Q. Can Synthroid and ferrous sulfate be taken at the same time of the day?
A. No. Iron supplements such as ferrous sulfate interfere with the absorption of Synthroid (levothyroxine) taken to treat thyroid problems. Wait at least two hours after Synthroid before taking iron, calcium or other minerals.
Coffee, especially espresso, can also interfere with Synthroid absorption. So if you take your Synthroid in the morning, be sure to wait at least half an hour or preferably an hour before having your coffee.
Another option would be to take the Synthroid at bedtime, at least three hours after supper. Research has shown that this too works very well.