair fall out. As soon as I finish typing this I'm going to e-mail my doctor so thank you for posting your experience with this drug.

I have had all side effect with amlodipine. I am now taking the pill at bed time It works feeling much better in the am . B.p. and heart rate both lower.

Hi, I would like to help so here is my experience with Amlodipine. I was taking this drug 5mg for years along with Atenalol for Hi BP and Angina. That worked pretty well for awhile. Then my chest pain got worse so I had a stress test and my regular physician wanted me to see my cardiologist. The cardiologist only wanted to up the dosage of Amlodipine to 10 mg to lower my BP. I took that for about 1 year and had the same symptoms your mother had. Swelling in legs and feet, neuropathy (pain and numbness) in my feet and legs until I couldn't take it anymore.

I finally called my doctor and he put me on Losartan 50 mg and Hydrocholorothiazide 25mg and took me off the Amlodipine altogether. I went for another 6 months with that drug but my Blood pressure was crazy elevated up and down so I called my physician back and told him my BP was going up into the 200's so he asked me to restart the lower dosage of Amlodipine .5mg along with all the rest of my meds.

Finally, I am leveling off on the BP's around 135 over 80's which is very good for me and am having no more swelling in my legs and feet. I do have a little tingling and slight numbness occasionally but nothing I can't handle. So, here's my meds as I am taking them now. Losartan 50mg, Atenolol 100mg, Levothyroxine 150 mg. Amlodipine .05mg, Hydrochlorothiazide .25mg. And If I have a spike in BP over 200 I have a pill to take called Clonodine hydrochloride 0.1 mg.

It took awhile and some experimenting but I finally have the bp under control and no problems with swelling. I am Medicare and all these drugs have been covered. I believe they are generics. Actually, they are 4.00 rx's at Walmart and Walgreens so very cheap. Hope this helps.

Bill,
Can you tell us what HBP medication you are taking now? So glad you found a doctor who is listening to you. It is so difficult to find a good doctor nowadays. If you are of a certain age, it is especially hard since we know what a good doctor is. It is difficult to have patience when we see what doctors have become. "Do No Harm"....ya, right.
Good luck,
JudyL

Barbara, yes my Mom who is currently taking this drug is experiencing this! In fact, after falling in her bathroom she now is walking with a cane. I'm so mad @ idiotic Drs. that don't know about a drug's side effects! She saw one last week that told her "no that drug is not known for that type of side effect". Well DUH, I got news for him that YES it is.

I understand the frustration you have with the Doctor providing lousy medical care for your Mother with drugs that are probably not actually needed and therefore endangering her health. In the Federal Building of the capital city of N.C. there should be an office for Medicaid and Medicare. This is where you need to file a major complaint against this Doctor who WILL BE investigated because he is billing the Federal Government for the care he provides for your Mother.

This office has concerns about the competency of physicians who treat patients and send their bills to Medicaid. There are a great number of physicians who should never be allowed to practice medicine, no matter who pays the bill. There is a tremendous amount of medical fraud that goes on with inadequate physicians. It is time to cull out these louses and clean up our medical profession. Doctors bury their mistakes, for sure but the bad ones bury more than the good ones. They could also give you information concerning obtaining a competent physician who can hopefully undue the damage done to your Mother. I wish you good luck, do not give up. Help is out there, you just need to find it.

I took Norvasc for several years. When I was on it I did notice that it affected my sense of smell. One thing was that I could not stand the odor of yeast bread. It was always a smell I had enjoyed before. Another thing was that I also could not stand the smell of my own urine.

Norvacs also caused me to have a lot of broken capillaries in my legs which would bleed under my skin. Now I have areas of darkness around my ankles caused by the bleeding.

I also did not have the capacity to watch TV or anything at night. After making dinner and washing the dishes, I had to go to bed.

I did not realize it was the Norvasc that caused all of this until I finally got off of it. All of the symptoms that I have described went away after stopping Norvasc.
I now take a calcium channel blocker called Sular. I do not have any of the side effects I had with Norvasc except for some swelling around my ankles each day.
I wish I had never taken Norvasc. I would like to stop the calcium channel blocker I now take, but I fear that my blood pressure will go up. I also take Avapro and Lasix for my BP.

I have been taking norvasc for 16 years, it has not killed me. The druggist gave me a generic and that was totally sickening.

After 16 years my sex tools have fallen short, other than that norvasc works and doesn't work at times. My blood pressure is what ever it wants to be, from 124/78 to 156/91. I am a black American, I do not smoke, drink or eat meat at 70. Is 120/80 to much to ask for?

Why don't professionals listen to the people actually taking the drug instead of the manufacturers? EVERYONE who has written in on these sites -- even those who liked amlodipine -- has had trouble with swollen legs. Yet you say it's 25% at most. I had problems with dry eyes and blurry vision while on Benicar. My doctor said, "Oh no, High Blood Pressure causes that." -- now it's listed by the company as a side effect.

Yes. The FDA website has it listed.

After reading all the comments about this drug I just had to add my two cents. I'm 71 and have had migraines at least once a month for 40 years. I also got a low level headache that usually led to full blown migraine if left untreated, about two or three times a month. I avoided all alcohol, bright lights and long hot drives most of these 40 years, because they along with chocolate were definitely triggers.

In October of 2011, my Dr put me on 5mg of amlodipene besylate tabs. (Norvasc) He said I was on the edge of being hypertensive and this would lower my BP, which it did.

Since Oct of 2011 I have not had one headache. NOT ONE. I can now drink wine and beer and scotch. I can eat chocolate and be in the sun all day. I have had no side effects from the drug and its has opened up a whole new life for me.
My Dr said it used to be a dual purpose drug, but he is also amazed at this turn of events. It may not be for everyone but it sure has given me a whole new life.

I am on istin (Norvasc) for 2 years, beginning with 5mg daily in the morning. I noticed it worked well to bring down my bp, but I began to have a dry ticklish cough, it started about the same time every evening. It was very annoying. I mentioned this to my doctor, who dismissed it and said the medication does not cause this, and I must have a chest irritation or cold. I knew this not to be the case, I have never had coughs or chest trouble.

I halved the dose to 2.5mg and the cough stopped. Blood pressure seemed to stay ok although I confess I rarely checked. When at the doctor it would be raised, but I felt that at home it was ok.

Anyway, in the last few months I have had a new complaint which I suspect is caused by the Norvasc. I take my dose in the morning, I usually go for a walk in the afternoons with my dog. I noticed that I get a severe chest and back pain if I walk in the evenings, but earlier in the day I am fine. I know it is a slow acting drug, so is kicking in fully at this time I think. I am also a bit afraid to stop it. I know what my doctors reaction will be, she will deny it is the medication.

The other strange thing that happened to me since starting the drug is that I had a spontaneous fracture in a pelvic bone, although I have had a dexascan and my bone density is good.

I have two elderly aunts (I am 56), who have taken Norvasc for over 20+ years with no problems, and so I felt it was a safe drug for me. But it is proving to be unsuitable for me, I feel sure it is causing the chest and back pain (angina type muscle pain) when I walk in the evenings.

Has anyone else any experience of the same thing?

Amlodipine Besylate 5mg. 1x daily. Generic Mfg. Lupin Pharmace:

My side effects from this BP medication have many similarities to a lot of folks posting here.
Peculiar odors,"out of body" (very similar to a panic attack) experiences,"Dead leg" feeling on the left side (not muscle, but skin, as if the skin went to sleep, I can can stick a push-pin in my leg without feeling it, just pressure) ,Depression, major respiratory allergic reaction (major sore throat, sneezing, coughing, wheezing, as what seems to be similar to bad hay fever), which I never had before. Severe weakness, pain & swelling in feet, ankles, hands. Blurred vision, loss of taste & smell, muscle pain in feet up to the lower lumbar.

Stopped this med once before,about 9 mos. ago due to side effects which were 50% of the current, i.e, different manufacture. I believe that Generics "DO" vary in composition, and "fillers". I am tapering off & stopping this med. I would rather die of natural causes than doctor or Mfg. induced.

My Doc? - a Community Health Clinic MD. who only has 10mins per patient.They throw pills at you like rice at a wedding.
Learn to take care of yourself, no one else has the time...
Good luck to all.

Hello Ken,
One of the reasons my doctor put me on Norvasc, besides for HBP, is to get rid of my migraines. I will still have one on occasion if I am around someone with perfume on, or if I am around air freshener. Otherwise, like you, I have been relatively migraine free for years now. Such a relief. My doctor could not help but be happy for me and said "See, I told you I would take care of them." I take my Norvasc (10mg) at bedtime, and I take the original form. I only lasted a couple of days on the generic. So glad you were helped with your migraines, too. Enjoy!

JudyL

Just stopped Amlodipine after only six weeks for High BP. Sometimes 156/90.But swollen feet and calves and knees with pain made me think it must be the Amlopidine and Dr. said to stop taking it and swelling is going down. Also on 20 Lipitor for years with no problem suddenly changed to Atorvastatin which they try and tell you is the same as Lipitor. I have insisted I go back on Lipitor as I believe replacements are always different!

Hi, ER. are you still taking the Diovan? How many mg? I am speaking with my cardiologist early in Aug, 2012 and want to review my meds with him as what I am taking is not consistently effective.

I have the generic of Cozaar (losartan) but have read studies that state that (valsartan) Diovan is far superior in terms of getting the job done. I am maxed on the losartan at 100mg daily, I also take Amlodipine 2.5 mg, Atenolol 25 mg, Hydraclorthiazide 25 mg., Clonidine 0.1 mf twice per day and .03 at bedtime. Included in my regimen is Ativan .5 mg three times per day. My blood pressure is still a yoyo. I did get a reading at the MD a few months ago of 121/76 so he thinks I'm fine. My readings at work (I am an RN) run as high as 212/118 which I find frightening. I consider myself fortunate if my reading are no more than 150/85.

I check my pressures at home and they are equally distressing. I don't seem to be able to convince my MD's that I am a high anxiety person by nature and need something more that .5 mg Ativan 3 times per day. The GP did eventually prescribe Zoloft 75 mg but it gave me the jitters so badly that I thought it was making me even more anxious so I weaned down from that to zero within 6 weeks.

I used to be on Norvasc along with other medications about 10 years ago. I was experiencing dry mouth especially at night when I am going to bed. I was not able to sleep at all tossing and turning all night even after having sips of water each time that I could not swallow my saliva. I reported it to my Consultant, he replaced the norvasc by something else and the side effect was gone.

After some 10 years later, for some reason a new Consultant reviewed my medications and put me back on it. I forgot completely about this side effect or perhaps I thought this time my body would have no problem with Norvasc. Soon after I took the first dose, the side effect came back. I can't sleep at all at night due to the dry mouth even I take sips of water several times each night. So this morning I called the Consultant to explain my problem, then I mentioned the past experience with Norvasc. He suggested that I cease it as from today and I will be reviewed next week.

I recently started using doxazosin for high B/P. I am a Paramedic. I have seen every side effect possible over 20 years. Never in my life imagined this side effect but a day after taking I constantly smell cigarette smoke wen absolutely I am not in a smoke environment? I'm even embarrassed to mention to my doctor such a crazy thing. And for sure without a shadow of doubt I am smelling smoke that is NOT there.

I have the same problem. I used Norvasc for years and went to Amlodipine and am now having side effects. There has to be something in Amlodipine that is not in Norvasc.

I used amlodipine for years without any problem. but lately my feet and ankle got swollen, especially if I drink soda or any carbonated drinks. and Dr said I am pre-diabetic. I have no family history of diabetes so switched to hydrochlorotiazade and that one just killed my thyroid, switched to losartan that one elevating my blood sugar. I don't know what to do!

I take amlodipine 10mg. This is embarrassing, but since taking it, I have had an external vaginal itch that is unbearable. My gyno found NOTHING wrong, and the creams she prescribed give minimal temporary relief. A doctor friend suggested it could be the medication after ruling out gyn problems, food allergy, detergent allergy, etc.

I did read that the "fillers" sometimes cause allergic reactions, but it seems I am the only one with this problem. The medication has really helped regulate my BP so I don't want to stop taking it unless I am sure this is the culprit. Has anyone experienced anything like this??

GA Plz check your blood sugar right away it may be diabetes.

Hi everybody omg for the first time I end it up in the ER and my bp was 200/119 and the Dr. told me I had high blood pressure, I told him I never had high blood pressure and he giving me amlodipine besylate 10 mg and I always exercise and work out all the time but now I can even walk 2 blocks and I feel my chest tight and tired.

I'm getting a lot of cramps in my right shoulder and hands which I never felt before, but ever since am taking this medication and lisnopril 20 mg I'm feeling a lot of crazy stuff, I feel light I got weight in my neck and shoulder and a lot of headache and dizziness and in balance that I never felt before, my legs I'm getting cramps and swollen too. wow and I'm reading all ur wrote and now I'm scared too.

I'm going to talk to my doctor this month when I go . ty u all for ur comment , I just hit 51 and I never had all theses problems before. God bless u all and I will pray for u all and myself that god keep us in his wings and safe, ty

I'm 39 and was diagnosed with mild hypertension over two years ago 148/95. I can't remember the name of the drug i was initially on but I remember stopping it because it wasn't helping.

About 9 months ago my Dr. started me on Amlodipine Besylate 5mg and immediately I noticed my blood pressure came under control and never got any higher than 133/84. I just recently took a trip to Oregon from Hawaii where I reside and developed over a 5 day period what appeared to be chicken pox but instead turned out to be an allergic reaction to the Amlodipine. It may sound crazy but I honestly feel like because my immune system had to deal with a new environment and different foods, it no longer protected me from this side affect.

The rash or hives as I call it are all over my body and only mildly itch. My doc prescribed Prednisone 10mg for the rash and I’ve been off the Amlodipine for 48 hours now. Sys. Blood pressure is instantly back up to 133 (seems like a magic number for me) and for the first time, I have mild pain and weakness in my ankles and calf muscles.

I got on this blog to find out if there were any adverse side affects to stopping Amlodipine cold turkey (can anyone answer this for me?). Instead I found a wealth of information on this drug. I am very curious however if the true cause of this reaction only occurs in the generic version of this drug. Specifically by the manufacture "Greenstone LTD."

I need to get back on something to control my hypertension but I'm afraid of drugs now after reading this...

Is your generic prescription manufactured by Greenstone LTD.? If so, it may in fact be the culprit. But that’s just my personal opinion as I recently broke out into hives taking the same dose as you by this manufacturer. I too want to stay on this drug as it seems the only thing that works for me but I may have to resort to the brand name Norvasc which can be quite expensive unless purchased thru Canada. Good luck and I hope this helps.

John P.
I have been getting my Norvasc from Canada for several years now. It cost me $100 for a 3 month supply and I have not experienced any problems receiving my medications in a timely manner. I also get my thyroid medication from Canada as I cannot use the generic form of it, either. I lasted three days on the generic versions of both medications. Just not worth it for me.

Hi...I have the same problem I'm been taking norvav prescription and have palpitations and skip heartbeat. The doctor change me for another different one but I still have the same problem.

My BP has been high for several years but has been only modestly treated while I cared for my wife with chronic COPD with complications. In March 2012 she passed away and the BP really spiked. I began aggressive treatment in April 2012 and am now on 5 medications for it amlodipine, losartan,carvedilol, doxazosin and hydrochlorthiazine. The amlodipine, for me and like others here, has been a mixed blessing. I helps bring the BP down but ankle swelling, drowsiness and all the other negatives made me ask my doctor to take me off it.

Particularly bad for me was the fatigue I felt for the first part of the day after my morning dosage. I am now on 2.5 Mg for 2 weeks. But what I want to relate here is the positive effects of diet and exercise and weight control on BP for me as well as mediation to relieve tension.

Along with the meds. I have had really good results from eating a diet high in the nutrients that most affect BP potassium, magnesium and calcium along with plenty of fruits. Moderate exercise has to be an important part of the mix. I am 78 and find walking more difficult as time passes so I ride a bicycle now. I bought a bike with an electric motor and LiIon battery to calm the winds and level the hills so that I can ride at least 6 miles 3 days a week. 5 lb weights lifted 50 times for each arm and 10 modified situps are the extent of my exercises. And mediation to calm myself.

My doctor tells me that I will have to take the medications the rest of my life but without the self help described above the meds. are simply not enough to do the job for me. I hope my experiences aids some of you on this forum. Your comments have helped me realize that I am not alone with my BP worries.

What is the solution, does a slight swelling of the feet do damage? I am on the Amlodipine besylate 2.5 I hate meds, can't take Statin either and one of the side effects is fighting calcium? How can an old person try to help their Arthritis? Meds are crazy

I've had the same experience as Ken and Judy L in that I was prescribed 5 mg Amlodipine for being slightly hypertensive (140/90). After going on the drug my pressure is down (125/75), but it has had the miraculous side effect of reducing my migraines by about tenfold!! It has been an unexpected life-changer. I used to take Imitrex 2-3 times a week for my migraines, and now it's down to about 1 every two months. I also take a 250mg/day Magnesium supplement as well.

I'm surprised that more people have not be prescribed or tried amlodipine for migraines since so many people suffer from them, and it's made such a HUGE difference for me and some others it seems.

I've not had any negative side effects... I run about 20-30 miles/week also, and I often would feel faint about 4 hours after a run. The amlodopine seems to have prevented that as well, since it hasn't happened since I started taking it.

I am 73 and was prescribed 5 mg of Ampoldipine a few years ago for slightly elevated BP to accompany my Losartan/HTZ of 100/25 tablets. I recently was diagnosed with type 2 diabetes, having gone from a fasting 105 blood glucose to a fasting 124 in just six months and I have not done anything differently during those months. I have been experiencing some other autoimmune problems, but I am very suspect of the Amplodipine because all of my glucose levels have registered below 100 with my new glucose meter. This morning, I started with a 99 BG which immediately rose to 123 after taking Amplodipine.

The package insert from my pharmacist states that, "Use this medicine with caution in the elderly; they may be more sensitive to its effects." And drug.com states that "Amlodipine may cause hyperglycemia or increased blood glucose levels." I will retest the next few days and then call my geriatric internist with this information. He wasn't very happy when I stopped my Pravastatin two months ago, but I strongly believe that statin drugs can cause diabetes--and many documented studies agree with me.

SalW, I encourage you to do some research about the benefits of green tea. I have diabetes and have been drinking jasmine green tea for the last few weeks and I noticed my blood sugar readings doing much better. So, I looked up the benefits of green tea on the internet and was pleasantly surprised to find out it really does help with blood sugar regulation, as well as many other great benefits! I'm not giving medical advice, simply encouraging you, and others, to investigate the benefits of drinking green tea. Blessings and best wishes!

I am 68. I am taking amlmdipine 5 mg since march, 2009. My bp shot 160/110 dr. advised me to take this drug od. I was in Oman for 2 years when returned had problem in sex drive. When asked a dr. advised to take sildenafil citrate tab. It worked but without sildenafil no erection at all. Then I stopped taking amlodipine for some time and I had no problem intercourse.

I felt that my bp may be high so I went to the dr. the bp was 160/100. He gave me amlodipine 5 mg od and atorvastitine 10 mg hs. Since I took atorvastatine my sex activity came to 0 even after taking sildenafil 25 mg. Yesterday I came to know that atorvastatine gives side effect in sex drive, I decided not to take the drug.

I have ankle swelling and eczema just above ankle. Though I do not smoke but some time smell cigarette like smoke in bed room and in closet. As per bp I have 140/90. Thanks for giving a chance to explain.

Have you had your thyroid checked? Hypothyroidism can cause high blood pressure.

Thank you, Sabrina, for the suggestion of Jasmine green tea. I started drinking green tea yesterday with only 1 tsp. Splenda but was shocked at my high 165 glucose reading. I have learned that I certainly cannot tolerate Splenda and perhaps all other artificial sweeteners. I hope to be able to tolerate Stevia, which is what I will try next--or just do without!

5 years ago, after seeing my BP was slightly elevated from stress, my late doctor took me off hydrochlorothiazide (I never truly got past the constant dizziness) and substituted generic Norvasc 5mg coupled with increasing my Atenolol from 12.5 mg to 50 mg daily. Before the Atenolol increase, I'd been suffering from migraines for roughly 45 years. I haven't had one since! My doctor at the time attributed it solely to the Atenolol increase (not the Norvasc). And at 5 mg, the generic Norvasc side effects were virtually non-existent (except for some slight tiredness). My BP the past 5 years has been steady in the 120/70 to 130/70 range.

I've gained weight over the summer and I'm under some heavy stress. In July, my current doctor checked my BP and it was 145/80. He attributed this to the stress AND my weight gain. He told me losing weight would help. I lost a tiny bit since July and I'm still trying. I had an appointment with him yesterday and my BP came in at 165/70. He told me to double my Norvasc to 10 mg.

Two questions:
1. While I've seen no serious ill effects at 5 mg all these years, after reading this thread, I'm worried about the increased dose. Today is my first day at 10 mg and I feel spacey, a little jittery and out of sorts. Will this pass after a few days or a week? Perhaps I'm being naive here, but I honestly didn't expect to have ANY side effects!
2. I'm also wondering today, is my doctor overreacting just a bit by increasing the Norvasc?

Any info would be greatly appreciated! Thanks.

Hi RichD,
If I were you, for the time being, get a good BP machine and check your own BP at home. Check it two or more times a day for a while and record it. If it is OK, then don't be concerned. Even stress at the Dr. office can raise your Bp a lot.

What I do is arrive at the Dr. office early and sit in a chair without the Tv on (if possible) and lay your head back and relax, close your eyes and picture your self on a nice beach. Take deep breaths too. Works wonders for me. I had very bad reaction to Norvasc (among others) by the way.
Good Luck

Hi GRD,

Thanks for the reply and all the good advice! Actually, that's exactly what I've been doing now, checking my BP at home. After 3 days of Norvasc at 10mg, I called my doc and told him I couldn't tolerate the higher dosage. I'm back to taking 5mg daily. The side effects are still there but not quite as frequent or as intense as they were at 10mg. I've been averaging around 140/75 on my home BP monitor, still a little high for me.

Also, I forgot to mention it was my psychiatrist who upped the dose. I'm finally seeing a new doctor (my brother's GP) early next week. I intend to ask him to take me off Norvasc altogether and switch to something else - perhaps a diuretic, which I've taken in the past. We'll see how it goes!

Norvasc Did lower my blood pressure a little, 10 points. This is the first medication that has had any lowering effect. BUT, My feet and ankles swelled after taking it for a month. Then one leg swelled to the knee. I was afraid if i bumped myself with all that edema I might get a sore that wouldn't heal and besides the edema was uncomfortable. So I weaned myself off of the medication. Some of us have elevated B.P's that require something other than medicine. I'm using the Resperate device with some success. It will lower B.p. when elevated, but it doesn't stay down all day.

On 9/26 I commented that I was diagnosed with type 2 diabetes which was a misdiagnosis after two failed fasting blood tests because I mistakenly took my blood pressure meds before the tests. When I was given a blood glucose meter, I realized that the 5 mg of amlodipine I took daily raised my blood glucose (BG) level by 24 points. I then asked my doctor for an A1c test, which turned out normal and I do not have type 2 diabetes. Amlodipine can cause hyperglycemia and raise BG in older people. I also purchased a home A1c test at Walmart for only $10, and the test was only .1 different from the one I took in my doctor's office this week.

Generics are, by definition identical to the name brand (according to the FDA). Brands do not lower price when their patents expire as most folks just keep on ponying up for the brand name when they do not need to do so.

JW, generic brands may be called "identical" but sometimes are at best only comparable and often are not therapeutically equivalent. Just because the FDA says they are identical does not make them so. The generic must contain the same active ingredient as the original formula but often misses the mark. An outstanding number of generics are manufactured outside of the U,S--in India and Israel. For this reason, they do not share the same level of responsibilty as the makers of brand name equivalents.

They also do not have to update their warning labels when significant new risks emerge. There are many generic drugs saving people lots of money and working for them for which they are intended, but just log onto the problems doctors and patients have experienced with many, many generic drugs. For example, type in "pravastatin" and "Budeprion XL 300" on this site and you will see what problems can exist with generics.

Hi, I'm new to this forum and find the discussion very useful. I've been on Amlodipine for more than 5 years and my doctor said the brown pigmentation on both my ankles is caused by prolonged intake of this drug. He said it is called hemosiderin. I'm wondering if anyone else share the similar condition?

Hi: Can anyone advise what their doctor's gradual phase out plan was for discontinuing low doses of AMLODIPINE, (dosage and length of time).

I would like to get a general idea from people who have done this already so I have an idea of what I may be in for.

And YES I know the disclaimer - check with my Dr first - but I want to hear what others did anyway.

Thanks in advance for your information.

I have been on amlodipine for years and have taken every antidepressant out there. I read this site to see if it could come from my blood pressure med. I smell cigarette smoke lol too. I went off amlodipine and wow, no more depression. I started losartan, but it gave me heartburn so bad that I could not stand it even for a whole week. I had to restart amlodipine again and the depression came back. I will see the doctor on Monday Nov 20th, to find some way to get off of it.

I have mild high blood pressure and had no other side effects from either drug. Who needs more with depression. Your comments help me to investigate my own medicine. Thank you much

I recently insisted that my doctor stop prescribing amlodipine for me for my high blood pressure after 16 months on it. The side effects were awful and came on gradually and insidiously. During the first three months I developed Type 2 diabetes and had to start taking Metformin. Then a horrible itchy rash started on my lower right leg.

After many visits to two dermatologists and many creams, sprays, and foams later they could not tell me what the rash was from. I also experienced fatigue, leg cramps, lower back pain, dizziness, insomnia, throat tightness,and horrible swelling in my ankles, lower calves and sometimes feet. When the leg rash began to spread to my left leg and was itching out of control, I found this website and thank God found out I was not alone with these symptoms.

I am still taking Diovan HCTZ and atenolol for my high blood pressure with minimal or no side effects. After one week off of the amlodipine all the horrible side effects stopped. I hope this helps someone else out there who may be itching out of control and wearing long pants all the time to hide that horrible rash. Talk to your doctor and tell him/her to get you off of amlodipine IMMEDIATELY !!!

I have been on lisinopril for a couple of years 40 mgs and then lower to 20 mgs for the past 6 months. Two months ago 5 mg of amoldipine have been added and within one and a half month My libido has basically gone to zilch. No other real side effects. I took myself off of the amoldipine for a month to see if it was the cause. My lower pressure number went up a bit but some of my sexual desires have return but not all. I have resumed the 5 mg of amoldipine but am looking for a substitute to help reboost my libido. Any thoughts on this?

Melissa;

My husband has the same issue - seems to be a side effect to the medication. I don't like it - but like having him around more than I miss the romance. It takes work to fix this and there is no easy answer. He can't help it. Take it easy on him and try to work on the psychology of the romance together.

How long after stopping the Amlodipine did your depression last? Because I have been experiencing the same side effect, I just want to know when I will be normal again.

I am 82 and have been taking both a beta-blocker and Ca channel blocker daily. I seem to tolerate them well?. I have had borderline hypercalcemia for years. I doubt that it has anything to do with the BP meds. My endocrinologist did tell me to stop the HCTZ, I think because of kidney stones, also, to drink lots of water. They thought I may have hyperparathyroidism, but test is negative. I was told a few years ago to stay off extra Calcium, like Tums.

If anyone knows a good diet for hypercalcemia, that works, I would like it. I do work out at the gym, mostly in the water. I, also, had a very bad cough with much phlegm a few years ago. It was from a BP med. can't remember which one, but the med. literature said it had a side effect of a dry cough. Mine was far from dry, I even vomited phlem. Dr. did not believe me, but found out she was wrong. I am now pursuing the treatment for hypercalcemia and also get a lab repeat of PTH enzyme.

I feel like a medical ping pong ball at times, but I think, I am in good shape so far. I refuse lots of meds., also have the pharmacist do print outs of side effects. They are not necessarily correct, but a start.

I am on 2.5 amlodipine morning and evening. I want to stop taking it without inducing rebound hypertension. Can anyone suggest how. Should I halve the morning one for a while, then stop it, leaving just the evening?? Any suggestion would be appreciated.

I have been taking Amlodipine since 2009, as well as Lisinopril. For quite some time I have been having swollen ankles,as well as my calves. My feet got where they would hurt so bad I could hardly walk, they even kept me from going to sleep at night they hurt so bad.

I went to the doctor last week and told him about my problem, he said he had just talked with a heart surgeon recently, the surgeon told him that he didn't know how many people he had kept from having heart surgery just by taking them off Amlodipine.

My doctor said he could help me, he took me off the Amlodipine and put me on Hydrochlorothiazide 25 mg, the next day the swelling had lessened. I seem to be improving. The Doc also asked me to keep a record of my blood pressure for the next month, seems like its been all over the place. 158/58 tonight He also did a blood test to check my kidneys. They appeared fine in the test results.
I wish I knew how long it was going to take to get this stuff out of my system. I go back to see the Doc on 3/14.

I am 49 and this the first time being on high blood pressure pills. It is 5mg of Amlodipine (Norvasc) I now have rashes on my arms and hands where I have never before. I have lost approximately 20 pounds, changed my diet and my pressure is on average 132-135 over 82 - 85. The doctor does not want to remove the medication. I am researching other doctors and looking for a holistic approach to treat this blood pressure concern. Any suggestions?

I have been on amlodopine for 2 years, I have no sex drive at all.This is terrible! I'm so glad I found out the benefit of vitamin D. I had no idea that vitamin D lower blood pressure. We should start taking our health in our own hands. Look for healthier ways to help ourselves.

I am 58 and in excellent health, other than mild hypertension 150/90. My doctor placed me on 5mg of Amlodipine about two weeks ago and now my BP is averaging 120-80. The only side effects I have noticed in this short time period is occasional very mild headaches that normally are not enough to require meds and weight gain. I am 6'03" and normally 222-227, but I have been at 230 consistently for the last week or so and I exercise almost daily. Otherwise, I guess I am lucky and reacting properly with this medication.

I was glad to read this and hope it proves out for me. I quit all my other BP meds because of severe breathing problems (I have COPD to start with) and went to RESPeRATE which seems to be working for me. The only BP med I continued to take was 10 mg of Amlodipine. Suddenly my feet, ankles and sometimes up in the calve have been swelling, and in addition, I have what appears to be petechia on both of my feed. I have cut my Amlodipine back to 5 mg and am hoping that will help with the swelling.

While in Spain we went to Gibraltar just a shopping trip, the visit 4hrs total. On the way back to the coach I (73yr male) felt a tingling sensation in my legs, I sat down and had a look at my legs and they both were skin was red from ankle to just below the knee. It feels like an allergy. The question I'm asking is it okay to take antiestimem with taking Amlodipine, WFB.

Been taking 5mg Amlodlpine daily since 14th February I take one a day in the morning but by the evening I have a irritating cough, could this be my medication?

I was on amodlopine for several months. My BP started to raise and doctor added metropol and was on a very small dosage. Lost lots of weight (almost 39 pounds) and found my bp one day after I almost passed out at 99/56! My doctor took me off of amoldopine completely (no weaning) but stated to continue metoprolol however if my bp would rise to anything over 140 over 90 to take 5 mg of amolopine.

Well I got another doctor during this and the new doctor was impressed with my bp readings that he took me off everything! Well about a week later bps started going to 150/90 and I started feeling dizzy. I switched doctors again and went back on 5mg of amolodopine as first doctor suggested. Now it has been almost three weeks and feel periods of feeling great to then lows and feeling dizzy. I have been taking my bps regularly now since I will be seeing doctor Monday and readings have been in the 118/80 to a high of 136/98.

I used to feel ok on the amolodopine but now all of a sudden I feel as though I am getting side effects. Is it possible that this dosage of 5mg might be too much for me also? I am planning on losing an additional 10 pounds and hoping that does trick to get me off of the meds. Also I am in childbearing years and know that this med is unsafe. I am planning to have my doctor switch me to another... Disappointed that the medication that I once seemed to have adapted to is now making me feel lousy!

I was put on Amlodipine 5 mg for two weeks with olmasartan. The side effects are as below
1. Loss of libido erection and premature ejaculation
2. Dizzy and lightheaded feeling and loss of balance
3. Slight shortness of breath
4. Dry cough
5. Hallucinated dreams
6. Fatigue and sweaty

The drug increases anxiety and depression in people already having an anxiety disorder. It increases heartbeat with the slightest exertion. When you go to the Docs office and are waiting the waiting time apprehension can really play a havoc and this drug enhances the same effect. It enhances the Whitecoat effect. When the doc takes your readings it is bound to be high. The result you get more prescription.

In my case a normal 130/60 which I had been maintaining for several months owing to good diet, exercise, juices and relaxation techniques were disrupted by careless prescription of Ketorolac and several other NSAIDS and cold medicines by the doc. It spiked it up to 180/120. That was the reason when i went on the Amlodipine.

I have quit it after two weeks of usage. Cut the dose in half the for two days and stopped. I fee things returning back albeit slowly.

When you confront docs about the practical side effects, the first explanation they give you is the drug is perfectly harmless like a choco candy and you need to trust the docs prescription like your mothers home made cookies. I asked the doc specifically about sex-related issues and he assured me as to the contrary. He got angry when I told him that the BP meds were causing side effects and accused me of imagining them after reading it from the internet.

If there are safe alternatives to BP drugs just follow them. Taking them is akin to selling your pair of eyes to purchase an expensive picasso art.

PEOPLE'S PHARMACY RESPONSE: Sexual side effects such as ED are supposed to be less common with amlodipine than with some other blood pressure medicines such as diuretics or beta blockers. But that doesn't mean it couldn't happen.

my husband is on 5 mg of amlodipine and has severe leg tremor in his left leg--I had read in Life Extension book that calcium channel blockers can cause tremors and in fact Parkinsonian like symptoms. To-day a neurologist diagnosed early symptoms of Parkinson disease. Has any one else out there had such symptoms when taking amlodipine? He also gets leg muscle cramps in both legs on a daily basis, usually in the early morning. Thank you.

Did you know a heart attack could be prevented? I was rescued by paramedics who gave me 4 aspirin, and 2 nitoglycerin. When I arrived at the hospital, I was given morphine immediately. Since then, I have been taking 10 mg of Amlodipine daily since March 20, 2013 with very little side effects. I have slight dizziness at times. I always take the meds with food or on a full tummy.

I was diagnosed with Tachycardia (rapid heart rate) early March ( following my would-be heart attack scare) and placed on 3.1 mg of Coreg twice daily to slow my heart rate/lower BP. Even though I did not have a heart attack, I was placed on heart meds to help my heart. Now I am being waned off the Coreg (now I take one each night at bedtime). I am weary after reading all the negative posts. Since I had to stop all caffeine/soda, I believe my Amlodipine side effects to be minimal. I am forced to drink plenty of water, and use flavor enhancers like Milo to make water more exciting. I will keep everyone posted. But, so far, I love this medicine.

My problems began when I was placed on a water pill (maxide) for slightly elevated BP. After 2 days, I had no potassium, and found myself in ER with heart attack symptoms. At that time, I did not know water pills do not mix with heart arhythmia issues. Long story short, I did not have a heart attack. Regaining my strength, however, has been a slow process. I am finally feeling good again.

Hope this posts helps someone!

JB

I've been on 10 mg of amlodipine since 2007 and in the last year I've experienced three bouts of insomnia.. It will come without notice and leave just the same. I'm currently in a bout right now and went to see a sleep specialist. During the initial interview, as I was telling her what meds I took, she said the amlodipine is a "sleep Dr's enemy".. When doing research on this drug I've found others who have had this problem as well.. I would be curious to know if of you have experienced the same thing.

Brian, I have been on 5mg of this med for 30 days now. Although I have not experienced insomnia, I have noticed that my sleep is very easily interrupted and it is hard to go back to sleep. Prior to this, I could sleep through a hurricane and if awoken, could go back to sleep at a drop of a hat. I just saw my doctor last week for a follow-up on the initial Rx, all in all, I can't complain too much about the med, it has brought my slightly elevated BP (140-150/90) into the normal range, 120-80. A few minor side effects, most have subsided. The one that remains is the minor sleep issue and a slight problem with water retention (not at my ankles). I normally weigh 225 +-, and now I'm at 228-230 regardless how hard I work out. As they say, the overall benefits of the medicine outweigh the side effects. Lots of BP meds out there, find one that works for you.

I am trying to find out if amlodipne is causing me to have very warm red feet.

I started the regular norvasc with benzapril back in 2007 Had to change to separate pills because of price They are both made by AMNEAL.

The benazepril is 20mg and amlodipine 10mg. Shortly after my feet started getting warm. Dr thought nothing of it but now few years later they are very red when i get up of a morning and get very warm . DR SAYS DON'T THINK IT IS MEDICINE BUT IT IS RUNNING ME OUT OF MY MIND.

Do you think it could be the amlodipine or the generic stuff? I have got to find out.
Marlene G.

I have a hiatal hernea and have been taking Amlodipine 5 mg along with Benazepril 40 mg (both once a day) for 3 weeks now. I had not had any problems with the hernea for at least the last 6 months but ever since I started taking the Amlodipine and Benazeril for hypertension, the hernea has been acting up terribly almost every day. It even woke me up one night because the pain was so intense. Has anyone else had these symptoms with these medications? I really don't know what to do - my blood pressure was very high when I went to the doctor so I know I need meds for it but this pain is really awful. Help, please!!!

There are a lot of questions but where are the answers? Some of these questions are the same we have but we need answers!

I have been taking Amlodipine Besylate 2.5mg for my BP, and Livalo 4mg. for my Cholesterol for 2yrs now. Ever since then I gained 30lbs. and I have what you call it a "moon face" ( swollen all over) from my feet all up my body. It does not matter either I exercise, Zumba 3X a week and gym 3X a week and eat the right food...still gaining and feel swollen up every time I wake up in the morning! I also started getting really dizzy and loose balance frequently with the severe headache all the time. It seems WE ALL have the same side effects taking same medication (Amlodipine Besylate)..

What I did for myself just to experiment if all these pain I'm experiencing will at least reduced was: I took my med. 2X a week and it seems to slow down all these side effects I'm feeling.. My Dr. is okay with it as long as my BP is okay. But my Cholesterol still too high !

There are so many BP meds on the market, why does your doctor keep you on this med? I take 5mg nightly along with Lipitor for my slightly elevated cholesterol level. I have a tiny amount of water retention, according to my doctor, that amounts to just a couple of pounds, no other side effects. I would suggest either new BP meds or a new Doctor, without delay.

I have been on Amlodipine 5 mg for 10 weeks. I notified my cardiologist within a week after starting this med that I was having skipped beats and rapid pulse. (I was already on Toprol XL, 50 mg BID, Cozaar, 50 mg BID and have exiting arrhythmia-which was under control) After weeks of notifying my doc, they put me on a Holter Monitor. The results were as I reported that I was having a variety of cardiac episodes. I was then told to see a specialist to
place me on an anti arrhythmic. Then had blood work which showed elevation in my liver enzymes. Again, I notified cardiologist and was told to have it repeated. Labs were normal prior to start of Amlodipine. I passed on the anti arrhythmic.

What does it take to have the medical profession listen to what we are saying and experiencing? This morning I reduced my dose to 2.5 mg and will wean off and replace with something else, don't know what for sure.

I finally had my BP under relatively good control at 130/60. Now I guess we will find some other solution. Consulting with my EP tomorrow.

I am convinced more than ever that patients need to become more proactive, know about adverse drug reactions and also know what possible dangerous combinations exist. We need to become experts because no one cares more about us than us. This is one reason that the Peoples Pharmacy is our best ally because we can learn about the experiences of many other readers.

I have just reviewed some comments by Dr. Ray Strand, MD, who has written the book Death by Prescription. He says that "once the FDA approves the medication or a drug for use by the general public, they know less than half of the serious adverse drug reactions when that drug is released. It is just impossible to know them all. Well, they find out, and the next question should be, 'How do they find out the others?' Well, it's owing to you, the public, or what I call in my book, 'the great clinical trial.' It is you who finds out."

He continues, "The reporting of adverse reactions is a voluntary reporting system. Less than one percent of these adverse drug reactions are really reported back to the FDA, because doctors and hospitals are not required to report them back. It is voluntary. Then, it is reported to a committee in the FDA that has no authority. Once enough of these red flags come in on a drug, then they'll send it back to the original committee that approved the drug in the first place. I do not feel that they have an unbiased representation when they look at this. That’s why over 99 percent of the time all that happens is a change to the drug label or what we call a package insert. This usually goes unnoticed even if they send out a "dear doctor" letter warning doctors about these drugs and that they better be careful here. There have been studies that show doctors don’t pay much attention to that. So it’s not a very good system."

I believe that doctors maybe are doing their best but perhaps not enough in listening to the problems patients are experiencing with their medications. Pharmaceutical reps still carry a lot of "persuasion" as I noticed on the last visit to my husband's cardiologist's office. Being wheeled in at lunch time was a huge bowl of shrimp on ice, fresh fruit and other glorious goodies. I wonder how often adverse drug reactions are discussed!

I have been reviewing the posts on this site since I started taking Norvasc about two months ago. I have found this site to be very helpful because we, as patients and consumers of this particular medication, can share our stories, pro-con. This information helps us make an assessment as to whether this particular medication is working for us or not. As with all medications, the information sheets will states words to the effect, "Your doctor has determined the benefit of this medication outweighs the potential side effects." That is a true statement, to a point. When I started Norvasc a couple of months ago, I experienced several slight side effects, nothing significant but side effects never the less. The best advice I read on this site was (absent extreme side-effects) to let it ride for a couple of months, allow the body to adjust to the medication. That is exactly what I did and it is working well for me. I am only taking 5mg and my BP is perfect, b/t 110-70, 120-80.

The point I am making, and this is my opinion, give this medication a little time to work. If you experience extreme side-effects, such as edema to the lower extremities, serious palpitations and the like, MEET WITH YOUR DOCTOR FOR A FOLLOW-UP APPOINTMENT AND TELL HIM/HER WHAT IS HAPPENING TO YOUR BODY.

I am frustrated when I read folks on this site complain about extreme side effects, and either just complain on this site, OR go to their doctor and report they are blown off. If a doctor is NOT listening to you, fire their ass. Doctor's are a dime a dozen. There are tons of BP meds, but it is imperative that blood tests be taken after you start the meds to make sure there are no side effects you are not aware of.

Example, my wife was placed on BP medication last year. The first medication had an adverse effect on her potassium level, it was ONLY discovered in a blood test taken after the Rx was issued because the doctor wanted to make sure everything was fine. It was not, so he stopped that medication and gave her a second Rx. That medication was stopped about 7 days later because my wife experienced lethargic demeanor. The doctor stopped that Rx and gave her a third BP medication. That medication worked !!! MY WIFE HAS AN EXCELLENT DOCTOR WHO DOES PROPER BLOOD TEST FOLLOW-UP WITH EACH NEW Rx AND HE LISTENS TO HER. And trust me, my wife would never accept a doctor who did not listen, NOR SHOULD YOU !!!! The great news, my wife retired two months ago and now she is off BP medication as it returned to normal.

SalW:

Your suggestion to call the FDA to report adverse reactions to a drug is a good one. I did just that a few years ago when I experienced harmful tendon problems from an antibiotic my doctor had prescribed. While talking to the gentleman at the FDA, I asked him if anybody else had reported this antibiotic. His words were "Do not say it came from me, but we have more complaints about this drug than any other." Has this drug been taken off the market? No. Has any type of warning gone out. No.

When I tried to get help from more than one doctor afterwards, they went from shrugging their shoulders to giving me a long lecture as to why this is not true. It does not take long on the internet to find literally thousands of people who have been greatly harmed from this still commonly used antibiotic. I still have some tendon problems after taking only 4 pills, but at least I did not have to be operated on nor have I ended up in a wheelchair as so many others have. So much for the FDA. They have done nothing and people continue to be greatly harmed. And maybe this is a partial answer to MikeP. It would be nice to find a doctor like your wife has, but it is not always possible.

I went to several doctors about the antibiotic problem, but I ended up having to take care of it myself. I have Fibro so used some Fibro tricks to negate the tendon harm better than many others. I did not mess around when the generic Norvasc bothered me either. Yes, one can try giving the drug a chance, but when you know that something is not right for you, listen to your body. I got off the generic pronto. Am on the name brand again and doing well. I take it at bedtime.

Thank you so much for these comments...I thought I was losin" it!
Especially the smell of smoke..the oddest thing in my life!...now I know it's
definitely the drug...big relief. I have almost all the symptoms....swelling achy feet,
shooting pains all over my body, swollen hands(keep dropping things all the time) achy knees with stabbing pains, shortness of breath, weight gain, no energy, depression .....this can't be a good way to live! For me these are not side effects....these are Effects.

I'm on 5mg of Amlodipine, the third HP med I've tried....now what?
I'm going to make an appt with an acupuncture & herbal Dr. today, will post again if I have any good results.

I will try to make this short. I've been on lisinopril for almost 18 years and Norvasc was added in the last two years. Until last month I've had no significant problems with either drug. Just luck I guess. In the 18 years I've moved from 10 mg of Lisinopril to 30 mg Lisinopril and 5 mg norvasc.

These increases were due to my ignorance of: NSAIDS and BP which happened on two occasions and the solution was to increase my dose with out getting to the root cause of the problem. The last event was my failure to recognize that grapefruit, more than twice a week in my case, can significantly multiply the affect of norvasc.

This mistake has resulted in my now having problems with my heart rhythm. Bottom line... you need to be well informed... In theory I should still be on 10 mg of lisinopril. Good news is weight loss, exercise and diet can help you reduce or even stop your medications. Unfortunately we all have different problems, we just need to be smart about the treatments and visit sites like this for some form of hope. Good luck to all! I plan to be off BP meds in 6 months.

Thankfully I stumbled onto this site. I am taking Amplodimine for 3 months. I have also smelled the cigarette smoke several times and actually walked around house/yard to see if I could detect. Nothing! I thought I was crazy. I also have a chronic dry cough that is annoying and uncontrollable when I begin to eat. Linisopril caused such severe coughing I quit taking. I am now taking Atenolol and Losartin. I hate taking 3 medications to control BP. I want info on foods or natural methods of control. Where to look for info???

Yes! I am aware there are lots of BP med. out there. This Amlodipine and Livalo I am taking now are my 3rd med. out of diff. BP and cholesterol med. I tried in the course of 2 yrs. now. I probably tried most of them already. After I stumbled to this website I learned that everyone has the same side effects. What me and my son did was: cut the peel in half and only take 2x weekly instead of everyday. "it works for me and my son" not suffering on severe headaches, dizziness and less feeling off balance. I also added 1 Aspirin (325mg.) every night OR in the morning after breakfast. Hopefully, soon I will lose this water weight and not taking all these med. I'm the kind of person doesn't rely on medication if I can help it. My Dr. monitors me every 4 months and Blood test too. I also started taking COQ10 (one capsule) everyday, Fish Oil, Iron pill, and Vit. E once in awhile... Good luck to all of you! And keep everybody posted…

I have taken Norvasc for a month. Sometimes I have some ankle swelling but as I live in a very hot country, I am not surprised by this. It does not stop me running or swimming or working on my feet all day. I am 58, slim and eat healthily. One of the side effects that others don't like, drowsiness, has come as a blessing to me. For the first time in my life, I am having afternoon snoozes and sleeping at night.

5mg of Norvasc has not altered my blood pressure much but what it seems to do is stop it shooting up at times. I am now beginning to be more disciplined with the life style changes I know I must make in any case to stay healthy but will keep taking the meds and feeling very thankful that they are available as I don't want to have kidney failure and fatal stroke like my Dad did in his mid sixties after suffering with BP that went up and down dramatically. Of course it would be good to reduce the dose or just to take a diuretic in time, but I've got to work towards that.

I had hypertension for over 20 years that I was overweight. After losing the extra pounds the hypertension is gone. Needless to say the docs only wanted to give me drugs, which I took, and every one had side effects. Most all the affects have been described in the above comments. The smelling of cigarette smoke is still present today. It is real. We are just so sensitive to it that we can smell it from 2 blocks away. It is not so much a smell but a sensation. Often I can find the source but not always. I am on other medications that I believe to be the cause of the hypersensitiveness.

I was prescribed amlodipine for hypertension and took it for about a month until the heart palpitations that took years to control came back. I have stopped taking the scrip for about a week now and it seems like my heart rate is low and the palps ares still hanging around. Anyone out there try this cold turkey method? Any idea how long this drug stays in your system?
Any feedback would be welcomed

My doctor prescribed Amlidopine for my blood pressure 2 months ago! After a short time I noticed that my energy level just dropped and I felt like a Zombie!! I also noticed that my heart rate had dropped to a very low level, sometimes as low as 37 bpm!! The GP does not tell you of the possible side effects of taking this medication and seems to hand out tablets as if they are sweets!!

Whenever I tell my doctor how I feel, he never once checked me with even his stethoscope! I never had such a low heart rate until I started taking Amlidopine tablets!! I have decided to stop taking them and will see if my heart rate improves!!

Peoples Pharmacy response: Be sure to let your doctor know that you have decided to stop taking your medication. If you are unhappy with the physician's approach, as it seems you have every right to be, you might want to look for a new Dr. With luck, you may find one who listens to the patient.

My doctors put me on metoprolol 25mg 3x/day, I reduced to 2x/day and she said in order for me to get off the metoprolol I have to be weened off so she has me taking metoprolol 1x/day and amlodipine besylate 2.5mg at bedtime. I am terrified to take this after reading some of these posts. I have gained a awful lot of weight since taking metoprolol, anyone else gained weight from this?

My trainer at Wayne State university said I am probably not able to lose as a result in the beta blocker keeping my heart rate so low. Can this be true? geez my main concern at the moment is taking both these BP lower medications, what are the dangers/side affects.

I have being taking Amlodipine for six month for BP. I have had swollen ankle and swelling problem. Do you think it's the amlodipine?

People's Pharmacy response: Amlodipine can cause swelling of the legs.

I cannot figure this out as I was on lisinopril for a year but lost our regular doctor, the one taking his place put me on minoxidil causing my ankles to swell, my tongue to swell, my testicles to swell, dizziness, and other side effects, changed doctors, who put me back on lisinopril for about a year, now he says I need to try amlodipine besylate 10mg, no mention of CHLORTHALIDONE, and I did ask, and did also ask does this amlodipine have a diuretic.

Answer was no, so I am not the doctor but I know that now I will have the swelling ankles and legs again as his assistant has already mentioned so what do we do? so fluid retention, dizziness, fatigue, swollen tongue, swollen testicles, and they are trying to keep you healthy. well!

was on atenenol for many years with no side effects, had a stroke 7 months ago because of elevated bp was put on generic norvasc 10mg, diavan and meteropol and blood pressure is sometimes way to low. Norvasc has caused my gums to swell and my leg and arm feel feel numb at times. If I move to quickly I get vertigo.

I told the dr. about these side affects and she said that they were probably more because of the stroke. not to read so much about what is posted on the internet. She is taking me off the norvasc cold turkey and prescribed a water pill and increased my diovan to 320mg.

I asked her if she should wean me off of norvasc and she said it wasn't necessary. She said just keep an eye on bp if it gets to high go to the er!I am going to take 5mg for a few days with my diovan and meteropol before I discontinue norvasc cold turkey and than start water pill. Has anybody gone cold turkey off of Norvasc?

I have been taking amlodipine 10mg for approximately two years. And now 20mg of Lovastatin due to rapid rise in my cholesterol. Before ever taking amlodipine, my BP was maybe 139/70 or lower. Since I've been on it consistently, my pressure is always high, between 130 to 140+/80+ (rarely 120/70). The cholesterol declined from 300 to lower than normal range within 3 weeks on Lovastatin.

I wonder if the amlodipine caused the spike in HDL. I too, have been smelling cigarette smoke which is not there. My toes feel as though they're going to burst open from pressure and pain, I can't sleep for long periods, I make trips to the bathroom no less than 3 times during the night, each night, my head feels strange inside, and I'm moody.

I asked the doctor to change it, but they refused with no reason, one PA actually told me (with an attitude) to "stop taking it" after I said I would like to try exercise and nutrition to try and get me to the point where I could possibly get off the meds.

They never told me about the consequences of BP spiking when abruptly stopping amlodipine. Why is this? Seems the meds make you worst off than you already were, in some cases.

Melatonin is a natural sleep aid that works for a lot of people. You can get it in pill form or buy dark cherry juice. Either should be taken 30 minutes before bed time.

I am on 360 mg of Cartia XT (180 2x a day) after trying Lisinopril (wound up in hospital with allergic reaction and anaphylactic shock), Metropolol (made me almost go bald and severely depressed) and I cannot take diuretics, due to gout... I notice that PP seems to think diuretics are the best answer, but I simply cannot take them... I am too afraid to try another ACE Inhibitor (or even and ACE II!) But my bp is still about 160/110... anybody? Graedons? I am terrified as I am only 56 yrs old and wonder what my future will be like (If I even have one) Thanks to anyone

I am sorry to tell you that, at least in Ohio (Thank goodness for states rights, eh lol), Medicaid pretty much decides who you will see. There is only one Internal Med dr in my county that accepts Medicaid (they only pay a GP about $20 for an OV BTW) and that is who I am stuck with.... I am feeling so sick on this highest dose of Cartia XL available and BP still at 156/110 (at 56 yrs old BMI 26, cannot exercise much) that I may drive up to Cleveland Clinic when I can get in next and see a Cardiologist (they see ppl no matter how much $$ they have, you know, like civilized countries do--so Ohioans end up paying for it anyway, but I refuse to lay down and die for $$, I wasn't raised to let ppl do that). It is a waste of money, energy and misery for poor ppl in this country that our citizenry cannot see that health care for all, is a human right.... I will get off of my soapbox now and throw in that I , too, worked for the county govt for 25 yrs, Until I was hit by a drunk driver, and, I have an MSW....but no one, educated or not, rich or not, sick or not, working or not---deserves the kind of "health care" we Americans have come to put up with and it is a pathetic shame. Thank you

Anyway (ahem...) my suggestion is that you try to find a place like Cleveland Clinic (they will see ppl from out of state) or Mayo Clinic or even go to Canada (where you will have to pay, of course, but your meds won't leave you homeless...) to get another opinion.... it is sad to say that a lot of bad medical students end up "caring for" the poor on Medicaid, in public clinics and the VA... but, as long as "doctoring" pays so well in the US, there will be ppl who attempt medical school, when they are not at all suited for it. Best of luck to you.

This forum has been extremely helpful! I had never put all of my strange symptoms together and tied them to the Norvasc (taking generic) before now. I have been on it for over 2 years. I thought I was losing my mind! I have had almost all of the Norvasc symptoms mentioned in other posts.


I do have one that has been really odd that I haven't seen posted. It would help me to know if anyone else has experienced this. I get an awful pain in my upper right shoulder like a spasm. It will come and go, with no rhyme or reason and is not helped by Advil, some slight easing with a heating pad. Sometimes it will last for hours/days, other times just a few minutes.

I have stopped eating gluten, eat mostly a Med. diet, walk fairly regularly. I mentioned it to my chiropractor recently because I thought it was related to tension but he told me the spot and pain I mentioned were the acupressure point and related response for when the liver is stressed. He called it a liver response.

Anyone else dealt with this? I have scheduled an appointment with my MD to discuss; I think I need to get off this stuff. It hasn't really helped much with the BP numbers and I am now also taking HCTZ for swelling.

Lisinipril caused awful mucusy cough/sinus congestion.
Thank you for any insights!

Since most of us are suffering, I hope this forum continues... every time I get a new notification, I think "oh, I hope it is someone that has a problem I recognize"--not that I want others to suffer... I just hope we can come up with some answers together and I feel less alone.... thanks so much to everyone for sharing...

My doctor started me on Amlodipine 4 weeks ago. 5mg morning and night. I started to retain fluid in my ankles after 10 days.

I have never had this problem. Now I have a rash on my legs that is red and swollen and it burns. After reading this blog I am convinced it is the drug.

I am going back to see my doctor. With all these side effects I no longer want to take this drug. I'm a bit scared to go off it on my own. I've had high pressure since I was 40 and in 20 years of taking BP meds never had this happen.

what have you taken before that didn't do this? thanks

First,Micolry..you have to call Medicaid and get info.and request to changeDoctor for you and your Mom..i have the same issues for my Special Need Son with Medicaid doctors. They need to be in Medicaid network or Medicaid lists before you go see another doctor or else they will surprisingly bill you unexpectedly amount of $$$!

Doing so..make a log everyday and how the effect of any medication feel..this is how i most figured out the side effects of my med. and also for my son.. this is how i feel if my doctor does not listen to my problems..I do too get 2nd opinion a lot! This really helps! Happened to me twice! Learned my lessons NOT to stick to only ONE doctor opinions when it comes to your health. I know it is a lot of works,but it is WORTH IT in the end:).GOODLUCK!! Keep us posted..

First all, This is THE BEST site ever created!!for people like us that takes THE SAME MEDICATIONS : I made few comments and side effects about my BP med. Amlodipine and my Cholesterol med. Livalo few months back. Ever since then, I read so much feedbacks and the same comments from diff. patients like me.

All that being said.. this is what I did to reduced all those side effects of my med. mentioned above: I started tapering to 1/2 pill a night on both of my med. TWICE a WEEK and started writing down and make notes on my DailyLogBook how I feel after the "tapering" effect.. I told my Doc. what I was doing and let him know the results. I NEVER felt better and feel normal again after few months now from the time I lower the intake of my med. I don't feel dizzy, no excruciating headaches, not feeling wobbly and no more lightheaded feeling and Most of All..muscle pain. My BP is in control and the best one for years, but I am not sure about my cholesterol until I see my Doc. again in 2wks. another Lab Test..I also take 100mg. of COQ10 and Fish Oil with my med..

Again.. Thank you all for the Responds and comments.. Good luck to All!! Keep posting: it help!!

To: SLN: Call your Doctor immediately, ask him if you can tapered your Amlodipine intake to 1/2 @ am and 1/2 @ pm. This is what happened to me too! I tapered mine to lower dose and feel the difference in one week.

My son also takes 10mg. Amlodipine and noticed, he is so puffy and bloated every morning he wakes up! I started tapering his med. into 1/2 pill and see the difference on him. Also I am going to request my Doctor and my son's to prescribe Water Pill. I have been told it help a lot and at the same time lower the BP too!

I will post comments if my doctor will let me take WaterPill in addition to my Amlodipine.. I gained 35lbs. since on my med too for 2yrs. now.. I hated it!! I am trying to lose weight but it seems not going nowhere coz of these med. GOOD LUCK to you!!

I used to take Lisinopril but the doctor 5mg didn't think that was helping to lower my BP so she put me on Amlodipine with helped along with Hydrochlorothiazide. When I was between refills my BP went high and so the Dr. prescribed 10 mg of Amlodipine. Sunday I had the worst swollen feet, I could only wear one kind of shoe. I don't know if maybe I should just go back to a lower dose of the Amlodipine, back to 5mg. I would rather go back to lisinopril, that way I wouldn't have to take two pills every day.

I'm otherwise healthy, I do Jazzercise, I haven't had soda for almost a year now! I drink lots of water. I don't want to be on this medicine forever.

while it is true that there are "many bp drugs", unfortunately, there are only about 3-4 classes of drug and if you are stuck on generics, even less than that....there are diuretics, beta blockers ACE I and II inhibitors and calcium channel blockers....if anyone knows of any drug that is not in those classes, please let me know....they all have made me feel like crap and I had an anaphylactic reaction to lisinopril (ACE I)....diuretics didn't work for me, beta blockers made me sick and half bald and now CCBs are making me depressed and swollen in the leg and belly...and, my bp is still mildly high...

It is really hard for me to exercise (I am disabled) and I am limited as to what I can eat, due to a colectomy...I just got the last opinion I am going to get at Cleveland Clinic (they see ppl on medicaid for free). I don't think there are a lot of options and Big Pharma is too busy making the next Viagra to bother.

Amlodopine.

I was given this an an alternative med since I had a rash with my first med. Altogether I have been on med for 4 years. I don't think my BP is all that serious considering all the side effects it is doing to my body.

I stopped smoking at the same time as being diagnosed and I walk all the time since I don't drive.

I have now stopped taking the amlodopine and am going to monitor my own b/p to see how fare after 3 months. I also have just been prescribed med for osteoporosis and I blame it for my hair falling out ..... so I have stopped it also.

Trial and error !!

Responding to Kate and anyone else who's tried decreasing amlodipine. I have recently tried acupuncture with cupping and thought we were doing well. Currently I'm on Bisoprolol Beta blocker 2.5 and Amlodipine 5mg. The doctor wanted to increase the amlodipine as readings were really high 180/105. I didn't increase the meds. went to acupuncture and readings were commonly 145/89 which for me is a GREAT improvement and one that I'd be happy to work with. Then we started reducing tablets by cutting off one third. That was about ten days ago. The last few days have seen me with sore heads and last night's readings were .... scary. 195/110. I'm interested in knowing if anyone else has a) tried acupuncture including cupping and b) cut down on amlodipine and had the bp increases. Does the BP settle? I felt so good in the first two weeks of the acupuncture ;-) and feel somewhat despondent today. Thanks for any response. And .. thanks for a great and helpful site.

Hello CE,

My mother is on Amlodipine 5mg and she gets these bad dry coughs at night and her ankle gets swollen too, can you tell me what old medicine your doctor gave you so I can tell my mothers doctor too.

I have been on amlodipine 10 mg for 8 years. my bp does not come down by much. I have gum problems that would not go away. Is there any other drug that I can use.

PEOPLE'S PHARMACY RESPONSE:

This is a discussion you should have with the prescriber. There are several options available. You will also find an overview of blood pressure treatment in our guide on this website.

https://store.peoplespharmacy.com/guides/blood-pressure-treatment.html

I stopped taking amlodipine on Aug 27, five days later I am still having the pain in my foot.

I stopped taking amlodipine on Aug 27, five days later I am still having the pain in my foot.

Anyone have swollen inflames eyelids, I started these symptoms about 6 weeks ago having taken Amlodopine 5mg for over 2 years, I have been off them for just over 1 week and all seems to be getting back to normal.

I was taking lisinopril for 3 years before that and developed an allergy to those ending up in hospital for 3 days with swollen tongue and restricted airways.

I am so relieved to read many of your comments. I started amlodipine, 5mg a day, a little over a week ago because benazepril was becoming less effective. After the first amlodipine, it knocked me out in the middle of the day as soon as I had eaten. I slept literally like the dead, though I had slept well the night before.

It did lower my blood pressure from the high 150s/90s to the lower 130s/80s, and I was glad about that.

I didn't experience any noticeable side effects for the next few days. But in the last three days I've noticed a tight feeling in the left side of my chest, and I've had intermittent depression that is sometimes overwhelming, like panic and despair in one. I've been depressed before, but I have never felt anything like this. I took an alprazolam for the panic and passed out for hours and awoke profoundly depressed (which has never happened with alprazolam before). This BP med is not for me.

Have been on amlodipine 5 for two and a half years. Suddenly my ankles and bottom of legs are swollen and feel cold. Doctor does not feel it is caused by medicine, just aging. (I am 63.) Is this normal?

I have read this site with interest! Primarily I have been taking brand name effexor 150 mgs for several months for panic disorder and anxiety. Nothing really helped me, however, I decided to continue with this medication to see what happens. Today I took my script in for Effexor and it was not until I got home that I realized that they had given me a pharmacy brand for this medication! I took one anyway and within an hour I was vomiting, felt very nauseated, faint, dizzy, vomiting, dry wrenching and a tachycardia, red in the face and generally shacking all over. I am going to take this back to the pharmacy and ask for my money back because I will not take this again!It is dangerous and needs to be investigated further!

Clappo Sue

my husband is on Amlodipine since 2009 and gradually got a lot of serious side effects, the worse being mental decline, confusion, lost of memory, drowsiness, total lack of energy and motivation of doing anything, depression etc. The doctors refused to replace the Amlodipine even though according to the newest and independent health info the accepted BP for his age, 70 and older is 140/90 for an otherwise healthy adult, and that he can easily get it just from Bystolic, some daily walking and supplements.

I took amlodipine for just one week and became very short of breath. Dr didn't think it was the amlopidine and ran tests to check my heart. Maybe he is right but it seems very coincidental that I was fine, took pills, and can't breathe! I have been off pills a week and I am still short of breathe. Any comparisons?

I am using Lisinopril 40MG for about 3yrs now. I have swollen ankles, cold hand and feel as well as sore painful feet. I have for the first time a rash around my neckline, and my top lip is swollen as if someone punched me in the kisser. I've used an ice pack with no results. I have an appt. with my medical provider April 15th for testing. I'll share the results with you later. I am a 76 yr. old African American. adding to the above mentioned side effects, I have also noticed irregular heart beat as well.

I started on generic Norvasc 3 weeks ago (a Friday). On Monday I saw my doctor for a follow up visit, and he increased my dose to 10. The next morning I woke up in a cold sweat, with racing heart and flushed skin all over my body. I freaked and went to the ER, but all my cardiac tests came back normal, so they thought it was just my body adjusting to the increase.

This past week the flushed skin has returned (although it's intermittent), my legs and ankles are so swollen I can't put gym shoes on, and it seems like the lymph nodes in my neck are swollen. I also seem to be much more tired since starting it than I was before. Most mornings I can barely get out of bed.

I see my doctor today, and I'm really hoping he switches me to another bp med!

I was diagnosed w/ hypertension when I was 24. I was fit, not over weight, healthy. In 2005, I was diagnosed w/ aortic stenosis. Calcification of my aortic valve in my heart.
I should say, my brother (+16 yr) had the same problem. Late 2011 a cardiologist added amlodipine to my Rx cocktail to keep blood pressure down. On the web it says amlodipine is supposed to "prevent calcification of the heart as an entity."

Fast forward December 2013, symptoms send me to the cardiologist again. My aortic valve is blocked 83%!! Needless to say, I had valve replacement, 2/10. BUT, they just discontinued my amlodipine & I feel 100% better. Others on the drug talk about being so tired. As was I. But just 2 days without it & I see the difference. Norvasc should b hx. It has not kept up w/ the other advances in heart medication.

I am taking Amlodipine (5mg) and also include calcium supplements in my diet. Read in the Livestrong blog that they should not be taken together and cannot find that information now. I have Rosacia, so the doctors say... maybe forever(?) and I think it might be caused by this combination. The calcium is derived from veal bones and is natural. Does anyone have information on this? My doctors think this is ridiculous but suggested I not take the Amlodipine to see what happens, and rely on my diuretic. I check my BP at home and have been on BP meds for 30 yrs.

I have been on Amlodipine for about 8 months. Over the past 2-3 months I have had significant hair thinning and loss. Especially around the front hair line (or at least that is where I notice it the most). Doing some research today, I believe this medication is the cause of it. Calling the MD tomorrow.

I have been on Amlodipine for about 8 months. Over the past 2-3 months I have had significant hair thinning and loss. Especially around the front hair line (or at least that is where I notice it the most). Doing some research today, I believe this medication is the cause of it. Calling the MD tomorrow.

I have always had kind of thin hair- but plenty of it. My hair has always kind of been "my thing". I am menopausal too and divorced (tho dating exclusively). It may be a vain thing to say- because there truly are many more horrible things in life that can happen- but it is very stressful to go through this.

I know your post was from some time ago- if you see this can you update me on how things have turned out for you?

I started researching amlodipine a few days ago after my fiance started complaining of symptoms after his GP increased his dose from 5 mg to 10 mg and we both observed marked swelling in one or both of his ankles. He has also suffered, at one time or another, marked fatigue, painful headaches, flushing and redness around his neck and face, twitching, restlessness, light sleep, coughing, throat irritation, and dizzy spells.

Since his dosage increased, however, I find it really bizarre that I have been smelling cigarette smoke too! And no one smokes in this home, or drinks. Others on here posted that and now I am really exasperated about that symptom. We are looking at lowering his dosage by 1/4s over the next month or two and starting a walking and weight training program, as well as upping magnesium and potassium intake, tossing salt, cutting caffeine out slowly, and generally lowering his stress levels over the summer by selling off projects and junk we are trying to manage too frequently.

We are also going to a couples counselor to learn to manage any communication issues adding to his stress (we are both Irish, LOL) and if THAT all does not work, THEN we will go back to the NAME BRAND version of any drug and try to get it from Canada as his insurance is ok, but not that great with prescription costs. We will notify his doc, who was only trying to save him money with the generic prescriptions but we are finally taking this seriously: no medication is ok if it can be linked with congestive heart failure and I read elsewhere on the Internet that Holland banned amlodipine. That is all the evidence I need to take steps to get him away from an calcium channel blockers of any kind.

Am on amlodipine and do not like the side effects. What is a diet that is helpful for HBP? I have friends in the medical community who feel that my primary care physician is overreacting to my BP readings. I am eighty years old and do not like the effects of palpitations, swelling of ankles and feeling foggy in my thinking. My BP is generally around 156/78.

People's Pharmacy response: The blood pressure you cite is high enough for a doctor to treat even under the new more lenient guidelines. A DASH diet full of vegetables, with very little meat, might get it below the cut-off. Learn more about it in our Guide to Blood Pressure Treatment or online: http://dashdiet.org/?gclid=CMOKmLiXyr4CFZBxOgodOTkAOg

I cannot do the DASH diet (It is a very good one, wish I could) because I have an ostomy and cannot each hardly any raw fruit or veggies---does anyone has any other suggestions besides that? THANKS

I have been on Lopressor (Metoprolol) since the 1980's. I always had white coat hypertension since a young woman. Dr. put me on Metoprolol in my early 40's because it was always high in the doctor's office. I also have had panic/anxiety since a young person. In 2013, Amlodipine was added because the white coat hypertension was so bad my pressure would go up to 180-200/100, but would go down when left the office. I told the doctor this, but still insisted on adding Amlodipine.

Since on Amlodipine, my fingers swell and my shoes get tight at the end of the day, but not bad. But, I feel so drowsy after taking these medications in the morning. On 5 mg Amlodipine, I was doing well for a while, but the white coat stuff always showed up when I went to the doctor. I would prepare for days before a visit because I anticipated my pressure would go way up, as it did. I would take both meds early and a Xanax so the pressure would be normal and he would not add any more meds. I feel so lousy all day long now, drowsy, off balance a bit, nervous, lack of energy and interest, flushing, sweating weak after taking the meds. I thought maybe it was sugar, and am having that checked.

Problem is that the doctors don't try any alternatives like biofeedback or meditation, and with the blood pressure not being monitored all the time, we can't take the risk as the patient to alter the medications daily according to the blood pressure. Sometimes, when I am doing a lot of physical work, my pressure goes way down. Metoprolol causes the heart to beat slower, so the up and down feelings continue daily and ruin a life. I am tired of doctors who just keep adding and changing medications. When told to check with your doctor, well that's a laugh, because it is impossible to get the right help even from the pharmacist because they always say, "check with your doctor". It is very scary and these medications are killing us and making drug companies rich. We are so lost out here, I am any way.
Michele

I have been taking amlodipine for years without side effects although now I see that it can cause dizziness and I do have balance problems. But all of a sudden my feet and ankles have swollen horribly. They are like play dough. I can press with my fingers and the skin doesn't pop back. It leaves an indentation. I've gone for an arterial doppler and a venal doppler but nothing showed. I'm taking a water pill but that doesn't help. Can Amlodipine start causing swollen ankles after years of taking it? I stopped the medication 2 days ago. No improvement yet. How long would it take for the swelling to start going down?

I've been taking amalodopina since 2010 and my feet are now swollen and ankles are nowhere to be seen. I also have a skin rash that doesn't seem to heal and this has been going on since I started taking this additional medicine.

The comments on this site are saving my sanity and more. I was diagnosed first with Peripheral Neuropathy, years later Diabetes2. Prescribed: Glimeperide 1mg for Diabetes, Enalapiril 2.5mg for high Blood pressure. Enapiril seemed responsible for sporadic coughing so was switched to the generic for Norvasc, Amlodipine Besylate.

I am now experiencing an extensive itchy rash on my legs, arms and patches on other parts of my body. Still coughing, metallic mouth taste, loss of taste all foods and drink. Swollen feet, infected? eyelids, excessive tearing and runny nose, vision change and thinning hair. The rash on my right leg has extended into the already peeling, scabby area of the neuropathy affected area of my leg and a wound opened.

I was given Antibiotics, Amoxicillin and Cipro. Dr. Suggested a switch to Toprol as a replacement for Norvasco I declined. Now all Meds including Antibiotics has been stopped. All symptoms mentioned including a state of confusion and a loss of balance are more dramatically intense than expressed. At age 90 I still love life. Now exploring, how to proceed?

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