wart on a finger

There are so many wart remedies it is hard to know where to start or stop. Castor oil applications are highly recommended by our readers. But one of the few treatments that have actually been tested is taking Tagamet (cimetidine).

This research has been published in numerous dermatological journals. We consider this a “home remedy” because it is a novel use for this popular heartburn medicine.

One study found that more than 80 percent of treated patients had a significant response, though it did take six to eight weeks to see improvement.* The dose was 30 mg/kg/day. To calculate weight in kg, divide the weight in pounds by 2.2.

Other studies have not had such success. Flat warts seem to respond better than raised ones.

How Tagamet might work remains elusive, though one theory has it the drug alerts the immune system so the body attacks the virus that causes warts.

Although a number of case studies and open label trials have produced quite positive results in children, traditional randomized controlled trials in which patients’ parents do not know whether the child is receiving cimetidine or placebo have been unimpressive.

* Glass, A. T., and B. A. Solomon. “Cimetidine Therapy for Recalcitrant Warts in Adults.” Arch. Dermatol. 1996; 132:680-682.

Fit, K. E., and P. C. Williams, “Use of histamine2-antagonists for the treatment of verruca vulgaris.” Ann. Pharmacother. 2007 Jul; 41(7):1222-1226.

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  1. Chris

    I just want to update my previous post. I started taking Tagamet on January 10th 2015 and today is February 11th. Its been one month a 1 day.

    It is hard for me to ascertain if any progress has taken place from the Tagamet, or lack thereof, as I had laser surgery a few days before I started Tagamet on Jan 10. My foot was a total blistered mess. Unfortunately for me, my foot became infected and I had to be put on a high dosage of antibiotics. The infection has cleared up but some days my foot is still in a lot of pain. It is still red and hasn’t completely healed yet from the laser surgery.

    However, I did have a wart on my right hand which “seems” to be shrinking. I have studied my foot and “for once” the warts that were lasered, haven’t come back right away. This could be from having laser surgery on the foot 3x now, or could be the Tagamet or a combination of both. Not sure yet….

    I have been taking Tagamet 2x per day, not 3. I talked to my Doctor today and he was miffed at me for not taking it 3x per day, so Im going to start doing that tomorrow.

    As far as side effects go, I do get headaches more often and I attributed that to Tagamet being an anti-histamine too. I think it dries me out (800mg 2x a day). I just make sure if I feel a headache coming on that I hydrate and pop 2 Advil right away. I was an IBS sufferer, but noticed I haven’t had 1 flareup since starting taking Tagamet. This makes sense, as it is supposed to reduce stomach acid. So, added bonus I suppose.

    I am willing to DO ANYTHING it takes to get these warts to go away for good. If I have to take Tagamet for 5 years and suffer with headaches, I WILL if these dang warts will disappear!!

    Other than that… thats all I’ve got. I will update again in 1 month.

  2. Chris

    I just started taking 800mg of Tagamet 3x day, today.

    I have been thru hell and back with an infestation of warts on my right foot which started out as planters warts on the bottom of my big toe. It quickly developed into about 30 hideous warts on my big toe, and the little toe next to it, and the webbing between. Ugh. Strangely at The same time, I also developed a big ol wart on my right hand. I have never had any skin or wart problems my whole life!!

    At first my dermatologist froze them multiple times which racked up a gigantic Bill $$$ and they just came back bigger, I tried every over-the-counter and old wives tale’s remedy to no avail (duo-film seems to work the best out of any of the over-the-counter products however). Most recently I went to a podiatrist who gives me laser surgery, but they keep coming back, they are super resistant. It is also noteworthy that I’ve always had a crappy immune system. So since Tagamet excites your immune cells, I’m thinking this is my smoking gun.

    I had read about taking tagumet before on the web, but I finally asked my podiatrist about it this past Thursday and he sounded kind of shocked that I knew about it, and said to give it a shot. I’m 34 years old. I know it is said to work better with kids, so I’m crossing my fingers. Wish me luck!

  3. Bob P.
    sarasota, fl

    My son had cauliflower wart for last one year and we tried everything from salicylic acid, compound w, compounded cream and homeopathic drugs, liquid nitrogen, dermatologist specialist, freezing wart, aldara, imiquimod… everything failed… none of the therapy worked … in fact he grew more warts, we were more desperate and more worried.

    We visited this site and saw some positive results with cimetidine and thought to give a try… Professionally I am pharmacist so it was hard to believe, but I got a very positive response. All warts were gone in 3 months… we were giving my son 50mg/kg/day… around 1200-1300 mg per day… we did twice a day so 600-650 mg twice a day.. I have some before and after photo for my records and now warts are gone.. yes my son had 10-15 warts and they all fell off in 3 months.. I tried liquid cimetidine 300mg/5 ml… he also had some flat warts and planters warts on his hand and finger and they are all gone. I appreciate all the help I got from this site.

    • oli

      Hi Bob, my daughter has got about 50 on her body on her face, hands and feet and some on the elbows. She had Wilms Kidney cancer a few years ago so I’m assuming her immune system is not the best. She is 8 years old and the freezing and OTC medications did nothing but make them spread and scarred some on her hands from this barbaric acts.

      We have recently changed doctors and now I’m wanting to attack the virus on two fronts. 1. immune so cod liver oil vit c lysine vit d spuriluina . 2. tagamet (cimitdeine) (magicul) here in Australia. I started her on 600mg a day one in morning and one at night. she is also on her third week of aldara and thats not improving them at all but at least no more have spread.

      Her fingers are constantly wrapped up in duct tape now and tea tree oil every day with regular salt baths but I’m still feeling constantly disheartened with progress.
      she only started taking cimitidiene last week and the multi vitamins two weeks before that. The fingers warts seem to have improved and shrunk since this duct tape treatment but nothing has changed on her face or feet. Do you or anyone else have any other information that could benefit her or some advice ? thanks so much

  4. Lucy

    I started taking Tagamet about a month ago for flat warts on my face. I’m taking 400 mg 3x a day. It seems to be helping. They look better, but now I’m worried about acid rebound and the damage this high dose could cause to my stomach… Anyone with any info would be greatly appreciated.

  5. SP

    Hello all, 2 months ago I started a Tagamet regimen for the treatment of Facial flat warts. I have been taking 1200 mgs/ day religiously… and like many others I had tried absolutely everything before trying Tagamet.
    At first I saw zero difference… I took progress pictures every 2 weeks and I was getting discouraged that there seemed to be no difference.
    Everything changed 2 weeks ago. I had started to notice that all of the warts were getting red, they became ridiculously inflamed and itchy- I looked like a teenage boy with cystic acne… I had no idea what was going on and needless to say I wasn’t a happy camper.
    But believe it or not, after a few days they all started drying out and *poof* like magic my flat warts were all gone. I have some residual scarring but nothing that I can’t handle after what I’ve been through.
    Like many others, I will continue to stay at this dosage for a month and then I will begin to dose down. If you have flat warts and are looking for a solution, please try this. Be patient and don’t give up…

  6. MT

    Hi! I read all the comments about using Tagamet for flat warts and I decided to give it a try. I am a 40 year old women who has been battling flat warts for 8 years. I have a few on my left leg but i have THOUSANDS if not MILLIONS under my left breast and on my abdomen.
    I have literally tried everything!!!!! Salicylic Acid, duct tape, apple cider vinegar, baking soda, lemon, thuja, aldera… I have had them burned off, lasered off….you name it, I have tried it and NOTHING has worked until now. I started taking Tagamet 5 days ago. I am taking 800 mg twice a day. 800mg in the morning and 800mg at night. Well, after day one I notice a big difference and now 5 days later half, if not more of the warts are gone and the ones that have remained look like tiny little pimples. It IS a miracle!
    I can’t wait to see how long it will take for all of them to disappear. I am thinking that at this rate, maybe another 5 days I I will be wart free! I am soooooo happy and excited and relieved!!!! I couldn’t wear a bra all this time… imagine what a nuisance that is! I can’t believe it! I would highly recommend this to any one trying to get rid of flat warts. I am 125 lbs and I am taking 1600mg daily with no side effects whatsoever. I will continue to take this dosage for at least a month after they are all gone just to be sure!

  7. Troy

    I tried the tagamet, at first I thought it was working but when I ran out, it was 4 days till I got more and then progress never resumed. The tagamet also made me feel mildly depressed. The warts were again getting worse and spreading. I finally got rid of warts spreading all over my hands, by cutting them off with some end nipper pliers I modified to cut flush against my skin, dabbing it with pure chlorine bleach, and rubbing in castor oil. In five days the skin healed nearly to it normal prewart condition, rubbing in castor oil daily. By ten days I could not tell where the wart was. I am wart free now and sure thank GOD for castor oil. Its well worth it to cut them off first, takes months if you skip that step. Be sure you wipe thoroughly with bleach the effected area and the tool, so you don’t spread the virus around.

  8. Jaclyn

    Anyone with success using tagamet method:
    Did you notice any physical changes in the warts during treatment (Did they shrink? Change color?) or did you just notice they disappeared one day?

  9. sm

    Wow that is a really high dose.
    Any results or side effects so far?

  10. sm

    Do you remember what your dosage was?

  11. MR

    I have two common warts on the edge of my fingers around my finger nail and they have not gone away for FOUR YEARS OF PERSISTENT DERMATOLOGIST TREATMENT! I also have two plantars warts on my feet. I have used compound w in liquid, gel, and freeze off form. I have gotten them frozen off at the doctor 7 times and have been given injections and beetle juice. I have tried duct tape as well. Nothing has worked. I was just prescribed tagamet and am praying to god this stuff works.

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