a bottle of budeprion xl 300mg

Q. I have taken Wellbutrin XL for two years and it has taken care of my depression beautifully. In January my insurance company switched me to the generic called Budeprion XL. I didn’t think twice about it. I just assumed it was as good as Wellbutrin XL.

After a few months thinking I was losing my mind and that Wellbutrin just wasn’t working anymore, it finally dawned on me that I was no longer taking WELLBUTRIN! (I honestly hadn’t even thought about the generic.)

I have been very depressed, crying and irritable with no energy or ambition. While I am not suicidal, it sure doesn’t sound like a bad plan most days. I will stop Budeprion XL immediately even though I will have to pay full price for Wellbutrin XL.

A. More than a dozen people have contacted us regarding experiences strikingly similar to yours. Some of them reported nausea or dizziness as side effects of Budeprion XL; all of them said their symptoms of depression had returned.

We have no scientific evidence that there is a difference between the brand name and the generic. Nevertheless, so many reports convince us that there should be an investigation.

We have arranged with the FDA to analyze any generic pills that readers of The People’s Pharmacy suspect are not equivalent to their branded counterparts. Please describe your experience and send your generic pills with as much information as possible: Name of medication, name of generic drug maker, lot number and date dispensed. (Data may be available from the pharmacy.) Send the parcel to Graedons’ People’s Pharmacy; PO Box 52027; Durham, NC 27717-2027.

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  1. Beverly Reeves
    pelzer sc

    I have just tried to the generic brand of welbutrin for the second time.. I am so ill I can’t stand my own self I’m not sleeping.. getting mean and depressed.. is it a reaction from taking the generic form? Thx.

    • Christine

      I have just experienced the same problem, even though the generic problem was supposed to be fixed. Within a day or two of starting to re-introduce the generic, I was terribly irritable, crying and feeling like I couldn’t think, running into things. The last time I took the full dose of generic, I was so sick I couldn’t go to work and just lay down feeling like I was going to die.

  2. bonnie

    hair loss: Yes, my hair is falling out like crazy. I’ve been on it a year and I’m wondering if I switch to the name brand Welbutrin if I could avoid this side effect.

  3. Christy
    Warrior al

    Has anyone else got a bitter taste that stays with you while taking bupropion? After I took my first pill the biter tast began. Makes food/drink tast bad.

    • dave

      Christy – This is exactly why I’m searching for generic wellbutrin symptoms…sounds gross but it’s almost like ear wax/metallic. I’m so happy at least I found one person with this. I love wellbutrin…I started using it again 6 months ago but the 300xl was too much to start me on…I was having yawning feelings like I needed to yawn. I had the doctor put me on a 150 but didn’t even notice until yesterday they he put me on the generic version…Holy cow! This explains a lot. I’m glad I’m not nuts…..or….glad I’m not that nuts! lol

  4. R

    Any information on the Bupropion HCL 75mg (TEVA) causing hair loss? I’ve lost half my hair volume in the 7 months I’ve been taking this.

    • R

      Sorry, I meant the Apotex Bupropion

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