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Naproxen

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Overview

Naprosyn is a pain reliever used primarily for arthritis.

Like other nonsteroidal anti-inflammatory drugs, or NSAIDs, it may also be prescribed for menstrual cramps, bursitis, tendinitis, sprains, strains and other painful conditions.

Naprosyn is virtually identical to Anaprox, a popular pain reliever, so these two drugs should never be taken together.

It is also available by its generic name, naproxen, and as an over-the-counter pain reliever, Aleve.

Side Effects and Interactions

No matter how you swallow this medicine, the most common side effects of Naprosyn involve the gastrointestinal tract.

They include nausea, indigestion, heartburn, cramps, gas, constipation, and diarrhea.

Some people may develop ulcers and intestinal bleeding while taking Naprosyn. Occasionally these problems can occur without obvious symptoms and lead to a life-threatening crisis due to perforation of the stomach lining.

Older people appear to be more susceptible to this problem and should be monitored carefully. Warning signs include weight loss, persistent indigestion, a feeling of fullness after moderate meals, dark or tarry stools, anemia and unusual fatigue.

Home stool tests such as Hemoccult or Fleet Detecatest may provide an early indication of bleeding.

Other side effects to watch for include headache, ringing in the ears, rash, itching, difficulty breathing and fluid retention.

Drowsiness, dizziness, lightheadedness, difficulty concentrating, and confusion are possible, so do not drive if you become impaired.

Less common adverse reactions include jitteriness, insomnia, heart palpitations, hair loss, depression, tremor, tiredness, visual disturbances, and sores in the mouth. Report any symptoms to your physician promptly.

Naprosyn can affect both the kidney and liver, so periodic blood tests to monitor the function of these organs is important.

Some people become sensitive to sunlight while on Naprosyn, with a severe burn or rash resulting, so use an effective sunscreen, stay covered or avoid the sun.

This medication can interact with many other drugs, including aspirin and alcohol.

Naprosyn may blunt the effectiveness of many blood pressure medicines, including beta-blockers like Corgard or Tenormin, ACE inhibitors like Capoten, Vasotec or Zestril and diuretics like Dyazide or Lasix.

It can increase blood levels of the heart drug Lanoxin and increase the toxicity of the transplant drug Sandimmune and the cancer medicine methotrexate.

Because it has the potential to cause GI bleeding, Naprosyn could be dangerous in combination with the blood thinner Coumadin.

If you must take Naprosyn together with either the seizure medication Dilantin or the manic-depression medicine lithium, your physician should monitor blood levels and effects of these drugs closely.

Check with both your doctor and your pharmacist before taking Naprosyn in combination with any other drugs.

Special Precautions

People who are allergic to aspirin or other anti-inflammatory agents should avoid Naprosyn.

Signs of allergy include breathing difficulties, rash, fever, or a sudden drop in blood pressure and require immediate medical attention.

Taking the Medicine

Because Naprosyn can be hard on the digestive tract, it may be taken with food to reduce stomach irritation. This offers no guarantee of safety, however.

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104 Comments

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How safe is it to take 4000mg a day of naproxen?
and how long does it take to completely get out of your system once stopped, after taking that amount for over 9yrs?
does anyone know if the kidneys will repair themselves?

Extreme stomach pain from 500 mg. of prescribed naproxen twice a day. Bloating to the point that I look like I am about to give birth to a child. Incredibly scary!!!

I have been taking Naproxen and it helped the first day or two. I am taking 500mg twice a day, but only for 7 days. I haven't noticed any problems except it does not work very well for me.

Taken 500 MG three days, one in the morning and once at night. Sick beyond belief. Rash, stomach pain, ringing in my ears, bloated. Will never take it again... if I live.

I'm 72 years old and took Aleve for 3 days to relieve arthritis pain. I am now under care of a gastroenterologist for a severe attack of pancreatitis from use of this medication. Beware if you have ever had a problem with your stomach taking aspirin!

I have been taking 500 mg naproxen for almost 2 years. It was prescribed by my doctor for my terrible period cramps and if i catch it in time it always helps. I take one pill 2 times per day @ 500mg, you need to eat a big meal especially if you're tiny like me because it can really upset your stomach. I have recently been taking it for severe shoulder pain (could be bursitis, tendinitis, arth, combination of all not sure yet) but it does not help.

I have read it takes about 72 hours to get fully out of your system. Do not drink or take advil/aleve it can cause major complications. Also, it increases your chances of getting a peptic ulcer which I think I may have also so I have stopped taking them for the shoulder pain and just for menstrual cramps when needed.

I have had double knee replacement { 5 years Ago } and had severe pain every day, tried Naproxen, didn't help. I am on Celebrex with great improvement.

When I take naproxen I have a bad headache in the morning. So I take aleve @ night wake up clear headache.

My husband took Aleve for a number of years for arthritis pain. About ten years ago, his doctor did a 24-hour urine test and found his kidneys were functioning at about 30 percent. They are now functioning at about 20% - if he were younger he would be ready for dialysis at 15%. But he is too old for dialysis. His nephrologist says the Aleve is the direct cause of the kidney destruction.

I took naproxen 500 twice a day for disc problem in my lumber spine. Instead of helping with the pain I've not got problem with my ears ringing. I think its called tinnitus. Can't hear the sirens from police cars.

I experienced excessive sweating, high blood pressure, palpations, nervousness, panick attacks, confusion, you name it. Doctors should be careful how they prescribe this drug.

Like others who have posted - I took Naproxen. It was prescribed by my primary care doctor - who is a sports medicine specialist - for pain in my ankle. (I had micro-fracture surgery on the ankle one year ago, still have pain and swelling as well as tendinitis.) Doc had hoped the Naproxen might help. 500 mg - twice a day.

Today (day 9 of treatment) caused a call to the doctor and I stopped the med. Had elevated blood pressure, nausea, diarrhea, and generally did not feel right (chest "something" but not pain exactly). Covering doc gave me instructions and I've been taking it easy today. Finally, 15 hours later, I feel more like myself and my blood pressure is back down (was within a few hours). Don't think I will take this drug again - and it didn't even help the ankle pain that much.

I started taking 500mg naprosyn 2 times a day for tennis elbow issue. I didn't notice initially, but had ankle and fingers swelling. After 1st refill I noticed my elbow wasn't as painful but now was having forearm and upper arms muscles spasms. I couldn't raise my arm to take a bite of food the pain was too much. Then the joint pain and tiredness began and I noticed bloating. Checked the side effects and stopped meds after 6 weeks. After 3 days I still feel bad. How long till the naprosyn is out of my system?

Hi, its taken me about 6 weeks to get it out of my system, drinking plenty of water helps to flush it out, hope this helps, I had severe reactions to naproxen, so its taken a few weeks for me. Everybody is different hope this helps
Bee

Got numbing in my left jaw, and left arm, weird feelings in my legs, swelling of the hands, dizziness and headaches after taking only 3 of these pills. I stopped right after the 3rd one.

Have been taking Naproxen for 1 1/2 weeks as of today. Started out fine - relieved my lumbar and nerve pain. Today is day 13 (refilled my script) and I am absolutely miserable. I have severe bloating, abdominal pain, constipation and am overall feeling depressed. I am minutes from the ER.

I do not know how long this feeling will take to leave me, but I am becoming anxious and scared. Trying to drink water to help flush this medicine out. Will NEVER take it again. Calling the doc in the morning to help find another pain medicine or I just might stick to ibuprofen which I have never had a problem with in the past. WARNING to anyone who is prescribed this med.

I was on naproxen for only 3 days, 500mg, twice a day. Almost immediately my stomach felt crampy, and have had such bad indigestion (that I felt as high as my shoulder and as low as my lower ribs) that it woke me up at night. It did, however, help the pain for the plantar faciitis(sp?) for which it was prescribed, but not worth it!! I will never take this again if I can help it. By the way, I have had no previous problems with any medication before, ever.

My husband was just released from the hospital as a result of using this drug. He used it exactly as prescribed, and it still caused more trouble than it was worth. He had severe gastrointestinal bleeding, so bad that he needed a blood transfusion with 3 units of blood. He was in ICU for 4 days. It was prescribed for tendonitis, but definitely was not worth it! The doctor and nurses all said that almost everyone who takes this stuff ends up with gastrointestinal bleeding. It's bad stuff in my opinion!

I have taken 2 Aleve everyday for 6 years and have lots of trouble sleeping, headaches and now a rash for the past 6 months. I am stopping it today after trying to figure out what this rash is. I think I am poisoning myself!

The same thing happened to me. Please let me know if you have any solutions for this. The doctor prescribed me Dexilant, but I haven't seen much difference :(

I took Aleve for my endometriosis pain...from Thursday to Monday. It worked GREAT!

Except, on Monday, when I took 2 pills without food (yea, my bad), I got so bloated and HORRIBLE GAS PAINS and abdomen was tender! I wanted to die! My period craps weren't as bad.

It's now Wednesday and I'm feeling a bit better. Abdomen is a bit tender still, but I am able to breath and walk. I took yesterday off from work to rest.

Never taking this again. I'm going to modify my diet to help with my endo. This drug is CRAZY! I've never had that reaction to it and I used to take it twice a day for YEARS. (Years ago).

Anyone know how long it takes for the drug to leave our systems?

I have had a heel spur for a number of years now. Of course, the heel spur lead me to get steroid injections over a period of time which helped. BUT, as a result of the injections (that I later learned that one to many was far too much), my heel bone is now damaged as a result of the numerous injections. Just out of no where I began to have excruciating pain, 10X worse than the heel spur. It felt as though the bone was broke inside of my foot and was about to come out.

I began to take the Naproxin 500mg. as previously prescribed, and boy what a difference. I have not so far experienced any stomach pain as I eat a yogurt or some food first that would (I guess) coat my stomach. This medication on a scale of 1-10 with 10 being the highest for alleviating pain--worked at a 10 within one day!

My pain went down to a one. My pain was so severe that I was on my way to the emergency room. I really thought the bone in my foot was broken or twisted. I presently reside in NY, and I walk a lot. The pain that I experienced actually stopped me in my tracks (while getting off the bus). I just wanted to share my personal experience so that others will perhaps give this medication the opportunity to work on any issue where inflammation is part of the root cause of pain. I think one should coat the stomach by eating first, and then take the medication.

Perhaps ice cream or some heavy food would help those who have experienced the pain. Again, this worked and I am so thankful that I can now walk up and down the stairs in my house.

Has anyone else had swelling and pain in the gums after taking this? And headaches plus pain between the eyes at the top of the nose?

Report it to your Doctor and don't take any more.

'took 3 doses of Naprosyn with food over the weekend (doctor prescribed it to use as needed) and weighed 4 lbs heavier on Monday than I did on Friday--and I had been watching my intake and exercising more over the weekend! I am bloated and constipated and the weight is persistent after 72 hours. As a regular, heavy exerciser, I drink plenty of water and liquids and am reducing my calories to see if this weight will budge. I will not be taking this drug again.

I, too, wonder how long this will take to dissipate?

My 79 year old mother has had severe osteoarthritis pain. She was given Aleve. She now has severe swelling and pain in her arms, hands, neck and shoulders. She has stopped the Aleve, but I am very worried about her. She called the nurse help line ( we have these in Canada), and they had her go see her doctor the next morning. He checked her over, and gave her a pain med., but has not told her how long before this horrible reaction is out of her system. My poor mom, all this pain for her osteoarthritis, and now this on top of it all.

I took one dose of Naproxen with food this morning, and almost immediately felt indigestion which has lasted all day. Am also feeling bloated, gassy, nauseous and constipated. It has relieved the tendonitis pain, but I will take my chances with Advil instead of chancing worsening of the side effects from this drug after reading the comments here and experiencing all this from just one pill.

I took 500 mg naproxen for 1 day and now suffering from severe stomach pain diarrhea and constipation and severe nausea. I haven't been able to eat for 2 days now. Does any one know how long the side effects last?

I've had severe problems with both my feet. I took 2 Aleve, 220 mg. each, every other day (enough for me as I'm a lightweight when it comes to drinking and drugs), for about 6 months. During that time I felt bloated, tired, constipated, depressed, and swollen, but the positive effects definitely outweighed the negative effects. I decided to wean myself from it after reading so many negative things about it, and I thought that my foot problem was improving. However, after 3 days of not taking Aleve, I believe, I couldn't sleep all night because of intense itching and burning. I couldn't stand it and ended up taking Aleve again. I tried again to quit it, and for days I had to go through severe itching.

I started taking Aleve again in the middle of May for my foot problems (could barely walk), and it worked wonders to relieve me of nerve pain in my feet. However, the same side effects returned. I'm now weaning myself from it again and the awful itching and burning have come back. Although I still have nerve pain in my feet and have difficulty walking, I'm going to see if I can keep off of this drug. I've also experienced upset stomach with it. It's very difficult to stay off of it once it's in the system. It works very well to numb the nerves in my feet, but I don't trust it at all.

I am 16 years old, and I've been prescribed Naproxen for my joint hypermobility, and I am currently in bed with severe abdominal pain, I have a headache, nausea, and I just feel run down. I cannot concentrate, and even though the stomach pains are keeping me awake I still feel dizziness and sleepiness. And the worst thing, is that I have a GCSE History exam this afternoon.

Well, for me naproxen has works. I was getting such cramps and I only took it for two days and the pain went away my pain was so bad I couldn't even walk. But remember everyone's body is different not everyone will have a negative impact on this medication. I also have a friend that takes it and has positive feed back on this medication this medication also works on her. We both work in the medical field.

Glad I found these comments, I am not alone in what I am experiencing!
I have been taking Naproxen 500mg twice a day for a over a week, and previously 250mg for a week before that.

This past week I have had stomach cramps, heart palpitations and have gained over 3kgs (I have been on a weight loss program for 12mths losing 22kgs and still on it but gained the 3kgs since taking these drugs) I get the worst hunger pains too!

I am not going to take them anymore and if my pain returns will have to find an alternative pain relief.


I've been prescribed Naproxen for period pains I'm 19 and have taken it for 3 cycles now and I couldn't understand why the pain was getting worse then I realized that the pain was being caused by the gas I have slight chest pain and lower abdominal pain and I feel very nauseous and constipated, I just want to curl up and die. Before I was prescribed Naproxen, I tried Feminax Ultra which is the same just under a different name and I told the doctor it didn't work at the time I didn't realize Feminax and Naproxen were the same but I am angry at the doctor for giving me a prescription even when I stated it didn't work at the time I had suffered no side effects...

I will be calling the doctor later for an emergency appoint because if the pain doesn't go soon I think I will just die I have work tomorrow morning and if I feel like this I wont be able to go in which really sucks cause I need the hours... Never again will I touch this drug it has been the worst experience of my life...

I've been taking naproxen for 2 and a half years, I'm in my mid teens, I take it as-needed for headaches and occasional cramps, its 500mg. one for headache, two for cramps. I normally do NOT experience any side effects. When I took aspirin as a substitute for headaches it seems it only gets worse and I have a terrible stomach pain on acation and my skin takes longer to heal if I get a scratch is is quite more painful than normal, can I get some insight please?

I've been prescribed Naprosyn 250mg twice a day for my lower back ache and I have just taken 3 pills so far. I got instant relief from pain after the first pill itself. However, even since that I have been sweating excessively and not able to sleep all night. I'm planning to stop it and check with my doctor again. Not sure how long it will take to flush these 3 pills out.

I have seriously bad cramps during my period so I take either tylenol, ibuprofen, or aleve, but always with a meal except for tylenol can be taken with just water. I never had a problem. Been taking for 20 yrs but only as needed, 2-3 days a month. I believe tylenol affects the liver and the other two affects the kidneys so I think its good to switch around, give the other organ a break. But I would never take these drugs everyday.

I try to drink a lot of tea to flush out my kidneys after taking aleve or ibuprofen. I think many people do not eat enough, and these can cause stomach problems. Take tylenol if u cant eat. Like in the middle of the night I take tylenol for my cramps and go back to bed. For women, don't drink anything cold or eat anything cold while on your period, no fruits, dairy, if you suffer cramps. It makes it worse for me. Only warm foods and fluids.

I got prescribed them on Friday and I took the as stated on the Leaflet and by what my doctor said and I am on the pill as well and the pill I'm on stops my periods now I've bin on this pill for well over a year now so I know I don't have periods on it and I took the naproxen as stated and I have bled really bad can't move out of bed coz of pain in my stomach and I have really bad wind because of it feel really sick and have diarrhoea really bad I can't sleep either. I mean I have broke my ankle twice and the first time I walked home on it the second I hopped into my house and got my mum to ring an ambulance and I didn't cry when that happened and now this pain brings me to tears its that painful the doctor said I gotta take twice a day for the next four weeks but I won't last that long I don't think

I will never take this drug again only took it for 2 weeks now I have severe tinnitus and deafness I am furious please don't take it.

I injured my wrist at work in April 2009 and was prescribed Novo-Naproxen 500Mg 2 times a day since. I have just recently started getting an (upset Stomach) sick feeling to the point it feels like I want to throw up, I have read online that they might cause ulcers and other problems so I stopped taking them Sept 20, 2012 as they don't seem to do anything anyways for the damage caused in the injury (OSTEO-NECROSIS) of the lunate bone in my left wrist and I have just started getting aches in my shoulder to the point I have a hard time lifting my arm and have complete numbness in my hand to the point I can poke my hand with a pin and not feel it go in when I sleep and takes a couple mins to get feeling back.

My mother was prescribed naproxen for back pain and apparently they caused kidney deterioration she is 77 and the doctor asked why she was given the prescription at her age and told her to take Tylenol extra strength.

I'm taking naproxen but I hate pills... but I prefer pills over scramps..... just like the other lady said feels like I'm about to have a baby. That's super painful.. I couldn't take the pain so I went to sleep.... When I woke up the pain was even worst... Barely could move or really eat...

I normally eat a lot for a little person but not on this medicine.. 2-4 spoon fills and that's it.. I really believe I need a better doctor or something... Its really messing me up at school 5days out of the month.... Sometimes I cry it's so painful...I love side... he is so helpful and understanding.... but yea I believe it's time for a new doctor

I'm 26 and I started taking naproxen 1000mg slow release once a day a few wks ago due to having an accident at the pool and chocking on water causing sharpe chest pain. I took it for two wks. The first few days it helped but then after the wk I started developing extreme reflux, heartburn, indigestion problems. I took anti acids straight away which helped but didn't put two and two together so kept taking naproxen into the following wk. my symptoms got worse! I then developed difficulty sleeping/anxiety/headaches-migraines/heart palpitations which I did not have prior. These were mild but then when I played sport got quite extreme to the point I was sooo worried in case I had a heart attack.

I went back to the Dr who advised me to stop taking it and just have anti acid tablets, watch what I eat and drink plenty of water until it passed! I also had to wear a heart monitor. It's now been another wk after taking it and I'm still experiencing reflux severely and palpitations when my heart rate increases.

I'm meant to be going away tomorrow playing in a tournament and I'm so scared to exert myself in case the palpitations come back. Plus I'm in severe pain after I eat and just in general. Possibly due to ulcer?? Back to Dr today.

Has anyone else had ongoing side effects like mine after ceasing this medication and how long did it take to pass from your system or did it leave long term side effects with you and if so what did u do for the palpitations/heart burn?

I am coming off naproxen after 4 years will I have any side effects?

my doctor has told me to stop taking naproxen because of diahrea and stomach pains will i have any side efects after taking it for 4 years.

My doctor gave me Naproxen after recently having a car accident to reduce the pain in my neck and back. I was instructed to take 2 500mg tablets per day. After taking only 2 of these tablets, I woke up in the middle of the night with severe pains in my stomach. I went to A&E and they took me off the tablets and gave me Omprazole. 4 days on I'm still having stomach pains but they have now reduced.. will never take Naproxen again..

I have been taking naproxen for 7 days for osteoarthritis in my hip. 500 mgs 2x a day. It has helped a lot with the pain, but now my lips are swollen with the corners cracking.

I have been taking Naproxen for 15 years since I was twelve, on a daily basis for two weeks out of every month. I find it is really helpful for cramping, although my stomach is really week now and I think it is the cause of my IBS. haha although the doctor insisted Naproxen does not hurt the stomach and just upped my dosage! I think I'll change doctors. It does work for swelling and pain though. I recommend always eating and drinking a full glass of milk with every take. I didn't do this when I was younger (my doctor didn't advise me) and now my stomach tolerance is terrible. Eat with it! :)

My GP put me on Naproxen in Jan 2012 because my normal arthritis tablets were not available. Around beginning of March 2012 I noticed that my left thumb became numb. At the end of March beginning of April the numbness had spread to all the fingers on both hands. I was diagnosed with Carpel Tunnel, even though I insisted that I only had numbness of the fingers and NOT pins and needles.

I had my right hand carpel tunnel op at end of June and my left hand op at end of September. - My fingers are still numb. I looked up the side effects of Naproxen a few weeks ago and found under the 'rare side effects' - 'numbness of hands or feet'. I immediately stopped taking Naproxen (3 weeks ago) my little finger and ring finger on my left hand seem to have come back to life and I am hoping that all my fingers will do so once the Naproxen is completely out of my system but do not know how long this will take. I have not told my GP of this yet as am waiting to see what happens.

The first time I used it I was sick for 2 days. I tried it again for shoulder pain but this time took it with a big meal and was able to tolerate it. The last time I took it I broke out in hives on my face. Also got an ulcer on my tongue. This is some nasty stuff. I'm done with it.

I took naproxen for only 2 days and in that time I experienced non stop pain in my chest and in my abdomen as well as a sore throat. I experienced bloating and gas. I rather have the bursitis and arthritis in my hip. I threw the perscription away and will prayerfully consider before taking any perscription again.

Hi,i am not %100 sure yet but after much research I believe my new found e.d. Is being caused by the naproxen, I will not be sure until my doctor appt in 2 week's but from what I have read it can cause this & I'm way too young to get a problem like this & am just warning people of the possibility of this happening, they don't tell you about this possibility on the label & it's not cool, so beware & do your research on all med's, I wouldn't wish this on any one. if you are a guy you will understand & yes it can happen to you. Beware beware beware please be careful you do not want this & I think I finally figured it out & I for one will live with the constant pain to have the ability to once again have an erection without more meds.
thank you
Jeff

PEOPLE'S PHARMACY RESPONSE: If you confirm the connection, be sure to report it to the FDA MedWatch and here. It has not been reported before.

Was taking aprosyn and tramadol together post surgery. What a mistake. Constant reflux, with flu symptos and to make matters worse getting cramp style pain in my leg and shoulder. This is my 4th night that I have not slept.... will never take these tablets again.. do not know how long it it will be until these tablets are out of my system.

I am 16 and taking naproxen for bad hypermobility. I had really severe stomach pains in the left side. I left it for a couple of days to see if it would ease off but never did. The doctor told me that naproxen had thinned the lining of my stomach and caused my stomach acid to burn my stomach. Had to stop the naproxen but my stomach was worse by that time so I am still getting the pains after being off naproxen for over a month.

I'm 67 and I have had the same bad side effects from taking naproxen as all the other comments here. I was prescribed the anti inflammatory for a foot problem called Naroma. The doc never mentioned the side effects but I did read the directions & took it with food & a full glass of water (even milk). That doesn't really help the stomach pain much and also had headaches. I awoke at night thinking I might be having a heart attack so I even put on my nicest PJs just in case!

I've always had low BP less than 120/80 and it shot up to 156/84. I was really scared so I called my doc after 7 days on this poison and she changed my med to another nsaid called Mobic, but before going to pick it up I looked on line & found it has similar side effects. I called & cx'd the order, I'd rather live with foot pain than have a stroke or heart attack from these horrible pills!

Took Neproxin last night for the first time for a finger tendonitis and woke up at 4;30 in the morning with sever lower left abdominal intestinal pain which is still continuing 5 hours later.

Have never had any stomache problems a havy always been very healthy. A vegan and tournament sports player. I worry I may have some ulcer or intestine injury and was not told of possible side effects before taking.

Now I read the potential problems with this stuff and wonder WHY WOULD ANYONE MAKE THIS........ It's like some kind of cosmic joke or something..... I'm pretty upset and if I am still alive I will likely contact the manufactures to give a piece of my mind.

I have been on this tablet for a week and half I have problems now with pain I can't tolerate I am swollen and my stomach is four times as big!

My thirst is great and I can't sleep I can't stand up for my stomach is so painful! I feel so upset I was on diclofenic and was ok but doc said its bad for you I was on that without any problems for 20years I am so mad about this I have enough problems without this. I to have ringing in my ears and my eyesight is funny I am struggling to write this so if I spell anything wrong sorry. I am dizzy and hot please someone tell me if these simtoms are gonna go away please I have not had one fora day and a half and I still can't sleep and am shakey my legs are swollen also. I will never trust my doctor again, why are they giving this out I would love to know!!! Can some one write on here and say if this will go away thank you

I'm a 40 yr old female n have been reading the comments on here. I was not given instruction on the dangers of this drug n the leaflet doesn't explain much either. My doc has told me to come off them now eight months after starting taking them 500 mg twice daily. I'm now unable to work for the last twenty eight weeks with ringing in my ears, dizziness, hospitalisation for chest pains and seizers, cramps in my left leg, numbness on my right side, vaige memory loss, flatulence, intergestion, insomnia for days followed by long sleep periods, collapsing, pains in my head n feels like something pops but doesn't show on m.r.i. scan, stuttering, I'm now under a neurologist and physio, can't drive n have a child to care for with special needs.

The drug did get rid of the pain. Now I'm coming off everything is heightened plus now I go to the loo much more and am in pain, suffering very bad stomach cramps that double me over and am very weak I wish I had never been prescribed it. I could have used something else for the lower back and shoulder pain. To top it of the Dr now wants me to see a councilor because they want to put it down to depression.

I was prescribed Naproxen 500 mg for inflammation in shoulders. I took them with big meals and plenty of water, 1 tablet twice a day. Early on, I had pain on front right neck, left ear pain and left side migraine. But stupid of me I continued in hope of finishing my medicine to heal my shoulder injury.

On the 5th day, after finishing 8 tablets and getting burning stomach feeling and diarrhea, I stopped taking them. I also have anxiety, now I have a lot of worrying to do, like if I have ulcer or not. With this anxiety, I will for sure get my GP to book me an appointment with a GI. Sucks!

Taken off Diclofenac because of risk of heart attack. Never had a problem with it and it worked well. After 24 hours on Naproxen 500mg, had awful heartburn and weird dreams, so stopped taking it. Tried again after a week and followed instructions really carefully. After 36 hours suddenly developed really bad heartburn. After a sleepless night with the sensation of my rib cage exploding from pressure and burning pain, stopped taking it.

Now 24 hours later, still trying to deal with the pain and wind. HUGE amounts of wind, and bad heartburn as soon as my stomach starts to empty. Not happy. Will miss the extremely weird and vivid dreams I got each time though! Back to the doctor tomorrow. Not sure about the pain relief. Hard to notice it when I am so consumed with stomach pains!

I have been using Naproxen for 2 weeks and have horrid stomach cramps and nausea... Think I might give it up... Rather the pain then this feeling.

Took naproxen for 2 days now. Was prescribed for bursitis in my knee. Noticed swelling of my lower leg and ankle in the morning of the second day but didn't make the connection until tonight. So I've officially taken 2 days worth and my ankles and feet are so swollen I can no longer see my ankles. My lower leg is twice the size of the other one.

Stay away from this horrendous medication! I would rather have dealt with the bursitis pain rather than worry about what damage this has done to my body. Should have just taken regular advil for pain.

PEOPLE'S PHARMACY RESPONSE: With such a difference in leg size, you need to be checked right away for a possible blood clot in your leg (DVT)

Swollen limbs bloated stomach.... no thanks.

Been taken 500mg twice a day and pain in lower back got a lot worse and spreading to my hips and legs, very painful when walking, won't be taking them anymore.

have taken 2 500mg tablets yesterday prescribed for arthritis. I'm just gonna stick with the arthritis pain because that is nothing compared to the stomach pains and sick and bloated feeling that these tablets have given me. Please, if they've been prescribed for you ask the doc to change. No tablet is worth the pain I am in right now.

Tried Naproxen 500mg 5 years ago for severe polyarticular gout and felt so ill it was unreal...Went onto Dicloflex 50mg with Colcichine which I only used as and when I could feel an acute attack coming on and have not had a full attack in years and didnt even have to continue seeing my Rheumatologist....THEN went to see my NEW GP for a repeat precription who refused me my normal medication...Prescribed me Naproxen against my insistence with Omeprozole and down dosed my Allopurinol.....I have never felt so ill. Stomach pains...diahorrea then constipation....kidney pains...you name it...and have the worst acute attack ive had in years????wtf??? Changed my GP and reverted back to my usual meds...Naproxen is a dangerous drug...Be warned

my dentist prescribed me naproxen after my wisdom tooth surgery on thursday.
it helped me the first day but the second time i took it, i started to feel like there's acid in my stomach and no matter how much water i drink to dilute it the uncomfortable pain is still there. tonight, i took naproxen at 9pm i felt like am going to die i am having palpitation, i was dizzy with heart burn and i felt like i'm going to throw up! i will never use this drug ever! i tried to have some rest and it kinda help me a bit but i am still uncomfortable! i might go to ER to get help!

I am having the same issues after taking Naproxen, my stomach is bloated beyond belief and is cramping like crazy! How long did your symptoms last? because I am getting scared and its been 2 days and no improvement. I have been drinking lots of water to try and flush it put of my system but it's not seeming to help any.

I am a 16 year old girl who has had some bladder issues since I was eight. I was taken to the hospital for pain in my left hip and the doctor prescribed two pills 500 mg of Naproxen to be taken twice daily.

I complained of pain in my right lower stomach and back. I couldn't sleep at night. Then my bladder shut totally down and has been since Nov, 2012. I also had constipation and my colon will only work with help.

I had taken the drug for almost three weeks before another doctor took me off. I was in the hospital for seven weeks and was just released with no improvement. I know the drug did this to me-has anyone else had these severe reactions.

Hello - Have been taking this for two weeks now 500mgs x 2 daily with breakfast and dinner. Also take a stomach protector. No change to the pain at all, I have inflammatory arthritis, neck, back, si joints, elbow, feet pain.

Side effects minor compared to others here - constipation, bloating which is enough to deal with. Have called my specialist for advice/change to a different medication. I also take 10mgs methotrexate.

I used to take anaprox back in the late 80s early 90s for cramps and would only need 1 pill a month! Now I take the naproxin 500s for my lumbar pain. My tolerance allows me to take them less as in every other day without any problems, but taking it twice a day every day like prescribed slowed my system down too much and would get bloated and backed up.
Now the Tramadol 100s!.......whoa, I rarely take those and have to be really in pain to take one 2 days in a row....like today. Wish I could go back to the Anaprox though.

Previously alternating with ibuprofen and paracetamol. To be honest have not noticed any benefit or worsening effect so far... apart from dry tongue and nasty taste. About to take third day dosage. Am usually sensitive but have found I still need to take 1000mg of paracetamol to get any pain relief. If these are so powerful, how come? Certainly not sleeping any better, still waking up with pain.

I have taken Naproxen 500mg. Twice a day for 3 months for a bulging disc. Pain was still present but not as bad. The side effects of this drug appears to give me constant ring in my ears. I wake up in the night with the buzzing noise. I have stopped taking the drug now for four days and the ringing is still present. How long does it take for the ringing to stop.

Was taking naproxen 500mgs for arthritis, pain developing in my thighs so painful when trying to walk, stopped taking them because legs and ankles were bloated too. Would rather put up with the arthritis pain would never take it again.

I have taken about 12 of naproxen over a period of 3 days for severe backpain and my ankles and lower legs are so badly swollen its unbelievable. My hands are swollen too so much so I can't move my wedding ring. Does anyone know how to get rid of the water retention.? I stopped taking them 24 hours ago when I read about all the side effects.

Started taking this medication about a month ago for sciatica and back pain.

Having all sorts of complaints since then. The worse for me was depression. Two nights ago, I had such bad stomach cramps and bloating I slept on my bathroom floor. I was terrified; I got shaky, hot and sweaty and was so weak I almost fainted.

Today I am in bed all day, not taking this pill ever again. I am so tired, weak, depressed, just wanna die. Hopefully, this passes soon ...I am drinking lots of water today.

I took 2 tablets of naproxen after a big dinner and was woken by really bad colicky pains. I didn't connect it with the tablets until a week later I took another two tablets after a full dinner and again woken at 2am by severe stomach pain. I could only get relief with a hot water bottle. 12 hours later and I'm still suffering bad stomach pain, especially when my stomach is empty. I just hope permanent damage has not been done. I will never have this drug again.

I have taken 3 Naproxen pills (two on Monday one yesterday) for a really bad tooth ache that I had and it has torn my stomach to shreds. The feeling is unexplainable like an extreme hunger pain. The only time I feel relief is if my stomach is really really full. If its not then the pain makes me double over it hurts that badly!! I would never recommend this medicine to anyone! I don't even know why a doctor would prescribe something so extreme for this. It did get rid of my tooth ache but I would gladly take that pain just to stop this hurting sensation in my stomach. Needless to say I will NEVERRRR take this pill again!!!!

My primary care doctor prescribed 500mg of Naproxen to be taken twice daily for a minor toe injury. Barely more than a day later, I've become a miserable diarrhea geyser. The comments here have freaked me out enough to ensure I'll never take this vile drug again.

I've taken Naproxen for almost 20 years for back pain (inflammation). Initially, maybe one over-the counter-pill a day for a day or two or three for flare ups that would occur 3 or 4 times a year. The drug was immensely effective. I considered it a wonder-drug, as it was the only medication that really worked -- and I tried almost everything available (prescription and non-prescription). And there were no adverse side effects. As I've aged, my back conditioned has worsened, requiring more and more Naproxen.

Recently, I has been taking a lot more because back flare-ups were occurring a lot more often; and now, partially as a result, I've developed ulcers. My doctors are telling me to stop Naproxen altogether. And, for the most part, I have. Occasionally, however, I have taken a little here and there when back discomfort is particularly bad. But this does not seem to upset my ulcers. At least there has never been an instance where I took a Naproxen and then suffered with upset stomach right away.

There have been times when 3 or 4 days after dosing with Naproxen that stomach issues have presented. But because of the amount of time between Naproxen dosing and stomach issues, it's hard for me to believe that Naproxen is the cause. If anyone else has experience like this, and can comment, I would appreciate knowing what you have to say.

I have been on steroids and 500 mg of naproxen twice a day. I suffer from tarsal tunnel syndrome and have not found any relief looking at surgery in September. The first two times taking naproxen I experienced the stomach ache which was nowhere near as bad as my feet/ leg pain. My stomach isn't upset anymore but honestly no pain relief. Sometimes I think I've been prescribed the wrong drugs because my pain is sharp burning and numb/ can't feel parts of my feet the parts I do feel seem like they are on fire!

Naproxen was the pits -- doctor aware my stomach issues with Volataren and prescribed this and I was okay for 4 days then bam - hit me like a truck - very bad pains in stomach, constipation, dizziness, nausea - stopped immediately along with the paracetemol he also had me on - this was for a back injury. Now 5 days later beginning to come good but not quite there yet.

I have been taking NAPROXEN for 2months, 34 tablets in total I don't read the leaflets you get with meds but after taking NAPROXEN I will read everything first, not that the leaflet told you very much.

I was given NAPROXEN for a nerve injury. I was told the symptoms would get better HA! HA! Have stopped taking the pills but have been left with a lot of problems.

Extreme hair loss. Seeing and hearing things that are not there. Excessive tears. Cold sweats. Confusion. Sore throat hoarseness. Diarrhea. Extreme fatigue. Increased sensitivity to skin in sunlight. Increased sweating. Lower back and side pain.
Inability to sleep.

But When you do sleep the nightmares are bad / headaches / increased thirst / Changes in hearing. All this from one little tablet. The worst is the hair loss and i mean a lot of hair not at the beginning just in the last 2weeks.

I really didn't think tablets could do this in such a short time. Could any one tell me how long it takes to get rid of the side affects especially the hair loss.

I took Aleve one time, I had an immediate side effect - ringing in my ears and then diarrhea. It's been over a month now and no relief in the diarrhea. I go to the GI doctor next week.

I took 2 Aleve one time a month ago for knee pain. Within a half hour I was dizzy and had ringing in my ears so bad I couldn't fall asleep. The next morning I had bloating, gas, and diarrhea and it hasn't stopped. I go to the GI doctor next week.

It has ruined my life. I'm so afraid of getting caught too far from a restroom as the diarrhea comes on suddenly. I get relief when I take Kaopectate but I don't want to live on that. And as soon as I stop taking that, the diarrhea is right back.

I'm looking for a cure as I can't imagine living like this forever. A month is too long.

Started my course of Naproxen last night about 40 minutes after taking it with a drink and dinner started to get burning in my stomach, feelings of dizziness and palpitations. I had read the leaflet before hand so I knew these things were possible but I have made the conscious decision to not take any more and go back to see my doctor first thing tomorrow morning.

I'm only taking it for sinus and inner ear inflammation along with Anti Biotics. I must admit the relief the tablet gave was good, but it's certainly not worth some of the side effects being muted on here. It's been about 16 Hours since I took it and my stomach is still burning now with very little relief from water, milk or over the counter indigestion products. I am flushing my system with regular Water and Green Tea's in the hope that this goes away quickly. I have no intention of taking the remainder of the 55 tablets I have left, I wonder what state I'd be in if I did?

I was prescribed naproxen for my costrochondritis after ibruprofen wasn't helping I took it with omeprazole but still had stomach ache indegestion for 11 days after I stopped taking it for 5 days!!! Silly me got prescribed a coated naproxen tablet next have now been stupidly ill for 14 days and counting after just taking 5 of these pills.... Indigestion you wouldn't believe???

Please if you feel any pain or it feels like you've swallowed a sock STOP taking these bastards your in for a personal hell!! I've taken Liver salts twice a day and at least drank 1.5 litres of water a day but still feel like I've swallowed a firework???? Hope this don't happen to you but it could so don't take the risk.

Hi
Has the ringing/buzzing in your ears stopped, if so, how long did it last and what would you recommend to clear this up as I have taken Naproxen for two weeks and have the same issue
Good luck and I hope it cures itself asap.

Hi Mimi

I read your comments "I took Aleve one time, I had an immediate side effect - ringing in my ears and then diarrhea. It's been over a month now and no relief in the diarrhea. I go to the GI doctor next week"

Has the ringing in your ears now subsided, if so, how long before it went away, I have been taking Naxproxen for about two weeks and I now have ringing in my ears !! I have now stopped taking this drug.

Took just a few of these pills prescribed for arthritis never again got bloating, severe stomach cramps, heartburn and headaches it also made me feel a little bit spaced out as well won't touch again, besides that it did nothing for the pain.

I was in a car accident, my dr put me on naproxen 500mg to take 3 tabs per day, on the second day of taking the medication, I had to go to the hospital, my stomach pain was so bad, and got black stools followed by diarrhea. The pain was so bad I thought my stomach was trying to eat itself from the inside out.... Won't ever take this again.

Alleve is the only pain medication that brings me any relief but I don't take it on a regular basis. I've gone to the ER in the past for migraines and gotten shots that would knock me out. I would wake up hours later in as much or more pain than before. I had a prescription for naprosen after a surgery and took one the next time I had a migraine. Within a few hours, I was back to normal. I didn't go through hours of pain, nausea, light sensitivity and vomiting that usually accompanied my migraines. I have learned to take two 220 mg Alleve when I first feel one coming on and haven't had any problems since.

I just had my first bad experience but it really is my own fault. Yesterday I took 1320 mg throughout the course of the day so I could function due to excruciating menstrual cramps. This morning I thought I would have to miss work due to the stomach upset. I normally have very regular bowels and I have never been as constipated as I was today.

So for me it has been a lesson learned. I will continue to use Alleve as needed. I probably have 5-6 migraine episodes a year - down from 20-30 in the past. Alleve works for me but I will definitely not over-medicate again!! Lessons learned the hard way always stick!

I had neck surgery after a year of pain. I was taking naproxen 3 times a day, everyday for a few months. I have now developed Porphyria Cutanea Tarda. I am surprised I am not reading more about others with this problem. My hands are breaking out terribly with blisters. I went in to see a doctor and immediately was ask how much naproxen I am taking. It has been a month and I have not taken a bit. I am told my hands will continue to break out for a couple of months. This is horrible. I am also attaching a link to a picture of what my hands look like. This is not my hands and this lady was also getting into a tanning bed...I have not. I just work outside delivering the mail. Please let me know if anyone else is experiencing this problem.

http://en.wikipedia.org/wiki/File:Pseudoporphyria.JPG


Take Care

Tracy

I was taking naproxen a few times a day due to neck pain. After a year, I had surgery and 2 disks replaced. I have stopped taking the naproxen and now my hands have broken out with blisters. I went to the doctor and he immediately ask me how much naproxen I was taking. I was diagnosed with Porphyria Cutanea Tarda brought on from taking naproxen.

I started doing research and found so many people with this same problem. I found pictures that looked exactly like my hands. I was also told that my hands could break out every time I am in the sun for months. I have to keep them covered and wear sun screen. I work outside delivering mail. This is a huge issue. My hands are so sore. I had never even heard of this before now. As I do research it seems to be common. I think this should be a warning with this medication.

I was prescribed this medication for my micro ligament tear in my knee (500mg twice a day). It definitely helps with the pain, for a few hours, but then it wears off and I end up back in excruciating pain for a few more hours until I can take it again. I find it difficult to concentrate in school and my friends have noticed me zoning out a lot since I took it. Also, in the middle of laying down to go to bed for my second day taking it, my stomach suddenly made a weird rumbling noise and I had to run to the bathroom. Many stomach problems from it. I did follow directions and ate a drank water before I took it but it didn't avoid the stomach problem. I do not recommend it.

I was prescribed Naproxen 500 as an alternative of Ibuprofen for an elbow pain. I took the first tablet this morning as prescribed and the pain was almost gone. But after about 5 hours, I had a snack and, immediately I got pain in stomach and diarrhoea. I expected that it is due to this medicine. After I read the comments here and after suffering from the pain I have now while I'm writing, I decided to stop taking it and I'm telling everyone 'please do not take it'.

People's Pharmacy response: Naproxen (Aleve) is an NSAID, and like other NSAIDs, it can and frequently does cause digestive tract upset. You are clearly more sensitive to this problem than some other people, and it makes sense for you not to take it. Others may need to make their own determination.

I have been on Naproxen for several months for back pain and was believing it to be a wonder drug, until 3 days ago.

I am so bloated I haven't been able to eat anything for 3 days and only just managed to swallow enough fluids to get my other meds down. I am now wondering if it is the Naproxen even though I have been fine before. I also feel nauseous with horrendous heartburn.

I went to my doctor for my chest being so tight shortly after starting this drug because it was scaring me and she said everything was fine. At 54 I believed the sweating was me starting the change. It still might be but I am now wondering. My sleeping has always been disturbed as I also suffer from depression and ptsd.

This site has opened my eyes to the possibility that Naproxen may be the cause of these symptoms but do I continue to take them because these symptoms, although very bad are not as bad as the original back pain. I am very overweight so the thought of losing weight is quite appealing.

Update from my post on 9/17/13
The ringing in my ears only lasted 24 hours but I had only taken 2 Aleve.

I did have a colonoscopy done with biopsies and the colonoscopy was normal but biopsy showed a rare condition called Lymphocytic Colitis. Which from some of the reading I've done can be triggered by NSAIDS (naproxen, ibuprofen,aspirin)

I began taking a steroid - 3 mg of Budesonide EC 3 times a day on oct 30thand I started getting relief from my colitis about a week ago. It is definitely working. I take that dose for 4wks, then 2 per day for 2 wks, then 1 per day for 2 wks. And hopefully I'll be back to normal.

I hope this is helpful.

Really helped with severe pain within 2 doses but made me extremely sick at night. Terrible stomach cramps with nausea and vomiting! Stopped taking them then and immediately felt less nauseous!

I was prescribed naproxen 500gm twice a day for costochondritis, took it with meals for about 4 day and my inflamed ribs now feel much better. However since coming off it I've had stomach cramps, wind and a bloated feeling (and looks it!). Eating a large meal tends to help the cramps but I don't want to keep this up. Going to do 24 hours of water only tomorrow and see if anything changes, if not, probably back to the docs next week.

Just taken my first 500mg of naproxen tonight and wished I'd read what people's side effects had been first as so nervous now been in my system about a hour really hoping I get no bad cramps are anything else as need to find a good pain relief for my chronic back pain.

I have been taking Naproxen 500mg off and on for the past 2 months and have been noticing hearing loss and a loud ringing in my ears. I stopped taking it today after reading the comments on this site. I'm hoping that these effects will reverse.

only took 2 of the prescribed 70 tablets, severe sickness and stomach pain after the first one, but after the second dose I sunk into severe depression, began hallucinating and became seriously suicidal. It was as if I was experiencing my worst nightmare while awake! This was 3 days ago, and I am just beginning to feel normal again, am now taking a homoeopathic detox to try to remove it from my system.

This product worked good with my teeth pain but gave me diarrhea and ringing ears. Just bought a bottle of 100. They're going in the trash

I took naproxen and my ankles and feet swoll up for about 5 days.

I had been taking 500 mg of Naproxen twice a day for 3 months about 5 weeks a go I started getting chest pains and stiff tensed lower jaw at same time thought I was having a heart attack this happened 3 more times always when just sitting relaxing in the evening watching tv I finally went to the doctor convinced it was my heart saw a locum doctor who straightaway said it was the naproxen causing it examined my tummy found my stomach to be tender saying it may have caused an ulcer - put me on paracetamol instead but quite honestly I am now scared to take any pain killers - be aware people doctor does not always know best I also felt very depressed, couldn't sleep very wheezy but I also have asthma anyway, had small bruises appearing on my body very dark black ones, I feel anxious and get stressed easy over little things - have only stopped taking them yesterday dread to think how long it will take to get rid off the effects.

I have early stages of carpel tunnel syndrome. My doctor prescribed naproxen 500 mg for two weeks. The first day that I took the drug I felt an immediate fullness in my stomach. Thinking that the fullness was caused by something I ate, I continued taking the medicine for a couple of days. I stopped yesterday but symptoms have not improved. Feel gnawing pain in pit of stomach. I am extremely gassy. I am constantly running to the toilet during the day. Wake up in middle of the night feeling nauseous. My mood is irritable. I honestly thought that I must have some kind of disease until I read this post. My appetite dropped. I am taking the advice of some who posted and drinking a ton of water. I hope it has not done permanent damage. I eat very well and exercise regularly. This drug is not for me. I am just hoping that this discomfort goes away soon.

Have been prescribed Naproxen (250mg twice a day) to help with bowel/hernia problems and now have bad diarrhoea and burning pain in my abdomen. Am not going to take it any longer as really feeling bad with it. No energy and unable to sleep. Be warned people out there when going on these drugs. Try do NOT suit everyone.

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