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Overview
Naprosyn is a pain reliever used primarily for arthritis.
Like other nonsteroidal anti-inflammatory drugs, or NSAIDs, it may also be prescribed for menstrual cramps, bursitis, tendinitis, sprains, strains and other painful conditions.
Naprosyn is virtually identical to Anaprox, a popular pain reliever, so these two drugs should never be taken together.
It is also available by its generic name, naproxen, and as an over-the-counter pain reliever, Aleve.
Side Effects and Interactions
No matter how you swallow this medicine, the most common side effects of Naprosyn involve the gastrointestinal tract.
They include nausea, indigestion, heartburn, cramps, gas, constipation, and diarrhea.
Some people may develop ulcers and intestinal bleeding while taking Naprosyn. Occasionally these problems can occur without obvious symptoms and lead to a life-threatening crisis due to perforation of the stomach lining.
Older people appear to be more susceptible to this problem and should be monitored carefully. Warning signs include weight loss, persistent indigestion, a feeling of fullness after moderate meals, dark or tarry stools, anemia and unusual fatigue.
Home stool tests such as Hemoccult or Fleet Detecatest may provide an early indication of bleeding.
Other side effects to watch for include headache, ringing in the ears, rash, itching, difficulty breathing and fluid retention.
Drowsiness, dizziness, lightheadedness, difficulty concentrating, and confusion are possible, so do not drive if you become impaired.
Less common adverse reactions include jitteriness, insomnia, heart palpitations, hair loss, depression, tremor, tiredness, visual disturbances, and sores in the mouth. Report any symptoms to your physician promptly.
Naprosyn can affect both the kidney and liver, so periodic blood tests to monitor the function of these organs is important.
Some people become sensitive to sunlight while on Naprosyn, with a severe burn or rash resulting, so use an effective sunscreen, stay covered or avoid the sun.
This medication can interact with many other drugs, including aspirin and alcohol.
Naprosyn may blunt the effectiveness of many blood pressure medicines, including beta-blockers like Corgard or Tenormin, ACE inhibitors like Capoten, Vasotec or Zestril and diuretics like Dyazide or Lasix.
It can increase blood levels of the heart drug Lanoxin and increase the toxicity of the transplant drug Sandimmune and the cancer medicine methotrexate.
Because it has the potential to cause GI bleeding, Naprosyn could be dangerous in combination with the blood thinner Coumadin.
If you must take Naprosyn together with either the seizure medication Dilantin or the manic-depression medicine lithium, your physician should monitor blood levels and effects of these drugs closely.
Check with both your doctor and your pharmacist before taking Naprosyn in combination with any other drugs.
Special Precautions
People who are allergic to aspirin or other anti-inflammatory agents should avoid Naprosyn.
Signs of allergy include breathing difficulties, rash, fever, or a sudden drop in blood pressure and require immediate medical attention.
Taking the Medicine
Because Naprosyn can be hard on the digestive tract, it may be taken with food to reduce stomach irritation. This offers no guarantee of safety, however.
Did this drug work? Average rating: 2.4/5 (43 votes)
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How safe is it to take 4000mg a day of naproxen?
and how long does it take to completely get out of your system once stopped, after taking that amount for over 9yrs?
does anyone know if the kidneys will repair themselves?
Extreme stomach pain from 500 mg. of prescribed naproxen twice a day. Bloating to the point that I look like I am about to give birth to a child. Incredibly scary!!!
I have been taking Naproxen and it helped the first day or two. I am taking 500mg twice a day, but only for 7 days. I haven't noticed any problems except it does not work very well for me.
Taken 500 MG three days, one in the morning and once at night. Sick beyond belief. Rash, stomach pain, ringing in my ears, bloated. Will never take it again... if I live.
I'm 72 years old and took Aleve for 3 days to relieve arthritis pain. I am now under care of a gastroenterologist for a severe attack of pancreatitis from use of this medication. Beware if you have ever had a problem with your stomach taking aspirin!
I have been taking 500 mg naproxen for almost 2 years. It was prescribed by my doctor for my terrible period cramps and if i catch it in time it always helps. I take one pill 2 times per day @ 500mg, you need to eat a big meal especially if you're tiny like me because it can really upset your stomach. I have recently been taking it for severe shoulder pain (could be bursitis, tendinitis, arth, combination of all not sure yet) but it does not help.
I have read it takes about 72 hours to get fully out of your system. Do not drink or take advil/aleve it can cause major complications. Also, it increases your chances of getting a peptic ulcer which I think I may have also so I have stopped taking them for the shoulder pain and just for menstrual cramps when needed.
I have had double knee replacement { 5 years Ago } and had severe pain every day, tried Naproxen, didn't help. I am on Celebrex with great improvement.
When I take naproxen I have a bad headache in the morning. So I take aleve @ night wake up clear headache.
My husband took Aleve for a number of years for arthritis pain. About ten years ago, his doctor did a 24-hour urine test and found his kidneys were functioning at about 30 percent. They are now functioning at about 20% - if he were younger he would be ready for dialysis at 15%. But he is too old for dialysis. His nephrologist says the Aleve is the direct cause of the kidney destruction.
I took naproxen 500 twice a day for disc problem in my lumber spine. Instead of helping with the pain I've not got problem with my ears ringing. I think its called tinnitus. Can't hear the sirens from police cars.
I experienced excessive sweating, high blood pressure, palpations, nervousness, panick attacks, confusion, you name it. Doctors should be careful how they prescribe this drug.
Like others who have posted - I took Naproxen. It was prescribed by my primary care doctor - who is a sports medicine specialist - for pain in my ankle. (I had micro-fracture surgery on the ankle one year ago, still have pain and swelling as well as tendinitis.) Doc had hoped the Naproxen might help. 500 mg - twice a day.
Today (day 9 of treatment) caused a call to the doctor and I stopped the med. Had elevated blood pressure, nausea, diarrhea, and generally did not feel right (chest "something" but not pain exactly). Covering doc gave me instructions and I've been taking it easy today. Finally, 15 hours later, I feel more like myself and my blood pressure is back down (was within a few hours). Don't think I will take this drug again - and it didn't even help the ankle pain that much.
I started taking 500mg naprosyn 2 times a day for tennis elbow issue. I didn't notice initially, but had ankle and fingers swelling. After 1st refill I noticed my elbow wasn't as painful but now was having forearm and upper arms muscles spasms. I couldn't raise my arm to take a bite of food the pain was too much. Then the joint pain and tiredness began and I noticed bloating. Checked the side effects and stopped meds after 6 weeks. After 3 days I still feel bad. How long till the naprosyn is out of my system?
Hi, its taken me about 6 weeks to get it out of my system, drinking plenty of water helps to flush it out, hope this helps, I had severe reactions to naproxen, so its taken a few weeks for me. Everybody is different hope this helps
Bee
Got numbing in my left jaw, and left arm, weird feelings in my legs, swelling of the hands, dizziness and headaches after taking only 3 of these pills. I stopped right after the 3rd one.
Have been taking Naproxen for 1 1/2 weeks as of today. Started out fine - relieved my lumbar and nerve pain. Today is day 13 (refilled my script) and I am absolutely miserable. I have severe bloating, abdominal pain, constipation and am overall feeling depressed. I am minutes from the ER.
I do not know how long this feeling will take to leave me, but I am becoming anxious and scared. Trying to drink water to help flush this medicine out. Will NEVER take it again. Calling the doc in the morning to help find another pain medicine or I just might stick to ibuprofen which I have never had a problem with in the past. WARNING to anyone who is prescribed this med.
I was on naproxen for only 3 days, 500mg, twice a day. Almost immediately my stomach felt crampy, and have had such bad indigestion (that I felt as high as my shoulder and as low as my lower ribs) that it woke me up at night. It did, however, help the pain for the plantar faciitis(sp?) for which it was prescribed, but not worth it!! I will never take this again if I can help it. By the way, I have had no previous problems with any medication before, ever.
My husband was just released from the hospital as a result of using this drug. He used it exactly as prescribed, and it still caused more trouble than it was worth. He had severe gastrointestinal bleeding, so bad that he needed a blood transfusion with 3 units of blood. He was in ICU for 4 days. It was prescribed for tendonitis, but definitely was not worth it! The doctor and nurses all said that almost everyone who takes this stuff ends up with gastrointestinal bleeding. It's bad stuff in my opinion!
I have taken 2 Aleve everyday for 6 years and have lots of trouble sleeping, headaches and now a rash for the past 6 months. I am stopping it today after trying to figure out what this rash is. I think I am poisoning myself!
The same thing happened to me. Please let me know if you have any solutions for this. The doctor prescribed me Dexilant, but I haven't seen much difference :(
I took Aleve for my endometriosis pain...from Thursday to Monday. It worked GREAT!
Except, on Monday, when I took 2 pills without food (yea, my bad), I got so bloated and HORRIBLE GAS PAINS and abdomen was tender! I wanted to die! My period craps weren't as bad.
It's now Wednesday and I'm feeling a bit better. Abdomen is a bit tender still, but I am able to breath and walk. I took yesterday off from work to rest.
Never taking this again. I'm going to modify my diet to help with my endo. This drug is CRAZY! I've never had that reaction to it and I used to take it twice a day for YEARS. (Years ago).
Anyone know how long it takes for the drug to leave our systems?
I have had a heel spur for a number of years now. Of course, the heel spur lead me to get steroid injections over a period of time which helped. BUT, as a result of the injections (that I later learned that one to many was far too much), my heel bone is now damaged as a result of the numerous injections. Just out of no where I began to have excruciating pain, 10X worse than the heel spur. It felt as though the bone was broke inside of my foot and was about to come out.
I began to take the Naproxin 500mg. as previously prescribed, and boy what a difference. I have not so far experienced any stomach pain as I eat a yogurt or some food first that would (I guess) coat my stomach. This medication on a scale of 1-10 with 10 being the highest for alleviating pain--worked at a 10 within one day!
My pain went down to a one. My pain was so severe that I was on my way to the emergency room. I really thought the bone in my foot was broken or twisted. I presently reside in NY, and I walk a lot. The pain that I experienced actually stopped me in my tracks (while getting off the bus). I just wanted to share my personal experience so that others will perhaps give this medication the opportunity to work on any issue where inflammation is part of the root cause of pain. I think one should coat the stomach by eating first, and then take the medication.
Perhaps ice cream or some heavy food would help those who have experienced the pain. Again, this worked and I am so thankful that I can now walk up and down the stairs in my house.
Has anyone else had swelling and pain in the gums after taking this? And headaches plus pain between the eyes at the top of the nose?
Report it to your Doctor and don't take any more.
'took 3 doses of Naprosyn with food over the weekend (doctor prescribed it to use as needed) and weighed 4 lbs heavier on Monday than I did on Friday--and I had been watching my intake and exercising more over the weekend! I am bloated and constipated and the weight is persistent after 72 hours. As a regular, heavy exerciser, I drink plenty of water and liquids and am reducing my calories to see if this weight will budge. I will not be taking this drug again.
I, too, wonder how long this will take to dissipate?
My 79 year old mother has had severe osteoarthritis pain. She was given Aleve. She now has severe swelling and pain in her arms, hands, neck and shoulders. She has stopped the Aleve, but I am very worried about her. She called the nurse help line ( we have these in Canada), and they had her go see her doctor the next morning. He checked her over, and gave her a pain med., but has not told her how long before this horrible reaction is out of her system. My poor mom, all this pain for her osteoarthritis, and now this on top of it all.
I took one dose of Naproxen with food this morning, and almost immediately felt indigestion which has lasted all day. Am also feeling bloated, gassy, nauseous and constipated. It has relieved the tendonitis pain, but I will take my chances with Advil instead of chancing worsening of the side effects from this drug after reading the comments here and experiencing all this from just one pill.
I took 500 mg naproxen for 1 day and now suffering from severe stomach pain diarrhea and constipation and severe nausea. I haven't been able to eat for 2 days now. Does any one know how long the side effects last?