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Overview
Tritec is prescribed together with Biaxin to eliminate the germs often
responsible for ulcers, Helicobacter pylori.
It works in part by
suppressing the secretion of stomach acid, but the combination of bismuth with
the antibiotic also works to eradicate the bacteria.
One month of
therapy with Tritec (the first two weeks in combination with Biaxin) usually
gets rid of H. pylori and allows the ulcer to heal. Once the bacteria are gone,
the ulcer does not recur.
Side Effects and Interactions
The combination of Biaxin and Tritec can cause
taste disturbances, diarrhea, nausea, and vomiting in some people.
Other
less common adverse effects may include headache, itching, gynecological
problems, sleep disorders, and chest pain or congestion.
Report any
symptoms to your physician promptly.
If antacids are needed for relief
of ulcer pain, they should generally be taken at a different time, because they
can reduce absorption of Tritec.
Tritec and Biaxin interact; both
increase circulating levels of the other drug. This is probably a therapeutic
advantage when they are being taken together and does not generally require a
dosage adjustment.
Check with your pharmacist and physician before
taking any other medication in combination with Tritec or with the combination
of Biaxin and Tritec.
Special Precautions
Like many bacteria, H. pylori have developed resistance against some of the most commonly used antibiotics.
If an ulcer does not clear after Biaxin/Tritec therapy, the doctor is urged to try a different antibiotic regimen. Resistance to Tritec is uncommon.
Tritec is not recommended for people with severe kidney disease.
This medication should be avoided by people who have had porphyria.
People taking Tritec often report a harmless darkening of the tongue and the stool.
Do not confuse this with the black, tarry stool that indicates intestinal bleeding.
Taking the Medicine
Tritec and Biaxin may both be taken either with or without food.
Tritec is taken twice a
day for four weeks; Biaxin is taken three times a day for the first two weeks.
Do not take
Tritec when you have a hangover.
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