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One high-profile study of a cholesterol-lowering drug has been especially influential. The study was called JUPITER, which stands for Justification for the Use of Statins in Primary Prevention. The study included more than 17,000 healthy people with normal or low levels of bad LDL cholesterol, but high levels of C-reactive protein, a marker of inflammation. They were given either Crestor or a look-alike placebo, but the trial was stopped early after less than two years. The scientists running the trial reported remarkable results: the risk of cardiovascular complications was nearly half in the people taking Crestor.
Now, an independent international team of researchers has examined the data from the JUPITER trial and concluded that the study was seriously flawed. Their statistical analysis suggests bias in the study's data. Worse, the analysts point out that more than half of the original JUPITER investigators had financial ties to the maker of Crestor and thus had an apparent conflict of interest. The international experts conclude that the results of the JUPITER trial are clinically inconsistent and should not be used to guide medical practice. They call for a critical reappraisal of cholesterol-lowering and statin treatments for the prevention of heart disease complications, with greater emphasis placed on a healthy lifestyle.
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It always seems to come back to diet and exercise. We just don't want to do these things and give up the pleasure of a hot fudge sundae three times a day - everyday!
I was reading a study that showed those who went on several well known healthy diets AND LOST weight and kept it off had the greatest success in lowering lipids and extending their lives. They had to eat a healthy diet and less food.
When I could not take statins anymore because of severe muscle pain I was Rx'd to Zetia. After 3 years the same severe muscle pain returned. I'm now on Trilipix for Trigliceride reduction. Any other cholesterol reductions remedies out there? I'd welcome your suggestions with your results.
Red Rice Yeast does a good job of reducing high cholesterol without as many side effects. You would need to work with your doctor before trying it since you are already using Trilipix. There may be contraindications to using the two together. Good luck!
Look into Niaspan time release niacin.