Q. You recently mentioned the value of l-lysine for dealing with cold sores. I have struggled with cold sores and fever blisters for over 50 years.
About 20 years ago, I first tried l-lysine. I’ve found that taking 1000 mg twice a day at the first sign of a “tingle” stops the cold sore immediately.
If I miss that signal and a blister forms, taking l-lysine makes the blister disappear within a few days: no scabs, no inflammation. My brother has had similar good results with l-lysine.
A. Like you, many people who suffer from recurrent cold sores report that the amino acid l-lysine can be useful in shortening the attack. Despite such testimonials, however, there is a surprising lack of recent clinical trials supporting the use of l-lysine.
Older studies were inconclusive. Without better research it is hard to say whether this natural product is really better than placebo. On the other hand, l-lysine appears safe.