Q. Does Topamax cause complete lack of sexual desire? And I do mean complete!
A. Topamax (topiramate) is prescribed for epilepsy, but it is also used to prevent migraine headaches. Your short question implies a lot of frustration and sent us hunting for an answer.
“Decreased libido” has been reported as a side effect of Topamax in the prescribing information provided for doctors. It seems not to be very common, though, affecting just a few patients in a hundred.
Doctors have also described cases in which Topamax completely blocked women’s ability to achieve orgasm (Neurology, Oct. 25, 2005). About five days after discontinuing the Topamax under medical supervision, the women were once again able to climax.
Never stop an epilepsy drug suddenly without your doctor’s approval. An unexpected seizure could be devastating.