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Overview
Amoxicillin is the most commonly prescribed antibiotic in the United States. Unfortunately, the widespread use of this penicillin-like drug has led many bacteria to develop resistance to it.
By adding clavulanic acid to the formulation, scientists created a medication, Augmentin, that is effective against many bacteria that are not susceptible to amoxicillin alone.
This broad-spectrum antibiotic is effective in fighting infections in many parts of the body including the urinary tract, skin, sinuses, lungs, ears, throat and genital tract.
Side Effects and Interactions
The most common side effects of Augmentin involve digestive tract upset. Nausea, vomiting and diarrhea can be troublesome for some people.
Other adverse reactions to be aware of include skin rash, itching, vaginal infections, stomachache, gas, headache and vomiting.
Less common but possibly more serious side effects include liver enzyme elevations, anemia, blood disorders and psychological reactions. Report any symptoms to your physician promptly.
Long-term treatment with penicillin-type antibiotics requires periodic monitoring by a health professional.
Augmentin may interfere with some urine tests for diabetes and produce false positive results.
Augmentin should not be taken with tetracycline or some other antibiotics. Notify your doctor if you are on such a drug for a different condition.
Special Precautions
Because amoxicillin is related to penicillin, anyone who is allergic to this class of antibiotics must generally avoid such drugs like the plague.
Symptoms such as breathing difficulty, wheezing, sneezing, hives, itching, and skin rash require immediate emergency treatment.
Life-threatening anaphylactic shock may produce an inability to breathe and cardiovascular collapse and can occur within minutes of exposure.
If you experience a serious reaction and you ever have to go into the hospital, make sure a sign is placed over the bed alerting hospital personnel to penicillin allergy.
Taking the Medicine
Augmentin can be taken with meals or on an empty stomach. It is generally best swallowed with a full eight-ounce glass of water.
To maintain adequate levels of the medicine in your body, it is usually recommended that doses be given every eight hours.
Check with your pharmacist to see how you should adjust your schedule to get the third dose in on time.

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I was given Amox TR-K CLV ( Generic for Augmentin ) 500mg three times a day for five days, for a dog bite on the lip, is this a long enough course of this antibiotic?
I was given Augmentin for a sinus infection and because I had an infected puncture wound on my palm from my cat clawing me. 6 days into treatment I developed a rash that started on my back and rapidly spread to my whole trunk... two days later it was going down my arms and legs. Now it is over 3 weeks later and I am on steroids to calm down the severe rash reaction I had to the augmentin. Can I assume that I am allergic to Penicillin? As a child I was given penicillin shots many times with no bad side effects. Have I developed an allergy?
PEOPLE'S PHARMACY RESPONSE: YOU AND YOUR DOCTOR NEED TO TALK ABOUT THIS. IT IS POSSIBLE YOU MIGHT HAVE DEVELOPED AN ALLERGY TO PENICILLIN, BUT YOU ALSO MIGHT BE REACTING TO THE OTHER COMPONENT OF THIS DRUG.
I was prescribed by a dentist with augmentin. I've been taking my medication for 10 days when itchy skin rashes appeared. First it was only on my legs then it spreads to my body, my nape and neck, then on my arms and back.