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Thyroid Medicine Better at Bedtime

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Millions of people have an underactive thyroid gland. This is called hypothyroidism and is usually treated with synthetic thyroid hormone called levothyroxine. There has been controversy about the best time of day to take this medication.

To determine whether it makes a difference whether the drug is taken upon arising or at bedtime, 105 Dutch patients were randomized to take one capsule in the morning and one in the evening. One was levothyroxine and the other was placebo, but neither the patients nor the doctors knew which was which. After 3 months the patients were switched. When the code was broken, the investigators found that the measures of thyroid function in the blood improved with bedtime administration. Patients also reported feeling better. According to the scientists, "clinicians should consider prescribing levothyroxine intake at bedtime."

[Archives of Internal Medicine, Dec. 13/27, 2010]

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59 Comments

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Bed time levothyroxine boosted my energy level. Unbelievable.

Is levothyroxine the same as Synthroid?

PEOPLE'S PHARMACY RESPONSE: LEVOTHYROXINE IS THE GENERAL (GENERIC) TERM. SYNTHROID IS A BRAND NAME FOR LEVOTHYROXINE.

I have taken Synthroid for nearly 30 years. When it was first prescribed, I was instructed to take it at bedtime. At some point along the way, instructions changed to first thing in the morning, at least 30 minutes before eating. I'm switching back to bedtime, because that is far more convenient for me in addition to the research findings you report.

I've always taken my thyroid meds in the AM (levothyroxine) because it keeps me up at night. I hesitate to change to the evening so I guess I'll continue in the daytime..

I have appt next week to check this. I have changed from night to morning. Keep info coming!

That is interesting but I have 3 questions: Does that mean I have to wait 2 hours until after I have eaten or had any meds before I can take the thyroid pill? and Will it not keep me up during the night? Do I still have to take them with a full glass of water? I take Levothyroxine and Armour thyroid. Thank you.

PEOPLE'S PHARMACY RESPONSE: YES, YOU SHOULD WAIT 2 HOURS AFTER EATING.
YOU SHOULD TAKE THEM WITH WATER--AT LEAST HALF A GLASS.
LEVOTHYROXINE WILL NOT KEEP YOU AWAKE AT NIGHT. WE DON'T KNOW ABOUT ARMOUR AND WELCOME YOUR REPORT ON YOUR EXPERIENCE IF YOU TRY THIS.

The directions from my physician were to take the thyroid med. 1/2 hr. before eating or drinking. So, how would this work if I took the med. with my evening pills (for cholesterol, and 2nd calcium pill of the day)?

I could wait a half hour before having a bed time snack, but what about what's eaten/how long before taking the thyroid pill?

PEOPLE'S PHARMACY RESPONSE: DON'T TAKE THE THYROID AT THE SAME TIME AS THE CALCIUM PILL. IT WILL INTERFERE WITH THYROID ABSORPTION. IF YOU ARE TAKING CALCIUM AT BEDTIME, YOU MAY WANT TO STICK TO TAKING YOUR THYROID FIRST THING IN THE MORNING.

When I was originally put on Armour thyroid back in the 1960's, I don't remember any preference being given for taking it, or whether it should be taken with or without something on the stomach. It was only within the last ten years that a preference was given. So I have gone from no preference, to night and now to morning. I also have a question as "cak" above. The pharmacist's directions are "take in the AM on an empty stomach an hour before eating with a glass of water with an hour between other meds". If I switch to evenings or night then what? How long after eating? What about other meds taken in the evening?

PEOPLE'S PHARMACY RESPONSE: THE BEST RESEARCH ON THIS ISSUE INVOLVES SYNTHROID RATHER THAN ARMOUR. IF YOU ARE TAKING OTHER MEDICINES IN THE EVENING, STICK WITH YOUR MORNING REGIMEN. CONSISTENCY IS THE MOST IMPORTANT THING IN THE PROGRAM.

IF YOU DID WANT TO SWITCH, YOU SHOULD MAKE SURE YOU HAVE AT LEAST AN HOUR AFTER YOU EAT BEFORE YOU TAKE THE MEDICATION.

When I took my thyroid meds at bedtime, I experienced terrifying nightmares... Could this be caused by an increase in some type of brain activity fueled by the thyroid meds??

Would it not be better to have ALL the thyroid tests, t3 , t4, uptakes etc and also your iodine and iodide. I always felt my thyroid was not right but tests were normal. I then had my iodine and iodide tested and they were low. I am supplementing with iodoral and will see what the next tests show. I do feel better.

Levoxyl is what I take - please respond to the questions asked. Thanks

PEOPLE'S PHARMACY RESPONSE: LEVOXYL IS LEVOTHYROXINE. THE RESEARCH SUGGESTS IT WOULD BE BETTER ABSORBED TAKEN AT BEDTIME, AT LEAST AN HOUR OR BETTER TWO HOURS AFTER EATING.

I tried taking levothyroxin at bedtime several hours after dinner, on an empty stomach with a glass of water. Consequently I was up 4 times during the night to the bathroom and had difficulty returning to sleep. Taking the medication at bedtime did not work for me.

PEOPLE'S PHARMACY RESPONSE: IT'S SMART OF YOU TO FIGURE OUT WHAT DOES WORK BEST FOR YOU.

Yes - it is a generic

Following the blood test for my T3 and T4, I was placed on two thyroid medications by my doctor. I've been taking them in the morning - as instructed by her and the pharmacy. However, in all honesty - I cannot tell any difference in the way I "feel". I've always had a nice constant energy levels which actually increases throughout the day. When I mention this to my doctor, she insists that I continue this medication (the only drugs I'm taking by the way!) I will try taking them before bedtime - as it would be more convenient. Will be interesting to see if I experience any changes.

I generally tell people to take calcium at bed time to help with insomnia or nightmare issues. But this would preclude people from taking their levoxythyronine in the evening because of the parathyroid/thyroid switching action. I have not seen this fact mentioned in this discussion.

I personally don't see any difference when I take my thyroid meds, because I too have decent energy levels all the time. I do recommend that anyone with a low-thyroid needs to build muscle to bump up your metabolism. When I was lifting regularly I never had to take thyroid meds because my levels were fine, but over the last few years that I have not lifted I have ended up on medication.

I am a cancer survivor and my surgeon put me on levothyroxine back in Oct 10 at 125mcg. On Nov 10 he told me it was too high and put me on 100mcg. On Dec 10 I started having problems with my shoulders and my hips, on the 23 of Dec I could hardly move and on the 24th of Dec I took myself off and now I feel a lot better. The only other meds I take are one a day vits and fish oil1200mgs.I don't know what happened, but I think I was taking too high of a dose?

PEOPLE'S PHARMACY RESPONSE: THE PROBLEMS YOU DESCRIBE ARE NOT TYPICAL OF EXCESS LEVOTHYROXINE. WE DON'T KNOW WHAT HAPPENED EITHER, BUT URGE YOU TO STAY IN TOUCH WITH YOUR DOCTOR.

I would suggest that you speak to your doctor. It is dangerous just taking yourself off medications as some have to be gradually stopped. A blood test is the determining factor. I am a cancer survivor, as well... and something else might be going on. Check with your oncologist. RM

PEOPLE'S PHARMACY RESPONSE: WE DEFINITELY ENDORSE THIS IDEA. IT IS CRUCIAL TO TALK WITH THE DOCTOR BEFORE DISCONTINUING PRESCRIBED MEDICATION.

I had Graves disease that was treated with radioactive iodine 16 years ago. I'm now 56 years old and menopausal. I'm currently taking Levothyroxine .088mg.

The problem I'm having is when my TSH test comes back normal but I still feel bad. My TSH is about to go out of range in about two months and I feel bad. Then the doctor changes my medicine and It takes two or more months before I feel better. Would it help if I could take to different doses to help keep me in the middle range longer? Thank you dlbn

It is important to discuss this problem with your doctor. What does he/she recommend? Perhaps you would benefit from seeing an Endocrinologist who specializes in these problems. Please do not take it upon yourself to adjust your medication. Good luck!

I take Synthroid for hypothyroidism. When I first started taking it (am) I experienced extreme muscle fatigue (I work out 4 - 5 times per week). I recently missed a few days of meds due to being stuck in Atlanta's snow. Once again, on starting back I felt extremely fatigued. Is this a side affect? If so, do you recommend another medication? Thank you

PEOPLE'S PHARMACY RESPONSE: IF THE DOSE IS RIGHT, THIS MEDICINE SHOULD COUNTERACT RATHER THAN CAUSE FATIGUE.

Hi Jennifer, I am not a physician. I think that if you see an Endocrinologist, you will find out what medications and dosages would be best for you.

I usually take a probiotic pearl before I go to bed. Can I take it with thyroid med?

I was under the impression that thyroid meds needed to be taken on an empty stomach (2 hours after eating and nothing for 1 hour after taking it). This would mean that you could not take a probiotic with it.

PEOPLE'S PHARMACY RESPONSE: WE CONCUR.

Jennifer,

You need to be consistent in taking your medication at the same time every day. I take mine at night and in case I'm delayed in getting home, I carrying my medication with me and take it on the road.

I also discovered that by taking the medication at night, there is better absorption. I also got my energy back. I am no longer lazy, lethargic and sleepy during the day. It regulated the circadian rhythm and I can sleep AT NIGHT, and other symptoms disappeared.

I wish the best for you.

Take care.

Hi... I am a 39 yo female and was recently prescribed Synthroid 75mcg after a trip to the ER for heart palpitations and anxiety revealed the following:

TSH (3rd generation): 6.32 uIU/mL
T3 uptake: 29.00 %
T4 total: 8.00 ug/dl

I was under some stress at the time I went to the ER (husband is military and was away at the time and we are in the middle of moving and buying/selling homes) and had NOT been complaining of any hypothyroid symptoms. The ER doctor told me I was having PACs (premature atrial contractions) due to stress, and suggested that I follow up with my regular doctor about the "slightly low thyroid" as he called it.

Now I have read that some of the side effects of Synthroid are heart palpitations, anxiety, insomnia, and vertigo, all of which I am experiencing now. In fact, I'm experiencing PACs again as I type this. It's been about 6 weeks since I started the Synthroid, and within the first few days I felt good, but then felt increasingly poor as time has gone on. I have lowered my dose to half a pill on my own to see if that will help.

My main concern is that perhaps I was medicated without need. I certainly don't see why a person who goes to the ER with heart palpitations should come out with a thyroid hormone that possibly CAUSES them!

The one thing that makes me feel better seems to be Gatorade. I welcome any suggestions and comments! I will be looking for a new doctor in my new home once we get settled.

Sue

PEOPLE'S PHARMACY RESPONSE: WHEN YOU ARE INTERVIEWING YOUR NEW DOCTOR (JUST AS YOU WOULD INTERVIEW AN ACCOUNTANT OR A NEW PROSPECTIVE EMPLOYEE), BE SURE TO ASK HIS/HER OPINION ABOUT HOW TO DEAL WITH THIS. YOUR TSH DEFINITELY FALLS IN THE TREATABLE RANGE, BUT ADJUSTING THE DOSE CAN TAKE TIME AND REQUIRES PATIENT/PHYSICIAN COLLABORATION.

Hi Sue, I am not a physician and those numbers mean nothing to me. It will be a good idea to establish a relationship with a new doctor when you settle into your new home. If I am not mistaken, Gatorade has a great amount of sugar and electrolytes in it, Perhaps the sugar is what is making you feel better or It may be your electrolytes that are out of balance.

I am struggling with my thyroid dose, I am on levoxyl 175 mcg and I feel like it's too much. My Endo would like me to continue on this dose because of my Thyroid Ca. history. If I took it at night would my Doc be able to lower my dose, because more hormone would absorb better? I have major anxiety from this..

PEOPLE'S PHARMACY RESPONSE: YOU COULD DO THE EXPERIMENT. BE SURE TO CONSULT WITH YOUR DOCTOR. LET HIM OR HER KNOW WHY YOU ARE WORRIED.

Hello Amanda, I strongly suggest that you discuss your concerns with your doctors. Perhaps they could consult with one another and come up with a clear plan for you. Work on it as soon as possible because anxiety will not help your situation. Is there a person like a nurse, that could be an advocate for you and get both doctors to come to a conclusion? Best wishes for a speedy resolution to your questions.

I am turning 52 and menopausal. I have been taking Levothroxin 50MCG in the mornings for a couple of years now. Since I am not naturally an early riser but have to get up at 6:30 on the weekdays for work, I tend to sleep in until 9:00 to 11:00 on the weekends. Could this be causing problems such as edema in the lower legs and ankles and hair loss? My energy levels have not been my primary concern.

Rmm, I had several bad symptoms while taking Levothyroxine in the a m. I was told by the physician to take it in the a m then the pharmacist repeated the same so I thought it was written in stone -- IT'S NOT.

A few symptoms disappeared while taking it in the a m. The biggest was no longer feeling weak & lethargic, I was no longer constipated, It seemed that some of my body aches sorta weakened a bit, no longer dizzy, I felt alert because I could sleep, it regulated the circadian rhythm which means I could sleep AT NIGHT & function during the day.

RMM, it can't hurt by trying it out to see what your body experiences. What you experience may be different from me or somebody else.

By taking it at bedtime, your body WILL absorb ALL of the hormone. My TSH went from 4.23 down to 3.15 just by taking it at bedtime.

I am now on my 5th doctor and she did what no other doctor has done -- increased the Levo! 18 of my symptoms have disappeared and I still take it at bedtime. It seems that she is very impressed that I take it at night. She even asked me, "What symptoms disappeared by taking it at night"?

I strongly advise for you to try it to see if you feel any better.

I wish the best for you.
Take care,
Monarch

After taking my first dose of Levothyroxin this morning before eating, it made me very sick all afternoon long with vomiting and diarrhea. I usually can't take medications of any kind without food. What should I do?

I'm sorry that you had that reaction. I think it is important to discuss this reaction with the professional who prescribed it for you. Perhaps there is some adjustment that can be made for you or a different RX might be advisable.

I first wrote in April and have had a few changes to my medication since. I am now taking Armour Thyro 30 MG at night. I stop eating two and a half hours before my pill and I do not eat after. I try to go to bed an hour after I take the pill. I have only been taking this new prescription at night for a month and a half, but I have been feeling so much better.

I have lost eight pounds without really trying. It is most likely cutting out night snacking that has done the trick, but I think my edema is also better - so less water retention has helped with the scale in the morning. What I really like about taking my pill at night is that I can keep a schedule and still have irregular wake up times. (I am a night-owl teacher who is off for the summer.)

I am so pleased that you have found the best way to take your Armour thyroid. From what I can read from other people, what works best is highly individual. Glad you are getting such good results. I wish I could take my 2 thyroids at night but that is the only time I can take my Calcium and that would create a problem. Keep up the good work and not snacking at night will be beneficial if you want to lose weight.


Hello, I started synthroid .75mc 3 months ago and like a previous writer, I felt better at first then began to feel worse. I cut the pill in half until my follow up with doctor at the 3 month mark. Bloodwork revealed tsh still needs to come down (was at at 4.06,now at 3.65) as my endo likes levels around 1 or so.

I have tried to go back to the .75 but about 5 hours after taking I experience heart pounding and mild but constant anxiety. The synthroid has also aggravated my inability to sleep. I take lunesta for sleep issues. I did not take synthroid this morning because I just couldn't bear the thought of wanting to crawl out of my skin all day. I am going to take it tonight last thing before I turn out the light, an hour after my lunesta. I pray this will help.

danna rice. By switching to taking the T4-based medication at bedtime, it will give you a boost in energy in the beginning, just until your body gets used to it.

Later on, you will be able to take it and go right to bed.

It regulates the circadian rhythm by letting you sleep at night and be able to function during the day. I sleep like a rock for 8 hours straight and I no longer wake up tired. It used to take me an hour to get outa bed when I woke up, and since I switched, I feel like getting up when I wake up. It has made such a big difference in my life by just making this small adjustment.

Since the medicaiton is better absorbed, at bedtime, it took away the lethargic feeling throughout my body.

By switching to taking the Levothyroxine at bedtime, I can do what I need to do during the day. I have 17-hour days because I feel so much better.

I hope you find this article to me helpful information to you.

http://thyroid.about.com/od/thyroiddrugstreatments/a/bedtime.htm

My doctor suggested that I take it early in the morning 4 hours before I eat...yikes lol, I am so hungry by the third hour I am awake. Do I really need to take the synthroid and wait that long to eat? and I like this whole bedtime idea. How long do I wait to take it at bedtime after eating dinner?

I take zanac 1mg every night to help me sleep. If i start taking my thyroid med at night will zanac interfere with my medicine?

Danna B. about taking thyroid medication in the Eve--I'm a night person so I eat my meal around 8 p m and I might have a light snack around 9 p m, I take mine anywhere between 10-10:30 p m. An hour is fine, I do that and I feel fine. I either go to bed if I'm sleepy or stay up but I only have water, no food no other beverages. I make sure to get 8 hours without food or beverages.

The medication works like a clock, I wake up in 8 hrs after taking the Armour. I must warn you that it will give you an extra boost of energy for 3 hours BUT only for 2-wks then your body will get into the routine then you will be able to take it and go to sleep immediately, if that's what you need to do. I was diagnosed in 2004 and I made the switch in 2009; I discovered on my own that I feel much better taking it at night or at bedtime when I'm done eating for the day. I hope that you can make the switch.

Linda, The purpose of taking it at night is because then we are basically done eating OR by going to bed then we are not consuming food or beverages AND no more bowels so therefore the medication has a chance to bind to the intestines and receiving FULL absorption. You may find that you may not need the Zantac if you were to receive FULL absorption of the Thyroid medication.

I say that only because I've been told by someone else that she was able to cut down on her antidepressant medication once she started taking they Thyroid medication at night; she never let me know if she completely stopped taking it. So by taking it at night OR bedtime then we are absorbing ALL of the medication for 8 HOURS then when we get up, we're ready to eat and drink. I tried 7 hours but that didn't work for me because I felt weak and lethargic. 8 hours works for me, besides the thyroid medication works like a clock, I wake up in 8 hours--just what we all need anyway.

I was diagnosed in 2004 and made the switch in 2009 so for all of those yrs, I wasn't sleeping. When I made the switch, I began to sleep the WHOLE night--8 hrs. They Circadian Rhythm was regulated once I started taking it at night so for the first time I could sleep. Other symptoms improved also. When I started taking it at night, it kept me up an extra 3 hrs, but it wore off about 2 weeks later and now I can take it and go right to sleep OR stay up if I want.

I started taking the Levothyroxine at bedtime and now I'm on Armour so I take that at night/bedtime too. When I switched to Armour, I felt the new effects kick in, in the morning. I felt my depression lift from one night to the morning. Linda, I hope that you are able to make the switch soon so that you can begin to reap the benefits also.

I have recently (about 4 weeks ago) switched taking my Levothyroxine from a morning to a night time and almost immediately I started feeling much better, the following day I woke up and felt I had the energy to get through my chores, my brain fog lifted, yes I still feel a bit tired but no longer feel exhausted, I feel it's the best thing I have done, though I do understand that it isn't for everyone, I understand that at night time your stomach and bowels slow right down so the medication stays in your system for longer which obviously helps

HI, Val H, Good for you. I'm glad to know that you made the switch and you have good results. You may be sleeping better at night now, but you probably feel lethargic in your bones. It seems like the Circadian Rhythm is regulated once we start absorbing ALL of the hormone, meaning that you're able to sleep at night & function during the day.

Once I switched to Armour the weakness disappeared and I had improved stamina but still not normal. I think that you are lucky that your brain fog lifted while taking Levothyroxine; mine didn't with 75 mcg Levothyroxine nor did the Depression. I'm really glad that you made the switch and feel a lot better. Keep track of the symptoms that disappeared and the ones that linger because you may need Armour to get rid of the other symptoms. Take care.

I had a severe case of hyperthyroidism about 18 years ago. Ended up having RA and was put on synthroid. Recently on levothyroxine, but just started Armour at my request. I am now 67 years old and in the past year have had hair loss, itching, weight gain, muscle aches, etc. Dr. always says it because of aging. I do not believe that. I am perfectly healthy, eat healthy, exercise regularly..etc.

I requested Armour because I think I need a change. We shall see. But I take my meds at 3:00 am. Only because I always have gotten up to go to the bathroom in the middle of the night so I take my thyroid then. I always know when my thyroid meds are out of whack. I know how I feel and when I tell the Dr she just looks at me like I am nuts. I wish more family physicians were educated on thyroid diseases and how to read the numbers. And I wish more drug companies would take into consideration how messed up the thyroid meds are.

If anyone has taken levothyroxine and switched to Armour I would like to know when I will notice a change in the way I feel and how soon? Thank you.

Doctors instructions will tell you that you must take thyroid meds of any kind should be taken first thing in the morning. I was never instructed until recently when I was being evaluated before starting the new female hormone bio-identical therapy. When I told the doctor that I wanted to continue taking the meds at night since that is when I took everything else. He said that I could do what I wanted but the program would not work as it was supposed because it was very important that I take the thyroid first thing in the morning.

Before starting the hormone therapy program, I decided that I would try taking the meds in the morning so at first it was tough remembering since I have taken if for 15 yrs at night. After a couple of weeks of this, I started noticing that I was not losing my hair like I always have. I noticed that I had more energy so this sold it for me. My mom had always told me should took hers in the morning but I was stubborn, however, after being told by a doctor that it was important and he gave me the whole explanation of what it does for the body taking it in the morning.

From now on, I am telling everyone to take it in the morning and waiting at least 30 min to eat. I thought this would change my entire schedule and that I would not be able to wait to eat but that is not true at all. Take the meds right after you get up, before getting dressed, doing your hair and the whole routine and you will find that 30 min is about how long it is going to take you to get around to eating, I promise.

Recently, my 40 year old daughter was diagnosed with a thyroid problem and when I told her to wait 30 min but her doctor told her to wait 1 hour. Occasionally, I do wait (but not intentionally) 1 hr before eating and I think I may have noticed difference but I need to try this a little longer to see if it is true. But I am here to tell you that you do need to take the meds in the morning or you will continue to notice weight-gain, hair fall out, nails getting thin, no energy, etc.

I know all the things thyroid does to the body but do not want to list them all here for fear I will leave something out and some are not easy to write about. PLEASE, all who read this, at least try it for a while to see if you notice a difference before ruling it out taking in the morning!!!

Taking Synthroid at night: My new doc said to take Synthroid at night for better absorption. I did as instructed for 3-4 weeks, then I started waking up -- for hours -- in the middle of the night. I have always been a deep sleeper who doesn't wake up before morning, so I realized that the sleeping issue was from the nightly thyroid dosings. I had to switch back to morning dosings so I could sleep fully through the night.

Note: the nightly dose didn't make a significant difference in absorption. I was at 6.2 (TSH) and it only went to 5.8 over six weeks -- still high.

Susie, the body needs to get used to the change. If you take half at night and the other half in the morning just until your body can adapt to the change. After a week or 2 then you can take the whole dose at night.
I really benefit from taking it at night. If I take mine in the a.m. or during the day, I feel like wilted lettuce ALL day.

When I was first diagnosed, the doctor advised me to take the Levothyroxine in the A.M. so I did because it SEEMED like the right thing to do at that time.

While taking it in the a.m., I couldn't sleep, I couldn't function during the day due to body aches & NO sleep. Had a bowel movement maybe once a week; ALL of this disappeared by taking it at bedtime.

I'm now on Armour and still take it at nighttime. I find that the Armour also regulated my bowels better so when I eat fiber during the day it promotes a BM; Levo didn't do this.

I have shared with a hand-full of people to take it at bedtime and it has changed their lives.

I instructed a nurse to take hers at bedtime and she said to me, "There is a science to this. According to my studies, it's the right thing to do and why hasn't my doctor told me about this."

Doctors don't know any better than a NEW PATIENT. A new patient just does what the doctor says because of his BOOK-READ education. ANYONE can read a book or 2!! I've done lots of research and taking it at bedtime gives the medication time FOR US TO ABSORB ALL OF IT. By taking it during the day it gets mixed up with food and beverages and gets thrown in the toilet, which I think that's where mine was going because I could barely function by taking it in the a.m.!

A month ago, I had hemi-thryoidectomy for a toxic nodule and a cyst which turned out to be cancerous. We were hoping that the other half of the thyroid would start functioning but in the last two weeks I have started feeling unwell. It was confirmed I am now hypothryoid and I need to take 50 mcg of Synthroid. I understand it's most important to be consistent with the time I take my pill. I want to learn more about my diet and how it could be impacted. Obviously this is something I have to deal with for the rest of my life. I'm terrified of weight gain and return of cancer on the remaining thyroid tissue, where I already have a cyst. Any suggestions would be appreciated.

Can you tell me if there is a problem taking synthroid along with gabapentin? I would like to switch to the nighttime routine as suggested, but I do take gabapentin at night.
Thanks.

LS, You can also check with your pharmacy. They would know if the Gabapentin would conflict with taking your Synthroid together.

I am currently taking 30 mg of Armour in the morning. I am going to try a nighttime schedule and see how that works. In the morning, I take Armour at 6 AM, then eat an hour later...multivitamins with iron, calcium, fish oil 4 hours later. It seems this either stops the absorption..or too much at one time...
and lately have cases of heartburn...so going to try the Armour tonight and see how it goes for a week...

What do you think? From what I've read, most say the night time dose works best. I am a good sleeper...I sleep better with the Armour esp. in the morning...

Laura

I am going to start on Levothyroxine 25 mcg. Currently I take folic acid after lunch and prenatal before going to bed (not pregnant- hoping to try after balancing thyroid issues). Can I take levo along with prenatal or should I try to shift my prenatal sometime to the morning. Pls suggest.

My thyroid levels are. TSH - 3.69 TOTAL T3 - 1.0 TOTAL T4 -6.5

All of the above seems to be in range. Only out of range component is ANTI TPO AB - 49
Pls help.

People's Pharmacy response: Your prenatal supplement may contain minerals that could reduce levothyroxine absorption. Take them at different times.

Hi!I have been taking synthyroid medicine-75 mcg for the last one year as per my prescription. However recently I have realised that the current synthyroid medicine I have been taking for the last three months is of 175 mcg dosage though as per my prescription it has to be 75mcg.

Am assuming either it is a mistake of the concerned pharmacy or there has been error from the doctor's office.

I am wondering if anybody tell me if there can be any major side effects for the same.

Thanks,
AS

I learned recently that synthroid/levothyroxine should not be taken with iron, antacids or coffee. One of the reasons that the medication may not work in the morning is that most people drink coffee in the morning. Each of the items previously mentioned have a negative effect on the way the body absorbs the medication.

Because I take iron every morning and drink coffee I started taking the synthroid at night. I am not joking when I tell you the results was a very noticeable increase of alertness, energy and decrease in fogginess, fatigue and moodiness.

About a week ago I had received my new bottle of synthroid and left it in the kitchen. Not feeling like getting out of bed that night to retrieve it I decided to wait until the morning to take the synthroid. What a huge mistake... the next morning the old sluggish, moody me was back. I can assure you that from now on the one thing I will always do is make sure synthroid is taken at night.

After taking synthroid for nearly 20 years, what an amazing improvement this one small change has made in my life!

Thank you for this info. I take levothyroxine and thought I would never sleep again but taking it at night has helped a lot, I can sleep and no longer have constipation or a metal taste.

Jenny, that is really great that you learned and experimented the difference in taking thyroid medication at nighttime versus in the a.m. Now, you can enjoy your coffee in the morning. For me, I felt an instant change in the morning when I first took it at nighttime. What a difference! My life improved taking it at night as well as yours, too!

Hey, Amy, that's really great.

I have been on levothyroxine for about 12 years. My doctors haven't been able keep my levels in a normal range. I will be okay for a little while and then my levels drop. When I started taking thyroid meds I was taking 25mcgs. My current dosage is 300mcgs. No that is not a typo it is really 300. I continue to experience fatigue, weight gain, chronic edema, insomnia, muscle aches. The whole spectrum of hypothyroid symptoms.

I had my thyroid removed about 11 years ago because of nodules and thyroid cancer. I haven't felt "normal" since the surgery. I have packed on 100 pounds since the surgery. I have also had a positive ANA test with elevated scleroderma and inflammation. Has anyone had any experiences like mine? Did anything help?

Wow. I'm going to try taking it at night. I am a night owl and sleep late when I can, but even though my TSH is 2.1, I still feel tired almost the whole day. It seems to take most of the day to "wake up" and I'm sluggish and moody too (but I figured that was peri-menopausal stuff anyway). Then at night, I'm awake! I'm starting tonight to take it and will give it a few nights or week to settle in. I would love to finally wake up at a decent hour and not feel so tired. I have a friend who is dividing hers up (she takes something diff. than synthroid) to twice a day and is feeling so much better. I will report back!

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