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There are so many wart remedies it is hard to know where to start or stop. Castor oil applications are highly recommended by our readers. But one of the few treatments that have actually been tested is taking Tagamet.
This research has been published in numerous dermatological journals. We consider this a "home remedy" because it is a novel use for this popular heartburn medicine.
One study found that more than 80 percent of treated patients had a significant response, though it did take six to eight weeks to see improvement.* The dose was 30 mg/kg/day.
Other studies have not had such success. Flat warts seem to respond better than raised ones.
How Tagamet might work remains elusive, though one theory has it the drug modifies the immune system so the body attacks the virus that causes warts.
- Glass, A. T., and B. A. Solomon. "Cimetidine Therapy for Recalcitrant Warts in Adults." Arch. Dermatol. 1996; 132:680�?682.




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My sisters boy, when he was in high school has a severe problem with planters warts on his foot and the doctor prescribed Tagamet in a a very large dose and it worked wonders for him. I do not know the exact amount but it was very large and the pharmacists questioned her about it.
My dermatologist prescribed me 800mg/day of Tagamet for a plantars wart and it worked! This was about 7 or 8 years ago. However, the last time I went to the Dr he wouldn't write me an Rx for it because he said it wasn't approved for that use or something to that effect.
I WAS FIGHTING PLANTARS WARTS FOR YEARS, TRIED EVERYTHING. FINALLY AGREED TO 800MG OF TAGAMET PER DAY. I'VE BEEN WART FREE FOR OVER TWO YEARS! MY NINE YEAR OLD NOW HAS A FEW, I JUST STARTED HER ON TAGAMET, 300MG A DAY. WART FREE FEET ARE WONDERFUL!!!!!!
Have had a raised ugly wart on the side of my hand for YEARS. Nothing the doctor or derma has prescribed worked. Neither anything in the drugstore, not the freeze stuff or the smelly stuff you put on with a wand. Have sliced it with a razor blade, with a pedicure file, anything for years but nothing worked. Then I found out about this alternative cure last week in a newspaper article. Purchased Tagemet yesterday AM, took a 200 mg tablet right away. Significant difference overnight! That's right, OVERNIGHT! Took another 200mg tablet this morning. (Almost) pain free and significant reduction. Can't wait to see what the next week brings.
My podiatrist had me take this for plantars warts on my foot in high school.
After having them cut, lasered, and frozen this worked. Haven't had them since. Over 12 yrs ago.
I suddenly got a bunch of warts near my fingernails and nothing worked untill Doctor gave me 800mg Tagamet and I took it once a day for 2 months and within a week of taking it they ALL disappeared, it was a miracle!!
I have been taking Cimetidine for about a week and have had AMAZING results!! I have had plantars warts COVERING my heel for about 10 years and nothing else has done anything before. They are already reduced to half in size! It is truly a miracle, I still cannot believe I will have a wart-free future to look forward to!
We finally gave Cimetidine to our 6 yr. old daughter. It's amazing! After months and months of visits to the derm., the warts on the back of her hand are gone. She had up to 40 big and tiny warts, they were starting to spread to her wrist and other hand. We'd treated them with everything! Finally 2 tsp. a day for 8 weeks and they just disappeared.
I have had dozens of unsightly warts on my back for years. I tried Tagamet, two 200 mg tablets per day, and it has worked wonders in just a few weeks.
Although this is a little off-subject, I read with interest all the cures etc people suggest for warts and it brought to mind my personal story. I submit it as a matter of interest so make of it what you will.
When I was a boy of five living in rural England (c1942, evacuated from London), I had a sudden onset of warts covering the backs of both of my hands and fingers. The warts over my knuckles cracked and bled .
Several visits to various doctors did nothing to cure them, and over the months they got so bad and ugly I wouldn't leave the house.
Here's where it gets interesting...
One day, in frustration, my mother was relating my plight to the old lady who ran the village store. This woman had lived in the village for many years and suggested we visit the local "witch" as she has been known to cure such things.
By this time my mother was at her wits end and one evening, in desperation, took me to the witch's cottage.
After looking at my hands, she told my mother to wait a couple of days for the next full moon, give me a freshly laundered handkerchief with which I was to wipe the backs of both my hands.
My mother then was to walk into the woods where, in a communal picnic clearing, there was a well known tree stump with a concave top that held rain water. She was then to rinse the handkerchief in this water, return and have me wipe my hands with it again.
With my mother shaking her head in doubt, We did as the witch suggested and within three days my warts were gone and I haven't had one since!
I remember this as if it were yesterday. Strange.
I just had my first treatment for plantar warts ( 4 of them)
the Dr prescribed 2400mg of tagament a day. I am concerned about a large dose, but hopeful it will work.
Well I had a huge plantar wart on the side of my heel. and my foot doctor had told me to take 9 pills of tagamet for relief. is that even healthy? is it possible to overdose ? i just started taking them today. i need feedback
PEOPLE'S PHARMACY RESPONSE: A PLACEBO-CONTROLLED TRIAL OF CIMETIDINE (TAGAMET) FOR WARTS DID NOT SHOW A BENEFIT, BUT A LOT OF PEOPLE HAVE TOLD US THEY WERE SUCCESSFUL WITH THIS TREATMENT.
A word of caution. I have tried Tagamet on two different occasions and both times ended up with severe diarrhea and gas pain that lasted until I stopped taking the Tagamet. It may work wonders for some, but there are others of us who need to stay away from it.
My 6 1/2 year old son was perscribed Cimetidine (Tagemet) for planter's warts. He has been taking the 300 mg dosage twice a day for 5 weeks. The warts are almost gone.
However, he has complained of headaches and stomach discomfort often. For the past two weeks he has complained of pain in his eyes with sensitivity to light. Three doctor's have not been able to determine a cause for the eye pain.
Today has been especially bad for him. We are discontinuing use of the Cimetidine although the doctor's don't believe it is connected to the eye pain.
Any comments are appreciated.
My son is eight years old and had a plantars wart the size of a large pea, plus several pin head size plantars warts on his foot. The pediatrician prescribed Tagamet liquid. It has been approximately one month and the large wart is gone as well as the smaller ones. I had a similar wart as a child and it was dug out of my foot and left a large scar. So grateful our son does not have to go through that.
My 11 year old son had a planter wart on the side of his toe and took 2t of Cimetidine 2x a day for about 3 months and then the wart turns black and falls off. My 8 year old has one now and is taking 1.5 t 2x a day (amt. determined by weight) and looks like it will help him too. The podiatrist said they have great success with children taking Cimetidine, but not with adults because of their weight.
I've had two large plantar warts on my feet for a few years, and only until I visited the podiatrist did they spread to an entire dozen on one foot. He used the blue light laser treatment on me, figuring immediate physical action would get rid of the buggers. I'm a 17yr old female of 125 pounds. After recently switching doctors, I was just prescribed Cimetidine at 400mg twice a day. Is this dosage appropriate for me?
My daughter had so many warts on her hands (more than a million according to the doctor!) that there was nothing the doctor could do: freezing or burning them off was out of the question due to the huge number of them. He suggested Tagamet, we thought he was a wierdo. Two months later there was a significant decrease in the number of warts, and by the third month her hands were as smooth as a baby's bottom, and she went to her prom with her head held high!!
I am a 23 year old healthy male, weight about 170lbs. I have suffered from plantar warts on both my feet and periungal warts under my fingernails for almost four years. I have tried several costly and unsuccessful treatments to cure them (acid, cryotherapy, duct tape, ect).
About three months ago I started researching alternative treatments online. One of those was tagamet (cimetedine) therapy. I figured it was a long-shot with me, but what do I have to lose? About two months ago I began taking over the counter tagamet tablets (The wal-mart knock off to save money). I was scared to try such a high dose, so I decided to do one 200mg tablet with breakfast and one with dinner (400mg per day, much much less than other people took) Several weeks went by and I noticed no effect at all. I was ready to just give up.
Then a few weeks after that I noticed something: There was a small, patch of healthy skin through the middle of the mosaic patch of warts near my big toe. I though, "hey maybe this is actually working". Then a few weeks later and even more of the plantar warts were disappearing, and the big periungal wart on my right thumb was gone.
To this day (about two months since starting my treatment) most of my warts have disappeared, but a few small ones still persist. I'm confident they will disappear with time. To all the naysayers, this was not just my immune system suddenly taking care of them. Tagamet really works.
I read that it inhibits your immune system's suppressor cells, so your immune system can attack the virus and the warts will die. If your reading this and you've been through hell trying to treat your plantar or periungal warts, give tagamet therapy a try. It will take a little while, but patience is the key. Good luck!
I had warts on the bottom of my foot for five yrs..went back and forth to Dr..and he kept scraping them...five months ago I had surgery. I was in a wheel chair for four weeks, did everything I was supposed to do....three months later the virus came back in full force and is traveling aggressively. I tried carac medication for ten weeks with no improvement. my Dr suggested we try twenty eight hundred mgs. of tagamet. I have lupus and a heart condition and was wondering if this dosage is safe.
I had a gigantic wart on my thumb when I was a teenager- it started tiny and just kept spreading. The dermatologist tried salicylic acid over and over again, and tried to burn it off twice with liquid nitrogen (the worst pain I've ever felt...). Nothing worked, and I had it for 5 years- until my pediatrician prescribed Tagamet. I couldn't believe it; it had been the bane of my existence for so long, and it disappeared in a WEEK. What's more, that was eight years ago, and I have never gotten another wart.
To dh: I am interested in your experience since last September. I, too, have been on a 2400 mg regimen and have started experiencing migraine-like headaches and mild nausea after about a week. This sounds similar to some of the other negative side effects being mentioned on this post.
When I was 14 I had over 30 warts on the bottom of one foot. I was too embarrassed to go see the doctor until my mom noticed one day. By the time he looked at my foot, there were too many to remove by burning or cutting so he prescribed me Tagament as a long shot and told me it probably wouldn't work. On the contrary! Within a month, ALL 30+ warts were gone. Painless and quick, it was a miracle!
When I was 16 I had planters warts covering the bottom of both my feet. Some days were extremely painful, to the point I could barely walk. After freezing and the acid treatments my doctor finally prescribed me Tagamet. He gave me a weeks worth of 800/mg and said when I ran out to use the over the counter stuff.... 8 pills in the morning, 8 pills at night... and they should be gone in 2-3 weeks. Sure enough in 2 weeks the warts turned black and pulled off the bottom of my feet like a scab. I have not had warts since (now 26). I had no apparent side effects from the treatment, and I suffer from IBS. I have recommended it to several people.
I had great success with Tagment and my plantar warts. I am female 24 years old 180lbs. Starting November 2008 I noticed 2 small warts. I went to my doctor and had them froze off. They did not go away and 4 more appeared. I went back and froze them again I was left with 3 after that. I went back again same thing they didn't go away and one was growing! So now I have 3 warts, 2 small and one the size of a dime. I had them frozen off 3-4 more times with no success.
I then tried using duct tape with no success and some homeopathic treatments that did not work. I then was prescribed fluorouracil 5 topical cream (chemothearpy) compunded with 30% acid. After 2 months on that they still had not gone away. My Doctor was about to have to surgically remove them which would basically take off my entire heel because of how big the one was and how close the were together. I told him no and asked if there was anything else I could do.
He told me to try Tagamet 200mg 3 times a day in combination with the chemo stuff. 3 weeks and I am wart free. I noticed a difference the moment I started taking the Tagment it was AMAZING especially after all I had gone through to get rid of them. I do think it helped to use the combination but the Tagament is what really kicked them. I was told to continue taking it for another month to be safe.
OMG !!! My teenage daughter had about 30-40 small warts on her hand. We tried everything from going to a dermatologist to having them frozen off, to cream to over the counter wart remedies. She had these warts for about 2 years and they were just so bothersome, plus her skin is so sensitive to antibacterial to lotions, so using all this stuff just made the pain worse for her.
She had even gotten very self conscious about her hand and would hide it when people would stare. We went to a general MD and she prescribed Tagamet 400 mg twice daily for 3 months and I was very skeptical. I was just wanting relief for my daughter, I felt bad for her being around other young people and having to hide her hand.
After 1 month I could not believe it, there was significant improvement. They are disappearing and now into 2 months they are all gone. Her hand is so beautiful and she is trying to break that habit of hiding her hand. We will continue her medicine for another month. I only wish I would of taken a before and after picture of her hand to show this did indeed worked. Its like a miracle. I hope that if there is anyone suffering from warts to try this. Patience is so well worth it, after suffering for a few years. Good Luck !!!
My 12 year old son is severely disabled and had an extreme case of warts on his hands, which was gradually spreading up his arms and to his face. He had them for about 5 years and his hands were literally encrusted with hundreds of warts on top of warts. We tried every other method of treating them, including freezing them off in strips of about twenty at a time. They always came back.
We tried Tagamet for the second time- this time staying on it a little longer. After about three months the warts started to disappear. It's now about six months since he started the Tagamet and there are only a few small remnants of warts left. I hope to stop the treatment shortly. I am thrilled with the results, considering that the problem was getting worse and worse and it seemed that the warts were starting to establish themselves on his face.
My daughter had about 50 black seed warts on toes and feet. We took her to the foot Dr and he started the freezing process that was very painful. We had used every over the counter item. We went to another foot Dr who told was about tagament. She took 100mg in am and 100mg in pm he then scheduled us an appointment in 3 weeks for check up. Amazzzzzzzzzzzzzing -- all of the warts were gone!!!!!!!! Warts are a virus and some how tagament works!!!!!!!!
WOW!!!!!!!!!
I had plantar warts on the bottom of my feet for close to 5 years. It got to the point where I didn't wear flip flops or anything that showed my feet, which was hard because I'm a surfer, and a skateboarder. I tried everything including tape, freezing them off, and going to the doctor to get a blister treatment to lift them off, but unfortunately nothing worked. Then one day the doctor decided to proscribe me an experimental treatment called tagamet to try and help. I took it for 2 1/2 months and my warts went away. I have to say this treatment is NOT experimental. It really works.