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Cymbalta and Coumadin Interaction

Q. My mother was admitted to the hospital a few weeks ago for dehydration, acute bronchitis and pneumonia. During the admission, they checked her blood level of Coumadin and discovered it was about ten times higher than normal.


The doctors in the emergency room were shocked, as were Mom and I! The doctor said that had Mom fallen, she could have bled to death in a couple of minutes. The ambulance would never have arrived in time.


My mother was taking Cymbalta as well as Coumadin. The doctor who prescribed this new antidepressant for my mother didn't know about this interaction. It is NOT listed in the prescribing information. Please warn others of this drug interaction, as it may save someone's life.

A. Taking the wrong combination of medicines can be lethal. Thank you for alerting us to the potential danger of mixing the blood thinner Coumadin (warfarin) with the antidepressant Cymbalta.

 

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About the Author
Joe Graedon is a pharmacologist who has dedicated his career to making drug information understandable to consumers. His best-selling book, The People’s Pharmacy, was published in 1976 and led to a syndicated newspaper column, syndicated public radio show and web site. In 2006, Long Island University awarded him an honorary doctorate as “one of the country's leading drug experts for the consumer.”.
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