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Metoprolol

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Generic Name is metoprolol tartrate (ma TOE proe lol / TAR trayt) and Brand Name is Lopressor (loe PRES sor)

Generic Name for extended release is metoprolol succinate (ma TOE proe lol / SUK sin ate) and Brand Name is Toprol-XL (TOE prawl ‘X’ ‘L’)

Overview

Metoprolol is available as metoprolol tartrate (Lopressor), an immediate release tablet and metoprolol succinate (Toprol-XL), a long acting, extended release tablet. Metoprolol belongs to the group of heart/blood pressure drugs known as beta-blockers. That means they work partly by blunting the action of adrenaline, the body's natural fight-or-flight chemical. People normally respond to stressful situations with a rapid pulse, a pounding heart and an increase in blood pressure. Metoprolol (Lopressor, Toprol-XL) helps block such reactions by slowing the heart rate and relaxing the blood vessels so the heart does not have to pump as hard.

Metoprolol (Lopressor, Toprol-XL) is usually prescribed for high blood pressure, chest pain, heart attacks, and prevention of a second heart attack. The extended release metoprolol (Toprol-XL) is also used in combination with other medications to treat heart failure. Although the FDA has not specifically approved its use for other purposes, doctors sometimes prescribe metoprolol (Lopressor, Toprol-XL) to treat irregular heart rhythms or tremors, and to prevent migraine headaches.

People’s Pharmacy Perspective

Beta blockers have been around a long time and generally have low cost generics available. One word of caution, however: We have heard from a significant number of people that not all generic Toprol XL (metoprolol succinate) is created equal. Some people have seen their blood pressure skyrocket while others have developed irregular heart rhythms. See their stories.

Beta blockers such as metoprolol should probably not be considered as first-line treatments for high blood pressure (1,2). British hypertension experts reserve beta blockers almost as a last resort, when other blood pressure medicines don’t work (3). Since beta blockers have the potential to cause numerous side effects (and negatively impact blood fats), we agree that they should be used cautiously.

Beta blockers are valuable for managing chest pain and preventing another heart attack after someone has already had one. They may also be valuable when adequate blood pressure control is not achieved with other classes of drugs. You and your physician will need to decide if the benefits outweigh the risks.

Be certain to consult a physician about your health, especially with regard to any signs or symptoms that may require diagnosis or medical attention. Information provided is not a substitute for the medical advice or care of a physician or other health care professional.

Special Precautions

DO NOT stop taking metoprolol (Lopressor, Toprol-XL) suddenly without first talking to your doctor. Stopping abruptly may trigger potentially fatal heart problems.

Pregnancy/Breastfeeding: Consult your doctor if you are pregnant or planning a pregnancy, or will be breastfeeding while taking this medication.

Metoprolol (Lopressor, Toprol-XL) is not recommended for some people: People who have had an allergic reaction to beta-blockers, metoprolol (Lopressor, Toprol-XL) or its components and people with certain serious heart problems, such as heart rates less than 45 beats per minute (for heart attack patients) or abnormal heart rhythms. The medication could occasionally lead to serious cardiac complications for these individuals. Note that only metoprolol succinate (Toprol-XL), the extended release tablet, is indicated for heart failure. Metoprolol tartrate (Lopressor) is not recommended for people with heart failure.

Some people must be very carefully monitored if they take beta-blockers such as metoprolol (Lopressor, Toprol-XL). In general, people with heart failure must be extremely cautious if prescribed beta blockers because the medicine could lead to cardiac complications. Those prescribed metoprolol succinate (Toprol-XL) are no exception; other medications they are on may need to be adjusted, and most importantly, they must be closely monitored for worsening of their heart condition.

Asthmatics and patients with other respiratory problems are especially vulnerable, as these drugs can make breathing worse. Metoprolol (Lopressor, Toprol-XL) may be a little better than other beta-blockers in this regard, but monitor your breathing carefully. Diabetics should inform their physicians if being prescribed metoprolol (Lopressor, Toprol-XL) since the medication may mask the signs of low blood sugar levels.

People with a history of depression should inform their doctors to ensure both their depression and beta-blocker therapy is well managed. Metoprolol (Lopressor, Toprol-XL) is more likely to affect the nervous system than others in its class and may contribute to depression. People with a thyroid disorder should also be carefully monitored as metoprolol (Lopressor, Toprol-XL) may mask signs of an overly active thyroid. Lastly, people with liver impairments may also need to be very carefully monitored.

Be certain to inform your doctor of any other conditions you may have. This information may affect your dose, whether you should even take this medication, or require you to take special tests during treatment.

Taking the Medicine

Metoprolol (Lopressor, Toprol-XL) is best absorbed when taken with or right after meals. Food may reduce the risk of digestive tract upset and taking the drug at roughly the same time each day allows your body to maintain a constant level of the medication in your blood stream. Metoprolol (Lopressor, Toprol-XL) should be taken with a full glass of water. Avoid alcohol while on metoprolol (Lopressor, Toprol-XL) because it increases drowsiness and dizziness, and do not take calcium supplements or antacids within two hours of metoprolol because they may reduce absorption.

If surgery is scheduled, ask your surgeon and anesthesiologist to see if your beta blocker dose will need to be adjusted. Never stop taking metoprolol (Lopressor, Toprol-XL) suddenly. Your doctor must reduce your dose gradually to prevent serious heart problems.

Common Side Effects

• anxiety, nervousness

• sleep problems (insomnia)

• tired feeling

• vomiting

• decreased sex drive, impotence, or difficulty having an orgasm

• arthritis

The medicine may also have a negative effect on cholesterol and other blood fats, so a lipid test before treatment and periodically thereafter would be prudent.

Serious Side Effects

Obtain emergency medical care if you experience these signs of a potential allergic reaction:

• breathing difficulties

• swelling in your face, lips, tongue, or throat

Call your doctor promptly if you experience any of these serious side effects:

• feeling light-headed, fainting

• worsening depression, memory loss or mood swings

• wheezing, worsening asthma

• feeling short of breath, even with mild exertion

• extra-slow or uneven heartbeats

• stomach upset, low fever, lack of appetite, dark urine, pale-colored stools, jaundice (yellowing of the skin or eyes)

• swelling of your ankles or feet

• cold feeling in your hands and feet

• hives, itchiness, rash

There may be other side effects not listed here. Talk to your doctor if your condition worsens and ask about any side effect that seems unusual or is especially bothersome. Never stop taking any beta blocker medication abruptly unless you are under very close medical supervision. Angina or a heart attack could occur.

Drug Interactions

• Catapres (clonidine): If you are on both blood pressure medications, do not suddenly discontinue either medicine, as the increase in blood pressure could be life threatening.

• Prazosin (Minipress) is more likely to cause fainting problems when combined with Lopressor.

• Hydralazine (Apresoline), propafenone (Rythmol), quinidine, and calcium channel blockers ([verapamil (Calan)], [diltiazem (Cardiem)]): These are also heart/blood pressure medications, which would have increased effects if given together with metoprolol (Lopressor, Toprol-XL). Taking beta-blockers with calcium channel blockers is generally not advised since the combined effects may lead to serious heart problems. If they must be taken together, the dose of one or both medications may need to be reduced and cardiac function should be carefully monitored.

• Propylthiouracil or methimazole (Tapazole), insulins: Beta-blockers may also make treatment of diabetes and thyroid disorders more complicated. Your physician will need to monitor such conditions closely.

• Antacids containing aluminum or calcium and aspirin, ibuprofen: These can reduce absorption and interfere with the effectiveness of metoprolol (Lopressor, Toprol-XL).

• NSAID arthritis drugs such as ibuprofen, naproxen, and high dose aspirin can reduce the effectiveness of metoprolol.

• Cimetidine (Tagamet) and ranitidine (Zantac): Ulcer drugs may increase the effects of metoprolol (Lopressor, Toprol-XL).

• Barbiturates (phenobarbital) and tuberculosis antibiotics (rifampin): These drugs may reduce the effect of beta-blockers.

There may be other drug interactions not listed here. Do not start any new medications or make changes to your treatment without first consulting your prescribing physician.

References

1. Lindholm, L. H., et al. “Should Beta-Blockers Remain First Choice in the Treatment of Primary Hypertension? A Meta-Analysis.” Lancet 2005; 366:1545-1553.

2. Kaplan, N.M., and Opie, L.H. “Controversies in Hypertension.” Lancet 2006; 367:168-176.

3. Beevers, D.G. “The End of Beta-Blockers for Uncomplicated Hypertension?” Lancet 2005; 366:1510-1512.

Be certain to consult a physician about your health, especially with regard to any signs or symptoms that may require diagnosis or medical attention. Information provided is not a substitute for the medical advice or care of a physician or other health care professional.

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My insurance insists on using generic metoprobol succinate, which does not work as well, causing higher blood pressure, etc... actually ended up in the hospital, with many tests and procedures.

Am I the only one with this problem with generics... and what do you suggest I do?

Thanks
does

Since we used Toprol and its generic made by the same company, and since it has so many cautions and side effects, couldn't it be a matter of proper dosages rather than the quality of the generics?

How do we judge the allowable risks when we use drugs that are useful and have side effects?

If you are taking Toprol and you have symptoms that are not included with the information, please consult with your Dr. IBS is just one of the problems that was a side effect for me for 7 years. Once my husband and I stopped it our problems disappeared. Thanks.

I have been taking Toprol XL in varying doses (currently 50 mg) for 10 or more years, along with a diuretic, Triam/Hctz. (I am 58 yrs. old.) Now my insurance co. is strongly suggesting that I switch to the generic, and has contacted my Dr.'s office. I am reluctant since Toprol has worked well for me. My co-pay is only $11.82 per month. I am also taking Tamoxifen and an 81mg. aspirin daily. How do I decide whether to switch to the generic? Thanks.

Have been on Toprol XL, 50 mg. for 10 years. Insurance co. has required me to switch to generic. I just do not feel as well, with acid reflux, pounding heartbeats and tiredness. I had no problem while on Toprol XL. I also had to switch from Lipitor to a generic but had to try 2 prescriptions before I found one that worked for me.

I am taking lopressor for rapid heart rate and palpitations. When the insurance insisted I take the generic, it didn't work! I have tried the generic 3 times over the past few years... doesn't work. So now I pay full price for lopressor.
Also... in response to my complaints, my cardiologist told me that in a recent study of 4 different medications, Metoprolol was the only drug that was NOT able to prevent sudden death episodes in patients! So... right from the horse's mouth!

Now I am trying Bisoprolol and having good luck!

I have taken Toprol for several years and have recently stopped. I developed very dark urine with a very strong odor and also very low heart rate. What is the cause of the dark urine? It went away within a day or two of stopping the Toprol, but I am concerned about what happened to me.

Thanks,
Brad

Last year my Pharmacy(CVS) gave me a generic (metoprolol succinate) in place of Toprol XL 50mg and my blood pressure went up to the 150 range after a few weeks. I stopped the generic and went back to the brand name Toprol-XL and my BP went down to the 120 range. I showed a clipping from your column in the Chapel Hill newspaper to the Pharmacist but she wasn't aware of the problem. Thank you for publishing it.

I am 35 years old and have high blood pressure and am overweight. I ran out of my bisoprolol on a friday and had no way of filling my prescription as of a sunday night my bp went sky high and went to the ER. My bloodwork and ekg all looked good I had mild chest pains. My doctor happened to be on call in the er and took me off my bisoprolol and told me to start taking 50mg Metoprolol so i took it and went to sleep I woke up with numb lips and left side of my face was numb off n on.

And my bp had went back up again. I called and they wanted me to double up on the dosage to 100 mg Metoprolol tablet a day but to take two of my 50 mg tablets till i could fill my other prescription. so i did this and had the worst day and night i have ever had. Anxiety got so bad i woke up shaking so severe heart racing and dizzyness.

I took my xanex to calm me down and it eased up a bit but I don't think that Metoprolol is for me with those kinds of side effects it has kept me from work for two days. I plan on going back to my bisoprolol since i have only taken 4 of these pills i don't think there is enough in my system to cause anything bad as i intend on starting my bisoprolol asap. Thank you I hope this helps.

I cant remember if I took my metoprolol xl or not tonight, and I'm not sure if i should take a dose and risk double dosing or if i should not take it and risk skipping a dose. It really sucks because I know I'm not going to get an answer tonight. I guess I am just going to skip it. It is most likely the safest bet. But could someone give me some insight if this is to happen again. Thank you.

I suggest that you buy one of those strips at Wal-Mart (or another store), with one small container for each day of the week. Insert your pill(s) and take them out of the container so you can later look back to see if you have taken it. Then you will never be worried about it again!

In November I went for a refill on my 25mg metroprolol succinate ER, which I've used for 4 years without incident. It turns out the distributor, Santos, had recalled the product, and I ended up with another generic. 4 days later the problems started: palpitations, chest tightness, higher heart rate, cold hands and feet, higher blood pressure, slightly swollen and throbbing throat, and mild depression.

My doctor said that the brand name is always better anyway, and put me on Toprol XL: but the problems remained. If the generic sucinate ER wasn't causing problems and the brand name is, what does that tell me? Toprol XL just doesn't seem to suit me, whereas the succinate ER did. Does anyone have any insights? Where can I get the succinate again? Or is there an alternative I can discuss with my doctor? It's not in my head. I'm a pretty rational person, and this is all wrong. I understand that many people are saying the brand name is better, but in my particular case, the opposite may be the case.

I was put on metoprolol because I attempted to get off Klonopin too fast which I learned the hard way. I ended up in ER with a heart rate of 149bpm. I had no idea that you had to get off benzo meds verrrrry slowly. I did not go cold turkey-but I also did not do it in a very slow fashion. I was given Metoprolol extended release- 100 mg a day to help get the high rate under control. Well, I did get down from the 149 bpm. But the problem is, I have always had episodic sinus tachycardia and this drug has been THE WORSE AT HELPING TACHYCARDIA !

I used generic Nadolol in the past- on a as needed basis in baby doses and got far better results for my episodes. Now I am weaning myself off this useless Metoprolol and am down to 50 mg and I feel like I did when I first took it- like I am on a sugar pill. It just does not work for me.

Yet Nadolol is a generic and it did help me and I did not need it on a daily basis either. My goal is to get off the Metoprolol completely, but a part of me almost feels like it is actually MAKING MY TACHYCARDIA WORSE. Not only is my rate faster than normal( but no where near 149bpm) the level of pounding to the palpitations is annoying at best- down right scary at worst.

I would not recommend this generic drug to anyone. One other thing: I was finally off anti-depressants when I got put on Metoprolol. DEFINITELY CAUSED DEPRESSION & ANXIETY. Think twice before you go with generic on any drug. I have always heard beta blockers are one line of medicine you should always try to buy in brand formula.
Metoprolol has been horrible for me and I have been on it since Oct 2008 :(

I have too been taking Metoprolol tartrate 50 mg 2 x daily for a couple of years, for rapid heart and palpatations and a slight arrthymia( sorry if its not spelled right ) At first I was only on 25 mg 2x a day but my rapid pulse still remained, so my doctor raised my dose to 50. At first it helped alot. But this is 3 years later and I'm having all kinds of problems.

My heart is racing again, sometimes over 160 bpm, I have spikes in my blood pressure from sitting (147/100) to standing (119/78). I also have unexplained diarrhea for 6 months straight. I have terribly anxiety and am having to see a doctor for that too. Can Metoprolol tartrate cause the diarrhea?

I've have every test you can think of done to me and they all come back normal. I need any and all info on this. Like I said I've been going through this for 6 months having to take Lorzepam 1 mg 3x a day which before my Metoprolol was raised I only took 1 mg of Lorazepam a day, I'm afraid to eat because it make my rapid heart rate faster and it starts when I get up every morning.

Taking it kinda calms it down but it always gets right back up there somehow. The diarrhea started first then all this other, can it cause the diarrhea? If so what is the best to take for rapid heart rate and arrhythmia? I've also been on Atenolol 25 mg with no stomach problems and less anxiety but it completely quit working for me. Any advice will be appreciated. Thank you so much. Also I am 28 years old and also overweight. Have had this problem for 8 years. Thanks again.

I have a question on metoprolol tartrate. I was put on metoprolol sussinate ER 12 1/2 mg per day Oct.2008. Just got switched over to metoprolol tartrate 12 1/2 mg per day. I am currently on lorazapam 1 mg per day. Both very low mg per day. I am in the process of weaning off the metoprolol tartrate 12 1/2 mg because of to many side effects..yucky!! My doctor has me taking 4 more days of 12 1/2 mgs and then cut that in half for about 5 days and then stop. My question is...Should I have a problem after I stop where my dose is so low? I am thinking not because I also have the lorazapam. Any helpful hints or suggestions? I am only doing this under doctors supervision.

I have been on metoprolo for 2 years and have lost a lot of my hair and have had dizzy spells and over all weakness in arms and legs. I did notice changes in my pill sizes. I recently researched and found out about the recalls. I wish I had been informed about this recall and the problems with the dosage''s of this pill before I lost my hair and felt this way.

It also made my B/P rise! I recently went off of it and my blood pressure went back to normal, and I'm trying to get it out of my system. I have experienced insomnia and weakness in my body and heart palpitations! It has been a nightmare for me that I'm still trying to wake up from..

I'm on Nioxin for my hair now that it is gone. I do have before and after pictures that I showed the doctor, I am now trying to figure out what I can take for heart flutters from M.V.P.

To all of you! Keep on top of the recalls and what the patients are going through and pretty much you will find yourself among them and it's not just you alone. I wish the Doctors would take these complaints more seriously and the F.D A. I do feel it is time for the patients to be heard.We need a web page with our stories with our names, for legal advice for all who have been affected by this drug and hold those responsible for not informing patients of the recall and allowing us to suffer by taking this drug.

Can you tell me if it is OK to eat grapefruit while taking Metoprolol Tartrate 50 MG/ I can not find any information to tell me not to eat it but friends tell me I should not be eating it.
Thanks.

Can you tell me if it is OK to eat grapefruit while on the medication Toprol XL 100 mg?

PEOPLE'S PHARMACY RESPONSE: WE ARE NOT AWARE OF AN INTERACTION BETWEEN GRAPEFRUIT AND METOPROLOL.

I have taken Toprol XL 50 mg for more than 3 years. The pharmacy switched me to a generic. No problem until they switched suppliers. The pill was very large and after a a few days I began to feel awful and my blood sugar was testing quite high. I switched back to Toprol XL and the problem went away. No more generic Toprol for me--ever.

I have been taking 25 mg Metoprolol Tartrate (MT) daily for several years. I'm a member of an Health Maintenance Organization (HMO) and they occasionally switch pills or suppliers. I believe the original Metoprolol given to me was a white, round, and flat 50 mg pill which I had to split in half. It was later switched to a larger red 50 mg pill and then to a 25 mg small white pill. The first two pills seem to work find although I did develop some severe PVC's while using the red pill. However, the small white 25 mg pill caused me to have major breathing problems and I ended up in the emergency room. At the time I did not realize the medication was causing the problem. All sorts of tests were performed on me while I was in the emerency room but no problems were found. When I informed my doctor about this he indicated that all Metoprolol was the same and there was only one supplier. I have not taken anymore of the Metoprolol that I believed caused the breathing problems and have not had the breathing problems that sent me to the emergency room since. Luckily, I still had some of my original Metoprolol and I have resumed taking it.

After 14 years of Metoprolol Succ 10/25mg once a day the insurance company switched me to Metoprolol TAR(L) 25mg twice a day, because of the recall on the Succ. I have taken TAR for about 40 days. In the last few days I have been lethargic at best along with numerous aches (chest, leg, arm) headaches, extreme fatigue and some shortness of breath.

A visit to my doctor two days ago found nothing in an EKG or blood work. Dr. advised to cut TAR dosage in half for 4 days, then half again the next 4 and then none. After reading several post and not feeling any better after 2 days of reduced dosage, should I have concern over the Dr's suggested trial and error method?

He advised if it didn't work he would try to locate a supplier for Succ. I am to monitor blood pressure during this trial and advise him if it rises over 160/95 consistently. I am also taking amlod/benazp 10-20mg once a day and 325mg of ecotrin. Should I seek a second opinion?

since taking Metoprolol Tartrate 12.5 mgm B.I.D. for elevated B/P.. I've experienced shortness of breath, and over-all joint and muscle aches..I'm weaning off..

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I have been on Metoprolol 25mg 2Xdaily for approx. 4 years now since being diagnosed with an aortic aneurysm. I have lost a lot of my hair and I am SICK about it. This was never listed as a side effect that I got from the pharmacy but after doing my research I now see it is a side effect. What is in this drug that causes the hair loss? You would think the pharmaceutical co. could figure this out?? Please can someone help me? Is there another beta that I can take that does not cause HAIR LOSS? I am so worried about this I cannot sleep.

Since my doctor switched me to Metoprolol 100mg twice a day I have rashes in my ears and nose, also my legs and feet swell so bad they feel like they are going to burst.

I've been taking extended release metoprolol, 50mg, for several months, with generally good results. Twice, however, I have woken up with rapid heart rate, etc. Both times this has been after drinking beer the night before. Is this a common reaction? Are there any BP meds that are more tolerant of beer? I don't drink a ton, but do enjoy beers once a week or so. Any suggestions??? I also take Lisonopril in the am. Never had any side affects with that, but I'm at my max dose of that.

Thanks for your suggestions.

I started taking 50 mg daily of Toprol XL in late 2000 after a second episode of atrial fibrillation. (The first episode was resolved with cardioversion.) I switched to the generic (metprolol succinate) a few years ago. I guess I'm lucky but I've never had any adverse effects from either. When I first started with the Toprol XL, I seemed a little more tired than usual so I switched from taking it first thing in the morning to taking it right before bedtime.

Ummm...there is definitely an interaction between Grapefruit and metoprolol (lopressor). In fact, there are over fifty medications, which you should not take with grapefruit. The juice causes the body to ineffectively breakdown the medication, causing toxicity... aka... dangerously high levels of medication accumulation in your body.

Toxicity is very dangerous to the kidneys and can lead to renal failure. I highly recommend discussing this matter further with your doctor. I am a registered nurse, and we provide this information to people all the time. P.S. You may also want to google it and not base your decision to mix the two, based on just one internet site. Hope this information helps

PEOPLE'S PHARMACY RESPONSE: IT CERTAINLY MAKES SENSE TO DISCUSS THIS ISSUE WITH YOUR DOCTOR. WE HAVE BEEN UNABLE TO DOCUMENT AN INTERACTION BETWEEN METOPROLOL AND GRAPEFRUIT.

Lisa, my sister has lost over half of her hair while on metoprolol. Did your hair regrow after getting off the metoprolol?

I am also on Metoprolol E.R. and I have constant blood shot eyes and redness of inner eyelids.Dr. has ordered Prednisone eye drops but it hasn't helped at all. I feel it is caused from the metoprolol. Has anyone had problems with their eyes?

Christine, just to share with you, my sister lost over half of her hair while on metoprolol ER. It is a terrible worry to her. She told her Dr. but Dr. didn't change her medicine. She doesn't know what to do either.

Was placed on Metoprolol ER 50mg once daily. This is the worst medication I have ever been on. I suffered muscle and joint pain so severe it sent me to the Emergency Room, couple that with the other symptoms that cropped up like gastritis, constipation/diarrhea, sleeplessness, drowsiness, dizziness, and overall run down feeling which leads a normally active female directly into a depression. I am weaning off of this and all hbp meds. I will eat right and exercise.

Yes, I have the same issues with my eyes. Red, swollen, puffy, and skin around them is sensitive. I called my cardio doc and he does not believe it is the drug (go figure, it must be in my head!). I am convinced it is a reaction to the drug. I have been on antibiotic eye drops, but it doesn't help. I also have skin problems on my face recently. Saw a dermatologist without any long-lasting results. Frustrated with doctors!

After two years on metoprolol I developed Achalacia which because of its symptoms caused my doctor to recommend a cardiologist who advised my doctor to switch me to omlodipine, resulting in much better control of blood pressure and achalacia (GERD) symptoms.

Results of cardio testing indicated no outstanding heart problems for a 70 year old like myself.

Mike,
I know this reply is a couple of years too late, but someone else may surf by as I did...
Everything I ever see about missed doses indicates you should not double dose. Rather wait and take your next scheduled dose on time. This information should be somewhere in the micetype provided by the manufacturer.

All in all you would probably be safer asking the prescribing physician for advice of this type and not trust anonymous internet contributors. Despite the good intentions many have, their advice could be wrong or just not appropriate for your particular circumstances. And don't ever forget, not everybody does have good intentions.

I have been on lopressor (metroprolol artrate 50mg) 1 twice a day, since 1970 for a clicking heart valve. I suffer from fatigue, cold hands and feet, cold sweats at night and swollen ankles and feet. My Dr. is reluctant to take me off. Do you have any suggestions?

I have been taking Norvasc, and have to take the brand name as the generic causes a fungus to break out on me.The brand works well. I also take Toprol XL 50 mg in generics and I have noticed my hair is thinning. I am thinking of discontinuing it. I also have Gerd. Maybe the Gerd would stop if I don't take the Toprol. I just have borderline BP problems.

I am worried about my hair and hate it being thinner. I am 73 years old and have always had thick hair.

I'm 26 years old I been taking Metoprolol Er Succinate 25 mg(1/2 tablet) for the last five days for my BP. However I've been experiencing pounding in my chest, pains in my lungs also, with high resting pulse. I decided to stop the meds so I missed a dose because I've been needing my asthma meds very often. Will this affect me if I suddenly stop taking the meds?

I have been on Metoprolol ER 50mg 1x daily for 5 months now. I can only relate my experience. I am VERY happy with this drug. Not only is my BP lower but it had an entirely unexpected (to me) side effect. My anxiety is gone. Not totally, but on a scale from 1 - 100 I went from a 90 to maybe 20. I have read that beta blockers can effect some people this way. But I tell you it really has changed my life. No waking up shaking, no heart pounding, no thinking I am dying every few days or so.

I thank GOD for this. I was surprised to see that many were effected in the opposite direction. It must be related to each individual. My one complaint is that I have a bad stomach and I believe this pill has made it worse. (Also on Warfarin 7.5 and Multaq 400mg 2x daily)

But I tell you even besides the bp thing, I haven't felt this anxiety free since I was maybe 15. (I am in my 40's) I will stay on this pill for as long as it takes with no complaints whatsoever. (The really bad upset stomach is a fine trade off by me.)

I have severe muscle and joint pains especially knee, foot, back ache, neck pain and leg cramps. Sometimes have problems walking properly. I am on metroprolol 100mg twice a day . I was wondering if you had all these symptoms being on metroprol, just trying to figure out if its the metroprol causing these issues

I have been taking Metoprolol for almost a month and my blood pressure is already much lower, and I feel more relaxed. I also have taken Synthroid for hypothyroidism for 8 years. Since beginning the Metopropol, I do feel a bit lazier and have gained a few pounds, I have occasional diarrhea and dark urine, but the most annoying side effect is that the skin on my neck (and only my neck) is frequently itchy. This drug seems to have a highly personalized reaction to each user. Overall so far, the benefits outweigh the drawbacks, for me.

I had a heart attack on 6/2/10 and now am on two drugs----Lisinopril and Metoprolol ER----Recently, I have noticed terrible muscle pain/cramps and have to take a lot of NSAIDs (Ibuprofen)in addition to the Aspirin that I take every day. I see, on more than one website that both Lisinopril and Metoprolol can cause muscle pain---one was listed as a cause of Arthritis!!! This muscle pain is a lot more than an occasional "twinge" of discomfort---what do Cardiac patients do????? Risk another MI from high blood pressure and its complications or suffer through what I've been going through this past week?

Ever since my Dr changed my medication to Metoprolol ER I have had BAD lower back pain. Just a coincidence?? I don't know. I am currently in physical therapy for the pain. It helps but has not gone away and I have been suffering for the past 3 months! Had an x-ray which showed nothing. Next step will be an MRI. I have a husband with chronic back pain for many years. With his, the pain comes and goes. But with me, it is constant. And for no good apparent reason. I have this sinking feeling that it is the medicine, which stinks because after several years of finding one that works for my HBP, this one works. But I cannot live my life with this constant back pain. DOES THIS MEDICATION CAUSE BACK PAIN?? Or is this a coincidence???

PEOPLE'S PHARMACY RESPONSE: METOPROLOL CAN CAUSE MUSCULOSKELETAL PAIN. PLEASE TALK THIS OVER WITH YOUR DOCTOR.

I had been taking 50 mg Atenolol for many years to control tachycardia and panic attacks. I also always have had mild PVCs (skipping heartbeat)that became REALLY bad after I had severe food poisoning and became dehydrated. That sent me to the cardiologist who thought maybe the Atenolol was no longer working and prescribed 50 mg metoprolol, and he said to try 75 or 100 mg if 50 mg doesn't work. That was 6 months ago and I have just been to hell and back while on the metoprolol. Had worse palpitations than ever before (bigeminy PVCs for days on end where the heart skips every other beat, felt dizzy, panic attacks and anxiety, racing heartbeat, and higher blood pressure than ever before.)

I finally started a log of my symptoms and related them to when I took the metoprolol. The more I took the worse I felt and the longer since I had taken a pill, the better I felt. Then I found info on the Internet that there were a lot of quality problems with the generic version (Metoprolol) of Topril XL. i.e. So today I called the cardiologist's office and asked them to call the pharmacy with an Atenolol prescription.

I convinced the medical assistant that I believed the metoprolol was actually causing my irregular heart rhythms. So I picked up the Atenolol at the drug store and took 50 mg in the car. Three hours later my bigeminy is gone for the first time in 10 days, no anxiety, I feel better than I can remember in many months. I flushed the metoprolol down the toilet!

I've been on Lopressor for a few years, along with 2 other blood pressure meds. I take 100mg lopressor twice daily. Now my heart rate is 46. I am in my 50's. My practitioner found this error & said, she thinks I shouldn't be on Lopressor at all with this low heart rate!! Why didn't my regular Dr. see this???

My practitioner wants to take me completely off of this but I think I should wean off of it! Here I am 2 days later still waiting for their call!!! I am totally concerned with this lack of professionalism on my Doctors part. Needless to say I will be looking for a new Dr.!! Should I stop or should I wean??

I too have been having severe back pain since I started metoprolol about 3 weeks ago. So sore, I can't sit.
I will have to get off. I had hair loss with an earlier drug and I see that this is still going on.

Did you find a drug that didn't have these side effects?

AnnS

I started getting severe back pain (when sitting, not standing or lying down) since I have taken this drug. I will have to go off. Did you find a replacement without these side effects? I may have to move to meditation instead.

The back pain pain is sharp like I am being stabbed. Movement doesn't make it worse. I have to hunt around for a better position and it will stop for a while. It is sore to the touch sometimes. This is the second drug I have tried. Linispril caused hair loss.

Ann S.

Although this medication may work very well for many others, a side effect that made it impossible for me to continue taking it was insomnia. Please let your doctor know if any side effects trouble you, and let him or her make suggestion and monitor the alternatives closely.

I had no idea how bad the insomnia could be, and even though it's listed right in the insert, I found it hard to believe it was the medication. I won't list details here, as each person is unique, but I'm doing much better now. I wish I'd mentioned the insomnia sooner to my doctor and hope everyone here has as good a doctor as I do, who can help you make the right choice for you.

I have been on Metoprolol for about 5 weeks, 25mg in the morning and 25mg in the evening which I only take 12.5mg in the evening due to the side effects. It has helped with my heart palps most of the time. My doctor switched me from Lisinopril due to severe anxiety/panic attacks, had heart palps after starting Lisinopril back in June, and several others side affects.

Initially when I started taking Metoprolol I was tired and unmotivated. I went to my doctor several times due to feeling more depressed, I have some insomnia, seems like I have more rashes, and my lips have swelled 3 different times. My doctor did not seem to be concerned, just felt I was fighting my meds and gave me more meds for the anxiety and told me to have some allergy medication ready if my lips swell. I'm going to see an allergist in the morning for the rashes that won't go away. Does anyone know how long it takes for side effects to begin when taking Metoprolol? Should I be concerned about the side effects as my doctor doesn't seem to be concerned. I have noticed my heart rate has slowed to about 48 bpm. I do run 1 1/2 miles every other day and I'm practicing good eating habits.

I want to get off of med completely, but not sure if taking the Lisinopril and Metoprolol has caused some permanent damage such as heart palps. I'm afraid to slowly take myself off cause last time I tried that with the Lisinopril my bp spiked and I ended up in the ER for severe panic/anxiety attacks. I'm a 35 year old male and have been an athlete most of my life and have never experienced anything like I have been experiencing since starting Lisinopril and Metoprolol. Maybe I will get some answers from the allergist. Any feedback would be appreciated!

My insurance company switched me to the generic and my blood pressure went up significantly. My doctor told me that the generic requires 1-1/2 times the dosage that Toprol XL requires. I did not want to have to take a higher dosage and got him to prescribe DAW (draw as written) for the brand name.

I have the same thing, big red lines, eyes are sometimes sore/itchy. Feels like somethings in my eye sometimes. Lubricant drops don't seem to help.

Has anyone experienced weight gain while on metoprolol? I have increased back pain recently, but can't tell if it's the medicine as I have other joint problems wrong with me, but the weight gain is substantial!

Just started taking it in Jan. 11'I have gained about 2 pounds nothing to bad. I think it cause your joints to hurt sometimes also my finger tips and toes feel sore sometimes, colder hands and feet. This is all new to me just trying to make the best out of it. will start to change my eating and exercise habits to help. I think the problem with a lot of us is to much stress speaking as a 39 year old (female). Good luck to all that's on any form of meds. Have help with my heart rate just have to work my way through side effects, afraid to try something else.

I am taking the medication for a rapid heart rate. It seems to have lowered my blood pressure (although my blood pressure was not high) and I feel better, yet the heart rate is still 95-109 at rest. Can't afford to go back to the doc, so I guess it will do for now, not sure any other drug would work better for the heart rate, with my asthma problems.

PEOPLE'S PHARMACY RESPONSE: BE SURE TO DISCUSS THE ASTHMA WITH YOUR DOCTOR AT YOUR NEXT VISIT; METOPROLOL CAN SOMETIMES MAKE IT WORSE.

I had high blood pressure due to losing mobility (bad knee) and eating too much. My doc tried to get me on metropolo. I read the literature and refused. When it came time for total knee replacement surgery the surgeon blackmailed me into taking it.. The side effects have been ugly.

I had my first collision in 30+ years because I would lose contact with the world around me and not see things (like a truck) Doc said "this is a good one because it has few side effects". BS! surgery will be over soon and I am getting off this crap. I'd rather die than have to stop living so some sob can say he cured a condition that normally needs no meds but exercise and diet control.

Can Metoprolol Succinate ER 25mg BID cause a severe rash (urticaria)?

PEOPLE'S PHARMACY RESPONSE: IT CAN CAUSE A RASH.

I have been on metoprolol tartrate for almost 2mths. The cardiologist put me on this due to high diastolic pressure. For about a month my stomach has swollen, some days I look like I'm about 6mths pregnant. In the last week and a half I have started having terrible stomach pains, in the last few days it has moved to include my spine and lower back. I went to the emergency room a few days ago due to the intense pain, they found nothing. I am wondering if my symptoms are due to the metoprolol tartrate. I am also completely exhausted and have no energy to do anything. Any help would be greatly appreciated.

PEOPLE'S PHARMACY RESPONSE: MUSCLE PAIN, JOINT PAIN AND DIGESTIVE DISTURBANCES COULD BE SIDE EFFECTS OF THE METOPROLOL. FATIGUE IS A COMMON REACTION. BE SURE TO CHECK WITH YOUR DOCTOR ABOUT HOW TO HANDLE THIS.

I have been on Toprol for about 2 years. My calves and eventually the muscles in my butt-ex have been slowly getting sore and painful, as if I had just run a mile or two. Even to the point of being uncomfortable to sit on one position for any length of time. What little hair I had (as a 66 yr old male) is all going away so I just shaved myself bald. After having read all the previous comments, I just put two and two together. I am taking my self off Toprol immediately. I have decided that the benefits of almost all drugs are way overblown, while playing down the awful side effects.

Yes, I do

Thank God For you guys. I have shortness of breathe and difficulty breathing SINCE taking this beta blocker. I going back to the C-blocker.

I am a 47 female and have been on metoprolol for almost 2 years now. I told the doctor I didn't want to be on it any longer (less stress in my life now) so he said that it was OK for me to quit and I asked him do I have to ween myself from it and he said no. I am having nausea and feeling light headed has anyone else experienced this by quitting to medicine without weening yourself from it?

PEOPLE'S PHARMACY RESPONSE: METOPROLOL IS A BETA BLOCKER. WE RECOMMEND NOT STOPPING BETA BLOCKERS SUDDENLY. YOUR QUESTION WAS GOOD AND DESERVED A BETTER ANSWER FROM YOUR PHYSICIAN.

I have been on Metoprolol Tartrate for about a year and a half. I have had no adverse effects from it, outside of some tiredness. I take 25mg twice a day. The one thing I don't like is that I feel it when I come down from it. I can feel my heart beating a bit harder. My doctor gave it to me to block adrenaline from getting to my heart. I have massive anxiety issues, and when I used to get them, my pulse would go up, and scare me, and the attack would last days. I have been much better since on this medicine. I take it in conjunction with Lisinopril HCTZ. My pressure is usually fine.

I am having back muscle pains between my shoulders and I am taking Lisinopril/hctz 10./12.5 and aspirin 81 mg together in the morning for high blood pressure and a blood thinner. Are these medications compatible and can they increase muscle tension?
Leslie

I have been on Toprol for about 2 years. My calves and eventually the muscles in my buttocks have been slowly getting sore and painful, as if I had just run a mile or two.

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I am a 40 year old female who was on Metoprolol ER 100mg for 17 years with no issues. 8 months ago I switched to Lopressor immediate release 50mg twice daily... I found myself exhausted daily, thinking my age was catching up to me I tried to ignore it. One night at work I had to leave to go to the ER with dizziness and chest pain.... turns out my heart rate was 32bpm....... they cut my dose in half and let me go... since then it has been a nightmare.

I am so dizzy and weak I cannot function. I have had four medication changes and am back on 100mg extended release and still not feeling better. This is awful... I feel like I am just dying on my couch. So dizzy and weak I cannot work or shop or do anything. I only feel ok when laying down. Any ideas?

Hi Jay
Don't feel alone; I am a 63 year old male and after hospital treatment for atrial flutter, I was put on 50mg Tartrate (twice daily); this was back in February. After 5 weeks of feeling fine, I started back to work. Two days later, I was mowing a customers lawn, when BANG; stomach pain, bloating, distention (yes, a pregnant male) breathlessness. Your symptoms exactly. Went to my GP four times in 4 weeks trying all manner of drugs for stomach upset. Am now at the point where blood test results came back as all o.k. This has resulted in IBS being thought as the cause; well, the symptoms have literally stopped my life and the pain has been terrible. I have often thought that it could be Tartrate side effects, and having seen all the experiences on this web site, I am convinced Tartrate is the cause. I will be visiting my GP and asking if some other treatment can be tried.

SusieQ, I know this is an old post, but if you see this. Yes! This medication is doing the same thing to my eyes! My eyes always look red and they are dry and burning. I wear contacts. My contacts are monthlies and I can wear them day and night for a month straight and now-a-days I'm lucky if I can wear them a couple of days because my eyes burn so much they just want to fall out. I've also noticed puffiness and redness around the lids of the eyes too. I have no many bad symptoms with these pills. I want them out of my system but I am also scared what the next pill will do to me. If you read this and you were put on a new pill, please let me know what and how it is going??? Thanks!

I'm crying right now reading your post. This is how I feel everyday and I have 3 young children. I'm dizzy, lightheaded, shortness of breath, I feel like I'm faded in and out of reality. It increases my anxiety, and I get scared which kicks in my heart palpitations. I feel sick to my stomach, I feel "hot" but no fever. Sweaty feet & shaky hands. I have migraine headaches daily. Red, sore, itchy, dry eyes. Pain in the back of the eyes. The list goes on.

I have been on metropolol for about 4 months now after a SVT attack where my heart rate was 240 BPM. I didn't realize that this medication was doing this to me. I thought I had some sort of new condition. All I can do most of the time is lay on the couch or in bed and this is not me. I am an upbeat... always moving kind of a person. I can't go anywhere because I don't want to be dizzy in the store and everyone thinks I'm turning agoraphobic... I'm not...I really feel SICK EVERYDAY.

Your hr is too low and wait to take the medication until hr is 70 and monitor severe dizziness is severe side effect call your Dr right away. Need to lower your dose never stop this medicine suddenly very dangerous can cause heart failure.

Update on reply to Jay;

Can confirm stomach cramping and bloating and breathlessness is due to drug; in my case, dosage is too high and am now titrating downwards to find correct level; - this is being done with approval of doctor. At one point I stopped taking one dose of 25mg and within four hours my BP went up to 145/90 and heart rate from 52 to 67 bpm. Amazingly, my stomach also started to work correctly, and I felt normal for the first time in months.

I hope I can come off it altogether, but will see what doctors recommendation is. Hope this helps and will keep you updated.

My Doc started me on Metropolol Succ Er and the first day I couldn't stop sweating and I was in Cold AC. Vomiting every single night I was taking this stuff, Head Ache, Dizzy, tiredness, mild depression, numbness in my fingers and toes, could not sleep at night, heartburn, and some that I might be forgetting horrible experience with this med. I stopped taking it and felt better in 2 days every problem I was having was gone.

Hi all maybe somebody out there can help me with my problem, 3 months ago I had a triple bypass operation and the doc put me on Metroprolol Tartrate 25mg twice a day, since starting the tablets I have a bad body odor that I have not been able to resolve and its driving me mad, has anybody else experienced a similar experience? thanks.

I have been on Metoprolol ER 50mg twice a day for over a year now. I did not have too many of the side effects at first. Only some fatigue. In the last few months I am experiencing the same side effects as many of you. Tingling and slight numbness in arms, hands and upper torso. Severe dizziness. A flushed feeling. A feeling of just being "out of it". Lots of fatigue. Things culminated last weekend when I fainted while playing in a softball tournament. Very scary. I went to the doctor and he said I was over medicated and cut my dosage in half.

I am still experiencing most of the same symptoms except the severe dizziness. After 24 hrs without the medicine my BP has been averaging 137/85 with a 62 HR. I am going back to my Doc this week and insisting on getting off this stuff. It's bad news. I will try every natural alternative but no more of this stuff for me.

55yrs old Female.

I was diagnosed with Ventricular Tachycardia three weeks ago in hospital and the Cardo specialist put me on Metoprolol Tartrate, 25mg, twice a day.

This medication has made my life miserable.
It has made me feel so exhausted and out of it. I can't concentrate on any task that I try to do. I dread going in to work.
I have gone from a cheerful, active, organized, person to someone I don't recognize anymore.

The side effects are awful, Headaches, bloating, vomiting, skin rash, depression, and to top it all, a weight gain of 9 pounds in 3 weeks!!!! (I look 6 months pregnant.) It has made me desperate to come off this drug.

I decided to try medication as a form of treatment instead of the alternative - a Catheter Ablation, because I have to be awake during the procedure. DESPERATE

Most of you are stating the same symptoms I was having since May of 2011. all this time I thought it was my heart condition. I called my doc and asked if I could stop the Metoprolol and said only for 1 week. Then Go from 50mg to 25mg a week later. I take it at night cause I am sleepy after I take it. I still have head pains, sweating, difficulty breathing, etc. The doc said there are other beta blockers out there. Did anyone change to a different one, if so did it help?

I have only been taking it for three days and found that I have side aches and severe back pain. I decided to take myself off it. Is it ok to go cold turkey after only a couple of days on metoprolol tartrate 25 mg twice a day?

All I need to know is a simple answer to the question --- can I take magnesium with metroprol 25 mg. a day ?

People's Pharmacy response: Yes.

I was on 25 mg once a day and my Dr. said I could have stopped taking it. I decided to cut my dose in half. I still have bad side effects but they are a little less since I cut it in half. Try talking half the dose and call the Dr. tomorrow and ask if you should discontinue.

My recurring problem is with very severe muscle and joint pain which make its hard to walk and work. I have been taking Metoprolol Tartrate for at least 5 years and was switched over to Toprol XL and felt it made no difference and made me fuzzy in the head (no better way to put it). I'm trying to find out if the beta blocker causing this, or is it Lisinprol which I take daily. By the way both meds are generic, these HMOs don't give us much choice.

I got vertigo 5 weeks ago and my blood pressure went sky high compared to the healthy low BP I enjoyed for years. I have been on Metoprolol for nearly a month varying from prescribed 2 half doses 2x a day (total 50 mg) to 2 pills twice a day (100 mg) and now am doing Rx one 50 mg AM and half (25 mg) PM. My BP readings have been good at home and still high at the doctor's office. I want to know how other people have reduced their doses safely and gradually. I work with a good PCP but am not seeing her for over a week. I am debating whether to discontinue the 25 mg on my own at night or do I wait to see the Dr. or go to 12.5 at night? I am worried my BP will be too low and definitely want to get off the medicine completely soon in the right ways as I am also into holistic health alternatives

Yes it is. But it has to be two hours before or after you take MT.

How long does it take for metoprolol to fully take effect and the run down and tired feeling does that go away with continued use I want to start feeling better please respond.

I'm trying to determine the cause of severe leg pain when walking up hill or up stairs. I've been on 50mg x 2 for nearly 10 years. I take it both for blood pressure control (bypass in 2003) and to calm my severe familial tremor. I can walk a thousand miles on flat land, but one flight of stairs leaves me in absolute agony. Anyone else experience this?

Re's

Have been prescribed Metoprolol following episode of a-fib. Have had back pain, dizziness, heart fluttering and extreme anxiety the last three weeks since taking this drug. I had no high blood pressure previous to this episode of A-fib. Not sure if my symptoms are from the lopressor drug or something else is going on which caused the a-fib. I don't see doc til end of week. I am upset to see that the side effects are things I was not warned of. Specifically I was never told not to consume alcohol, was not told not to take it with antacid and was not told it could exacerbate depression or anxiety. Anyone's thoughts on this would be very appreciated. My anxiety level is horrible.

Can Metoprolol cause severe leg pains?

People's Pharmacy response: Metoprolol can cause joint pain as well as muscle aches.

Cristi, I am still on the same pill, Metoprolol Succinate 100mg. My eyes are still red, blood shot and burning, but not as bad as it was initially. Eye Dr. gave me Prednisone eye drops,which help when my eyes are at there worse, but it does not cure the problem. I sometimes use Clear Eyes for dry eyes and redness relief. It relieves the redness for a while. I have just started using Blink Tears Lubricating Eye drops and they my eyes feel better.

My Cardiologist said he didn't want to change the med. I will ask him again ---Maybe he will decrease the dose. Try working closely with your Dr.

I developed serious knee, leg, back pain which also affected my butt and could barely walk and sit for any length of time. I had been on metoprolol for at least 5 years and no problem. Then, the Dr. changed me to the slow release meto XL and these problems arose. Also, I started receiving this med via the generic mail order method which is encouraged by the HMOs.

I think that the generics are the problem. Since I stopped taking metoprolol and replaced it with another beta blocker the pain problems are gone.

Hello Laura,

I was prescribed this 2wks ago 4 sinus tachycardia due 2 lack of sleep & stress. I too have experienced your side effects. But after about 3-4 wks it tapered off. What mg are you taking? I was taking 12.5 twice a day.

Actually I have tapered off of it slowly while closely monitoring bp and heart rate. I didn't see cardiologist when scheduled because was in the midst of switching insurances and cards hadn't arrived. See her next week. I feel 100x better of the meds which was 25mg 2x daily to answer your question. My heart rate and bp are all within normal range.

I've been taking metroprolol succ er 50mg am and PM plus benicar HCT 40/12.5c23 at noon. I've been on the metro for about 10 years and the benicar for approx. 5 years. I've been having bouts of nausea during the day but the worst is as night. About once a month, I wake up around midnight nauseated which progresses to dry heaves and then vomiting for approx. four hours at which time the problem subsides and I fall asleep. This has been going on for 1 1/2 years.

I think it may be the metro coupled with benicar and crestor (for cholesterol) which builds up and then releases. The last time it occurred at 8 PM which was early but it was over in 3 hours and the last that I vomited was the medication that I took at supper. Do you think the combination of meds is bringing on this problem?

I also noticed that I am plagued with muscle cramps-feet, legs, thighs (front and back), back and ribs.

Hi Everyone:

I take the Metoprol Tartrate 100 mg two times a day, and it controls my spiking Blood pressure, and rapid racing heartbeats, but I am gaining weight weekly, have the aches, the extreme fatigue, hair loss and hair thinning, dizziness and lack of sexual drive.

I was put on Metoprolol tartrate because of side effects from Lisinopril, which made me very susceptible to heat and I live in the desert. The Metoprolol is doing okay. I am supposed to take 1 25mg tab in the morning with food and another in the afternoon with food. I do find that I don't sleep as well when I take the afternoon one. Is this common? Also, what are the long term problems with taking metoprolol?

I have been on metoprolol ER succinate 50 mg for 2 mos. Today I visited my ENT physician because of a sinus condition that has been going on for more than a month. He asked if I took a beta blocker and I said I did. He was going to write a letter to my cardiologist to see if he would change my medication. I sent a message to my cardiologist and he said he preferred not to change the medication. I can't find anything about beta blockers causing or mimicking allergies.
Has anyone heard of this? Do you think the cardiologist dismissing this too quickly?

I was prescribed Metoprolol T. 25mg in the morning and again at night. I have fought taking any meds for HBP for the last 5 yrs. This is only day 4 taking this and my BP is still as high as it ever was but my heart rate has dropped some... I am having side effects of dizziness, stomach upset/pain every time I eat, diarrhea, low back pain, anxiety and tight throat feeling when I wake up. I called and am seeing my Dr. this afternoon. This stuff is for the birds.

Hi! I've been taking depakote ER and Toprol daily. Recently had hives that covered 80% of torso, but with steroids has went down to very little. After stopping steroids hives have decreased and increased slightly back and forth over last two weeks, but is still just a very small amount now. I stopped the depakote first to see if it was the culprit. It has been 4 days and it is decreasing overall but still slowly. How many days will it take for the hives to go away if I have taken away the culprit? Thanks!

Did you ever wean yourself off and if so what were your side effects when coming off of them and how long did they last?

I was on 50mg twice a day of the extended release. I was later told by another doc that the extended release was only supposed to be taken once a day. Anyway, I was having some terrible effects from the drug and decided to wean myself off. I cut back to 75 mg the first week then down 25 mg more each of the following weeks until I got totally off it. I have to tell you that it was a real roller coaster ride.

I felt extremely dizzy on many days with rapid heart rate off and on. Lots of anxiety too. After I got completely off it for about 2 weeks all the side effects disappeared. I saw a cardiologist and he thought I was being over medicated all along. After experiencing a few episodes of heart flutter after getting off the drug, I am now back on 12.5 mg per day and feel waaaay better. Hope this helps.

So, I saw my Dr. the same day as my last post 12/9 and by 4pm my BP was 200/104... no big surprise to me... she insisted I take one of my pills right then and wrote me a new script for Lisinopril 40mg once daily... she said to take one as soon as I got home and then again every morning. By the time I drove to the pharmacy and then home... 30 miles... my BP was back up to 200/102 so I took one of the Lisinopril. 2 hrs later my BP was back down to a close to normal (for me) of 146/80.

I felt terrible from the side effects of the drugs for the next 2 days and then Monday I was feeling almost normal again. BUT I have not taken any pills since that last one on Friday night (12/9). I've been keeping close tabs on my BP readings everyday and they are way better than while I was taking the Metoprolol. I found a study from the Veteran's Administration that was published online in March of this year that was VERY enlightening... to read it go to: http://www.ncbi.nlm.nih.gov/pubmed/21404131

Did you ever stop your medication? If so, how did it make you feel?

I took metoprolol first time today can I stop it tomorrow?

People's Pharmacy response: Since your body has not yet adjusted, you would not risk withdrawal symptoms. But you really should be in touch with the prescriber so that the problem for which metoprolol was prescribed can be addressed.

Yes, you can. I took it for 4 days and was told, by my Dr., that I could stop without any problems. She was, of course, puzzled as to how my BP got so high while on that drug... 200+ over 104 HR was still 68... go figure...

I am 25 and have tried atenolol now toperol and bystolic... These drugs have caused my joints, back, flank ache so bad every single day. I do not work out anymore and feel as if I am 90 years old. I have 2 small children and now have problems lifting them. I want to wean off so bad. I also have had blood work, bone scan, cat scans,.. I promise, It is the medicine..

PLEASE PLEASE DOCTORS ! TELL ME WHY lisinopril and metoprolol cause such terrible muscle pain and cramping. I am not able to tolerate this one minute longer/ will have to quit my 2nd try at a BP med. I am an RN and no one including pharmacists can answer this for me. I have asked everyone. Thanks

I have been on Metoprolol SUC XL for 7 years. At first 25 mg once a day, no problems. My doctor increases the dosage to 50mg once a day 3 years ago.

For the past year I have had cold hands & feet along with numbness in one foot (on & off). More recently I have joint & muscle pain. Mostly in my legs, abdomen, and arms. I also have shortness of breath with moderate exertion. After reading the possible side affects I thinking it may be the drug.

I have been on metoprolol 25 mg extended release for a month now due to elevated blood pressure. I am only 29 in a very stressful time of my life and had several high blood pressure readings. My doctor put me on the metoprolol and I have been miserable every day this month. Severe headaches, muscle pain, depression and anxiety, hair loss and dizziness has kept me house bound and made a zombie out of me. Yea my BP is fine now but at what cost??!!

I quit smoking and started excersizing regularly so I will be talking to my doctor about stopping this nightmare. And it seems like many people have had the same effects. This is horrible, I wish I was never put on it. Seems like doctors are so quick to prescribe instead of preventing. Now I'm worried about what this pill has done to me, anyone have any feedback??? It's only been a month and it has been a low dose. Thank you for anything comments!!

I took it for only 4 -5 days and was able to just quit but after a month I would think you should taper off... like take 1/2 for a week or two and then stop. So many HBP meds have a rebound affect that can send you BP over what it was to begin with when you stop or even reduce them. Hopefully, you have at least a wrist cuff at home to check your pressure yourself so you can monitor your own BP and see how taking less is affecting your readings. If you don't GET ONE! FYI: Omron makes some really good ones.

Thank you! I did talk to my doctor and he wants me to taper off this. I will be taking a pill every other day for a week and then stopping. Wish me luck! I do have a BP cuff at home, but find myself obsessively checking it so I have to try my hardest to control that.

55 yr old male-I've been on Metoprolol succ. 12.5 mg /day-not much, I know-for high BP-for one year. I look like I'm pregnant. I've read online Met. can cause rapid weight gain and congestive heart failure- I've gained 25-28 lbs since last year. I can barely breathe. I'm going to see my Dr.this Monday to get me off this stuff.

People's Pharmacy response: It's good you are checking with your doctor. Shortness of breath and so much weight gain might hint at congestive heart failure.
http://www.mayoclinic.com/health/beta-blockers/AN01409

After reading your column this morning about Metoprolol's effects, I have read on your site and elsewhere about the side effects and find that I have at least some of these side effects that I had never associated with this medication.

I have taken this medication for 8-9 years. I have had cold hands and feet for a good number of years. Memory loss has become more and more evident, which I had attributed to old age (77) Swelling of ankles and hands. One red flag that I see on your website is the kidney disease.

I don't know if really low kidney function numbers (on the verge of being in the kidney failure range) would qualify as a red flag, too. Do I have enough symptoms to bring this up with my doctor before my annual appointment in about 6 months?

DOES metopolol or beta blockers in general cause or exacerbate psoriasis?

I have been on Toprol Xl and switched to Metoprolol for about nine years. I take 100 mgs. I have recently decided to come off of the med. I will see my doc in two weeks to start weening off. I hope it goes OK. I decided to take natural meds instead. Looking forward to the day I'm off of this stuff.

I have been on metoprolol 25mg er and now pharmacy changed companies and they give me metoprolol xl 25mg and said its same but has caused my heart rate to be higher and I feel more tension. Has anyone had this trouble?

I have been taking the pink Metoprol for several years. However, they switched me to another generic which is white. Since then I have noticed my blood pressure is going up and I am very lethargic. So much so I just don't even want to get up or do anything because I am so tired.

The bottles used to say which company the pills were from but now they don't. Is it possible this is from the change? I mentioned it to my Doc but he said no, highly unlikely but that is not what I have been reading on line.

Sandy~ I had been on metoprolol for at least 9 years without major issues. Then the HMO encouraged me to start on the mail order cheaper generics. These vendors are not identified and renewals appear to be a different vendor due to different color of tablets. It is important to know that many generic medications come from foreign countries, India, China, etc. We don't know if these meds are safe.

I became very ill when I switched over to the cheaper generics and bp went up. I'm better with a change to a different beta blocker, but feel there was some damage done.

I have been on metoprolol 1/2 tab 12.5 mg for about a month now...about three weeks ago I woke up with severe back pain. Now I have severe leg pain and even laying down ob the bed does not help...I never thought it would be this medicine but I'm definitely getting off of it. I can't even stand up and urinate for a minute without this pain...

Elaine,
Thank you for reply. I have been searching and found out the same info about generics. Funny that suddenly they stopped marking the bottles of who makes what we take, this is probably why. I also have been short of breath and want to get off this white generic. I am copying some of these reports and taking them to my Doc next week.

I wonder why some questions are answered on here and some aren't? Will report back what my Doc says.

Tim - what natural "medications" are you looking at in terms of a replacement for Metoprolol?

I was put on 25 mg Metoprol twice daily while in the hospital without my consent. I've only been on it 3 days and want to get off it right away as it has a negative effect on my asthma. I would rather reduce bp by losing a few pounds (in progress). I'm wondering how long I would have to be cutting it back before I can safely go off it?

People's Pharmacy response: The best approach is to work with your primary care physician to get off it. Your reason--that it exacerbates your asthma--is entirely appropriate.

Recently started taking Norvasc (5 mg) because my blood pressure was rising to 200/104 - pulse rate reduced to 45 - Also taking metropol for about 10 years. Blocked out and had to be taken to ER pulse rate could have been about 30-35 - hospital Drs reduced my Toprol to 100 (I was actually taking 200 mg) and increased Norvasc to 10 mg - my cousin (a nurse) explained to me that the Toprol had stopped working on my BP and was now reducing my pulse rate - now have synpoce (as diagnosed by the hospital).

Trying to get rid of this uncomfortable feeling of seeing the ceiling spinning every time I get up from a lying position. Will this cause problems with my liver and even my heart - wants to ask the Dr to take me off Tropol wish there was natural medicine out there instead of these chemicals which sometimes make you medical condition even worst that you were before taking them.

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My name is Michael, I am 32 years old and an active duty Sergeant in the United States army... I just recently returned home from a long year in Afghanistan... Six months into my deployment I was seen by a medic for high blood pressure... 173/116 and a resting heart rate of 126... I had everything from a EKG to an ultrasound of my heart... The cardiologist I was referred to put me on METOPROLOL TART... I have been taking this medication now for 6 months and have not noticed any side effects... My blood pressure has gone down significantly along with my heart rate...

I was just recently put on PROZAC for my anxiety... I was hoping for something more fast-acting and not an anti-depressant as I am not depressed, just very anxious... The military health providers are very skeptical on using any medications with a high risk of dependency such as XANAX or KLONOPIN and said the PROZAC should help...

Has anyone taking these two medications before? and if so... Were there any negative interactions between them?? Also, has anyone's providers informed them to stay away from any certain activities while taking METOPROLOL?? any help would be great... Thanks

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