Q. More than 20 years ago I came across an article promoting l-lysine as a preventive measure against cold sore outbreaks. Having suffered with this virus since adolescence, I was motivated to try the supplement.
In my experience, l-lysine is a miracle drug. I used to have at least one outbreak a month, but I now only feel the initial “tingle” of a cold sore if I have overindulged in caffeine, been under an abnormal amount of stress or spent too much time in the sun. I take 1000 mg a day, every day. If I feel an outbreak coming, I triple the dose for a couple of days and the outbreak is prevented.
A. Many people report, like you, that l-lysine seems helpful in preventing or healing cold sores. Double-blind studies on l-lysine for cold sores have produced mixed results. There has been surprisingly little research in recent years, however. This amino acid appears relatively safe although some people report digestive upset.
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