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Terbinafine

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Overview

Lamisil is prescribed to treat fungal infections of the toenails or fingernails.

In clinical trials, 70 percent of patients had eradicated fungus from toenails after 12 weeks of treatment; 79 percent had no fungus detectable in fingernails after 6 weeks.

Complete cure rates were lower.

Side Effects and Interactions

Most side effects reported with Lamisil are mild.

They include headache, diarrhea, indigestion, and stomach pain. Liver enzymes occasionally become elevated.

Other side effects may include rash, itching, and changes in the sense of taste.

Contact the physician regarding rash, since some severe skin reactions start as rash.

Serious allergic reactions including trouble breathing and shock (anaphylaxis) have occurred rarely.

Alterations in white blood cell counts have been observed.

Some patients have experienced eye changes and visual disturbances. Any symptoms should be reported to the physician promptly.

Seldane slows metabolism of Lamisil slightly, and Tagamet slows it more (33 percent). This could lead to somewhat higher blood levels of Lamisil.

Rifampin dramatically increases the clearance of Lamisil from the body, leading to lower blood levels.

Lamisil can decrease circulating levels of cyclosporine modestly.

Check with your physician and pharmacist to make sure Lamisil is safe in combination with any other drug you may take.

Special Precautions

Lamisil is not recommended for people with kidney or liver disease.

Liver function tests are appropriate for all patients taking Lamisil for more than 6 weeks.

Taking the Medicine

Lamisil is taken once daily, with or without food.

Fingernail infections are treated for 6 weeks; toenails are treated for 12 weeks.

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Didn't Work ..... Really Worked!
Did this drug work? Average rating: 1/5 (1 votes)
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3 Comments

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After taking Lamisil for approximately 45 days to clear a toenail fungus, my legs have become progressively weaker and painful. I now walk with a cane. I have spoken with two people who have had similar reactions but can find nothing on-line about this side effect. Is there anyone in your audience who has experienced leg weakness and/or pain from taking Lamisil?

Yes. I took it for 90 days and am having horrible pain after finishing. I have been trying to search for adult growing pains, but cannot find anything. Did doc say anything about it?

I took Lamisil for 2 months, and had to stop due to stomach upset and HORRIBLE leg pain. My legs felt like they wouldn't hold me up and I had pains all night, could not get a decent night sleep.

I'm surprised a doctor ordered this pill when the side effects were so awful.The leg pain was intolerable, really. I went off of it for 3 days so far and my legs still ache, but seem to be improving.

I was surprised there is not more information about this problem and side effects on-line. It would have been helpful to read this sooner!

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