Q. I have taken Wellbutrin XL for two years and it has taken care of my depression beautifully. In January my insurance company switched me to the generic called Budeprion XL. I didn’t think twice about it. I just assumed it was as good as Wellbutrin XL.
After a few months thinking I was losing my mind and that Wellbutrin just wasn’t working anymore, it finally dawned on me that I was no longer taking WELLBUTRIN! (I honestly hadn’t even thought about the generic.)
I have been very depressed, crying and irritable with no energy or ambition. While I am not suicidal, it sure doesn’t sound like a bad plan most days. I will stop Budeprion XL immediately even though I will have to pay full price for Wellbutrin XL.
A. More than a dozen people have contacted us regarding experiences strikingly similar to yours. Some of them reported nausea or dizziness as side effects of Budeprion XL; all of them said their symptoms of depression had returned.
We have no scientific evidence that there is a difference between the brand name and the generic. Nevertheless, so many reports convince us that there should be an investigation.
We have arranged with the FDA to analyze any generic pills that readers of The People’s Pharmacy suspect are not equivalent to their branded counterparts. Please describe your experience and send your generic pills with as much information as possible: Name of medication, name of generic drug maker, lot number and date dispensed. (Data may be available from the pharmacy.) Send the parcel to Graedons’ People’s Pharmacy; PO Box 52027; Durham, NC 27717-2027.