Overview

Amoxicillin is the most commonly prescribed antibiotic in the United States. Unfortunately, the widespread use of this penicillin-like drug has led many bacteria to develop resistance to it.

By adding clavulanic acid to the formulation, scientists created a medication, Augmentin, that is effective against many bacteria that are not susceptible to amoxicillin alone. This broad-spectrum antibiotic is effective in fighting infections in many parts of the body including the urinary tract, skin, sinuses, lungs, ears, throat and genital tract.

Side Effects and Interactions

The most common side effects of Augmentin involve digestive tract upset. Nausea, vomiting and diarrhea can be troublesome for some people. Other adverse reactions to be aware of include skin rash, itching, vaginal infections, stomachache, gas, headache and vomiting.

Less common but possibly more serious side effects include liver enzyme elevations, anemia, blood disorders and psychological reactions. Report any symptoms to your physician promptly.

Long-term treatment with penicillin-type antibiotics requires periodic monitoring by a health professional.

Augmentin may interfere with some urine tests for diabetes and produce false positive results. Augmentin should not be taken with tetracycline or some other antibiotics. Notify your doctor if you are on such a drug for a different condition.

Special Precautions

Because amoxicillin is related to penicillin, anyone who is allergic to this class of antibiotics must generally avoid such drugs like the plague.

Symptoms such as breathing difficulty, wheezing, sneezing, hives, itching, and skin rash require immediate emergency treatment. Life-threatening anaphylactic shock may produce an inability to breathe and cardiovascular collapse and can occur within minutes of exposure.

If you experience a serious reaction and you ever have to go into the hospital, make sure a sign is placed over the bed alerting hospital personnel to penicillin allergy.

Taking the Medicine

Augmentin can be taken with meals or on an empty stomach. It is generally best swallowed with a full eight-ounce glass of water.

To maintain adequate levels of the medicine in your body, it is usually recommended that doses be given every eight hours. Check with your pharmacist to see how you should adjust your schedule to get the third dose in on time.

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  1. Evelyn Goins
    North Carolina
    Reply

    I was prescribed Amox-Clav(Augmentin) for 5 days for urinary tract infection and after 3 days developed a blistering type clusters on eyelids,above eyes, below eyes and on areas of face. This itchey rash leaves skin looking like you had a bad sunburn with scaling, also stomach pains and cramping, bloating and diarrhea. I did finish taking however, I will definitely will not take again.Still recovering. I am 80 yrs. old(female).

  2. Judith
    Baldwin
    Reply

    I am also taking Augmentin now and have felt nauseous and have had stomach pains that feel like severe gas expanding my stomach. I have taken Amoxicillin alone many times with no side effects at all. I also stopped taking the Augmentin after the second day when I took it on a partially empty stomach and felt worse than the condition I was taking it for was making me feel. I have 3 days left and believe me I have put on weight over the last week just from ensuring my stomach is full before I take it. Seems nuts. I am going to contact the pharmacist and see if they can give ma an alternative to finish out the week. The symptoms of the sinusitis I am taking the med it for are reduced but have not been eliminated. smh

  3. Maddie
    Queensland, Australia
    Reply

    I was prescribed AmoxClav for a sinus infection. I took the first one and a few moments late, I got an intense fever with sweats – my body just kicked all the bugs out of it! My stomach is so painful, nothing helped, not even paracetamol or nurofen. I had to take my 2nd dose lastnight :s I couldn’t sleep because of the stomach ache! It was so unbelievably unbearable, I almost cried…and I’m the type that can tolerate loads of pain. I mean, I was laughing through childbirth for goodness sakes! My sinus infection is still there, but I’m tempted to just give up on these certain antibiotics.

  4. Susan
    texas
    Reply

    I took Augmentin in May 2014 for what I thought was a sinus infection. Three days into taking it I was extremely nauseous and couldn’t eat anything but bread. I felt so horrible that I stopped taking it (after 3 days) even knowing you are supposed to take all of a prescribed antibiotic.

    My urine turned a dark, dark orange color and smelled like smoke. (I don’t smoke.) I went to my doctor and she did a urine test and discovered blood in my urine, but no infection and no signs of cancer cells. I then had to go to a Urologist for a kidney ultrasound and a bladder scope to see if there was anything wrong that they could see. Fortunately everything checked out OK and I’ve gone to the urologist every 6 months since then and they still detect blood in my urine (the mircro kind —not like you can see blood).

    I am tired or worrying about this and tired of not knowing what happened. All I know is that I was fine before I took Augmentin and I haven’t been fine since.
    If anyone has any insight, I would be very grateful.

  5. Shawnda
    GA
    Reply

    I am currently taking this medication for an ear and sinus infection. Day 1 and so far no problems and praying for nine more days problem free. Will keep you guys posted!

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