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Q. I had a wart surgically removed, but it came back. I then spent a nine-month period seeing a dermatologist and trying many different treatments he recommended. I had finally given up and told him I would not be returning.
Upon hearing this, he suggested I try Tagamet, the heartburn medicine. I began taking generic cimetidine (200 mg per day). The wart went away in less than two weeks and has never returned.
A. This unconventional use of the acid-suppressing drug cimetidine has been known for more than a decade. You may have been exceptionally lucky that your wart responded so well. A recent review of studies of this therapy concluded that “Current data do not support the use of H2-antagonists [cimetidine and ranitidine] for the treatment of common warts” (Annals of Pharmacotherapy, July/Aug. 2007).

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Many years ago, when these drugs had first came out, my husband was taking one of them on a continuing basis. I noticed the life-long warts on his hands had vanished, and they have never come back. It was later I had read somewhere that this drug might have been the cure.
I suddenly began to get flat white warts on my forehead and legs, I've had these for several months. I began having problems with stomach acid a few weeks ago and began taking Tagamet in its regular dose for acid suppression. Within a few days the warts began to get smaller, some of the little ones disappeared altogether. I doubled the dose and now the warts are completely gone. It took about a month for them all to disappear. The Tagamet didn't seem to help a small wart I have on my arm, but it is of a different nature. It certainly worked for the flat white warts. Hope this helps someone. Blessings!
I read the articles about Tagamet but actually purchased Walmart's Equate Acid Reducer. I bought it for heartburn but after using it daily for about a month, a wart that I've had for a couple of years on my finger started getting smaller. It's not completely gone but I'm taking the pills until it is. I had tried everything over the counter previously and none of that worked but the acid reducer did.