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Q. Five years ago I developed duodenal ulcers after taking Fosamax for six weeks. I was also taking ibuprofen for headaches at the same time.
Last year, after taking baby aspirin for a few months, an endoscopy revealed more ulcers. I was diagnosed with H. pylori and treated with antibiotics.
I have bad osteoarthritis pain in my right knee and hip and would love to take ibuprofen instead of Tylenol, but I don't want to take omeprazole long-term and don't want to risk another ulcer.
Since the H. pylori is gone, could I risk the ibuprofen? Or is there some other agent I could take that would relieve the pain without causing ulcers?
A. The combination of Fosamax with the nonsteroidal anti-inflammatory drug (NSAID) ibuprofen was a prescription for trouble. Both medications can cause ulcers. A study of Fosamax together with a different NSAID, naproxen, showed that ulcers were more likely in women taking both medicines (Archives of Internal Medicine, Jan. 8, 2001).
Helicobacter pylori (H. pylori) is a stomach infection that increases the risk of ulcers. Even without H. pylori, you might still be susceptible to ulcers if you take aspirin or an NSAID.
We are sending you our Guides to Digestive Disorders and Alternatives for Arthritis, with information on arthritis drugs that are less likely to cause ulcers as well as non-drug approaches to relieve arthritis pain. Ask your doctor about either Disalcid or Trilisate, anti-inflammatory drugs that are less likely to cause stomach irritation.
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8-15-08
Dear Joe & Terry.
I am taking 150 mg of Zantac for heart burn for the last
month . My question is can long term usage cause any
problems ? I am in the process of withdrawing from
Prilosec 20 mg which I used for the last 8 yrs. !
PEOPLE'S PHARMACY RESPONSE: ZANTAC IS NOT AS STRONG AS PRILOSEC AT SUPPRESSING STOMACH ACID, SO LONG TERM USE IS NOT AS PROBLEMATIC.
I have been taking Ibuprofen for several years as an anti-inflamatory. Occassionally it will upset my stomach and I'll stop taking it for a while - but eventually need to restart.
Is there such as thing as an ibuprophen patch? If so would that cause stomach problems? Also, I suspect there is a supository ibuprophen...is that problematic???
Unfortunately Ibuprophen is the only thing I've found that works for me, and was actually recommended by a specialist I was seeing.
Thank you...
...Bruce
PEOPLE'S PHARMACY RESPONSE: THERE IS NO IBUPROFEN PATCH THAT WE KNOW OF.