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Losartan

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Overview

Cozaar is the first of a new kind of blood pressure medicine, an angiotensin II blocker.

Cozaar is prescribed for high blood pressure, alone or in combination with other drugs. It appears to be less effective for African-American patients.

Side Effects and Interactions

People on Cozaar have experienced dizziness, insomnia, muscle cramps or pains, nasal congestion and sinusitis.

Other side effects reported include faintness, low blood pressure, diarrhea, indigestion, and chest pain.

Dizziness or faintness may be worse if a person becomes dehydrated through excess sweating, diarrhea or vomiting. Report any symptoms to the physician promptly.

Cozaar is not appropriate during the second or third trimesters of pregnancy. If a woman taking Cozaar becomes pregnant, she should consult her doctor as soon as possible. Nursing women should not take this drug without first discussing potential risks and benefits with their physician.

Tagamet may increase the level of Cozaar slightly, while phenobarbital reduces it. Interactions with other drugs such as erythromycin, Nizoral, or Sporanox have not been documented but are theoretically possible.

Cozaar is metabolized by CYP enzymes in the liver. As doctors gain more experience prescribing this medicine, more interactions may come to light. Check with your doctor and pharmacist to make sure Cozaar is safe in combination with any other drugs you take.

Special Precautions

People with liver disease may have trouble metabolizing Cozaar. The dose should be adjusted accordingly.

Taking the Medicine

Cozaar may be taken when convenient, with or without food.

It is taken once or twice a day, according to the prescription.

  • Currently 2.9/5
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Did this drug work? Average rating: 2.9/5 (17 votes)
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19 Comments

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I have been taking 1 Cozaar tab 100 mg sometimes for elevated blood pressure. My regime includes 1Triam/HCTZ 25mg, 2 days on and 1 off and Atenolol 25mg 2X a day. It is suggested by my physician that I replace the Cozaar with 1 Hyzaar tab 100/12.5, which has contains the diuretic. Would you consider this a viable change? Thank you.

Why is a prescription not filled with the generic version if there is one. I am currently taking Cozaar and it is expensive. Above you mention the generic is Lorsartan. When I asked the pharmacist he said Cozaar is not yet available in a generic form. I'm confused about why it isn't.

My cardiologist prescribed losartan 50mg daily. She said that this generic form of cozaar has just recently become available. My pharmacist says it is not available yet. Who is right?

Like so many on this site before me I take Cozaar and would like to switch to geneic Losartan Potassium. I have recently changed from Crestor to Simvastatin and saved about $100 a month. With a change to generic Losartan I could save an additional $100 per month!

Right now the doctor and I are checking to see if there are any side effects with the Crestor change before we look at changing the Cozaar in about a month. Wish me luck, if the switch can be made I will effectively save $2,400 a year in cold cash.

My mother is taking Cozaar and I would like to switch her to generic, but it's not available in the U.S. according to two different pharmacies. She is also taking Aricept and I got the same information. However, I have found generics in Canada. BUT, I also found an article warning not to take the Aricept generic because it might not be safe. I believe both drugs will not be available in generic form (at least in the U.S.) until 2010.

I have been taking 100 mg Cozaar for almost three years now. I workout and jog a few times per week. I recently started getting a tingling feeling in my lower legs and every now and then my lower back feels tight. I had my last blood test in November and my BUN and Creatine levels were slightly above the normal range. I think that this Cozaar is slowly but surely decreasing my kidney function. I am pretty close to getting off of all medication because I do not want my vital organs destroyed by a drug that is supposed to help me. Has anyone else had the same experience or can help me with an answer?

My doctor just prescribed
Losartan. My pharmacy says it is not yet available. Why are doctors prescribing it if it is not yet available?

PEOPLE'S PHARMACY RESPONSE: LOSARTAN IS THE GENERIC NAME FOR COZAAR. THE PRESCRIPTION COULD BE FILLED WITH THE BRAND NAME DRUG.

I had been taking Toprol XL and Cozaar for over 2 yrs. until July, 2008. Due to muscle weakness in my legs and difficulty getting up and down, I requested for a change in medication last July. I didn't realize my heart palpitations would recur. After having tried Verapimil, Amlapidine (generic to Norvasc) and Tekturna, my heart palpitations continued and I returned to taking Cozaar (50 mg.). The medication was increased to 100 miligrams shortly thereafter and I now have severe muscle hurting in my back (mostly lower back) and leg muscles. I need to be taken off Cozaar, but do not know of a blood pressure medicine that would not cause heart palpitations to recur. Has anyone had the same problem and do you have any suggestions?

Our pharmacy just filled my husband's Cozaar prescription with Losartan instead. Since we are currently paying out of pocket, we appreciate the savings, but I'm wary of him taking a generic. Has Losartan proven to be a good generic option, or is it one of those that has its own set of side effects?

NOTE: My husband had a stroke last year, and although he is doing well now, he has previously had an extremely severe reaction with angioedema of the lips (he was not taking any medications at that time, so we're not sure what caused that reaction). Needless to say, I'm concerned with any change in his medication regimen since a repeat angioedema reaction could prove to be fatal.

I took Cozaar for about 7 years and for the last 5 years, had a painful throbbing in my feet. It was most severe upon going to bed at night. Was prescribed amitriptyline to allow me to fall asleep. On a trip, I ran out of my prescription and was surprised when for a few nights I comfortably fell asleep. Upon returning home, I decided to test whether or not Cozaar was the cause of the throbbing. One night taking the med, one night off for a week. On the nights I did not take Cozaar no pain. Then I tried 2 nights without and 1 night on. The results were the same. No pain the nights without Cozaar. An attempt to take Cozaar in the morning as recommended by my doctor, resulted in dizziness leaving me unable to navigate.

I have been taking Diovan since 2004; Recently, we have had to pay out of pocket for our meds; my Dr. put hubby and me on lisinopril; my husband had no problems; I coughed almost non-stop. My Dr put me on losartan (generic by teva); day 2 my heart began to skip some; it would race some; it would pound some; it would take my breath away when it pounded two or three times; as the days went on the seldom-occurring jumping or pounding got more frequent.

Then, on day 8 (YESTERDAY) my heart would pound and race and jump and I just could not take it any more; (it was just like I had very low blood sugar! I have had 3 glucose tolerance tests over my lifetime and I felt the same way during those!). I am not diabetic and stay in the 90's.

So, this morning I refused to take another losartan; here it is nearing noon and I feel better; I put in a call to my doctor and told them I refused to take another losartan! my glucose is 94, my bp is 105/69 with 64 pulse. When I took losartan, within a couple of hours, my heart would begin to jump, or race or pound . I have to pay out of pocket and do not know any other Rx to try in a generic to save money; I am also wondering if the TEVA generic has anything to do with the problems.

I just do not like the way I felt taking those 8 day's worth of losartan!

As for Teva generic losartin causing problems, I have heard this before. I take losartin by Roxanne with no problems. If you check FDA records you will find that Teva is a drug company that has had many run ins with the FDA. If you try another generic for losartin you may not have any problems.

Side effects for me were edema, very swollen face, neck, eyelids seriously drooped. Burning feeling on face and neck. This was after only 14 days of Losartan. Have been off medication for 5 weeks, still have issues with eyes and neck. Seems the cure is eyelid surgery according to my eye doctor and MD. That's serious to me as that would be the last resort. Read RX print out and keep track of side effects listed for Losartan. (and all RX's)

I am taking cozaar 50mg in the am with 5mg of norvasce and was taking 2.5 mg of norvasce at night--Dr. took me off norvasce at night and put me on 25mg of cozaa--since then my blood pressure has gone up to 173 over 90 and I have not been able to sleep well and have tremors in my thighs and sore eyes-- and my Dr. wants me to take 50mg at night--I believe that I cannot take ace inhibitors for my body cant tolerate the side affects as when taking bystolic, I wheezed and coughed so much it was thought I had heart problems which I did not--what can I do, I am in the 2nd stage of chronic kidney disease and have had one kidney removed due to cancer and need to protect the other kidney--I want my blood pressure to be normal and I want to feel good from the meds.

I had two stents put in back in 2004. They tried to get a third one in but punctured the sack around my heart and gave me a heart attack. I was put on Cozaar (25mg.) and 25mg. of metoprolol. For the last three years I've only been taking 12.5mg of metoprolol a day. I've only been taking 25mg. of cozarr every other day. I'm doing this on my own. The pharmacy switched to losartan.

It was still a green pill. A few months ago I had my losartan refilled. It was now a white round tablet. I've been having muscle and bone pain and I'm having trouble breathing. I had a echo cardiogram yesterday. Today they called and told me to stop the losartan.

My blood pressure usually runs 118. High for me is 129. I can hardly wait to get off this crap. I'm always tired. I walk 2 miles a day and really have to push myself. Do your homework and do your own research. I never had high blood pressure in my life. It wasn't until they did a bang up job with the stents that I was put on all this junk.

I am taking 50 mg of Losartan for BP and I am certain that my lethargy and drowsiness, dry mouth and dream abnormality is being caused by it. The dreams are bizarre and disturb my sleep.

Today is day 7 of Losartan for the second time; ~~I tried it almost a year ago (to save money);~~ before, it caused rapid heart and jumping and low blood sugar feelings;
THIS time, I am trying it because diovan costs $90, and lisinopril ($4 and enalapril $4) made me cough and cough and cough to the gagging point; it would make me wake up in the night gagging and grabbing my neck where the itching and tickling was; ~~ back to my dilemna: SO, my Dr. put me on losartan again; he begged me to try it; it is $48.

HE TOLD ME THAT IT does not cause coughing; WELL, I am coughing as much as on lisinipril. I stopped lisinopril for a couple of weeks and took enalapril; less coughing but still was coughing; then I started the losartan; it is horrid coughing in spells; I emailed my Dr today and he said losartan just does not cause coughing but to stop it for a few days; ~~~from what I am reading in this fabulous website, it CAN and it does cause coughing!~~~ and that I could still be coughing from the lisinopril from a few weeks ago; what if I have overlapping coughing from everything? my b/p goes to high 130's over high 80's when off the Rx. ANY suggestions; I pay for all prescriptions outta pocket.

I have been taking Losartan for over a year First 25 mg,then 50mg and now 100mg the magic number that has bought my BP down to 120/74. So far very little side effects sometimes dry mouth, Sometimes dizzy but usually first thing in the morning if very hot humid weather is in the area. Since cutting out added salt to my food I have had no problem with feet or ankle swelling. Lately I have been sleeping like a baby.

I have been on several meds and can't handle the ones with HCT at all. Couldn't get out of the chair and thought I would faint when I bent over.
Doc put me on Losartan (cozar) 50 mg and BP still high in a.m. and periodically through out the day with no rhyme or reason. Went to 100 mg and am having trouble getting to sleep although exhausted and requiring 12 hrs of sleep and still tired. I would go to bed with no foot pain and wake in the night with joint and foot tingling and was concerned about circulation.

Now I read about the foot problems some report and that is what I am having. My systolic is down with the 100 mg but the diastolic is not much improved and it is the one that counts more. I feel like something is draining the energy out of me and I am going to stop taking this and try some natural supplements. I am not going to take three meds for BP as they all have side effects. I feel so tired I can't exercise and I know that it is really important that I use my rowing machine. This is a catch 22.

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